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Current Melanoma News and Events, Melanoma News Articles.
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Study reveals first evidence inherited genetics can drive cancer's spread
Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. (2020-05-25)
Examining melanoma risk in patients treated with biologics for common inflammatory diseases
This study combined the results of seven studies and compared the risk of melanoma among 34,000 patients treated with biologics and 135,000 patients treated with conventional systemic therapy for rheumatoid arthritis, psoriasis or inflammatory bowel disease. (2020-05-20)
Genetic origins of hybrid dysfunction
Evolutionary biologists studying populations of hybrid fish have found two genes that contribute to melanoma - only the second time people have identified specific genes associated with dysfunction in hybrid vertebrates. (2020-05-14)
Antihistamines may help patients with malignant melanoma
Can a very common allergy medicine improve survival among patients suffering from the serious skin cancer, malignant melanoma? (2020-05-11)
Interleukin-12 electroporation may sensitize 'cold' melanomas to immunotherapies
Combining intratumoral electroporation of interleukin-12 (IL-12) DNA (tavokinogene telseplasmid, or TAVO) with the immune checkpoint inhibitor pembrolizumab (Keytruda) led to clinical responses in patients with immunologically quiescent advanced melanoma, according to results from a phase II trial. (2020-05-06)
Activating an estrogen receptor can stop pancreatic cancer cells from growing
Activating a receptor found on the surface of many normal and cancer tissues can not only stop pancreatic cancer from growing but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy (2020-05-04)
Continuous dosing improves progression-free survival for melanoma patients with common mutations
A first-of-its-kind randomized clinical trial offers strong and perhaps surprising evidence that a combination of two targeted melanoma drugs when given continuously keeps patients' cancer from growing or spreading longer when compared with intermittent treatment, according to study results to be presented at the 2020 virtual annual meeting of the American Association for Cancer Research. (2020-04-27)
Scientists double understanding of genetic risk of melanoma
A global collaboration of scientists has more than doubled the known number of regions on the human genome that influence the risk of developing melanoma. (2020-04-27)
Comprehensive tumour immunity map opens up immunotherapy to more patients
Scientists have developed a new way to map the molecules on tumour cells that flag their presence to the immune system, according to a study published today in eLife. (2020-04-21)
Turning cold tumors hot: Drug delivery system makes immunotherapy more effective
A new drug delivery system from PME researchers turns 'cold' tumors hot, letting the body's immune system attack hard-to-treat cancers. (2020-04-14)
Missing BAP1 gene associated with immunosuppressive molecules in uveal melanoma
New study from researchers in Finland and the United Kingdom reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas (UM). (2020-04-09)
Immunotherapy prior to surgery is effective in colon cancer
Patients with colon cancer, but no distant metastases, can benefit from a short course of immunotherapy while waiting for their surgery, as it can cause tumours to shrink substantially or clear up in a very short time. (2020-04-06)
New artificial intelligence system can empower medical professionals in diagnosing skin diseases
Researchers in Korea have developed a deep learning-based artificial intelligence (AI) algorithm that can accurately classify cutaneous skin disorders, predict malignancy, suggest primary treatment options, and serve as an ancillary tool to enhance the diagnostic accuracy of clinicians. (2020-03-31)
Combination creates powerful central memory T cells for cellular therapy
MD Anderson researchers find that treating T cells with panobinostat and IL-21 re-programs them to a powerful central memory T cell type that persists longer. (2020-03-25)
Melanoma is killing fewest Americans in decades
Advances in treatment have led to the largest yearly declines in deaths due to melanoma ever recorded for this skin cancer, results of a new study suggest. (2020-03-19)
Cancer: The immune system attacks tumors remotely
How does the immune system act to limit tumor development? (2020-03-12)
Engineered bone marrow cells slow growth of prostate and pancreatic cancer cells
In experiments with mice, researchers at the Johns Hopkins Kimmel Cancer Center say they have slowed the growth of transplanted human prostate and pancreatic cancer cells by introducing bone marrow cells with a specific gene deletion to induce a novel immune response. (2020-03-05)
Bereaved individuals may face higher risk of dying from melanoma
Individuals who experience the loss of a partner are less likely to be diagnosed with melanoma but face an increased risk of dying from the disease, according to research published in the British Journal of Dermatology. (2020-03-04)
Study examines potential link between partner bereavement and skin cancer
Psychological stress has been proposed as a risk factor for melanoma, but clinical evidence is limited. (2020-03-04)
Study suggests blocking immune T-cell regulator may help eliminate tumours
Immune system T-cells are more able to destroy skin cancer cells when a T-cell regulator called SLAMF6 is missing, a new study in eLife shows. (2020-03-03)
A novel cause of fatty liver in lean people
Nonalcoholic fatty liver disease (NAFLD) is mostly diagnosed in overweight and obese people. (2020-03-03)
Nanosize device 'uncloaks' cancer cells in mice and reveals them to the immune system
Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems. (2020-02-26)
Gold nanoparticles detect signals from cancer cells
A novel blood test that uses gold nanoparticles to detect cancer has also been shown to identify signals released by cancer cells. (2020-02-26)
Study reveals potential new treatment for patients with metastatic melanoma
Researchers at the University of Cincinnati have uncovered a potentially more beneficial treatment regimen for patients with metastatic melanoma. (2020-02-26)
Still a fan of the golden tan?
Social media smarts could make you less susceptible to skin cancer as new research shows that media literacy skills can help change people's attitudes about what is believed to be the 'tanned ideal.' (2020-02-25)
Predicting immunotherapy success
Weizmann Institute of Science researchers have now identified new markers that can help predict which patients have a better chance for a positive response to immunotherapy treatments. (2020-02-18)
Targeting turncoat immune cells to treat cancer
A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor. (2020-02-18)
IU researcher makes skin cancer discovery
An Indiana University cancer researcher has identified eight new genomic regions that increase a person's risk for skin cancer. (2020-02-18)
Study identifies states with highest rates of melanoma due to ultraviolet radiation
A new study finds a wide state-by-state variation in rates of melanoma caused by ultraviolet (UV) exposure with highest rates in several states on the East and West Coast including Hawaii, but also a few landlocked states, including Utah, Vermont, and Minnesota. (2020-02-17)
Scientists have identified protein involved in progression of lung cancer and melanoma
Scientists from Far Eastern Federal University (FEFU, Russia), University of Geneva (Switzerland), Minjiang University, and Fuzhou University (China) pointed out WDR74 protein playing an important role in lung cancer and melanoma primary tumors/metastases progression. (2020-02-14)
Prebiotics help mice fight melanoma by activating anti-tumor immunity
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that two prebiotics, mucin and inulin, slowed the growth of melanoma in mice by boosting the immune system's ability to fight cancer. (2020-02-11)
Smartphone apps not accurate enough to spot all skin cancers
Smartphone apps that assess the risk of suspicious moles cannot be relied upon to detect all cases of skin cancer, finds a review of the evidence published by The BMJ today. (2020-02-10)
Research uncovers new path for melanoma detection and treatment
A new way to spot melanoma cells circulating in the blood has the potential to significantly improve the monitoring of cancer patients and guide future treatment. (2020-02-09)
Mayo researchers discover way to prime cancer tumors for immunotherapy
A cancer tumor's ability to mutate allows it to escape from chemotherapy and other attempts to kill it. (2020-02-07)
Do elevated mercury levels in the blood increase skin cancer risk?
Higher levels of mercury in the blood were linked with a higher prevalence of non-melanoma skin cancer, the most common human malignancy, in a study published in the British Journal of Dermatology. (2020-02-05)
Unprecedented exploration generates most comprehensive map of cancer genomes to date
An international team has completed the most comprehensive study of whole cancer genomes to date, significantly improving our fundamental understanding of cancer and signposting new directions for its diagnosis and treatment. (2020-02-05)
Study demonstrates liquid biopsy as effective predictor of stage III melanoma relapse and treatment
A study at The University of Texas MD Anderson Cancer Center showed that circulating tumor cells (CTCs), a form of liquid biopsy, was independently associated with melanoma relapse, suggesting CTC assessment may be useful in identifying patients at risk for relapse who could benefit from more aggressive therapy following primary treatment. (2020-02-03)
Cold plasma patch could make immunotherapy more effective for treating melanoma
An interdisciplinary team of researchers at the UCLA has developed a medicated patch that can deliver immune checkpoint inhibitors and cold plasma directly to tumors to help boost the immune response and kill cancer cells. (2020-02-03)
Shift in treatment modalities associated with improved outcomes in uveal melanoma patients with live
New retrospective study indicates that the shift of treatment from systemic chemotherapies to liver-directed therapies provides survival benefits. (2020-02-03)
Researchers identify possible new combination treatment for advanced melanoma
Immunotherapy drug in combination with an infusion of anti-tumor immune cells may produce a stronger immune response that could help fight advanced melanoma. (2020-01-31)
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