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Current Melanoma News and Events

Current Melanoma News and Events, Melanoma News Articles.
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New data on ctDNA as a biomarker for detecting cancer progression presented at ASCO
Scientists at the 2019 ASCO Annual Meeting presented research that relied on Droplet Digital PCR to explore the strengths and limitations of using circulating tumor DNA as a biomarker for predicting outcomes and guiding treatment for patients with cancer. (2019-07-11)
Moffitt researchers identify effective drug combination against uveal melanoma
Moffitt Cancer Center researchers have identified a new drug combination that is effective against metastatic uveal melanoma cells in preclinical studies. (2019-07-08)
FEFU scientists teamed up with colleagues to develop ointment for skin cancer prevention
Scientists from Far Eastern Federal University (FEFU), V.I. Vernadsky Crimean Federal University, Dmitry Mendeleev University of Chemical Technology, and Far Eastern Branch of the Russian Academy of Sciences (FEB RAS), assumed the risks of primary skin cancer and its recurrences can be significantly reduced by applying the ointment with antisense oligonucleotides which are short DNA, RNA fragments used in oncology to suppress the synthesis of tumor proteins. (2019-07-02)
Inexpensive equipment and training can improve melanoma detection and reduce biopsies
Researchers say non-dermatologist physicians can make earlier and more accurate diagnoses of melanomas using a dermatoscope. (2019-07-01)
Protein linked to aggressive skin cancer
Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer. (2019-06-28)
Does likelihood of survival differ between patients with single vs. multiple primary melanomas?
Patients with multiple primary melanomas had a higher likelihood of dying than those with a single primary melanoma in a study that used data from registries in the Netherlands. (2019-06-26)
Researchers identify compounds that starve melanoma cancer cells of energy
Researchers have found a possible counterpunch to the drug resistance of melanoma, the most dangerous form of skin cancer. (2019-06-18)
Tanning industry uses promos, cheap prices to lure adolescents and young adults
Everyone knows cigarette smoking causes cancer and as a result, prices and advertising are closely regulated to discourage youth from starting. (2019-06-17)
Sensitive, noninvasive platform detects circulating tumor cells in melanoma patients
Scientists have created a laser-based platform that can quickly and noninvasively screen large quantities of blood in patients with melanoma to detect circulating tumor cells (CTCs) -- a precursor to deadly metastases. (2019-06-12)
Determining risk of recurrence in triple-negative breast cancer
A personalized prognosis for patients diagnosed with triple-negative breast cancer was the goal of a new study by Katherine Varley, Ph.D., researcher at Huntsman Cancer Institute (HCI) and assistant professor of oncological sciences at the University of Utah. (2019-06-12)
Indoor tanning may be an addiction abetted by both genetic and psychiatric factors
A combination of elevated symptoms of depression along with modifications in a gene responsible for dopamine activity, important to the brain's pleasure and reward system, appear to influence an addiction to indoor tanning in young, white non-Hispanic women. (2019-06-11)
A molecular glue to overcome cancer drug resistance?
A team led by Duke researchers has discovered a small molecule drug that can stop cancer cells from becoming resistant to chemotherapy. (2019-06-07)
Three-drug combination helps curb the growth of deadly type of skin cancer
A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced melanoma. (2019-06-06)
Annual Report to the Nation: Overall cancer mortality continues to decline
For all cancer sites combined, cancer death rates continued to decline in men, women, and children in the United States from 1999 to 2016. (2019-05-30)
De-TOXing exhausted T cells may bolster CAR T immunotherapy against solid tumors
A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack. (2019-05-27)
Blood test can measure effectiveness of treatments for aggressive skin cancers
Blood tests that track the amount of tumor DNA can -- after only one month of drug therapy -- detect how well treatment is working in patients with skin cancer, a new study finds. (2019-05-15)
Five things to know about melanoma
'Five things to know about ... melanoma' in CMAJ (Canadian Medical Association Journal) provides a brief overview of this malignant skin cancer for physicians and patients. (2019-05-13)
Scientists grow precursors for human pigment cells
Our hair, skin and eyes are colored by a pigment called melanin, which is produced by pigment cells called melanocytes. (2019-05-09)
New computational tool enables powerful molecular analysis of biomedical tissue samples
Researchers at the Stanford University School of Medicine invented a computational technique called CIBERSORTx that can analyze the RNA of individual cells taken from whole-tissue samples or data sets. (2019-05-06)
Form drives function in cancer proliferation
A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress. (2019-05-06)
Elderly survivors of three common cancers face persistent risk of brain metastasis
Elderly survivors of breast cancer, lung cancer, and melanoma face risk of brain metastasis later in life, and may require extra surveillance in the years following initial cancer treatment. (2019-05-03)
Describing aspects of melanoma progression
Three related articles and an editorial focus on various aspects of melanoma progression. (2019-05-01)
Innovative treatment restores sight in patient
Innovative treatment has improved the vision of a patient suffering from a rare cancer-related syndrome affecting the eye, new research in the journal JAMA Ophthalmology reports. (2019-04-30)
Moffitt Researchers find BRAF protein modification could slow tumor growth
Researchers in Moffitt Cancer Center's Donald A. Adam Melanoma and Skin Cancer Center of Excellence have discovered a signaling pathway between cytokines and BRAF that promotes tumor growth. (2019-04-24)
Moffitt researchers identify mechanism of resistance to BRAF inhibitors in melanoma
Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. (2019-04-15)
CNIO researchers assess melanoma progression with a new liquid biopsy technique
Analysis of extracellular vesicles and circulating DNA from fluid obtained from the drainage implanted after surgery, normally disposed of as medical waste, detects melanoma patients with risk of recurrence and may help doctors decide who should undergo adjuvant therapy The new technique might change the way melanoma patients are followed up. (2019-04-11)
Cancer: Central role of cell 'skeleton' discovered
All cells possess a cytoskeleton which allows them to move and maintain their shape. (2019-04-10)
Researchers determine how a major tumor suppressor pathway becomes deactivated
The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans. (2019-04-04)
New formula better predicts speed of tumor growth in 12 cancers
University at Buffalo researchers have developed a new method to more accurately predict tumor growth rates, a crucial statistic used to schedule screenings and set dosing regimens in cancer treatment. (2019-04-03)
Gut microbiome directs the immune system to fight cancer
Researchers at Sanford Burnham Prebys have demonstrated a causal link between the gut microbiome and the immune system's ability to fight cancer. (2019-04-02)
Is your melanoma hot enough for immunotherapy?
University of Colorado Cancer Center study presented at AACR 2019 shows that tumors with mutations in genes leading to over-activation of the NF-kB signaling pathway were more than three times as likely to respond to anti-PD1 immunotherapy compared with tumors in which these changes were absent. (2019-04-02)
HDAC inhibition may combat resistance to anti-PD-1 therapy in patients with melanoma
A combination of the experimental histone deacetylase (HDAC) inhibitor entinostat with the anti-PD-1 therapeutic pembrolizumab (Keytruda) showed clinical responses in patients with melanoma that had progressed on prior anti-PD-1 treatment, according to results from the ENCORE 601 phase Ib/II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-01)
Heating up tumors could make CAR T therapy more effective, study finds
A preclinical study led by scientists at the UCLA Jonsson Comprehensive Cancer suggests that heating solid tumors during CAR T-cell therapy can enhance the treatment's success. (2019-03-27)
BU researchers discover therapeutic target of melanoma
Researchers have identified a biomarker and a possible new therapy for melanoma. (2019-03-25)
MD Anderson study may explain why immunotherapy not effective for some patients with metastatic melanoma and kidney cancer
White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. (2019-03-25)
Low-cost 'cancer probe' could spot deadly melanoma early
Work is being done at UBC on a tool to help in the early detection of melanoma: a simple, compact laser probe that can distinguish between harmless moles and cancerous ones -- in a matter of seconds. (2019-03-06)
Seawater bacteria provides leads to fight melanoma
Malignant melanoma can be a particularly dangerous form of cancer, and more therapeutic options are needed. (2019-03-06)
Nuclear medicine imaging monitors effectiveness of therapy for melanoma patients
Nuclear medicine imaging with PET/CT can monitor the effectiveness of immunotherapy treatment for metastatic melanoma and predict outcome. (2019-03-05)
Genomic testing of a single patient reveals a gene commonly mutated in pediatric melanoma
Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma. (2019-03-04)
Artificial intelligence could predict spread of melanoma
The BGU/ UTSW group demonstrated that their representation of the functional state of individual cells can predict the likelihood that a stage III melanoma, with malignancies limited to the lymphatic system, will progress to stage IV, in which the cancer has spread from the principal area to the rest of the patient's body. (2019-02-26)
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