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Current Mitochondria News and Events

Current Mitochondria News and Events, Mitochondria News Articles.
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Temple researchers identify new target regulating mitochondria during stress
Like an emergency response team that is called into action to save lives, stress response proteins in the heart are activated during a heart attack to help prevent cell death. (2019-09-19)
Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy
Wistar researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. (2019-09-19)
How to construct a protein factory
The complexity of molecular structures in the cell is amazing. (2019-09-19)
Study points to new drug target in fight against cancer
Rice University researchers are members of an international team that's discovered how a cancer-linked version of the protein mitoNEET can close voltage-dependent anion channels (VDAC), primary gateways in the outer surface of mitochondria. (2019-09-18)
Too much of a good thing: Overactive immune cells trigger inflammation
Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. (2019-09-16)
Type 2 diabetes is not just about insulin
Obesity, by promoting the resistance to the action of insulin, is a major risk factor of diabetes. (2019-09-11)
Scientists listed ways of applying genetic engineering to treat Parkinson's disease
Researchers of Sechenov University and University of Pittsburgh described the most promising strategies in applying genetic engineering for studying and treating Parkinson's disease. (2019-09-10)
High-fat diets affect your brain, not just your physical appearance
Much research has pointed to how an unhealthy diet correlates to obesity, but has not explored how diet can bring about neurological changes in the brain. (2019-09-09)
Discovered the potential of antihistamines that cause the death of leukaemic stem cells
The IJC Leukaemic Stem Cell research group, led by Ruth M. (2019-09-06)
Temple scientists identify promising new target to combat Alzheimer's disease
In the case of Alzheimer's disease, Temple researchers show that mitochondrial calcium transport remodeling -- what appears to be an attempt by cells to compensate for flagging energy production and metabolic dysfunction -- while initially beneficial, ultimately becomes maladaptive, fueling declines in mitochondrial function, memory, and learning. (2019-09-03)
Tiny thermometer measures how mitochondria heat up the cell by unleashing proton energy
Armed with a tiny new thermometer probe that can quickly measure temperature inside of a cell, University of Illinois researchers have illuminated a mysterious aspect of metabolism: heat generation. (2019-08-29)
High-end microscopy reveals structure and function of crucial metabolic enzyme
The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. (2019-08-28)
Cell biology -- Potential drop signals imminent danger
Misfolded proteins must be promptly eliminated as they can form toxic aggregates in cells. (2019-08-28)
Runaway mitochondria cause telomere damage in cells
Targeted damage to mitochondria produces a 'Chernobyl effect' inside cells, pelting the nucleus with harmful reactive oxygen species and causing chromosomal damage. (2019-08-26)
What drives inflammation in type 2 diabetes? Not glucose, says new research
Research led by Barbara Nikolajczyk, Ph.D., disproved the conventional wisdom that glucose was the primary driver of chronic inflammation in type 2 diabetes. (2019-08-21)
New clues on stem cell transplant rejection revealed in study
'The role of mitochondria has been largely ignored in the field of regenerative medicine, but earlier efforts in our lab suggested that they may affect the outcome of stem cell transplants,' said Tobias Deuse, M.D., the Julien I.E. (2019-08-19)
Cell biology: Compartments and complexity
Ludwig-Maximilians-Universitaet (LMU) in Munich biologists have taken a closer look at the subcellular distribution of proteins and metabolic intermediates in a model plant. (2019-08-13)
Live mitochondria seen in unprecedented detail: Photobleaching in STED microscopy overcome
A research team led by Nagoya University has created a fluorescent marker molecule that does not degrade under a STED microscope: the photobleaching problem has been solved. (2019-08-08)
Deregulated mTOR is responsible for autophagy defects exacerbating kidney stone formation
Kidney stone disease is a lifestyle-related disease prevalent; however, effective medical treatment for the disease is not yet well established. (2019-08-06)
Low level exposure to air pollution is harmful, mouse model shows
Scientists investigating the effect of air pollution on lung health, in an animal model, have concluded that even low levels of exposure can have a detrimental effect on the lungs. (2019-08-01)
Detox pathway extends lifespan of the worm C. elegans
Mutation in mitochondrial gene doubles the lifespan in the worm C. elegans by turning on a detox pathway, researchers of the Cluster of Excellence CECAD report in Nature Communications. (2019-07-25)
Differences in MS patients' cerebrospinal fluid may be key to drugs that halt progression
Effective therapies exist for managing relapsing/remitting MS, but treatment for progressive MS has proved more challenging. (2019-07-15)
Biocompound from Atlantic Rainforest combats leishmaniasis and Chagas disease
Researchers find that substances synthesized from plant species endemic to the biodiversity hotspot can kill the parasites that cause these neglected diseases. (2019-07-15)
Keeping a cell's powerhouse in shape
A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. (2019-07-10)
Researchers can finally modify plant mitochondrial DNA
Researchers in Japan have edited plant mitochondrial DNA for the first time, which could lead to a more secure food supply. (2019-07-08)
UTA researchers identify genetic pathway that could enhance survival of coral
Three researchers at The University of Texas at Arlington have made a groundbreaking discovery that could enhance the ability of reef-building corals to survive a rapidly warming and disease-filled ocean. (2019-07-08)
Caspase-1 initiates apoptosis, but not pyroptosis, in the absence of gasdermin D
Caspase-1 triggers programmed necrosis called pyroptosis by gasdermin-D (GSDMD) cleavage. (2019-07-05)
WVU researchers map crystals to advance treatments for stroke, diabetes, dementia
A team of WVU researchers -- including Werner Geldenhuys, John Hollander and Aaron Robart--have mapped the crystal structure of a protein called 'mitoNEET' and pinpointed how a drug latches on it. (2019-07-03)
Cancer cell's 'self eating' tactic may be its weakness
Researchers reveal how pancreatic cancer cells adapt to the low energy environment of a tumor: by eating their own mitochondria! (2019-07-01)
Study finds electronic cigarettes damage brain stem cells
A research team at the University of California, Riverside, has found that electronic cigarettes, often targeted to youth and pregnant women, produce a stress response in neural stem cells, which are critical cells in the brain. (2019-07-01)
Study: Phenols in cocoa bean shells may reverse obesity-related problems in mouse cells
A new study by researchers at the University of Illinois suggests that three of the phenolic compounds in cocoa bean shells have powerful effects on the fat and immune cells in mice, potentially reversing the chronic inflammation and insulin resistance associated with obesity. (2019-06-20)
SPbU scientists have discovered the first family of extracellular Rickettsia-like bacteria
Microbiologists of St Petersburg University, together with researchers from the University of Milan, the University of Pisa, and the University of Pavia, have discovered a new family of bacteria belonging to the order Rickettsiales -- Deianiraeaceae. (2019-06-14)
SIRT1 plays key role in chronic myeloid leukemia to aid persistence of leukemic stem cells
Patients with chronic myeloid leukemia are treated with tyrosine kinase inhibitors. (2019-06-10)
Worm study sparks hope for slowing muscle decline
Muscle decline caused by ageing and certain diseases could be dramatically slowed by stopping a chain reaction that damages cells, new research shows. (2019-06-07)
Astrocytes protect neurons from toxic buildup
Neurons off-load toxic by-products to astrocytes, which process and recycle them. (2019-05-31)
Circadian clock and fat metabolism linked through newly discovered mechanism
Princeton University researchers found that the enzyme Nocturnin, known for its role in fat metabolism and circadian rhythm, acts on two well-established molecules in metabolism. (2019-05-30)
Dissolving protein traffic jam at the entrance of mitochondria
Researchers from Freiburg discovered a novel mechanism that ensures obstacle-free protein traffic into the powerhouse of the cell. (2019-05-23)
Interplay between mitochondria and nucleus may have implications for new treatment
Mitochondria, the 'batteries' that produce our energy, interact with the cell's nucleus in subtle ways previously unseen in humans, according to research published today in the journal Science. (2019-05-23)
Researchers link new protein to Parkinson's
Cells depend on a protein called Parkin, which is mutated in some forms of Parkinson's disease, to get rid of damaged mitochondria. (2019-05-20)
Miro2 is a Parkin receptor for selective removal of damaged mitochondria
Defects in mitophagy are linked to a variety of human diseases including Parkinson's and cardiac disorders. (2019-05-16)
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