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Current Mitochondria News and Events

Current Mitochondria News and Events, Mitochondria News Articles.
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Repair instead of renew: Damaged powerhouses of cells have their own 'workshop mode'
CECAD-researchers find a molecular repair pathway for cellular energy production, publication in 'Nature Communications' (2020-04-02)
Exeter researchers discover a novel chemistry to protect our crops from fungal disease
Exeter researchers have discovered a novel chemistry to protect our crops from fungal disease. (2020-03-30)
New mechanism underlying organelle communication revealed in brown fat cells
A new study reveals an underappreciated interplay between the endoplasmic reticulum and the mitochondria with implications for weight loss and disease. (2020-03-30)
How trans fats assist cell death
Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases. (2020-03-25)
UCI team demonstrates ability to supercharge cells with mitochondrial transplantation
UCI researchers have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. (2020-03-23)
New research may help older adults stay physically capable for longer
Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria. (2020-03-22)
Antioxidant treatment in acute ischemic stroke may delay the onset of Alzheimer's dementia
There is a considerable overlap between vascular risk factors and risk factors of Alzheimer's disease (AD). (2020-03-17)
Cell biology -- maintaining mitochondrial resilience
Mitochondria cannot autonomously cope with stress and must instead call on the cell for help. (2020-03-09)
Yale researchers help restore hormonal balance disrupted in metabolic diseases
Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver. (2020-03-04)
Boosting energy levels within damaged nerves may help them heal
When the spinal cord is injured, the damaged nerve fibers -- called axons -- are normally incapable of regrowth, leading to permanent loss of function. (2020-03-03)
Blocking energy production in immune cells helps tumours escape treatment
A small molecule that inhibits energy production in immune T-cells allows some tumours to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife. (2020-03-03)
IU scientists study link between energy levels, spinal cord injury
A team of researchers from Indiana University School of Medicine, in collaboration with the National Institute of Neurological Disorders and Stroke, have investigated how boosting energy levels within damaged nerve fibers or axons may represent a novel therapeutic direction for axonal regeneration and functional recovery. (2020-03-03)
Mayo Clinic researchers clarify how cells defend themselves from viruses
A protein known to help cells defend against infection also regulates the form and function of mitochondria, according to a new paper in Nature Communications. (2020-03-03)
Oncotarget | SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism
Oncotarget Volume 11 Issue 8 reported that while it is known that cancer cells require one-carbon and FAD-dependent mitochondrial metabolism to sustain cell proliferation, the role of SLC25A32 in cancer cell growth remains unexplored. (2020-02-28)
Scientists find link between genes and ability to exercise
A team of researchers have discovered a genetic mutation that reduces a patient's ability to exercise efficiently. (2020-02-26)
Study detects abnormally low levels of a key protein in brains of young men with autism
Brains of young men with autism spectrum disorder (ASD) have low levels of a protein that appears to play a role in inflammation and metabolism. (2020-02-21)
Changing what heart cells eat could help them regenerate
Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die. (2020-02-21)
A deep dive into cellular aging
Scientists at Sanford Burnham Prebys and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell's nucleus--and identified an FDA-approved drug that helped suppress the damaging effects of the condition in cells and mice. (2020-02-20)
This study shows how a lack of oxygen during pregnancy can cause schizophrenia
Experiments with rats indicate that brain cells submitted to several forms of hypoxia underwent alterations to their energy production mechanism. (2020-02-20)
A new model of the worm C. elegans to progress in the study of a rare disease
he IDIBELL Neurometabolic Diseases group, with international collaboration, has identified a model of chromosome X-linked adrenoleukodystrophy (x-ALD) in the earthworm C. elegans, this is a rare disorder of the nervous system with no treatment available. (2020-02-19)
Unexpected insights into the dynamic structure of mitochondria
As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. (2020-02-18)
Targeting turncoat immune cells to treat cancer
A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor. (2020-02-18)
SR-FACT microscopy reveals the landscape of the cellular organelle interactome
We developed super-resolution fluorescence-assisted diffraction computational tomography(SR-FACT), which combines three-dimensional optical diffraction tomography with two-dimensional fluorescence Hessian structured illumination microscopy. (2020-02-17)
X-ray microscopy at BESSY II: Nanoparticles can change cells
Nanoparticles easily enter into cells. New insights about how they are distributed and what they do there are shown for the first time by high-resolution 3D microscopy images from BESSY II. (2020-02-12)
Parkinson's and the immune system
Mutations in the Parkin gene are a common cause of hereditary forms of Parkinson's disease. (2020-02-05)
Study provides new understanding of mitochondria genome with potential for new avenues of treatment for multiple cancers
A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the 'powerhouse of the cell.' Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis. (2020-02-05)
Structural biology: Special delivery
Bulky globular proteins require specialized transport systems for insertion into membranes. (2020-02-03)
Disease-aggravating mutation found in a mouse model of neonatal mitochondrial disease
The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. (2020-01-29)
Biophysicists find 'extra' component in molecular motor
Researchers discovered an additional component in ATP synthase, a molecular machine that produces the energy-conserving compound. (2020-01-29)
Consequences of Zika virus attack on glial cells
Few studies have identified the effects of zika virus infection on astrocytes, as well as their association with developmental alterations, including brain malformations and microcephaly. (2020-01-27)
A new blood component revealed
Does the blood we thought to know so well contain elements that had been undetectable until now? (2020-01-23)
Immune cell health discovery could optimise cancer therapies
Scientists at UCL have discovered how immune cells, essential for tackling life-threatening infections and cancers, are able to 'recycle' material within themselves in order to stay healthy and function, a breakthrough finding which could lead to more effective immunotherapies. (2020-01-21)
Zebrafish teach researchers more about atrial fibrillation
Genetic research in zebrafish at the University of Copenhagen has surprised the researchers behind the study. (2020-01-21)
Experimental therapy may offer hope for rare genetic disorders
Researchers at Massachusetts General Hospital (MGH) have developed a new way to alleviate problems caused by dysfunctional mitochondria, which are the ''powerhouses'' that produce energy in cells (2020-01-13)
Protein associated with ovarian cancer exacerbates neurodegeneration in Alzheimer's
Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer's disease, by combining computational methods and lab research. (2020-01-12)
Neurons' energy organelle protected from damage linked to ALS, Alzheimer's
Mitochondrial damage is increasingly recognized as a key factor underlying neurodegenerative diseases including Alzheimer's, Parkinson's, and ALS. (2020-01-08)
MDI biological scientists identify pathways that extend lifespan by 500%
Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. (2020-01-08)
Researchers suggest a pathway to reverse the genetic defect of Friedreich's ataxia
Scientists have identified a molecular mechanism that could reverse the genetic defect responsible for Friedreich's ataxia, a neurodegenerative disease that leaves its victims with difficulty walking, a loss of sensation in the arms and legs and impaired speech. (2020-01-06)
New insights into the earliest events of seed germination
Plant seeds can store their energy in a dry state for years, only to suddenly release it and germinate. (2019-12-27)
Evolution: Revelatory relationship
A new study of the ecology of an enigmatic group of novel unicellular organisms by scientists from Ludwig-Maximilians-Universitaet (LMU) in Munich supports the idea hydrogen played an important role in the evolution of Eukaryota, the first nucleated cells. (2019-12-27)
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