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Current Mitochondria News and Events, Mitochondria News Articles.
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OPTN-ATG9 interaction accelerates autophagic degradation of ubiquitin-labeled mitochondria
Damaged mitochondria are selectively eliminated via autophagy (called mitophagy). Parkin and PINK1, proteins mutated in hereditary Parkinson's disease, amplify ubiquitin signals on damaged mitochondria with the subsequent activation of autophagic machinery. (2020-07-09)
Biologists trace plants' steady mitochondrial genomes to a gene found in viruses, bacteria
CSU biologists have traced the stability of plant mitochondrial genomes to a particular gene - MSH1 - that plants have but animals don't. (2020-07-09)
Researchers find promising therapy to fight epidemic of liver disease
In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in preclinical mouse models, according to researchers at the University of Colorado Anschutz Medical Campus. (2020-07-08)
Evolutionary biologists find several fish adapt in the same way to toxic water
Several species of fish have adapted to harsh environments using the same mechanism, which brings to question evolutionary chance, according to a study by Kansas State University and Washington State University. (2020-07-08)
How to precisely edit mitochondrial DNA
A gene editing tool based on a bacterial toxin can make precise changes to mitochondrial DNA inside cells. (2020-07-08)
Star-shaped brain cells shed light on the link between cannabis use and sociability
Cannabis use can lead to behavioral changes, including reduced social interactions in some individuals. (2020-07-08)
New molecular tool precisely edits mitochondrial DNA
The precision editing technologies that have revolutionized DNA editing in the cell nucleus have been unable to reach the mitochondrial genome. (2020-07-08)
New link between calcium and cardiolipin in heart defects
To function properly, the heart needs energy from cells' powerhouses, the mitochondria. (2020-07-07)
New vitamin K-based drug shows promise against medication-resistant epilepsy
Medical University of South Carolina researchers have designed a new vitamin K-based compound that shows excellent seizure-control properties, even in preclinical models of medication-resistant seizures. (2020-07-06)
Toxic air pollution nanoparticles found in heart cell 'powerhouses' of city dwellers
Toxic metallic air pollution nanoparticles are getting inside the crucial, energy-producing structures within the hearts of people living in polluted cities, causing cardiac stress -- a new study confirms. (2020-07-03)
Moss protein corrects genetic defects of other plants
Almost all land plants employ an army of molecular editors who correct errors in their genetic information. (2020-07-02)
Revisiting energy flow in photosynthetic plant cells
By developing innovative methods to visualize energy changes in subcellular compartments in live plants, the team of Dr Boon Leong LIM, Associate Professor of the School of Biological Sciences of The University of Hong Kong, recently solved a controversial question in photosynthesis: what is the source of NADH (Reduced Nicotinamide adenine dinucleotide) for mitochondria to generate ATP (Adenosine triphosphate)? (2020-06-30)
Power outage: Research offers hint about heart weakness in Barth syndrome
Researchers at UT Health San Antonio and collaborating institutions have found a clue about the processes that underlie Barth syndrome, a rare but devastating condition that features heart weakness. (2020-06-29)
Declining eyesight improved by looking at deep red light
Staring at a deep red light for three minutes a day can significantly improve declining eyesight, finds a new UCL-led study, the first of its kind in humans. (2020-06-28)
First successful delivery of mitochondria to liver cells in animals
This experiment marks the first time researchers have ever successfully introduced mitochondria into specific cells in living animals. (2020-06-25)
Quantifying the building blocks of DNA is now easier thanks to a novel technique
A highly sensitive and easy-to-use technique applicable for tissue samples can be useful, for example, to researchers specialised in mitochondrial diseases and cancer. (2020-06-24)
USC-led study: Protein in mitochondria appears to regulate health and longevity
A new study led by researchers at the USC Leonard Davis School of Gerontology is the first to demonstrate that a tiny protein, humanin, has a big impact on health and longevity in both animals and humans (2020-06-24)
Cyclosporin study may lead to novel ways of approaching mitochondrial dysfunction
Fungi producing cyclosporins exist as two reproducing stages: asexual -- soil fungi from which cyclosporin was initially extracted, and sexual -- parasitic fungi close to a popularly known genus Cordyceps. (2020-06-18)
New technique may quickly and accurately predict effective therapies in solid tumors
A new method of screening thousands of drugs in freshly collected human tumor cells can help identify which of the drugs are most likely to be effective against those cancers. (2020-06-16)
Exposure to air pollution impairs cellular energy metabolism
Exposure to air particulate matter impairs the metabolism of olfactory mucosal cells, according to a recent study from the University of Eastern Finland. (2020-06-15)
Lack of mitochondria causes severe disease in children
Researchers at Karolinska Institutet in Sweden have discovered that excessive degradation of the power plants of our cells plays an important role in the onset of mitochondrial disease in children. (2020-06-11)
Study discovers BAM15 as a potential treatment for obesity
A new study offers the first evidence that a protein named BAM15 acts as an energy uncoupler and could be an effective drug for treating obesity and related diseases. (2020-06-10)
Drug researcher develops 'fat burning' molecule
Santos and his colleagues have recently identified a small mitochondrial uncoupler, named BAM15, that decreases the body fat mass of mice without affecting food intake and muscle mass or increasing body temperature (2020-06-08)
Discovery of proteins that regulate interorganelle communication
This groundbreaking discovery of the key factor in the formation of MAM is expected to contribute to research on Neurodegenerative Diseases. (2020-06-02)
Temple researchers track new path to therapeutic prevention of abdominal aortic aneurysm
New research by scientists at the Lewis Katz School of Medicine at Temple University suggests that abdominal aortic aneurysm (AAA) can be prevented therapeutically. (2020-05-28)
Subcellular chatter regulates longevity
As people get older, they often feel less energetic, mobile or active. (2020-05-19)
General descriptor sparks advancements in dye chemistry
SUTD collaborates with international researchers to move away from inefficient trial-and-error developments in dye chemistry and quantitatively design luminescent materials. (2020-05-14)
High calcium levels in mitochondria linked to neuronal death in Alzheimer's disease
For the first time, using a mouse model of Alzheimer's disease, scientists at Massachusetts General Hospital have documented a link between raised levels of calcium in mitochondria and neuronal death in the living brain. (2020-05-12)
Temple finds link between blood vessel inflammation, malfunctioning cellular powerhouses
In new research, scientists at the Lewis Katz School of Medicine at Temple University have uncovered a novel mechanism by which abnormalities in mitochondrial fission in endothelial cells contribute to inflammation and oxidative stress in the cardiovascular system. (2020-05-11)
First simulation of a full-sized mitochondrial membrane
Scientists from the University of Groningen have developed a method that combines different resolution levels in a computer simulation of biological membranes. (2020-05-08)
New molecular auto-control system to avoid an excessive brown adipose tissue activity
A scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes. (2020-05-07)
For ME/CFS patients, viral immunities come at a devastating, lifelong cost
Researchers at UC San Diego School of Medicine and three German universities describe an underlying biological basis for myalgic encephalomyelitis/chronic fatigue syndrome, illustrating how efforts by the body to boost immune system protections can come at physiological cost elsewhere. (2020-04-27)
Study reveals importance of mitochondrial small proteins in energy production
A small mitochondrial protein is necessary for energy production and its malfunction could be behind a range of degenerative diseases, according to study by Duke-NUS Medical School and their collaborators. (2020-04-16)
Study finds evidence for existence of elusive 'metabolon'
For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or 'metabolons,' in facilitating various processes within cells. (2020-04-16)
Crohn's disease: Preserving inflammation-free phases
Crohn's disease is a chronic inflammatory disorder of the intestine that, in most cases, relapses episodically. (2020-04-15)
New research insights into how a group of novel organelle-based disorders affects cells
A pioneering study has shed new light on how a group of novel organelle-based disorders affect cells. (2020-04-09)
Repair instead of renew: Damaged powerhouses of cells have their own 'workshop mode'
CECAD-researchers find a molecular repair pathway for cellular energy production, publication in 'Nature Communications' (2020-04-02)
Exeter researchers discover a novel chemistry to protect our crops from fungal disease
Exeter researchers have discovered a novel chemistry to protect our crops from fungal disease. (2020-03-30)
New mechanism underlying organelle communication revealed in brown fat cells
A new study reveals an underappreciated interplay between the endoplasmic reticulum and the mitochondria with implications for weight loss and disease. (2020-03-30)
How trans fats assist cell death
Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases. (2020-03-25)
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