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Current Mitochondria News and Events

Current Mitochondria News and Events, Mitochondria News Articles.
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Raising plants to withstand climate change
Success with improving a model plant's response to harsh conditions is leading plant molecular researchers to move to food crops including wheat, barley, rice and chickpeas. (2019-12-03)
TU Dresden biologists examine sperm quality on the basis of their metabolism
Every tenth couple worldwide is affected by infertility. The reasons for this are manifold, but mostly well researched. (2019-11-28)
The molecule that can AUTAC bad proteins
Tohoku University researchers have developed a strategy that could help cells get rid of disease-related debris. (2019-11-27)
Gene discovery in fruit flies could help search for new treatments for mitochondrial disease
Scientists have identified a protein in fruit flies that can be targeted to reverse the effects of disease-causing mutations in mitochondrial genes. (2019-11-27)
Mapping the pathway to gut health in HIV and SIV infections
A UC Davis study found that Lactobacillus plantarum bacteria rapidly repaired damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus. (2019-11-19)
Master regulator in mitochondria is critical for muscle function and repair
New study identifies how loss of mitochondrial protein MICU1 disrupts calcium balance and causes muscle atrophy and weakness. (2019-11-14)
Research points to possible target to treat idiopathic pulmonary fibrosis, or IPF
In a study of idiopathic pulmonary fibrosis, or IPF, recruited monocyte-derived macrophages with increased flux in their mevalonate pathway were able induce lung fibrosis in a mouse model without prior lung injury. (2019-11-12)
Oxygen deficiency rewires mitochondria
Researchers slow the growth of pancreatic tumor cells. (2019-11-11)
The pathway to Parkinson's takes a surprising twist
A new study finds that neurons affected in Parkinson's disease can shut down without fully dying, allowing them to also switch off neighboring cells. (2019-11-11)
Salmonella -- how the body fights back
New research shows how our immune system fights back against Salmonella infection. (2019-11-11)
Self-cannibalizing mitochondria may set the stage for ALS development
Northwestern Medicine scientists have discovered a new phenomenon in the brain that could explain the development of early stages of neurodegeneration that is seen in diseases such as ALS, which affects voluntary muscle movement such as walking and talking.  The discovery was so novel, the scientists needed to coin a new term to describe it: mitoautophagy, a collection of self-destructive mitochondria in diseased upper motor neurons of the brain that begin to disintegrate from within at a very early age. (2019-11-07)
SDHI pesticides are toxic for human cells
French scientists led by a CNRS researcher have just revealed that eight succinate dehydrogenase inhibitor pesticide molecules do not just inhibit the SDH activity of fungi, but can also block that of earthworms, bees, and human cells in varying proportions. (2019-11-07)
'Big data' for life sciences
Scientists have produced a co-regulation map of the human proteome, which was able to capture relationships between proteins that do not physically interact or co-localize. (2019-11-05)
New research tool for studying mitochondrial disorders and aging
Researchers at Karolinska Institutet in Sweden have developed a new research tool for studying how mitochondrial protein synthesis is affected by disease, pharmaceuticals, ageing and different physiological situations such as exercise and diet. (2019-11-05)
Molecular gatekeepers that regulate calcium ions key to muscle function
Controlled entry of calcium ions into the mitochondria, the cell's energy powerhouses, makes the difference between whether muscles grow strong or easily tire and perish from injury, according to research published in Cell Reports. (2019-10-31)
Cocktail proves toxic to leukemia cells
Rice bioscientists find a way to predict the sensitivity of acute myeloid leukemia to mitochondria-damaging molecules and develop cocktails to fight the cancer. (2019-10-31)
Mitochondrial activity in lung tumors predicts response to drug inhibitor
Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new biomarker using a noninvasive imaging method that tracks mitochondrial activity in lung tumors. (2019-10-30)
Mysterious microproteins have major implications for human disease
As the tools to study biology improve, researchers are beginning to uncover details into microproteins, small components that appear to be key to some cellular processes. (2019-10-25)
Health in old age is a lifelong affair
Reduced food intake in old mice can no longer improve health. (2019-10-23)
Newly discovered protein is the permit to the powerhouse of cells
Medical University of South Carolina (MUSC) researchers report in Science Advances the discovery of a protein, P17/PERMIT, that is key to recycling aging and damaged mitochondria. (2019-10-23)
A compound effective to chemotherapy-resistant cancer cells identified
A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity. (2019-10-18)
Stress in the powerhouse of the cell
University of Freiburg researchers discover a new principle -- how cells protect themselves from mitochondrial defects. (2019-10-18)
Failure of mitochondrial quality control causes heart disease
Mutations in the gene that encodes a protein called ANT cause a variety of conditions, such as heart disease, but the underlying mechanism of how these mutations trigger disease has been unclear. (2019-10-16)
Coffee bean extracts alleviate inflammation, insulin resistance in mouse cells
Food science and human nutrition researchers at the University of Illinois are interested in the potential of inflammation-fighting compounds found in the silverskin and husk of coffee beans, not only for their benefits in alleviating chronic disease, but also in adding value to would-be 'waste' products from the coffee processing industry. (2019-10-11)
Maternal obesity speeds up aging in offspring
The effects of maternal obesity even pass across generations to offspring, accelerating the rate of aging of metabolic problems that occur in normal life. (2019-10-10)
Uncovering the presynaptic distribution and profile of mitochondria
In a recent study published in the Journal of Neuroscience, scientists from the MPFI and the University of Iowa CCOM have provided unprecedented insight into the presynaptic distribution and profile of mitochondria in the developing and mature calyx of Held. (2019-10-09)
New study challenges our understanding of premature ageing
Disturbances in the function of mitochondrial DNA can accelerate the ageing process in ways that are different than previously thought, according to a new Finnish study published in Nature Metabolism. (2019-10-08)
Maternal obesity hastens offspring aging, increasing diabetes & heart disease likelihood
New research in The Journal of Physiology has shown that the effects of maternal obesity even pass across generations to offspring, accelerating the rate of aging of metabolic problems that occur in normal life. (2019-10-08)
CNIC scientists discover a new mechanism for the transfer of maternal genetic material
CNIC researchers have identified a mechanism involved in the prevention of possible errors during the transfer of mitochondrial DNA from mothers to their offspring. (2019-10-03)
High-fructose and high-fat diet damages liver mitochondria, study finds
High levels of fructose in the diet inhibit the liver's ability to properly metabolize fat. (2019-10-01)
Stanford scientists find potential diagnostic tool, treatment for Parkinson's disease
Investigators at the Stanford University School of Medicine have pinpointed a molecular defect that seems almost universal among patients with Parkinson's disease and those at a high risk of acquiring it. (2019-09-26)
Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth
A new discovery about pancreatic cancer sheds light on how the cancer fuels its growth and may help explain how promising cancer drugs work -- and for whom they will fail. (2019-09-26)
Anxiety disorders linked to disturbances in the cells' powerhouses
The powerhouse of the cell, the mitochondria, provides energy for cellular functions. (2019-09-26)
Why the lettuce mitochondrial genome is like a chopped salad
The genomes of mitochondria are usually depicted as rings or circles. (2019-09-20)
Temple researchers identify new target regulating mitochondria during stress
Like an emergency response team that is called into action to save lives, stress response proteins in the heart are activated during a heart attack to help prevent cell death. (2019-09-19)
Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy
Wistar researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. (2019-09-19)
How to construct a protein factory
The complexity of molecular structures in the cell is amazing. (2019-09-19)
Study points to new drug target in fight against cancer
Rice University researchers are members of an international team that's discovered how a cancer-linked version of the protein mitoNEET can close voltage-dependent anion channels (VDAC), primary gateways in the outer surface of mitochondria. (2019-09-18)
Too much of a good thing: Overactive immune cells trigger inflammation
Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. (2019-09-16)
Type 2 diabetes is not just about insulin
Obesity, by promoting the resistance to the action of insulin, is a major risk factor of diabetes. (2019-09-11)
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