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Current Neurodegenerative diseases News and Events

Current Neurodegenerative diseases News and Events, Neurodegenerative diseases News Articles.
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NIAID scientists develop 'mini-brain' model of human prion disease
Scientists have used human skin cells to create what they believe is the first cerebral organoid system, or 'mini-brain,' for studying sporadic Creutzfeldt-Jakob disease (CJD). (2019-06-14)
How the cell protects itself
The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. (2019-06-12)
Researchers discover potential new therapeutic target for Alzheimer's disease
Apolipoproten E (apoeE) is a major genetic risk factor for the development of Alzheimer's disease, yet it tends to be understudied as a potential druggable target for the mind-robbing neurodegenerative disease. (2019-06-12)
Breaking down pathological protein aggregates
ETH researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. (2019-06-06)
Ultrasound method restores dopaminergic pathway in brain at Parkinson's early stages
Researchers have developed a technique that could open up new ways to facilitate targeted drug delivery into the brain, enabling drugs to treat brain diseases more focally. (2019-06-06)
Searching for the origins of the depressive symptoms in Huntington's disease
About 40% of the affected patients with Huntington's disease -- a neurodegenerative pathology -- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease. (2019-05-31)
Raw or cooked: this is how we recognise food
Do we see an apple? The occipital cortex in our brain will activate itself to recognise it. (2019-05-30)
Analyzing a protein from the cerebrospinal fluid will help diagnose patients with prion diseases
Recently, a study published in the Journal of Neurology, Neurosurgery & Psychiatry demonstrates that very high levels of neurogranin in the cerebrospinal fluid can be detected in human patients that suffer from prion diseases. (2019-05-29)
Newly discovered mechanism reveals how Parkinson's disease can spread between brain cells
Tiny channels between nerve cells are involved in a newly discovered mechanism of how Parkinson's disease can spread throughout the brain, according to new research from Linköping University, Sweden. (2019-05-28)
Coat of proteins makes viruses more infectious and links them to Alzheimer's disease
New research from Stockholm University and Karolinska Institutet shows that viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface. (2019-05-27)
Broken brain cells repaired in dementia mouse model
Dysfunctional neurons in the hippocampus of adult female mice modeling dementia can be repaired and reconnected to distant parts of the brain, reports a new study published in JNeurosci. (2019-05-27)
Study analyzes mortality risks among pro athletes
A first-of-its-kind comparison between elite pro athletes suggests higher overall mortality among NFL players compared with MLB players. (2019-05-24)
Dissolving protein traffic jam at the entrance of mitochondria
Researchers from Freiburg discovered a novel mechanism that ensures obstacle-free protein traffic into the powerhouse of the cell. (2019-05-23)
Shedding light on cancer metabolism in real-time with bioluminescence
Cancerous tumors can be made to bioluminesce, like fireflies, according to the level of their glucose uptake, giving rise to a technique for quantifying metabolite absorption. (2019-05-20)
Miro2 is a Parkin receptor for selective removal of damaged mitochondria
Defects in mitophagy are linked to a variety of human diseases including Parkinson's and cardiac disorders. (2019-05-16)
How mutations lead to neurodegenerative disease
Scientists have discovered how mutations in DNA can cause neurodegenerative disease. (2019-05-13)
Detecting dementia's damaging effects before it's too late
Patients with a rare neurodegenerative brain disorder called Primary Progressive Aphasia, or PPA, show abnormalities in brain function in areas that look structurally normal on an MRI scan. (2019-05-13)
Stem cells provide information about neuron resilience in ALS
Researchers at Karolinska Institutet in Sweden have developed a stem cell based model in order to study the resilience and vulnerability of neurons in the neurodegenerative disease ALS. (2019-05-09)
Serotonin boosts neuronal powerplants protecting against stress
Research from the Vaidya and Kolthur-Seetharam groups (TIFR) shows that the neurotransmitter serotonin enhances the production and functions of neuronal mitochondria, the powerhouse of the cell, and protect against stress. (2019-05-09)
Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders
Our brains do not only contain neurons, but also a variety of immune cells that play an important role for its functioning. (2019-05-06)
Pigment-producing stem cells can regenerate vital part of nervous system
Neurodegenerative diseases like multiple sclerosis (MS) affect millions of people worldwide and occur when parts of the nervous system lose function over time. (2019-05-06)
New chemical probe for visualizing brain immune cells
Researchers in South Korea and Singapore have, for the first time, developed a chemical probe that enables live-imaging of a type of immune cells in the brain, known as microglia, in a live animal brain. (2019-05-02)
Alzheimer's disease is a 'double-prion disorder,' study shows
Two proteins central to the pathology of Alzheimer's disease act as prions -- misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape -- according to new UC San Francisco research. (2019-05-01)
NeurExo Sciences and Henry Ford present preclinical data on exposomes at ISEV2019
NeurExo Sciences, LLC and Henry Ford Health System today announced the presentation of new data on exosomes at the International Society for Extracellular Vesicles (ISEV) 2019 Annual Meeting being held April 24-28, 2019 in Kyoto, Japan. (2019-04-26)
Proteins stand up to nerve cell regression
Fruit fly studies reveal proteins that promote healthy nervous system development by preventing the reversal of nerve cell differentiation. (2019-04-24)
New synthesis strategy speeds identification of simpler versions of a natural product
A new chemical synthesis strategy to harvest the rich information found in natural products -- organic compounds isolated from natural sources -- has led to the identification of novel, simpler derivatives with potential to selectively protect neurons, important for neurodegenerative diseases like Alzheimer's disease, or to prevent the immune system from rejecting organ transplants, a Baylor-led study finds (2019-04-24)
More evidence that blood tests can detect the risk of Alzheimer's
A new study confirms that a simple blood test can reveal whether there is accelerating nerve cell damage in the brain. (2019-04-23)
How fish brain cells react to Alzheimer's disease
Researchers in Dresden, Germany, have studied the regenerative capacity of zebrafish brain in single cell resolution with the aim of developing novel strategies against Alzheimer's. (2019-04-23)
How the body protects itself from type 2 diabetes
A specific group of white blood cells, termed 'regulatory T cells', keeps the immune system in balance and suppresses its activity to protect the body against autoimmune diseases. (2019-04-23)
Blood pressure drug shows promise for treating Parkinson's and dementia in animal study
A prescribed drug to treat high blood pressure has shown promise against conditions such as Parkinson's, Huntington's and forms of dementia in studies carried out in mice and zebrafish at the University of Cambridge. (2019-04-18)
Studies identify mechanism key to removal of protein aggregates from cells
Massachusetts General Hospital investigators have discovered the mechanism by which cells sense dysfunction of the proteasome -- a cellular component that degrades unneeded or defective proteins -- and respond in a previously undescribed manner, by editing the amino acid sequence of a key sensing protein. (2019-04-18)
Barrow researcher discovers critical RNA processing aberrations
Research by a Barrow Neurological Center scientist on mechanisms of dysfunctional RNA processing in ALS and frontaltemporal dementia (FTD) was published in the April issue of Acta Neuropathologica. (2019-04-18)
What happens in the bodies of ALS patients?
Lara Marrone and Jared Sterneckert from the Centre for Regenerative Therapies Dresden (CRTD) at Technische Universität Dresden (TUD), together with collaborating scientists from Germany, Italy, the Netherlands, and the USA, have now discovered that interactions between RNA-binding proteins are more critical to ALS pathogenesis than previously thought. (2019-04-15)
Protein complex may help prevent neurodegenerative diseases
The protein complex NAC in the cell helps to prevent the aggregration of proteins associated with several neurodegenerative diseases. (2019-04-11)
Crucial 'electrical switch' in brain revealed in study published by Science
Scientists have revealed the structure of a critical receptor in the brain associated with learning, memory, behavior and mood. (2019-04-11)
Aging gracefully: Study identifies factors for healthy memory at any age
University of Alberta neuroscientists have identified different factors for maintaining healthy memory and for avoiding memory decline in those over age 55, according to a new study. (2019-04-10)
Scientists create molecular tool to remove toxic protein from neuronal models of dementia
Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital have successfully cleared patient-derived brain cells of an abnormal protein associated with dementia and other neurogenerative disorders. (2019-04-09)
How education may stave off cognitive decline
Prefrontal brain regions linked to higher educational attainment are characterized by increased expression of genes involved in neurotransmission and immunity, finds a study of healthy older adults published in JNeurosci. (2019-04-08)
Researchers find brain molecular features associated with years of education
A study led by a team from the University of Barcelona identified greater cortical thickness in the frontal lobe in a group of old people with high levels of education. (2019-04-08)
How good are protein disorder prediction programs actually?
Until now it was difficult to answer this question, as a good benchmark for testing these bioinformatics programs was lacking. (2019-04-05)
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