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Current Neurodegenerative diseases News and Events

Current Neurodegenerative diseases News and Events, Neurodegenerative diseases News Articles.
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Protecting the neuronal architecture
Protecting nerve cells from losing their characteristic extensions, the dendrites, can reduce brain damage after a stroke. (2020-06-05)
UTEP researchers help bring biofriendly materials to drug design for neuro disorders
The contributions of researchers from The University of Texas at El Paso have yielded the first indication that carbon quantum dots, a class of nanoparticles, can be utilized to combat neurological disorders, according to a paper published in the journal Processes as part its special issue on protein biosynthesis and drug design and delivery. (2020-06-05)
New microscopy method provides unprecedented look at amyloid protein structure
Neurodegenerative diseases such as Alzheimer's and Parkinson's are often accompanied by amyloid proteins in the brain that have become clumped or misfolded. (2020-06-04)
Insight into protein misfolding could open up new approaches to treat Parkinson's disease
Researchers have uncovered a link between the structure of the protein alpha-synuclein and its likelihood to misfold and aggregate. (2020-06-04)
Psoriasis patients' mental health is more than skin-deep
A new study from Umeå University, Sweden, shows that other somatic diseases have even more impact on patients' mental health than their skin symptoms, highlighting the importance of holistic patient care. (2020-06-04)
Growth factors and Parkinson's disease -- Where next?
Growth factors such as glial cell line-derived neurotrophic factor (GDNF) were initially thought to be exciting new treatments for Parkinson's disease (PD), but trials have been disappointing. (2020-06-04)
With faster cell modeling towards the vaccine and cure for COVID-19
Researchers from the Department of Chemistry, Materials and Chemical Engineering 'Giulio Natta' of the Politecnico di Milano and the Pediatric Research Center, Department of Biomedical and Clinical Sciences 'L. (2020-06-04)
Neurobiology of Disease publishes results of AFFiRiS' antibody mAB C6-17 in Huntington's
Monoclonal antibody mAB C6-17 targeting human/mutant huntingtin protein (HTT/mutHTT) was developed and characterized. (2020-06-03)
App promises to improve pain management in dementia patients
University of Alberta computing scientists are developing an app to aid health-care staff to assess and manage pain in patients suffering from dementia and other neurodegenerative diseases. (2020-06-02)
Discovery of proteins that regulate interorganelle communication
This groundbreaking discovery of the key factor in the formation of MAM is expected to contribute to research on Neurodegenerative Diseases. (2020-06-02)
Researchers control cattle microbiomes to reduce methane and greenhouse gases
''Now that we know we can influence the microbiome development, we can use this knowledge to modulate microbiome composition to lower the environmental impact of methane from cows by guiding them to our desired outcomes,'' Ben-Gurion University of the Negev Prof Mizrahi says. (2020-06-01)
When astrocytes attack: Stem cell model shows possible mechanism behind neurodegeneration
A new study published today in Neuron led by The New York Stem Cell Foundation (NYSCF) Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain -- from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers. (2020-06-01)
Researchers develop new method to map cholesterol metabolism in brain
A team of researchers led by Swansea University have developed new technology to monitor cholesterol in brain tissue which could uncover its relation to neurodegenerative disease and pave the way for the development of new treatments. (2020-05-29)
Biophysicists reveal how optogenetic tool works
An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state. (2020-05-28)
New marine molecules with therapy potential against Alzheimer's disease
An interdisciplinary research study of the University of Barcelona identified two potential candidates to treat Alzheimer's disease. (2020-05-28)
New evidence for a blood-based biomarker for Alzheimer's disease
Neurofilament light chain (NfL) has great potential as a biomarker for early detection of Alzheimer's disease and could be also useful for monitoring treatment response for that condition. (2020-05-27)
The analysis of copper levels in blood facilitates diagnosis of Alzheimer's disease
In biology it is well-known that every living organism is triggered by the hereditary material or DNA that encodes various protein molecules, which in turn perform all the necessary biological functions and it might seem that nothing else is needed to sustain the life of an organism. (2020-05-26)
A natural amino acid could be a novel treatment for polyglutamine diseases
Researchers from Osaka University, National Center of Neurology and Psychiatry, and Niigata University identified the amino acid arginine as a potential disease-modifying drug for polyglutamine diseases, including familial spinocerebellar ataxia and Huntington disease. (2020-05-25)
New therapy for triple negative breast cancer
Researchers at the Principe Felipe Research Center (CIPF), the Universitat Politècnica de València (UPV), CIBER-BBN and the Institute for Research in Biomedicine (IRB) of Barcelona have inhibited tumor growth and reduced metastasis, as well as the toxicity of the antitumor drug Navitoclax in preclinical animal models of triple negative breast cancer (TNBC). (2020-05-25)
Mechanism behind upper motor degeneration revealed
Scientists have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, such as Hereditary Spastic Paraplegia and Primary Lateral Sclerosis. (2020-05-21)
Cutting edge two-photon microscopy system breaks new grounds in retinal imaging
In a recent breakthrough, a team of HKUST scientists developed an adaptive optics two-photon excitation fluorescence microscopy using direct wavefront sensing for high-resolution in vivo fluorescence imaging of mouse retina, which allow in vivo fundus imaging at an unprecedented resolution after full AO correction. (2020-05-20)
Animal study shows human brain cells repair damage in multiple sclerosis
A new study shows that when specific human brain cells are transplanted into animal models of multiple sclerosis and other white matter diseases, the cells repair damage and restore function. (2020-05-19)
Protein shapes matter in Alzheimer's research
Even a small change may cause long-term consequences. For amyloid beta peptides, a major hallmark of Alzheimer's disease, a common chemical modification at a particular location on the molecule has a butterfly effect that leads to protein misfolding, aggregation and cellular toxicity. (2020-05-19)
Study finds that aging neurons accumulate DNA damage
MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. (2020-05-18)
Simple molecular reagents to treat Alzheimer's disease
Sometimes the most complex problems actually have very simple solutions. (2020-05-11)
Who takes the temperature in our cells?
The conditions in the environment are subject to large fluctuations. (2020-05-11)
Genetic doppelgaengers: Emory research provides insight into two neurological puzzles
Insight into the pathological mechanisms behind two devastating neurodegenerative diseases: the most common inherited form of amyotrophic lateral sclerosis/ frontotemporal dementia (ALS/FTD) and spinocerebellar ataxia type 36 (SCA36). (2020-05-05)
Unraveling one of prion disease's deadly secrets
In a new paper in Nature Structural and Molecular Biology by Tricia Serio, dean of the College of Natural Sciences and professor of biochemistry and molecular biology at UMass Amherst, and others, report an unanticipated role for prion nucleation seeds that enhances their ability to appear and resist curing. (2020-05-05)
HudsonAlpha scientists collaborate to uncover a gene that doubles the risk of developing several neurodegenerative diseases
Scientists at the HudsonAlpha Institute for Biotechnology, the University of California, San Francisco (UCSF), and the University of Alabama at Birmingham (UAB), have identified a new risk factor for multiple neurodegenerative diseases. (2020-04-27)
Sanfilippo C syndrome: New brain cell models to evaluate therapies
The Sanfilippo syndrome type C is a severe neurodegenerative disease which appears during the first years of life and for which there is no treatment yet. (2020-04-24)
Substituting the next-best protein
Children born with Duchenne muscular dystrophy have a mutation in the X-chromosome gene that would normally code for dystrophin, a protein that provides structural integrity to skeletal muscles. (2020-04-24)
A study finds neuropeptide somatostatin enhances visual processing?
Researchers have confirmed that neuropeptide somatostatin can improve cognitive function in the brain. (2020-04-23)
UTEP researchers develop nanohybrid vehicle to optimally deliver drugs into the human body
The researchers discovered that encapsulating ellagic acid in chitosan, a sugar, reduces its inherent cytotoxicity while enhancing its antioxidant properties. (2020-04-23)
How do our cells respond to stress?
Molecular biologists reverse-engineer a complex cellular structure that is associated with neurodegenerative diseases such as ALS (2020-04-21)
Solving the puzzle of Mitchell disease
Researchers discovered that ACOX1 is involved in two distinct neurodegenerative disorders. (2020-04-16)
Large-scale analysis links glucose metabolism proteins to Alzheimer's disease biology
In the largest study to date of proteins related to Alzheimer's disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers. (2020-04-13)
Toxic cell atlas guides new therapies for neurodegeneration
Researchers at Gladstone Institutes have identified a comprehensive molecular profile or 'atlas' of the toxic immune cells that damage the brain. (2020-04-13)
Inhibition of sphingolipid metabolism and neurodegenerative diseases
Disrupting the production of a class of lipids known as sphingolipids in neurons improved symptoms of neurodegeneration and increased survival in a mouse model. (2020-04-13)
Brain discovery suggests source of lifelong behavioral issues
The finding also could have important implications for a wide range of neurodegenerative diseases, such as Alzheimer's and Parkinson's. (2020-04-08)
A bad egg does good for its mother
There is plenty of scientific evidence that the health of a mother can impact the health of her child. (2020-04-08)
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