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Current Nucleic acid therapeutics News and Events

Current Nucleic acid therapeutics News and Events, Nucleic acid therapeutics News Articles.
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Ascorbic acid-mediated reactions in organic synthesis
In this review, we report ascorbic acid-catalyzed reactions in organic synthesis. (2020-09-25)
COVID-19 infected workers return to work faster using time and symptom-based protocols
Recently, investigators assessed the experience of using a test-based protocol in over 1000 infected health care workers. (2020-09-24)
NTU Singapore scientists devise 'Trojan horse' approach to kill cancer cells without using drugs
Cancer cells are killed in lab experiments and tumour growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct, a research team at the Nanyang Technological University, Singapore (NTU Singapore) has found. (2020-09-23)
A Sudoku-solving algorithm holds promise for protein medicine
Computational biologists from the University of Toronto have developed an artificial intelligence algorithm that has the potential to design novel protein molecules as finely tuned therapeutics. (2020-09-23)
Researchers find new way to protect plants from fungal infection
Widespread fungal disease in plants can be controlled with a commercially available chemical that has been primarily used in medicine until now. (2020-09-22)
Ribeye-eating pigs demonstrate protein quality for humans
Nearly a decade ago, the UN's Food and Agriculture Organization (FAO) developed a new index to assess protein quality in foods. (2020-09-21)
VCU study shows the experimental drug AR-12 could be a promising COVID-19 treatment
A team of scientists led by Paul Dent, Ph.D., at Virginia Commonwealth University Massey Cancer Center has discovered that an experimental cancer drug called AR-12 inhibits the SARS-CoV-2 virus, the cause of the COVID-19 pandemic, from infecting cells and replicating. (2020-09-21)
Unexpected wildfire emission impacts air quality worldwide
During wildfires, nitrous acid plays a leading role--spiking to levels significantly higher than scientists expected, driving increased ozone pollution and harming air quality, according to a new study led by the University of Colorado Boulder and the Belgian Institute for Space Aeronomy. (2020-09-21)
CRISPR-based malaria testing on-the-fly
A multi-disciplinary research collaboration which was led by Harvard's Wyss Institute for Biologically Inspired Engineering and the Massachusetts Institute of Technology (MIT), created a field-applicable, ultrasensitive diagnostic assay that specifically detects DNA sequences from all Plasmodium species in symptomatic and asymptomatic malaria. (2020-09-21)
Evolutionary paths: Scientists have found new patterns in protein evolution
Russian scientists studied the trends in the evolution of amino acid sequences of proteins in vertebrates and insects. (2020-09-18)
After developing CRISPR test, UConn researchers validate clinical feasibility for COVID-19 testing
In March, researchers in the Department of Biomedical Engineering-- a shared department in the schools of Dental Medicine, Medicine, and Engineering--began to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including HIV virus, the novel coronavirus (SARS-CoV-2). (2020-09-18)
Time-restricted feeding improves health without altering the body's core clock
For the first time, scientists have studied the early effects of time-restricted feeding on the daily periodic oscillations of metabolites and genes in muscle, and metabolites in blood. (2020-09-17)
Progress toward antiviral treatments for COVID-19
COVID-19 is caused by the virus SARS-CoV-2, which is structurally similar to the viruses that cause SARS-CoV and MERS-CoV. (2020-09-15)
Study shows difficulty in finding evidence of life on Mars
While scientists are eager to study the red planet's soils for signs of life, researchers must ponder a considerable new challenge: Acidic fluids - which once flowed on the Martian surface - may have destroyed biological evidence hidden within Mars' iron-rich clays, according to researchers at Cornell University and at Spain's Centro de Astrobiología. (2020-09-15)
Fish oil without the fishy smell or taste
A new study, co-led by University of Cincinnati researchers, describes the development of a refining process that scientists deem a superior method to help produce better dietary omega-3 health and dietary supplements containing fish oil. (2020-09-15)
Drug for common liver condition may be an effective treatment for dementia
A team of researchers, led by the University of York, have identified new proteins involved in protecting neurons and discovered that Ursodeoxycholic Acid - an already approved drug, with very low toxicity - increases these proteins and protects neurons from death. (2020-09-14)
Consumption of sheep or beef liver can contribute considerably to the total intake of PFAS
Per- and polyfluoroalkyl substances (PFAS) are industrial chemicals that have been used for decades in several industrial processes and consumer products due to their special technical properties. (2020-09-14)
New study from MD Anderson and BridgeBio's Navire Pharma shows SHP2 inhibition overcomes multiple therapeutic-resistance mechanisms in lung cancer
New preclinical research from MD Anderson and Navire finds a novel drug targeting SHP2 can overcome multiple paths of therapeutic resistance in lung cancer. (2020-09-14)
Novel immune-oncology approach for potential cancer treatment
A research collaboration between Monash University and Lava Therapeutics details a novel immune-oncology approach for the potential treatment of cancer. (2020-09-14)
Rubbery properties help RNA nanoparticles target tumors efficiently and quickly leave body
A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. (2020-09-14)
Successful improvement of the catalytic activity of photosynthetic CO2 fixing enzyme Rubisco
A research group consisting of Associate Professor FUKAYAMA Hiroshi (Kobe University) and Professor MATSUMURA Hiroyoshi (Ritsumeikan University) et al. have succeeded in greatly increasing the catalytic activity of Rubisco, the enzyme which fixes carbon from CO2 in plant photosynthesis. (2020-09-14)
Lab-on-paper strip: Small, inexpensive platform for diagnosing tropical fevers
Dengue, zika, and chikungunya viruses are transmitted by mosquitoes and cause tropical fevers with similar symptoms, making accurate diagnosis complicated. (2020-09-11)
Cancer drug can rebalance kidney function in a devastating genetic disease
Researchers at the University of Cambridge and the University of Zurich have discovered that a drug newly approved for cancer improves kidney dysfunction in a mouse model of Dent disease 2 and Lowe syndrome (2020-09-09)
Small proteins against SARS-CoV-2 neutralize infection in cell culture
Using innovative computer-based approaches, researchers have developed protein inhibitors that block the interaction between the SARS-CoV-2 virus and human cell receptor ACE2. (2020-09-09)
Pro-inflammatory lipids precede Type 1 diabetes onset in mouse model and children
Type 1 diabetes is an autoimmune disease where immune cells -- led by inflammatory macrophages -- attack and destroy the pancreatic beta cells. (2020-09-09)
Finding a handle to bag the right proteins
A method that lights up tags attached to selected proteins can help to purify the proteins from a mixed protein pool. (2020-09-09)
Brain's immune cells promising cellular target for therapeutics
Inspired by the need for new and better therapies for neurodegenerative diseases, researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia, which are emerging as a promising cellular target because of the prominent role they play in brain inflammation. (2020-09-08)
New nanosystem from Tel Aviv university enhances treatment for melanoma in animal models
Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma. (2020-09-08)
The Art of War: how bacteria gather intel for guiding their CRISPR-Cas systems
Researchers from the Severinov Lab at Skoltech have looked at how a poorly studied type of CRISPR-Cas defense system from a bacterium living at extremely high temperature gets to know its enemy by selecting snippets of bacteriophage's genetic information for a genetic 'database' it uses to ward off subsequent infections. (2020-09-08)
A new method may make tomatoes safer to eat
When vegetable farmers harvest crops, they often rely on postharvest washing to reduce any foodborne pathogens, but a new University of Georgia study shows promise in reducing these pathogens - as well as lowering labor costs-- by applying sanitizers to produce while it is still in the fields. (2020-09-08)
Novel insights of how prostate cancer causes secondary tumors
An increased awareness on a molecular level of what mechanisms prostate cancer cells use to become mobile and start spreading may in the long run provide new opportunities for treatment of aggressive prostate cancer. (2020-09-03)
Tryptophan supports guts health on trouts under stress, says a RUDN biologist
A biologist from RUDN University found the most beneficial concentration of tryptophan for rainbow trout. (2020-09-03)
Combining PCR and antibody tests at point of care dramatically increases COVID-19 detection
A Cambridge hospital has piloted the use of combined rapid point-of-care nucleic acid and antibody testing for SARS-CoV-2 infection after researchers at the University of Cambridge showed that this approach was superior to virus detection alone for diagnosing COVID-19 disease. (2020-09-02)
Japanese sake: the new pick-me-up? Yeast strain makes fatigue-fighting ornithine
Researchers from the Nara Institute of Science and Technology and the Nara Prefecture Institute of Industrial Development have found that that a mutant strain of sake yeast produces high levels of the amino acid ornithine. (2020-08-27)
Microbes working together multiply biomass conversion possibilities
Non-edible plants are a promising alternative to crude oil, but their heterogenous composition can be a challenge to producing high yields of useful products. (2020-08-27)
Antagonistic genes modify rice plant growth
Rice stems lengthen when a newly identified gene activates during flooding. (2020-08-26)
Hydrochloric acid boosts catalyst activity
A research team from the Technical University of Munich (TUM) led by chemist Johannes Lercher has developed a synthesis process which drastically increases the activity of catalysts for the desulfurization of crude oil. (2020-08-25)
Wireless device makes clean fuel from sunlight, CO2 and water
Researchers have developed a standalone device that converts sunlight, carbon dioxide and water into a carbon-neutral fuel, without requiring any additional components or electricity. (2020-08-24)
Microfluidic chip technology enables rapid multiplex diagnosis of plant viral diseases
Toyohashi University of Technology has applied a microfluidic chip technology to develop a multiplex genetic diagnostic device for the early detection and prevention of crop diseases. (2020-08-21)
Mass General researchers create bioluminescent tag to detect DNA break repair
A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan. (2020-08-21)
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