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Current Pancreatic cancer News and Events

Current Pancreatic cancer News and Events, Pancreatic cancer News Articles.
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Suicidality among adult survivors of childhood cancer
A recent study found that survivors of childhood cancer have a similar risk of having suicidal thoughts compared with other individuals, and they have lower risk of suicidal behaviors and suicidal death. (2020-09-23)
Oncotarget: A comprehensive analysis of clinical trials in pancreatic cancer
The cover for issue 38 of Oncotarget features Figure 3, 'Summary of the time and cost for drug development (modified from DiMasi et al [2016],' by Katayama, et al. which reported that Pancreatic cancer is the most aggressive common cancer and is desperately in need of novel therapies. (2020-09-23)
KRAS inhibitor sotorasib appears safe, achieves durable clinical benefit in early trial
For patients with advanced solid cancers and KRAS G12C mutations, the targeted therapy sotorasib, a KRAS G12C inhibitor, resulted in manageable toxicities and durable clinical benefits, particularly in lung and colorectal cancer, in Phase I study. (2020-09-20)
Algorithms uncover cancers' hidden genetic losses and gains
Limitations in DNA sequencing technology make it difficult to detect some major mutations often linked to cancer, such as the loss or duplication of parts of chromosomes. (2020-09-17)
A ferry protein in the pancreas protects it from the stress induced by a high-fat diet
Scientists at Tokyo Institute of Technology (Tokyo Tech) have now uncovered a key mechanism by which pancreatic function is maintained in response to a high-fat diet. (2020-09-16)
Biomarker reveals how aggressive biliary tract cancer is in patients
Researchers from University of Copenhagen and Herlev and Gentofte Hospital have discovered a biomarker that might predict the course of the disease in patients with the rare and aggressive biliary tract cancer (BTC). (2020-09-15)
Mayo Clinic and TGen ID potential targets for the most-deadly form of pancreatic cancer
In what is believed to be the most comprehensive analysis of adenosquamous cancer of the pancreas (ASCP), the Mayo Clinic and TGen team identified, in preclinical models, therapeutic targets for this extremely fast-moving and deadly form of pancreatic cancer, and identified already available cancer inhibitors originally designed for other types of cancer, according to a study published today in the journal Cancer Research. (2020-09-14)
Researchers develop rapid test for ovarian cancer detection
Researchers at the University of Turku, Finland, have developed a test for ovarian cancer detection with a sensitivity 4.5 times higher than that of the conventional laboratory test. (2020-09-11)
The web of death
Cancer is one of the most frequent causes of death. (2020-09-10)
New drug could improve life expectancy and quality for pancreatic cancer patients
First-in-class drug starves certain tumor types of the resources they need to grow and spread to other parts of the body. (2020-09-09)
New nanosystem from Tel Aviv university enhances treatment for melanoma in animal models
Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma. (2020-09-08)
Protein causes mutations that lead to breast cancer cell aggression
In her previous research, University of Alberta biochemist Ing Swie Goping identified that the protein, BCL-2 interacting killer (BIK), was associated with relapses in breast cancer patients. (2020-09-08)
CNIO researchers develop an effective strategy against KRAS mutant lung tumors in mice
Researchers achieved complete remission of 25% of lung tumours caused by the KRAS oncogene in mice by inactivating CDK4 and RAF1, two genes that act at different levels in the signalling pathway of this oncogene. (2020-09-08)
Men with larger waists more likely to die of prostate cancer
A study of more than 200,000 UK men, being presented at this year's European and International Conference on Obesity (ECOICO), held online this year from September 1-4, reveals that there is a link between central adiposity (concentration of body fat around the belly and waist) and the risk of death from prostate cancer. (2020-09-01)
Microgel immuno-acceptance method could improve pancreatic islet transplant success
Researchers at the Georgia Institute of Technology and University of Missouri have developed a new microgel drug delivery method that could extend the effectiveness of pancreatic islet transplantations -- from several years to possibly the entire lifespan of a recipient. (2020-08-31)
A surprising protein player in diabetes
Conducted by researchers at the Okinawa Institute of Science and Technology Graduate University and Riken Center of Integrative Medical Sciences, a study looking at pancreatic beta cells has found a link between a commonly found protein, a subset of switched-off genes and the development of diabetes. (2020-08-28)
Immune protein IL-17A responsible for lethal side effects of gastric cancer
The formation of scar tissue, or fibrosis, as gastric cancer disseminates throughout the peritoneum can be more lethal than the cancer itself and can interfere with chemotherapy. (2020-08-26)
Small change makes cancer vaccine more effective in animal tests
Tweaking the adenovirus spike protein induces a more robust immune reaction for a cancer vaccine against gastric, pancreatic, esophageal and colon malignancies in animal models. (2020-08-24)
In one cancer therapy, two halves are safer than a whole
Splitting one type of cancer drug in half and delivering the pieces separately to cancer cells could reduce life-threatening side effects and protect healthy, non-cancerous cells, a new study suggests. (2020-08-24)
Ludwig Chicago study identifies a novel drug target for the control of cancer metastasis
Researchers led by Ludwig Chicago Co-director Ralph Weichselbaum and Ronald Rock of the University of Chicago have identified in preclinical studies a potential drug target for curtailing cancer metastasis. (2020-08-24)
Key molecule responsible for poor prognosis of breast cancer identified
Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer. (2020-08-21)
Molecule secreted by cancer-associated fibroblasts promotes anticancer drug resistance
Joint research at Kumamoto University in Japan discovered a new mechanism for anticancer drug resistance in gastric cancer. (2020-08-21)
Sortilin may hold the key to combat pancreatic cancer more effectively
Pancreatic cancer has an extremely poor prognosis; it is the third most common cause of cancer deaths in the United States. (2020-08-20)
Intestinal bacteriophage alters effects of cancer therapies in mice
Enterococcus, a genus that includes common commensal bacteria found in the gut, harbors a bacteriophage that influences the effects of various cancer immunotherapies in ways that may be clinically relevant, researchers working in mice report. (2020-08-20)
First immune-evading cells created to treat type 1 diabetes
Salk Institute scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost of $14.4 billion annually. (2020-08-19)
Potency-enhancing drugs linked to decreased risks in men with colorectal cancer
A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer. (2020-08-17)
Regulation of cancer stemness by the best combination of nanotech and genetic engineering
Photo-active nanocomplexes are successfully developed. The nanocomplexes allow spatiotemporal controlling genetically-engineered cells that are overexpressing temperature-sensitive membrane proteins. (2020-08-17)
PARP inhibitor becomes new treatment option for some men with advanced prostate cancer
Results from an international clinical trial found that men with advanced prostate cancer who have mutated BRCA1/BRCA2 genes can be treated successfully with a targeted therapy known as rucaparib. (2020-08-14)
Study finds cancer mapping may solve puzzle of regional disease links
New statistical analysis finds cancer mapping may help question regional disease links. (2020-08-13)
Diabetes, weight change and pancreatic cancer risk
Researchers investigated an association between the duration of diabetes and recent weight loss with subsequent risk of pancreatic cancer in this observational study. (2020-08-13)
Study focuses on a different kind of liquid biopsy to detect cancer
In a study published August 13, 2020, in Cell by a team of collaborators from Memorial Sloan Kettering and Weill Cornell Medicine, researchers report that tiny packages of materials released by tumors, called EVPs (extracellular vesicles and particles), may serve as biomarkers for detecting a number of different types of cancer in the early stages. (2020-08-13)
Smoking strongly linked to women's lower take up of cancer screening services
Smoking is strongly linked to lower use of cancer screening services by women, and more advanced disease once cancer is diagnosed, reveals research published in the online journal BMJ Open. (2020-08-13)
Increased breast cancer risk in obesity linked to fat cell chemicals
Obesity increases the release of tumour-promoting molecules from fat tissue and is associated with an increased risk of breast cancer, according to a study published in Endocrine-Related Cancer. (2020-08-11)
COMBAT study preliminary results show response of 32% in treatment of pancreatic tumors
Working with an international team of researchers, HonorHealth Research Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, were instrumental in one of the first clinical trials showing how pancreatic cancer patients can benefit from immunotherapy, according to a four-year study published in a premier scientific journal, Nature Medicine. (2020-08-11)
Tel Aviv University scientists reduce metastatic spread following tumor removal surgery
A research group from Tel Aviv University (TAU) successfully reduced metastatic spread following tumor removal surgery in colorectal cancer patients. (2020-08-10)
HPV strains may impact cervical cancer prognosis
An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumours caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics and prognosis. (2020-08-10)
Study gauges specific site stomach cancer risks among ethnic groups
Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans. (2020-08-06)
Scientists discover novel drug target for pancreatic cancer
Scientists at Sanford Burnham Prebys Medical Discovery Institute have uncovered a novel drug target, a protein called PPP1R1B, that stops the deadly spread of pancreatic cancer, called metastasis, when inhibited in mice. (2020-08-05)
Move over Akita: Introducing 'Kuma mutant' mice for islet transplantation research
Scientists at the Tokyo Institute of Technology (Tokyo Tech) have used a gene editing technique to establish a novel mouse model of permanent neonatal diabetes--the immune-deficient Kuma mutant mice with a specific deletion in the Insulin2 (Ins2) gene. (2020-08-05)
New method to help spot gastric cancer cells
Researchers from the Shenyang Institute of Automation (SIA) of the Chinese Academy of Science (CAS) and City University of Hong Kong (CityU), in cooperation with doctors from the First Hospital of China Medical University, jointly proposed an optically induced electrokinetics (OEK) microfluidic method for label-free separation and characterization of gastric cancer cells. (2020-08-05)
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