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Current Pancreatic cancer News and Events

Current Pancreatic cancer News and Events, Pancreatic cancer News Articles.
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Rare genetic change provides clues to pancreas development
Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas. (2019-04-18)
Cervical cancer is more aggressive when human papillomavirus is not detected
Cervical cancer negative for the human papillomavirus (HPV) is rare but more aggressive: it is more frequently diagnosed at advanced stages, with more metastasis and reduced survival. (2019-04-17)
Key protein a possible new target in the treatment of pancreatic cancer
Pancreatic Cancer Collective-funded research (Lustgarten Foundation and Stand Up To Cancer) from Dr. (2019-04-17)
New study targets Achilles' heel of pancreatic cancer, with promising results
Advanced pancreatic cancer is often symptomless, leading to late diagnosis only after metastases have spread throughout the body. (2019-04-17)
Researchers pinpoint tumor-related protein, slow progression of cancers
A new study in Nature has identified a potential strategy for treating multiple forms of cancerous tumors: targeting a protein that maliciously rewires immune cells and impedes cancer therapies. (2019-04-17)
The fluid that feeds tumor cells
MIT biologists have found that the nutrient composition of the interstitial fluid that normally surrounds pancreatic tumors is different from that of the culture medium normally used to grow cancer cells. (2019-04-16)
Three studies show how tumors hijack the immune system to resist radiation therapy
Treg cells turn off the immune system. Three recent studies show that targeting tregs may increase the effectiveness of anti-cancer immunotherapies. (2019-04-16)
Rare but important gene target found in many tumor types, suggesting new therapy possible
A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion they believe is responsible for development of a wide spectrum of cancer types. (2019-04-15)
Scientists get sly, use deception to fight cancer
In recent years, it's become clear that RNA-binding proteins play a major role in cancer growth. (2019-04-15)
Decoding cancer's molecular signature
New algorithm successfully identifies patients with a tumor-fueling DNA repair defect found in multiple cancers and treatable with a common cancer drug. (2019-04-15)
Precise decoding of breast cancer cells creates new option for treatment
Researchers at the University of Zurich and from IBM Research have investigated the vary-ing composition of cancer and immune cells in over one hundred breast tumors. (2019-04-15)
Some patients with imminently fatal cancer still receive treatment
Patients who died within one month of being newly diagnosed with metastatic cancer in the United States received ineffective surgery, chemotherapy, radiation, and hormonal therapy. (2019-04-15)
CNIO researchers succeed at removing some types of pancreatic cancer in animal models
Until now, no full regression had been observed in advanced pancreatic cancer in experimental models. (2019-04-11)
'Nanobodies' from alpacas could help bring CAR T-cell therapy to solid tumors
Most CAR T-cell therapies look for antigens specific to cancer cells. (2019-04-11)
One-third of cancer patients use complementary and alternative medicine
A stunning one-third of people with a cancer diagnosis use complementary and alternative medicines such as meditation, yoga, acupuncture, herbal medicine, and supplements. (2019-04-11)
Identification of lymph node cells that may play important roles in immune tolerance
Aire-expression in the thymus is crucial in immune tolerance by eliminating auto-reactive T cells; insufficient elimination causes autoimmune disorders. (2019-04-10)
Cancer drug shortages result in almost no treatment changes, USC study finds
For the vast majority of cancer drugs experiencing shortages over a seven-year period, a new USC research study found no statistically significant effect of shortages on chemotherapy treatment. (2019-04-08)
TGen review links gene with the most common liver cancer
In an article published in the scientific journal Cancers, researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, provide the first summary of the experimental evidence supporting the AKR1B10 enzyme as a promising therapeutic target for Hepatocellular carcinoma (HCC), based on a review of more than 50 studies published since this gene was first identified and characterized in 1998. (2019-04-08)
Study calculates costs associated with smoking by patients with cancer
A study released today in JAMA Network Open reported that smoking after a cancer diagnosis is associated with substantial additional costs of cancer treatment. (2019-04-05)
Genome-wide analysis reveals new strategies to target pancreatic cancer
An international team of scientists led by researchers at University of California San Diego School of Medicine employed an array of next-generation sequencing and gene-editing tools, such as CRISPR, to map the molecular dependencies - and thus vulnerabilities -- of pancreatic cancer stem cells. (2019-04-04)
New formula better predicts speed of tumor growth in 12 cancers
University at Buffalo researchers have developed a new method to more accurately predict tumor growth rates, a crucial statistic used to schedule screenings and set dosing regimens in cancer treatment. (2019-04-03)
Mayo Clinic finds 3 factors extend life for advanced pancreatic cancer patients
Historically, most pancreatic cancer patients whose tumors grow outside the pancreas to encompass veins and arteries have been told the cancer is inoperable and they should prepare for an average survival time of 12 to 18 months. (2019-04-02)
PARP inhibitors can shrink tumors in pancreatic cancer patients with specific mutations
Switching pancreatic cancer patients to the PARP inhibitor rucaparib as maintenance therapy may represent new treatment paradigm for pancreatic cancer patients with BRCA mutations. (2019-04-02)
Maintenance therapy with rucaparib shows clinical responses in a subgroup of patient with pancreatic cancer
Maintenance treatment with the PARP inhibitor rucaparib (Rubraca) was well tolerated and provided clinical responses among patients with advanced BRCA- or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, according to results from an interim analysis of an ongoing phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)
AACR: Adavosertib speeds cancer cells into the wall of mitotic catastrophe
A University of Colorado Cancer Center study presented at AACR 2019 shows that inhibiting the action of Wee1 speeds cancer cells with damaged DNA through cell cycle, leading to mitotic catastrophe. (2019-04-01)
Tobacco use makes precancerous cells that fertilize cancer growth
Inhibiting EGFR along with PI3K may negate EGFR escape route that precancerous cells provide to cancer cells to avoid PI3K inhibitors. (2019-04-01)
Immune checkpoint inhibitor combo efficacious for patients with neuroendocrine carcinoma
A combination of the anti-CTLA-4 immunotherapeutic ipilimumab (Yervoy) and the anti-PD-1 immunotherapeutic nivolumab (Opdivo) showed clinical benefit among patients with rare, high-grade neuroendocrine carcinoma, according to results from the DART phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-03-31)
CD40 combination therapy can shrink pancreatic tumors
A new combination of immunotherapy and chemotherapy for pancreatic cancer caused tumors to shrink in the majority of evaluable patients. (2019-03-31)
Excess body weight before 50 is associated with higher risk of dying from pancreatic cancer
Excess weight before age 50 may be more strongly associated with pancreatic cancer mortality risk than excess weight at older ages, according to results of a study presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-03-31)
Poor oral health may increase the risk of pancreatic cancer among African American women
African American women with poor oral health may be more likely to get pancreatic cancer (PC). (2019-03-28)
Researchers target metastasis in fight against cancer
An experimental combination drug therapy attacking the DNA integrity of cancer cells is showing promise for a possible new cancer therapy in the future. (2019-03-28)
Two novel pancreatic cancer cell lines with highly metastatic activity were established and analyzed
A recent research established two human pancreatic cancer cell sublines with high metastasis potential, MIA PaCa-2 In8 and Panc-1 In8, by Matrigel induction assay. (2019-03-27)
New potential therapeutic target for pancreatic cancer discovered
Cancer cells demand enormous amounts of molecular 'food' to survive and grow, and a study published March 27 online in Nature by researchers at The University of Texas MD Anderson Cancer Center may have identified a new approach to starve the cells of one of the most common and deadly cancers, pancreatic cancer. (2019-03-27)
Protein 'spat out' by cancer cells promotes tumor growth
Prostate cancer cells change the behavior of other cells around them, including normal cells, by 'spitting out' a protein from their nucleus, new research has found. (2019-03-26)
Tumor-associated immune cells hinder frontline chemotherapy drug in pancreatic cancer
A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found. (2019-03-26)
Are preventive drugs overused at the end of life in older adults with cancer?
A new study reveals that preventive medications -- such as those to lower blood pressure or cholesterol, or to protect bone health, among others -- are commonly prescribed during the last year of life of older adults with cancer, even though they are unlikely to provide meaningful benefits. (2019-03-25)
Researchers reveal new molecular mechanism involved in pancreas repair
Ramón Muñoz-Chápuli and Rita Carmona, researchers of the UMA Department of Animal Biology, have identified a new molecular mechanism involved in pancreas repair. (2019-03-25)
Drinking hot tea linked with elevated risk of esophageal cancer
Previous studies have revealed a link between hot tea drinking and risk of esophageal cancer, but until now, no study has examined this association using prospectively and objectively measured tea drinking temperature. (2019-03-20)
Baby step towards breath-testing for gut disorders
Small children may one day avoid invasive, painful and often traumatic esophageal tube-testing for gut damage and celiac disease with a new method of simply blowing into a glass tube to provide effective diagnoses. (2019-03-20)
Balance of two enzymes linked to pancreatic cancer survival
UC San Diego School of Medicine research sets the stage for clinicians to potentially one day use levels of a pancreatic cancer patient's PHLPP1 and PKC enzymes as a prognostic, and for researchers to develop new therapeutic drugs that inhibit PHLPP1 and boost PKC as a means to treat the disease. (2019-03-20)
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