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Current Placebo News and Events, Placebo News Articles.
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Darolutamide in prostate cancer: Indication of considerable added benefit
The advantages in the outcome categories of mortality, morbidity and health-related quality of life are not accompanied by disadvantages. (2020-08-03)
The Lancet Psychiatry: First clinical trial of its kind studies whether cannabidiol could help treat cannabis use disorder, compared to placebo
Prescription medication of cannabis extract cannabidiol, or CBD, is safe for daily use in treating cannabis use disorder, and could help people to cut down on cannabis use, according to an initial randomised controlled trial published in The Lancet Psychiatry journal. (2020-07-28)
Prescribed CBD could help people quit cannabis
A benchmark clinical trial published today shows that cannabidiol (CBD) could be a safe and effective treatment for problematic cannabis use. (2020-07-28)
Cannabis shows potential for mitigating sickle cell disease pain
Cannabis appears to be a safe and potentially effective treatment for the chronic pain that afflicts people with sickle cell disease, according to a new clinical trial co-led by University of California, Irvine researcher Kalpna Gupta and Dr. (2020-07-17)
Single-dose flu drug can reduce spread within households, study finds
Only 1.9% of uninfected household members who took a single dose of baloxavir marboxil came down with the flu. (2020-07-13)
Teva presents latest data on AJOVY® ▼ (fremanezumab) at EHF Congress
Teva Pharmaceutical Europe B.V. has presented results from a pooled analysis of three randomized, double-blind, placebo-controlled Phase 3 studies assessing AJOVY® ▼ (fremanezumab), indicated for the preventative treatment of migraine in adults, which demonstrate clinically significant reductions in headache and migraine-related disability in the majority of patients studied. (2020-07-09)
Experimental drug shows early promise against inherited form of ALS, trial indicates
A clinical trial conducted at Washington University School of Medicine in St. (2020-07-08)
Medicinal cannabis may reduce behavioral problems in kids with intellectual disabilities
Cannabidiol, a type of medicinal cannabis, may reduce severe behavioural problems in children and adolescents with an intellectual disability a new study has found. (2020-06-24)
Endogenous insulin production is preserved in Type 1 diabetes with anti-TNF drug
A study led by a UB researcher found that a drug called golimumab preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study. (2020-06-16)
New findings from groundbreaking study shows extended delay in onset of type 1 diabetes
Data presented today at the ADA 80th Scientific Sessions by Emily Sims, M.D. details the Phase 2 Teplizumab Prevention Study Clinical Trial findings that showed a two-week course of teplizumab delayed the onset of clinical T1D by three years. (2020-06-15)
Antihypotensive agent disrupts the immune system in sepsis
Patients who go into shock caused by sepsis (septic shock) are treated with the antihypotensive agent norepinephrine. (2020-06-11)
An aspirin a day keeps the bowel doctor away
A regular dose of aspirin to reduce the risk of inherited bowel cancer lasts at least 10 years after stopping treatment, research has revealed. (2020-06-11)
Aspirin reduces long-term colorectal cancer risk in genetically predisposed individuals
Aspirin reduces colorectal cancer risk by half in individuals at high genetic risk. (2020-06-11)
Study shows cannabis temporarily relieves PTSD symptoms
People suffering from post-traumatic distress disorder report that cannabis reduces the severity of their symptoms by more than half, at least in the short term, according to a recent study led by WSU psychology professor Carrie Cutler. (2020-06-09)
Hope for patients with primary hyperoxaluria type 1
Lumasiran is a subcutaneously administered RNAi therapeutic targeting hydroxyacid oxidase 1 (HAO1) - the gene encoding glycolate oxidase (GO) - in development for the treatment of primary hyperoxaluria type 1 (PH1). (2020-06-07)
Empagliflozin -- kidney protection regardless of an initial 'eGFR dip'
Data presented today at the ERA-EDTA Congress show that empagliflozin is more likely to induce an initial 'dip' in eGFR in patients belonging to a higher KDIGO risk category and/or on diuretic therapy. (2020-06-07)
Systemic lupus erythematosus (SLE)
If renal remission is achieved therapeutically in cases of lupus nephritis (LN), the 10-year survival rate increases significantly. (2020-06-07)
Ribociclib in breast cancer: Added benefit for certain women after menopause
After expiry of the G-BA decisions, IQWiG reassessed the drug in two combinations. (2020-06-05)
Psychedelic drug psilocybin tamps down brain's ego center
Perhaps no region of the brain is more fittingly named than the claustrum, taken from the Latin word for 'hidden or shut away.' The claustrum is an extremely thin sheet of neurons deep within the cortex, yet it reaches out to every other region of the brain. (2020-06-05)
BIOCAD presents results of clinical trial proving efficacy of netakimab at EULAR 2020
BIOCAD presents results of clinical trial proving efficacy of netakimab in the treatment of psoriatic arthritis at the Annual European Congress of Rheumatology (EULAR 2020). (2020-06-04)
UMN trial shows hydroxychloroquine has no benefit over placebo in preventing COVID-19
Today, University of Minnesota Medical School researchers published the results from the first randomized clinical trial testing hydroxychloroquine for the post-exposure prevention of COVID-19. (2020-06-03)
New study shows how ketamine combats depression
The anaesthetic drug ketamine has been shown, in low doses, to have a rapid effect on difficult-to-treat depression. (2020-05-31)
Nilotinib appears safe and affects biomarkers in Alzheimer's disease clinical trial
A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer's disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy. (2020-05-29)
Doxycycline ineffective at shrinking aortic aneurysms in two-year study
Patients with a vascular condition called abdominal aortic aneurysm did not benefit from taking the common antibiotic doxycycline for two years to shrink the aneurysm when compared to those who took a placebo, according to a Vanderbilt University Medical Center (VUMC) study published in the Journal of the American Medical Association (JAMA). (2020-05-27)
Peer-reviewed data shows remdesivir for COVID-19 improves time to recovery
The investigational antiviral remdesivir is superior to the standard of care for the treatment of COVID-19, according to a report in NEJM. (2020-05-26)
Researchers find no benefit for treatment used to avoid surgery for abdominal aortic aneurysm
A new landmark study by researchers at the University of Maryland School of Medicine (UMSOM) found that patients with a vascular condition, called abdominal aortic aneurysm, received no benefits from taking a common antibiotic drug to reduce inflammation. (2020-05-26)
Modified clinical trial protocol created in response to urgency of COVID-19 pandemic
A new paper published online in the Annals of the American Thoracic Society describes a nimble, pragmatic and rigorous multicenter clinical trial design to meet urgent community needs in the face of the COVID-19 pandemic. (2020-05-19)
Icosapent ethyl found to significantly reduce revascularizations in statin patients
Patients with high lipid levels have an increased risk for ischemic events, despite statin therapy. (2020-05-14)
Olanzapine may help control nausea, vomiting in patients with advanced cancer
Olanzapine, a generic drug used to treat nervous, emotional and mental conditions, also may help patients with advanced cancer successfully manage nausea and vomiting unrelated to chemotherapy. (2020-05-07)
Trial questions benefits of organic nitrates for bone health
A new study published in the Journal of Bone and Mineral Research found that organic nitrates do not have clinically relevant effects on bone mineral density or bone turnover in postmenopausal women, and the medications caused significant side effects. (2020-05-06)
Potato power: Spuds serve high quality protein that's good for women's muscle
Researchers from McMaster University have found that the potato, primarily known as a starchy vegetable, can be a source of high-quality protein that helps to maintain muscle. (2020-05-05)
The Lancet Gasteroenterology & Hepatology: First clinical trial finds probiotic treatment with dead bacteria is better than placebo at alleviating symptoms of irritable bowel syndrome
Probiotic bacteria that have been killed by heat can significantly improve symptoms of irritable bowel syndrome (IBS) compared to placebo, and are not associated with any safety risk, according to a new 12-week, randomized, double-blind, placebo-controlled clinical trial with 443 patients published in The Lancet Gastroenterology & Hepatology journal. (2020-04-08)
Researchers offer hope for an oral, noninjectable treatment of acromegaly
Adults who need medical maintenance treatment of the growth hormone disorder acromegaly respond well to an investigational oral form of the drug octreotide, investigators of the Chiasma OPTIMAL study reported. (2020-03-31)
First FDA-approved drug for thyroid eye disease effective regardless of age, gender
Teprotumumab, the first FDA-approved medicine for thyroid eye disease, provides significant improvement in eye bulging, regardless of patient gender, age or smoking status, according to a study accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society. (2020-03-31)
Liraglutide can help adolescents with obesity manage their weight
Liraglutide 3.0 mg, approved by the United States Food and Drug Administration (FDA) as an adjunct to a reduced-calorie diet and increased physical activity to help adults with obesity manage their weight, appears to help adolescents too, according to an industry-sponsored randomized controlled trial. (2020-03-31)
Vericiguat improves outcomes in patients with worsening heart failure
Patients with worsening heart failure and reduced ejection fraction who received the investigational drug vericiguat had a significantly lower rate of cardiovascular death or heart failure hospitalization compared with those receiving a placebo, based on research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)
Intravenous sodium nitrite ineffective for out-of-hospital cardiac arrest
Among patients who had an out-of-hospital cardiac arrest, intravenous sodium nitrite given by paramedics during resuscitation did not significantly improve their chances of being admitted to or discharged from the hospital alive, according to research presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)
Alirocumab substantially reduces cholesterol in adult patients with HoFH
The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical trial presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)
Evinacumab cuts cholesterol levels by half in patients with HoFH
The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol to near-normal levels among patients with a rare cholesterol disorder, meeting the primary endpoint in the first randomized placebo-controlled trial of the drug, which is being presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC). (2020-03-30)
The placebo effect and psychedelic drugs: tripping on nothing?
A new study from McGill suggests that, in the right context, some people may experience psychedelic-like effects from placebos alone. (2020-03-30)
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