Current Prostate cancer News and Events

Current Prostate cancer News and Events, Prostate cancer News Articles.
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Social needs linked to low health-related quality of life among African American cancer survivors
Social needs--such as food and economic insecurity, poor housing and neighborhood conditions, and lack of access to transportation--were common in a group of African American cancer survivors in Detroit, and they were associated with lower health-related quality of life (HRQOL). The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). (2020-11-23)

New findings speed progress towards affordable gene therapy
In a promising advance for affordable, personalised medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells. (2020-11-20)

Prostate cancer: CRYM protein inhibits tumour growth
Prostate cancer is caused by elevated hormone levels, and tumours are generally treated using hormone therapy. A research team headed by Lukas Kenner of MedUni Vienna in collaboration with David Heery from the University of Nottingham/UK and Sarka Pospisilova and Suzanne Turner of the University of Brno/Czech Republic have shown that the protein μ-crystallin (CRYM) plays a significant part in tumour growth. The higher the levels of this protein that are present, the better the prognosis. (2020-11-18)

Vitamin D supplements may reduce risk of developing advanced cancer
In a secondary analysis of VITAL, a team led by investigators at Brigham and Women's Hospital has narrowed in on the connection between taking vitamin D supplements and risk of metastatic or fatal cancer. In a paper published in JAMA Network Open, the team reports that vitamin D was associated with an overall 17 percent risk reduction for advanced cancer. (2020-11-18)

Patients strongly favor banning bacon in hospitals, according to new survey
Most hospitalized patients favor eliminating processed meats--including bacon, deli meat, and sausage--from hospital menus to reduce cancer risk, according to a new survey published in the Journal of Hospital Management and Health Policy. (2020-11-18)

Existing antidepressant helps to inhibit growth of cancer cells in lab animals
New research has shown that the antidepressant sertraline helps to inhibit the growth of cancer cells. The substance acts on a metabolic addiction that allows different types of cancer to grow. This is shown by a study on cell cultures and lab animals by researchers at KU Leuven. (2020-11-17)

Common prostate cancer treatment may impair cardiorespiratory fitness, raise risk of CV death
Prolonged androgen deprivation therapy (ADT) can impair cardiorespiratory fitness and increase risk of cardiovascular death in prostate cancer patients with high risk of cardiovascular disease, according to a study in JACC: CardioOncology. The findings contribute further data supporting the need for cardiovascular disease (CVD) monitoring in patients who are living longer after successful cancer treatment. (2020-11-17)

'Vanished' or 'hidden' prostate cancer? Men with negative biopsies during active surveillance have good outcomes
Can early-stage prostate cancer ''vanish'' during follow-up? More likely the cancer is just ''hidden''--either way, negative biopsies during active surveillance for prostate cancer are associated with excellent long-term outcomes, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. (2020-11-17)

Cancer deaths resulted in more than 4 million potential years of life lost in 2017
Deaths from cancer accounted for more than 4 million potential years of life lost in 2017, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. (2020-11-13)

Why does COVID-19 seem to spare children?
Researchers at Vanderbilt University Medical Center (VUMC) and their colleagues have determined a key factor as to why COVID-19 appears to infect and sicken adults and older people preferentially while seeming to spare younger children. (2020-11-13)

State-level lung cancer screening rates not aligned with lung cancer burden in the US
A new study reports that state-level lung cancer screening rates were not aligned with lung cancer burden. (2020-11-12)

Respirator 2.0: new n95-alternative introduces sensors for a better fit
Investigators from Brigham and Women's Hospital and Massachusetts Institute of Technology have been working to design a better, reusable respirator that could serve as an alternative to an N95 respirator. In the latest iteration of their work, they have introduced sensors to inform the user if the respirator is on properly and whether the filters are becoming saturated. (2020-11-10)

Gene signature predicts whether localized prostate cancer is likely to spread
Columbia researchers have identified a gene signature in localized prostate cancer that predicts the cancer's odds of spreading and its response to a common treatment for advanced disease. (2020-11-10)

New analysis finds lung cancer screening reduces rates of lung cancer-specific death
Low-dose CT screening methods may prevent one death per 250 at-risk adults screened, according to a meta-analysis of eight randomized controlled clinical trials of lung cancer screening. Researchers at the University of Georgia analyzed the health outcomes of 90,275 patients, comparing those who were screened versus those who received usual medical care or chest x-rays. (2020-11-10)

New cancer drugs saved over 1.2 million people in the US over 16 years, new study shows
More than 1.2 million people in the US prevented facing death following a cancer diagnosis, between the year 2000 and 2016, thanks to ever improving treatment options -- a large new national study shows. (2020-11-09)

Study examines health literacy and shared decision-making in prostate cancer screening
New research examines the dynamics between men's health literacy, their discussions with their doctors, and their decisions on whether to get tested for prostate-specific antigen (PSA), a potential marker of prostate cancer. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). (2020-11-09)

New research supports clinical utility of CTC count for metastatic breast cancer
Menarini Silicon Biosystems, the pioneer of liquid biopsy technology, today announced the publication of a research study providing support for the reliability of using circulating tumor cell (CTC) count to guide frontline therapy choice for patients with estrogen receptor-positive (ER+), HER2-negative (HER2) metastatic breast cancer. Published in the November issue of JAMA Oncology, this is the first study to support clinical utility of CTC count in a randomized clinical trial. (2020-11-09)

Low risk of cancer spread on active surveillance for early prostate cancer
Men undergoing active surveillance for prostate cancer have very low rates - one percent or less - of cancer spread (metastases) or death from prostate cancer, according to a recent study published in the Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer. (2020-11-09)

Large-scale cancer proteomics study profiles protein changes in response to drug treatments
Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms and to identify optimal combination treatment strategies. (2020-11-05)

Blood cell mutations confound prostate cancer liquid biopsy results
Unrelated mutations, when present in the blood, can give false positive results in men with advanced prostate cancer undergoing liquid biopsies. Such tests, which look for variants in cell-free DNA that tumors shed into the blood plasma, help determine suitable treatment options. Incorrect test results might mean the patient gets therapies unsuited for his cancer. A simple solution overcomes this problem. (2020-11-05)

Association between African American race, clinical outcomes in men treated for low-risk prostate cancer with active surveillance
This observational study estimates the 10-year risk for disease progression, surgery, metastasis, and cause-specific and all-cause mortality among African American men with low-risk prostate cancer managed with active surveillance. (2020-11-03)

Active surveillance safe for African Americans with low-risk prostate cancer
Researchers with UC San Diego School of Medicine and Moores Cancer Center say active surveillance is safe for African American men with low-risk prostate cancer. (2020-11-03)

Mayo Clinic study finds 1 in 8 patients with cancer harbor inherited genetic mutations
PHOENIX, Ariz. ? Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine. (2020-11-02)

Sexual health often overlooked in cancer survivorship care, especially for female patients
A new study points to a need for oncologists to ask their patients about sexual health after chemotherapy, radiation and other cancer treatments. In a survey of nearly 400 cancer survivors, 87% said they experienced sexual side effects, but most also said their oncologist had not formally asked about them. Female patients were especially unlikely to be asked about sexual dysfunction. Findings will be presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-30)

Greater prostate cancer incidence; mortality among Black men linked to genetic alterations
Prostate cancer tumors from African American men had higher frequencies of certain genetic alterations that may be associated with aggressive disease, compared with prostate cancer tumors from white men. (2020-10-28)

Outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer
Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants. (2020-10-28)

New imaging technique doubles visibility of brain tumors in scans
A new three-dimensional imaging technique has been developed that greatly improves the visibility of brain tumors in magnetic resonance imaging scans. The technique will potentially enable earlier diagnosis of tumors when they are smaller and more treatable. (2020-10-28)

Cancer's dangerous renovations to our chromosomes revealed
Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, new research reveals. (2020-10-27)

18F-Fluciclovine PET/MRI for prostate cancer staging, androgen deprivation evaluation
According to an open-access article in ARRS' American Journal of Roentgenology, fluorine-18-labeled fluciclovine PET/MRI demonstrated utility in the initial staging of high-risk prostate cancer, as well as for evaluating the response to androgen deprivation therapy. Given the FDA approval and widespread availability of 18F-fluciclovine, the findings could have impact in the immediate future in guiding initial management of patients with prostate cancer. (2020-10-27)

MFS Is a strong surrogate endpoint for OS for men receiving salvage RT for recurrent prostate cancer
An analysis of the phase III NRG Oncology clinical trial RTOG 9601 on men receiving salvage radiotherapy (SRT) following prostatectomy for recurrent prostate cancer indicated that, while biochemical failure (BF) was not a strong surrogate endpoint to determine overall survival (OS), metastasis-free survival (MFS) was in this patient population. (2020-10-26)

Genetic predisposition to increased weight is protective for breast and prostate cancer
A research study presented at the ASHG 2020 Virtual Meeting suggests that found that increasing weight is causally protective for breast and prostate cancer. (2020-10-26)

Adding advanced PET scans to radiation plans for prostate cancer increases FFS rates
Adding the advanced PET radiotracer fluciclovine to conventional imaging to help guide radiation treatments for recurrent prostate cancer can improve disease-free survival rates, a new study finds. Findings from the randomized phase II/III EMPIRE-1 trial (NCT01666808) will be presented today at the American Society for Radiation Oncology (ASTRO) Annual Meeting. (2020-10-26)

Effectiveness of gemcitabine & daily RT for bladder preservation in muscle-invasive bladder cancer
Bladder preservation with trimodality therapy can be a safe and effective alternative to cystectomy for selected patients with muscle-invasive bladder cancer. The phase II NRG Oncology NRG-RTOG 0712 trial evaluated two regimens. One was the prior RTOG standard using 5-flourouracil and cisplatin with twice daily radiation (FCT), and the other a regimen of gemcitabine and daily radiation (GD) which had demonstrated efficacy in single institution clinical trials. (2020-10-26)

ASTRO highlights Winship study showing increased failure-free survival in prostate cancer
The EMPIRE-1 trial is the first randomized trial of men with prostate cancer with recurring cancer to show that treatment based on advanced molecular imaging can improve disease-free survival rates. (2020-10-23)

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications. (2020-10-22)

Toward a new staging system for prostate cancer, and why it matters
The development and validation of a staging system for non-metastatic prostate cancer could help doctors and patients assess treatment options, as well as improve clinical trials. (2020-10-22)

Study reveals disparities in access to high-quality surgical care
Among U.S. patients diagnosed with breast, prostate, lung, or colorectal cancer from 2004 to 2016, those who were uninsured or had Medicare or Medicaid were less likely than privately insured patients to receive surgical care at high-volume hospitals. The findings are published in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). (2020-10-21)

Cholesterol medications linked to lower cancer-related deaths in women
Among women with breast cancer, colorectal cancer, or melanoma, those who were taking cholesterol-lowering medications, were less likely to die from cancer, according to an analysis published in the British Journal of Clinical Pharmacology. (2020-10-21)

Genomic differences may be key to overcoming prostate cancer disparities
In a new article published in Clinical Cancer Research, Moffitt Cancer Center researchers describes the immune-oncologic differences in prostate cancer tumors of African American men and how those variations may be exploited to develop more personalized treatment approaches for this population. (2020-10-21)

Existing heart drugs may help cancer patients respond better to PD(L)1 immunotherapy
Researchers have found that a class of commonly-used heart drugs may also improve patients' responses to anti-cancer immunotherapies called PD(L)1 inhibitors, according to preliminary findings to be presented at the 32th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online. (2020-10-21)

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