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Current Pulmonary fibrosis News and Events

Current Pulmonary fibrosis News and Events, Pulmonary fibrosis News Articles.
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A step toward helping patients breathe deeply
In a new study, researchers at La Jolla Institute for Immunology (LJI) report that a protein called TL1A drives fibrosis in several mouse models, triggering tissue remodeling, and making it harder for lungs and airways to function normally. (2020-09-24)
Study finds lung transplant patients not given antifungal preventive drugs have higher risk of death
Antifungal preventive medications reduce mortality risk by half in the first year following lung transplantation, according to Mayo Clinic research involving 667 patients who received lung transplants from 2005 to 2018. (2020-09-23)
BU researchers discover how COVID-19 may trigger fatal levels of lung inflammation
Responding to the COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2, requires models that can duplicate disease development in humans, identify potential targets and enable drug testing. (2020-09-21)
New virtual screening tool eases, accelerates routine diagnosis of pulmonary hypertension
The COVID-19 pandemic has increasing numbers of doctors caring for patients virtually. (2020-09-17)
DNA webs may drive lung pathology in severe COVID-19
Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental Medicine (JEM). (2020-09-14)
New treatments for deadly lung disease could be revealed by 3D modeling
A 3D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses. (2020-09-14)
Excessive lung release of neutrophil DNA traps may explain severe complications in Covid-19 patients
Researchers from the University of Liège (Belgium) has detected significant amounts of DNA traps in distinct compartments of the lungs of patients who died from Covid-19. (2020-09-14)
Drugging the undruggable: Yale finds treatment path for muscular dystrophy
Researchers at Yale have identified a possible treatment for Duchenne muscular dystrophy (DMD), a rare genetic disease for which there is currently no cure or treatment, by targeting an enzyme that had been considered ''undruggable.'' The finding appears in the Aug. (2020-09-11)
COPD program decreases 30-day hospital readmission, may increase mortality
The 30-day readmission rate for patients with chronic obstructive pulmonary disease has decreased but the mortality rate has increased. (2020-09-10)
Researchers draw more links between vaping, smoking, young people, and coronavirus
Vapers, smokers, and non-smokers with chronic conditions are all at higher risk for COVID-19. (2020-09-09)
Rutgers-led national survey uncovers doctors' misconceptions about nicotine risks
Most doctors misperceive the risks of nicotine, the addictive chemical in tobacco products, according to a Rutgers-led national survey. (2020-09-09)
Elevated clotting factor V levels linked to worse outcomes in severe COVID-19 infections
ICU patients on ventilators who had abnormally high factor V activity were at higher risk for blood clots, and when factor V was lower, the risk for death was increased. (2020-09-08)
Rare immune cells drive gut repair
Scientists from King's College London have discovered an unexpected tissue reparative role for a rare immune cell type in the gut that could tip toward fibrosis or cancer if dysregulated. (2020-09-07)
COVID-19 patients suffer long-term lung and heart damage but it can improve with time
Two studies on COVID-19 to be presented at the European Respiratory Society International Congress show that 1) coronavirus patients can suffer long-term lung and heart damage but, for many, this tends to improve over time (findings from first, prospective follow-up of COVID-19 patients); 2) the sooner COVID-19 patients started a pulmonary rehabilitation programme after coming off ventilators, the better and faster their recovery. (2020-09-06)
New method of detecting illnesses including coronavirus and cystic fibrosis
A new and quicker method of diagnosing diseases in patients has been created by researchers. (2020-09-02)
Trial clarifies which patients with acute pulmonary embolism can be managed at home
Patients with acute pulmonary embolism can be selected for home management using the sPESI score or the Hestia criteria, according to results of the HOME-PE trial presented in a Hot Line session today at ESC Congress 2020.1 Principal investigator Professor Pierre-Marie Roy of the University Hospital of Angers, France said: ''The pragmatic Hestia method was at least as safe as the sPESI score for triaging haemodynamically stable pulmonary embolism patients for outpatient care.'' (2020-08-31)
Immune protein IL-17A responsible for lethal side effects of gastric cancer
The formation of scar tissue, or fibrosis, as gastric cancer disseminates throughout the peritoneum can be more lethal than the cancer itself and can interfere with chemotherapy. (2020-08-26)
New insights into mechanism of therapy to reduce liver fat and prevent fibrosis
A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease. (2020-08-26)
Metabolic syndrome linked to worse outcomes for COVID-19 patients
Patients hospitalized with COVID-19 who had a combination of high blood pressure, obesity and diabetes were over three times more likely to die from the disease, according to a new Tulane University study published in Diabetes Care. (2020-08-25)
Mount Sinai study finds COVID patients were most commonly readmitted to hospital for respiratory complications
Study describes characteristics of patients with COVID-19 who returned to the ER or required readmission to the hospital within 14 days of being discharged (2020-08-21)
Dilated blood vessels in the lung may explain low oxygen levels in severe cases of COVID-19
A new pilot study from the Icahn School of Medicine at Mount Sinai suggests that COVID-19 is causing significant dilation of the blood vessels of the lung, specifically the capillaries. (2020-08-20)
New practice guidelines on non-invasive ventilation in chronic stable Hypercapnic COPD
A subcommittee of the American Thoracic Society Assembly in Sleep and Respiratory Neurobiology has released new clinical practice guidelines to help advise clinicians on the optimal management of patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. (2020-08-17)
Protein produced by the nervous system may help treatments for inflammatory diseases
A Rutgers-led team discover a protein produced by nervous system may be key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD) (2020-08-17)
The CNIO pave the way for a future gene therapy to reverse pulmonary fibrosis associated with ageing
''Our results indicate that a new therapy may be developed to prevent the development of pulmonary fibrosis associated with ageing,'' says CNIO's Maria Blasco, principal investigator of the study * Lung tissue of patients with pulmonary fibrosis does not regenerate because the cells involved in lung generation have damaged telomeres, the ends of the chromosomes. (2020-08-10)
Dietary control of the healing of injury-induced inflammation
The purpose of this review is to describe the molecular components of the Resolution Response and how different dietary factors can either optimize or inhibit their actions. (2020-08-10)
Researchers characterize important regulators of tissue inflammation, fibrosis and regeneration
Although macrophages (cells involved in the detection and destruction of bacteria and other harmful organisms as well as dead cells) are classified as immune cells functioning in the activation and resolution of tissue inflammation, it is now clear that they are critically involved in a variety of disease processes, such as chronic inflammatory diseases, tumor growth and metastasis and tissue fibrosis. (2020-08-10)
Change isn't a good thing for Japanese rheumatoid arthritis patients
Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) that dramatically increases the risk of death. (2020-08-09)
COVID-19 - The virus and the vasculature
In severe cases of COVID-19, the infection can lead to obstruction of the blood vessels in the lung, heart and kidneys. (2020-08-07)
Adding another dimension to a cell culture model for pulmonary arterial hypertension
Pulmonary arterial hypertension is a rare disease in which excessive proliferation of the cells of pulmonary arterial walls obstructs the blood flow in the lungs. (2020-08-07)
Scientists discover curious clues in the war between cf bacteria
Several different kinds of bacteria can cause lung infections in people with cystic fibrosis. (2020-08-07)
Treatment option improves chances of survival for babies with rare cerebrovascular disorder
Endovascular treatment of vein of Galen aneurysmal malformation (VGAM) in babies with severe pulmonary hypertension can improve chances of survival, according to a study released today at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting. (2020-08-07)
Pulmonary fibrosis treatment shows proof of principle
A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with idiopathic pulmonary fibrosis (IPF). (2020-08-06)
Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. (2020-08-05)
Osteopontin, a protein not always as bad as it is made out to be
In an article published in the prestigious journal Aging Cell, the UPV/EHU's Lipids & Liver research group shows that contrary to expectations, physiological levels in the liver of osteopontin, a multifunctional protein linked to various serious diseases, need to be maintained during ageing to prevent the progression of ageing-related, non-alcoholic fatty liver disease. (2020-08-05)
Challenges in diagnosing hypersensitivity pneumonitis addressed in latest guidelines
More than 30 years after the last guidance on the clinical evaluation of hypersensitivity pneumonitis (HP), the American Thoracic Society - in collaboration with the Asociación Latinoamericana de Tórax or ALAT and the Japanese Respiratory Society- has developed new guidelines for clinicians. (2020-08-03)
COPD underdiagnosed in older adults, but can be managed
''Recognizing and Treating COPD in Older Adults'' the latest issue of the What's Hot newsletter from The Gerontological Society of America, addresses what is known about the prevalence, incidence, and impact of chronic obstructive pulmonary disease (COPD) in older adults. (2020-08-03)
LSU health pathologists publish first report on likely MIS involving the heart
A team of LSU Health New Orleans pathologists published what is believed to be the first case report on pathologic findings of vasculitis of the small vessels of the heart, which likely represents multisystem inflammatory syndrome (MIS). (2020-07-30)
Researchers find increase in comorbidities among hospitalized patients with heart failure
Melissa Caughey, PhD, instructor in the UNC/NC State Joint Department of Biomedical Engineering, is the senior author of a recently published study that shows an increase in comorbidities and mortality risk among hospitalized patients with acute decompensated HFpEF and HFrEF. (2020-07-30)
New insights into wound healing
Research from a multidisciplinary team led by Washington University may provide new insights into wound healing, scarring and how cancer spreads (2020-07-29)
Casting a wider net to catch more cases of pulmonary hypertension
Investigators took an evidence-based approach to determine the lower end of the risk spectrum for PH based on pulmonary vascular resistance (PVR), which is resistance against blood flow from the pulmonary artery to the lungs. (2020-07-28)
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