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Current Radiotherapy News and Events

Current Radiotherapy News and Events, Radiotherapy News Articles.
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Radionuclide therapy effective in high-grade neuroendocrine neoplasms
Peptide receptor radionuclide therapy (PRRT) has been shown to be safe and effective for patients with grade 3 (G3) neuroendocrine neoplasms (NENs), according to research presented at the Society of Nuclear Medicine and Molecular Imaging's (SNMMI) 66th Annual Meeting. (2019-06-25)
Survivors of childhood brain tumors experience lasting cognitive and socioeconomic burdens
Survivors of childhood brain tumors who received radiotherapy and were very young at the time of diagnosis may experience cognitive and socioeconomic burdens decades after treatment, according to a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. (2019-06-24)
Testing therapies on mini-tumors of head and neck cancer
Head and neck cancer is an aggressive type of cancer that often recurs, despite patients undergoing harsh treatments. (2019-06-17)
Radiation treatment increases cardiac risk for lung cancer patients
As advances in the treatment of non-small cell lung cancer (NSCLC) extend patients' lives, more of these patients are facing a different threat: adverse cardiovascular events, such as heart attacks and heart failure. (2019-06-10)
Scientists propose a fresh look at the role of ferroptosis in the development of cancer
Despite significant advances in medicine, cancer remains the second leading cause of death worldwide. (2019-06-06)
No increased risk of birth defects in children of fathers treated for testicular cancer
New research has found no increased risk of congenital malformations associated with treatment with radiotherapy or chemotherapy in children of fathers with testicular cancer. (2019-06-04)
Suggested benefit in PCV chemoradiotherapy for both IDH-mutant WHO-defined molecular subgroups
A recent, updated predictive analysis of the three WHO-defined molecular subgroups based on isocitrate dehydrogenase 1/2 (IDH) mutation status and 1p/19q co-deletion status represented in the high-risk treatment arms of the NRG Oncology clinical trial NRG-RTOG 9802 indicates that both IDH-mutant sub-groups (IDHmut-noncodel and IDHmut-codel) could benefit from the addition of PCV chemotherapy to radiotherapy treatment. (2019-06-03)
NRG oncology trial of metformin for non-small cell lung cancer
Initial results of NRG-LU001 indicate that, although the diabetes agent metformin was well-tolerated by patients, the agent has not clearly improved progression-free survival (PFS) or overall survival (OS) for trial participants with locally advanced non-small cell lung cancer (NSCLC). (2019-06-01)
NRG trial suggests total neoadjuvant therapy for locally advanced rectal cancer is safe
Results from the first experimental arm using veliparib as part of total neoadjuvant therapy (induction chemotherapy followed by chemoradiotherapy and surgery; TNT) in patients with locally advanced rectal adenocarcinoma on the NRG Oncology Phase II clinical trial NRG-GI002 were recently presented at the American Society of Clinical Oncology (ASCO) Annual Meeting. (2019-06-01)
CNIO researchers discover a new way to protect against high-dose radiation damage
Intensive radiotherapy can be toxic in 60% of patients with tumors located in the gastrointestinal cavity. (2019-05-30)
Women in developing countries need radiotherapy and vaccines for cervical cancer
Millions of women in low- and middle-income countries will need life-saving radiotherapy to treat their cervical cancer, despite the growth of essential human papilloma virus (HPV) vaccination prevention programs. (2019-05-28)
Black men less likely than nonblack men to adopt active surveillance
At a time when a growing number of men with prostate cancer considered 'low risk' are opting for active surveillance or watchful waiting rather than immediate treatment with surgery or radiation, a new study reveals that black men are less likely than white men to adopt an active surveillance strategy for their disease. (2019-05-22)
Liquid biopsy could identify cancer patients at risk of metastatic disease
Analyzing fragments of DNA that are shed by tumors into the bloodstream, could indicate early on whether patients are at risk of their cancer spreading, according to new research presented today. (2019-05-15)
IL-1 inhibitors may reduce radiation-induced vascular damage
Radiation therapy against cancer can increase the risk of cardiovascular disease much later in life, as the radiation causes chronic inflammation of the exposed blood vessels. (2019-05-14)
ASTRO and AUA update joint clinical guidance for radiation therapy after prostatectomy
The American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA) today announced updates to their joint clinical guideline on adjuvant and salvage radiotherapy after prostatectomy in patients with and without evidence of prostate cancer recurrence to include new published research related to adjuvant radiotherapy. (2019-05-01)
EGLN inhibitor protects normal tissue and enables RT in mouse model of pancreatic cancer
Administration of the EGLN inhibitor FG-4592 prior to ablative radiotherapy provided protection against fatal gastrointestinal bleeding and improved survival in a mouse model of unresectable pancreatic cancer. (2019-04-30)
Researchers identify ways to predict and avoid radiotherapy side effects
Latest results from a project to discover what makes a cancer patient more likely to suffer adverse side effects after radiotherapy have shown that a combination of biological markers and certain genetic changes can predict radiation sensitivity. (2019-04-29)
Memory could be better protected in kids with brain tumors if treated with proton therapy
A comparison of three types of radiotherapy for children's brain tumors suggests that a type of proton therapy called pencil beam scanning offers the best hope of preserving cognitive functions. (2019-04-29)
Radiotherapy after chemo may improve survival in patients with advanced Hodgkin's lymphoma
Patients with advanced Hodgkin's lymphoma who have large tumors at the time of diagnosis may benefit from radiotherapy after chemotherapy even when all traces of the cancer appear to have gone, according to late-breaking results presented at the ESTRO 38 conference. (2019-04-28)
Radiotherapy doubles survival for patients with mesothelioma
Mesothelioma patients are twice as likely to survive for two years or longer, if they are treated with a high dose of radiation to the affected side of the trunk, according to research presented at the ESTRO 38 conference. (2019-04-28)
Single dose of targeted radiotherapy is safe and effective for prostate cancer
A single high dose of radiation that can be delivered directly to the tumor within a few minutes is a safe and effective technique for treating men with low-risk prostate cancer, according to a study presented at the ESTRO 38 conference. (2019-04-28)
Early, hormone-driven breast cancer is less likely to recur if treated with radiotherapy
Women with early, low-risk, hormone-driven breast cancer are less likely to have a recurrence of their disease if they have radiotherapy after surgery, as well as anti-hormone treatment, according to results from a trial that has followed 869 women for 10 years. (2019-04-25)
Three studies show how tumors hijack the immune system to resist radiation therapy
Treg cells turn off the immune system. Three recent studies show that targeting tregs may increase the effectiveness of anti-cancer immunotherapies. (2019-04-16)
Some patients with imminently fatal cancer still receive treatment
Patients who died within one month of being newly diagnosed with metastatic cancer in the United States received ineffective surgery, chemotherapy, radiation, and hormonal therapy. (2019-04-15)
High-dose stereotactic body radiotherapy well-tolerated by patients with centrally located lung tumors
Stereotactic body radiotherapy (SBRT), a high-dose, precisely delivered radiotherapy, is considered the standard treatment for patients with medically inoperable, node-negative, non-small cell lung cancer (NSCLC). (2019-04-05)
Combo of virotherapy and radiotherapy shows early promise in patients with esophageal cancer
The experimental oncolytic adenovirus telomelysin (OBP-301) in combination with radiotherapy was safe and showed early clinical efficacy in vulnerable patients with esophageal cancer, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)
Optimizing proton beam therapy with mathematical models
Particle beam therapy, a form of radiotherapy that involves using beams of positively charged particles rather than X-rays, is becoming increasingly popular. (2019-04-02)
Using 3D models to reduce side effects of radiotherapy
The debilitating side effects of radiotherapy could soon be a thing of the past thanks to a breakthrough by University of South Australia (UniSA) and Harvard University researchers. (2019-03-14)
Adding docetaxel-based chemotherapy to standard treatment for high-risk prostate cancer
Researchers theorized that adding adjuvant docetaxel, a cytotoxic chemotherapy drug, to the standard of care RT and long-term AS treatment could potentially improve overall survival and clinical outcomes for men with localized, high-risk prostate cancer. (2019-03-12)
Sperm quality unaffected by one course of chemotherapy for early testicular cancer
Men with early stage testicular cancer can safely receive one course of chemotherapy or radiotherapy after surgery without it having a long-term effect on their sperm count, according to a study published in Annals of Oncology. (2019-02-24)
Hypofractionated RT should be considered new practice standard for men with low risk prostate cancer
Results from the NRG Oncology clinical study NRG-RTOG 0415 determined that a hypofractionated radiotherapy schedule (H-RT), a treatment schedule that delivers a total dose of radiotherapy over a shorter period of time, is not worse than the conventional radiotherapy schedule (C-RT) in terms of bowel, bladder, sexual, and general quality of life (QOL) as well as anxiety and depression for men with low risk prostate cancer. (2019-02-15)
Study finds upsurge in 'active surveillance' for low-risk prostate cancer
Many men with low-risk prostate cancer who most likely previously would have undergone immediate surgery or radiation are now adopting a more conservative 'active surveillance' strategy, according to an analysis of a new federal database by scientists from Dana-Farber Cancer Institute. (2019-02-11)
Shorter course of radiation therapy effective in treating men with prostate cancer
A new UCLA-led study shows that men with low- or intermediate-risk prostate cancer can safely undergo higher doses of radiation over a significantly shorter period of time and still have the same, successful outcomes as from a much longer course of treatment. (2019-02-08)
Electrical activity in prostate cancer cells
Experts from the universities of Bath and Seville have carried out a series of experiments with which, for the first time, they have been able to characterize the normal electrical activity in PC-3 prostate cancer cells in real time, with a resulting low-frequency electrical pattern between 0.1 and 10 Hertz. (2019-02-04)
Important signaling pathway in breast cancer revealed
Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences of the United States of America (PNAS) that a particular signaling pathway in breast-cancer tumors causes cancer cells to divide symmetrically, expanding the tumor. (2019-01-24)
Advances and challenges in precise nanomedicine for intelligent therapy of cancer
The authors demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. (2019-01-16)
New approach may curb treatment-related skin fibrosis in cancer patients
A clinical-scientific team specializing in head-and-neck cancer has identified a way to manipulate metabolism to potentially curb skin fibrosis -- a common side effect of radiotherapy affecting quality of life of cancer survivors. (2019-01-07)
The production of Ac-225
This manuscript attempts to present an overview of availability sources of 225Ac and production methods by which additional supplies might be made available to the community of clinical researchers seeking their application in the treatment of human disease. (2018-12-20)
Some brain tumors may respond to immunotherapy, new study suggests
A new study suggests that a slow-growing brain tumor arising in patients affected by neurofibromatosis type 1 (NF1) may be vulnerable to immunotherapy, which gives the immune system a boost in fighting cancer. (2018-12-10)
Low-dose tamoxifen reduced recurrence and new disease for patients with DCIS, LCIS, and ADH
Treatment with a low dose of tamoxifen (5 mg per day) halved the risk of disease recurrence and new disease for women who had been treated with surgery following a diagnosis of breast intraepithelial neoplasia compared with placebo, and it did not cause more serious adverse events, according to data from the randomized, phase III TAM-01 clinical trial presented at the 2018 San Antonio Breast Cancer Symposium. (2018-12-06)
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