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Current Rheumatoid arthritis News and Events

Current Rheumatoid arthritis News and Events, Rheumatoid arthritis News Articles.
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Better biosensor technology created for stem cells
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders. (2019-11-11)
Penn uncovers dose of medication more likely to put patients with pemphigus into remission
Researchers from Penn compare a lymphoma-dose regimen of rituximab to a rheumatoid arthritis regimen for the treatment of pemphigus. (2019-11-11)
Live zoster vaccine safe and effective for people taking TNF inhibitors
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications (Abstract # 824). (2019-11-09)
Babies exposed to TNFi or tofacitinib in utero experience very few serious infections
A new study found that very few serious infections were seen in children born to mothers with chronic inflammatory diseases who used non-TNFi biologics or tofacitinib during pregnancy compared to children not exposed to these drugs and children exposed to TNFi biologics in utero. (2019-11-09)
Opioid use hospitalization rates increased for patients with common rheumatic diseases
New research findings presented this week at the 2019 ACR/ARP Annual Meeting show an increase in opioid-use disorder (OUD) hospitalizations among patients with five musculoskeletal conditions, trends that healthcare providers, policy makers and patients need to be more aware of to help prevent opioid use disorder-related morbidity and mortality. (2019-11-09)
Ultrasound to guide treatment strategy not beneficial in early RA
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, a treatment strategy guided by ultrasound information use does not appear to provide better treatment decisions in patients with early rheumatoid arthritis. (2019-11-09)
Down syndrome arthropathy diagnosis delayed a year, optimal treatments still unclear
A new study found that patients with Down syndrome arthropathy continue to have an approximate year-long delay in diagnosis from the onset of their symptoms, and that optimal therapy for this condition remains unclear (Abstract # 2722). (2019-11-09)
Psoriasis onset determines if psoriatic arthritis patients develop arthritis or psoriasis first
In a new study presented at the 2019 ACR/ARP Annual Meeting, researchers found the age of psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis. (2019-11-09)
Tocilizumab more effective than Rituximab in RA patients with low B-cell levels
New research discovered that tocilizumab is more effective than rituximab in achieving low disease activity in patients with rheumatoid arthritis whose synovial tissue show a low level of B cell infiltration and did not respond to conventional synthetic disease-modifying anti-rheumatic drugs (conventional synthetic DMARDs) or tumor necrosis factor (TNFi) inhibitors first. (2019-11-09)
Additional medications to treat children with JIA are urgently needed
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, there is a profound ongoing need for additional medications to control the signs and symptoms of juvenile idiopathic arthritis (JIA), despite the availability of several approved biologic disease-modifying antirheumatic drugs (biologics). (2019-11-09)
Children with Down syndrome at increased risk for inflammatory, erosive arthritis
A new study finds that children with Down syndrome are at an increased risk of an associated form of arthritis. (2019-11-09)
ADA2 is a specific biomarker for MAS in systemic JIA
According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA). (2019-11-09)
Methotrexate reduces joint damage progression over placebo in erosive hand OA
According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis, but did significantly reduce the progression of joint damage over placebo and seems to facilitate bone remodeling in these patients. (2019-11-09)
Some people with RA treated with immune checkpoint inhibitors for cancer have flare, most able to continue treatment
A new study found that cancer patients with a pre-existing autoimmune disease receiving immune checkpoint inhibitors as treatment are likely to experience a flare. (2019-11-09)
Biologics offer similar disease activity improvement for elderly & young-onset RA patients
According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, both patients with rheumatoid arthritis whose disease onset occurred at an older age and those whose disease onset occurred earlier in life have similar improvements in clinical disease at 48 weeks after starting biologic disease-modifying antirheumatic drugs, as well as similar drug maintenance and adverse events discontinuation rates. (2019-11-09)
Researchers find potential new target for treatment of inflammatory disease
Researchers led by the University of Birmingham have found a potential new target to treat inflammatory disease. (2019-11-07)
Vitamin D and Omega 3 supplements do not reduce risk of systemic inflammation
An analysis of the VITamin D and OmegA-3 TriaL (VITAL) by investigators at Brigham and Women's Hospital indicates that neither vitamin D nor omega-3s were effective at reducing systemic inflammation. (2019-11-07)
New technology promises improved treatment of inflammatory diseases
A study led by researchers at Washington State University has uncovered a potential new treatment approach for diseases associated with inflammation, including sepsis and stroke. (2019-11-06)
WSU study identifies potential new target for treatment of gout
Researchers at Washington State University Health Sciences Spokane and elsewhere have identified a new therapeutic target for the treatment of gout, a common type of arthritis that causes episodes of painful and stiff joints. (2019-10-29)
Controlling the immune system's brakes to treat cancer, autoimmune disorders
Researchers at St. Jude have revealed the mechanism underlying the activation of regulatory T cells, which could spark new drug development. (2019-10-24)
Anti-arthritis drug also stops tuberculosis bacillus from multiplying in blood stem cells
Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells. (2019-10-23)
Osteoarthritis can increase your risk for social isolation
In a study published in the Journal of the American Geriatrics Society, researchers examined information from the European Project on OSteoArthritis (EPOSA) study. (2019-10-15)
TTUHSC study shows brain mechanisms have potential to block arthritis pain
Because pain is a complex condition, treating it efficiently continues to pose challenge for physicians. (2019-10-10)
Targeting certain rogue T cells prevents and reverses multiple sclerosis in mice
Multiple sclerosis, an autoimmune disorder, is known to be driven by 'helper' T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. (2019-10-04)
S1P molecule regulates dendritic cell localization and vascular integrity in lymph nodes
Researchers found that HEVs, which were deficient for the S1P-transporter Spinster-homologue-2, were unable to attract dendritic cells in order to trigger LTβr-signaling through cell-cell contact with HEVs. (2019-10-01)
Severe silicosis found among fabricators of engineered quartz stone
In this week's Morbidity and Mortality Weekly Report, researchers from California, Colorado, Texas and Washington report 18 cases of severe silicosis, and two fatalities, among young, mostly Hispanic men, who worked at engineered stone fabrication plants. (2019-09-26)
Antibody 'road block' enables fine-tuning for cardiac recovery
A new study published by Vanderbilt mechanobiology researchers details a possible solution for fine-tuning inflammation and cellular activity in cardiac recovery -- thanks to an antibody initially developed for rheumatoid arthritis.  (2019-09-19)
Tumor resistance is promoted by anti-cancer protein
Areas of solid tumors that have limited access to oxygen, a condition called hypoxia, are highly resilient against chemo and radiation therapy. (2019-09-19)
Acute chikungunya infection studied at the molecular level in Brazilian patients
Using a systems biology approach, Brazilian researchers identified several genes that can be explored as therapeutic targets and as biomarkers of predisposition to chronic joint pain. (2019-09-16)
Scientists prove low cost arthritis drug can effectively treat blood cancer sufferers
A simple arthritis drug could be an effective, low cost solution to treat patients with blood cancers such as polycythemia vera (PV) and essential thrombocythemia (ET), a breakthrough study by the University of Sheffield has shown. (2019-09-16)
Patient survey highlights challenges for the 1 in 4 living with rheumatic disease
Americans living with rheumatic disease face significant healthcare challenges, according to a national patient survey released this week by the American College of Rheumatology and its Simple Tasks™ public awareness campaign. (2019-09-13)
Humans more unique than expected when it comes to digesting fatty meals
People have very individualized inflammatory responses to eating a high-fat meal. (2019-09-12)
New review highlights benefits of plant-based diet for rheumatoid arthritis
A plant-based diet may alleviate painful symptoms associated with rheumatoid arthritis (RA), according to a new review published in the journal Frontiers in Nutrition. (2019-09-12)
Rheumatology leaders and patients go to Capitol Hill to advocate
Physicians and health professionals from the American College of Rheumatology (ACR) along with rheumatology patients gathered on Capitol Hill this week for the annual Advocates for Arthritis event to urge lawmakers to take action on a range of policy issues affecting patient access to rheumatology care. (2019-09-10)
Biomarker identified for early beta cell death in Type 1 diabetes
Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. (2019-09-06)
Modifiable risk factors contribute to gout
Elevated urate in the blood (hyperuricemia) is a precursor of gout, which is the most common form of inflammatory arthritis worldwide. (2019-09-05)
'Tiny fat bubbles' can boost immunity, calm disease
People living with inflammatory autoimmune disease could benefit from an 'immune system reboot', and researchers have isolated specific cells to target. (2019-09-05)
Arthritis-causing virus hides in body for months after infection
Researchers at Washington University School of Medicine in St. Louis have developed a way to fluorescently tag cells infected with chikungunya virus. (2019-08-29)
University of Alberta researchers discover new biomarker for rare autoimmune disease
University of Alberta researchers have identified a unique biological marker that can be used to identify the presence of the rare autoimmune disease myasthenia gravis, predict the course of the disease and identify new, personalized treatments. (2019-08-29)
Genetic risk is associated with differences in gut microbiome
Children with a high genetic risk of developing type 1 diabetes have different gut microbiomes than children with a low risk, according to a new study from Linköping University in Sweden and the University of Florida in the US. (2019-08-19)
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