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Current RNA News and Events, RNA News Articles.
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A cancer mystery of more than 40 years ago is solved thanks to epigenetics
In an article that was just published in Proceedings of the National Academy of Sciences (PNAS) by the group of Dr. (2020-08-12)
Origins of life: Chemical evolution in a tiny Gulf Stream
Chemical reactions driven by the geological conditions on the early Earth might have led to the prebiotic evolution of self-replicating molecules. (2020-08-07)
Scientists use CRISPR to knock down gene messages early in development
Researchers at the Stowers Institute for Medical Research in Kansas City, Missouri, and the Andalusian Center of Developmental Biology at Pablo de Olavide University in Seville, Spain, have harnessed the technology to target gene messages (messenger RNA) involved in early vertebrate development. (2020-08-07)
Scientists discover new concept of bacterial gene regulation
Microbiologist Prof. Kai Papenfort and his team at Friedrich Schiller University Jena (Germany) discovered a new mechanism of autoregulation during gene expression that relies on small regulatory ribonucleic acids (sRNAs) and the major endoribonuclease RNase E. (2020-08-06)
Unveiled: A channel SARS-CoV-2 may use to proceed with viral replication in the host cell
By visualizing coronavirus replication in an infected host cell, researchers may have answered a long-standing question about how newly synthesized coronavirus components are able to be incorporated into fully infectious viruses. (2020-08-06)
Projecting early molecular signatures of AD through the convergence study of Omics and AI
Dr. Cheon Mookyung of KBRI published the research results in an international academic journal of computational biology. (2020-08-05)
Cold-sensitive staphylococci reveal a weakness
A team from the University of Geneva has identified a new mechanism involved in the membrane synthesis of Staphylococcus aureus. (2020-08-03)
AI & single-cell genomics
The study of cellular dynamics is crucial to understand how cells develop and how diseases progress. (2020-08-03)
In defence mode: this is how Zika virus protects key parts of its genome
To fight viruses, cells can deploy defence enzymes that progressively destroy viral genome. (2020-07-30)
Researchers describe structure of SARS-CoV-2 proteins suitable for design of new drugs
Group of researchers at IOCB Prague determined and analyzed the precise structure of the Nsp16 and Nsp10 protein complex of the new coronavirus SARS-CoV-2. (2020-07-30)
Adverse effects from cancer drug trials explained
Certain type of cancer drugs that promote the death of cells can actually be harmful if combined with other treatments that damage our DNA, RNA or proteins, researchers have found. (2020-07-29)
Bringing RNA into genomics
By studying RNA-binding proteins, a research consortium known as ENCODE (Encyclopedia of DNA Elements) has identified genomic sites that appear to code for RNA molecules that influence gene expression. (2020-07-29)
UC San Diego scientists part of special package of studies describing human genome
Researchers at UC San Diego School of Medicine are among the contributors to a package of 10 studies in the journal Nature, describing the latest results from the ongoing Encyclopedia of DNA Elements project, a worldwide effort led by the NIH to understand how the human genome functions. (2020-07-29)
The amazing travels of small RNAs
Biologists have known for some time that RNA interference can silence genes in far-?off cells. (2020-07-28)
RNA biology provides the key to cell identity and health
Two papers in Genome Research by the FANTOM Consortium have provided new insights into the core regulatory networks governing cell types in different vertebrate species, and the role of RNA as regulators of cell function and identity. (2020-07-27)
Alternative amplification technique could speed up SARS-CoV-2 testing
An alternative amplification technique to detect SARS-CoV-2 RNA could offer a way to rapidly test large numbers of people for COVID-19, although the technique is not as sensitive as quantitative RT-PCR, the current standard method for COVID-19 testing. (2020-07-27)
Coronavirus makes changes that cause cells not to recognize it
The novel coronavirus changes the appearance of its messenger RNA cap to trick the host cell into not recognizing it is foreign, according to a study reported by researchers from UT Health San Antonio. (2020-07-24)
SARS-CoV-2 infection of non-neuronal cells, not neurons, may drive loss of smell in patients with COVID-19
A new study of human olfactory cells has revealed that viral invasion of supportive cells in the nasal cavity might be driving the loss of smell seen in some patients with COVID-19. (2020-07-24)
PolyA-miner assesses the effect of alternative polyadenylation on gene expression
Meet PolyA-miner, a new computational tool that enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease. (2020-07-23)
Junk DNA might be really, really useful for biocomputing
When you don't understand how things work, it's not unusual to think of them as just plain old junk. (2020-07-22)
UNH researchers discover new pathways that could help treat RNA viruses
Researchers at the University of New Hampshire have identified new pathways in an RNA-based virus where inhibitors, like medical treatments, unbind. (2020-07-22)
Novel 'on-off' switch discovered in plant defenses
Researchers investigating the ways that plants protect themselves--from insects to pathogens--have discovered an ''on-off'' switch that controls plant defensive mechanisms. (2020-07-22)
Comprehensive description of the human tissue virome in healthy individuals
This study is the first comprehensive investigation of the human virome in a variety of tissues in healthy individuals through meta-transcriptomic analysis. (2020-07-21)
Silver-plated gold nanostars detect early cancer biomarkers
Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification. (2020-07-21)
COVID-19 replicating RNA vaccine has robust response in nonhuman primates
A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. (2020-07-20)
Advanced Cryo-EM reveals viral RNA replication complex structure in stunning detail
For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses. (2020-07-20)
Neural vulnerability in Huntington's disease tied to release of mitochondrial RNA
A uniquely comprehensive survey of gene expression by cell type in humans and mice revealed several deficits affecting the most vulnerable neurons in Huntigton's disease. (2020-07-17)
Genetic editing milestone in mouse model of Rett Syndrome
A genomic error that causes Rett Syndrome, a serious lifelong neurological disorder, can be corrected in the brains of mice by rewriting the genetic instructions carried by the RNA. (2020-07-15)
University of Toronto scientists uncover key process in the manufacture of ribosomes and proteins
Researchers at the University of Toronto have shown that an enzyme called RNA polymerase (Pol) II drives generation of the building blocks of ribosomes, the molecular machines that manufacture all proteins in cells based on the genetic code. (2020-07-15)
Elderly Alzheimer's patients are more vulnerable to COVID-19 infection
It is the first study to highlight the vulnerability of Alzheimer's patients to the novel coronavirus (SARS-CoV-2) and is expected to be applied to infection diagnosis and prevention (2020-07-15)
Study: RNA repair shows promise in reversing mutations underlying a neurological disorder
Scientists successfully edited RNA in a living animal in such a way that the repaired RNA then corrected a mutation in a protein that gives rise to a debilitating neurological disorder in people known as Rett syndrome. (2020-07-14)
Molecular "tails" are secret ingredient for gene activation
Researchers in the lab of Caltech's Paul Sternberg discover how diverse forms of life are able to use the same cellular machinery for DNA transcription. (2020-07-14)
Listeria protein provides a CRISPR 'kill switch'
A single protein derived from a common strain of bacteria found in the soil will offer scientists a more precise way to edit RNA. (2020-07-13)
Single-cell RNA sequencing outlines the immune landscape of severe COVID-19
A new single-cell RNA sequencing analysis of more than 59,000 cells from three different patient cohorts provides a detailed look at patients' immune responses to severe cases of COVID-19. (2020-07-10)
Enhancing chemotherapy by RNA interference - BIO Integration
Enhancing Chemotherapy by RNA Interference - BIO Integration https://doi.org/10.15212/bioi-2020-0003 Announcing a new article publication for BIO Integration journal. (2020-07-08)
How to precisely edit mitochondrial DNA
A gene editing tool based on a bacterial toxin can make precise changes to mitochondrial DNA inside cells. (2020-07-08)
New clues to lung-scarring disease may aid treatment
Scientists at Vanderbilt University Medical Center (VUMC) and the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, have discovered previously unreported genetic and cellular changes that occur in the lungs of people with pulmonary fibrosis (PF). (2020-07-08)
Circular RNA makes fruit flies live longer
The molecule influences the insulin signalling pathway and thus prolongs life (2020-07-07)
Gut Piezo1 regulates gut and bone homeostasis via RNA sensing.
Gut enterochromaffin cells regulate gut and bone homeostasis via serotonin production. (2020-07-07)
RNA key in helping stem cells know what to become
If every cell has the same genetic blueprint, why does an eye cell look and act so differently than a brain cell or skin cell? (2020-07-07)
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