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Current Rna News and Events

Current Rna News and Events, Rna News Articles.
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Origin of life - A prebiotic route to DNA
DNA, the hereditary material, may have appeared on Earth earlier than has been assumed hitherto. (2019-06-18)
How the cell protects itself
The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. (2019-06-12)
DNA base editing induces substantial off-target RNA mutations
Researchers from Dr. YANG Hui's Lab at the Institute of Neuroscience of the Chinese Academy of Sciences (CAS), and collaborators from the CAS-MPG Partner Institute for Computational Biology of CAS and Sichuan University demonstrated that DNA base editors generated tens of thousands of off-target RNA single nucleotide variants (SNVs) and these off-target SNVs could be eliminated by introducing point mutations to the deaminases. (2019-06-10)
Dynamics of key viral attack strategy visible for first time
For the first time, Colorado State University scientists Tim Stasevich and Brian Munsky have developed detailed imaging technology and computational analyses to visualize, quantify and understand frameshifting mechanisms at the level of single molecules in living cells. (2019-06-06)
Normal tissues not so normal, but instead mosaics of mutated cells
Normal cell populations may not be as 'normal' as once thought; rather, tissues contain lineages of mutational mosaics developed over a lifetime, according to a comprehensive RNA sequence analysis of more than 6,700 samples across 29 different human tissues. (2019-06-06)
Researchers spot mutations that crop up in normal cells as we age
Cell division is not perfect. As we get older, mutations often appear in genes in normal cells. (2019-06-06)
To curb infection, bacteria direct their defenses against themselves
To fight off invading viruses, bacteria have evolved a slew of creative defense tactics. (2019-05-30)
Genetic analysis of cannabis is here
Research from Washington State University could provide government regulators with powerful new tools for addressing a bevy of commercial claims and other concerns as non-medical marijuana, hemp and CBD products become more commonplace. (2019-05-29)
Lost in translation: The medium is the message for a healthy heartbeat
Researchers at the Fralin Biomedical Research Institute at Virginia Tech Carilion have revealed how a genetic message to produce healthy heart tissue is altered in the body during stress and aging to contribute to sudden cardiac death. (2019-05-28)
Cell division requires a balanced level of non-coding RNA for chromosome stability
Assistant Professor Dr Karen Wing Yee Yuen and Postdoctoral Fellow Dr Yick Hin Ling from the School of Biological Sciences, University of Hong Kong (HKU), discovered that centromeric DNA is used as a template to produce a non-protein coding, centromeric RNA (ribonucleic acid), that is essential for chromosome stability. (2019-05-22)
Structural and functional mechanisms of a new class of bacterial sigma/anti-sigma factors revealed
Prof. FENG Yingang and his colleagues from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences recently revealed the structural and functional mechanism of the SigI/RsgI factors from C. thermocellum. (2019-05-19)
Research reveals insulin-producing beta cells may change function in diabetes
A revolutionary new study using only materials derived from humans has revealed that insulin-producing beta cells can change their function in diabetes -- and that this change may be reversible. (2019-05-17)
Breakthrough technique for studying gene expression takes root in plants
An open-source RNA analysis platform has been successfully used on plant cells for the first time -- a breakthrough that could herald a new era of fundamental research and bolster efforts to engineer more efficient food and biofuel crops. (2019-05-16)
How potatoes could become sun worshippers
If the temperature is too high, potato plants form significantly lower numbers of tubers. (2019-05-14)
How mutations lead to neurodegenerative disease
Scientists have discovered how mutations in DNA can cause neurodegenerative disease. (2019-05-13)
Catch a virus by its tail
At a glance: Research uncovers key mechanism that allows some of the deadliest human RNA viruses to orchestrate the precise copying of the individual pieces of their viral genome and replicate. (2019-05-13)
Seed abortion and the role of RNA Pol IV in seed development
In this newly released article in The Plant Cell, researchers find that in Arabidopsis plants, the abortion of seeds with extra genomes is caused by the enzyme RNA Pol IV and the RNA-directed DNA methylation pathway, a major gene-silencing pathway in plants. (2019-05-07)
New computational tool enables powerful molecular analysis of biomedical tissue samples
Researchers at the Stanford University School of Medicine invented a computational technique called CIBERSORTx that can analyze the RNA of individual cells taken from whole-tissue samples or data sets. (2019-05-06)
Shambhala helps understand the 'decoding' of RNA
Scientists at Sechenov University, together with their Russian and American colleagues, developed the tool named Shambhala, which can process the 'decoding' of RNA obtained on different equipment to make them suitable for comparison and further study. (2019-05-04)
Making the invisible visible: New method opens unexplored realms for liquid biopsies
A new approach to RNA sequencing reveals thousands of previously inaccessible RNA fragments in blood plasma that might serve as disease- and organ-specific biomarkers (2019-05-03)
RIT professor develops microfluidic device to better detect Ebola virus
A faculty-researcher at Rochester Institute of technology has developed a prototype micro device with bio-sensors that can detect the deadly Ebola virus. (2019-05-03)
Cancer cells have a problem with junk RNA that makes them vulnerable
The important role of the ADAR enzyme and junk RNA in cancer cells opens an entirely new playbook for the treatment of tumors, one that is focused on RNA rather than DNA. (2019-05-03)
Discovery of RNA transfer through royal jelly could aid development of honey bee vaccines
Researchers have discovered that honey bees are able to share immunity with other bees and to their offspring in a hive by transmitting RNA 'vaccines' through royal jelly and worker jelly. (2019-05-02)
Chemical modifiers tag-team to regulate essential mechanism of life
For decades, scientists thought that one modification, phosphorylation, ran the show. (2019-05-02)
Screening for genes to improve protein production in yeast
By silencing genes, researchers have managed to increase protein production in yeast significantly. (2019-04-26)
Structure and degradation of circular RNAs regulate PKR activation in innate immunity
In a study published in Cell, a team led by Dr. (2019-04-25)
WINTHER trial results
Published in Nature Medicine, results of WINTHER, the first study pioneered by the WIN Consortium -- Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial -- shows that RNA profiling together with DNA testing matches more patients with advanced cancer to personalized therapies than DNA profiling for tumor mutations alone. (2019-04-25)
A new clue in the mystery of ALS, frontotemporal dementia
Michigan Medicine (University of Michigan) researchers identify a potential therapeutic target for neurodegenerative conditions ALS and frontotemporal dementia, using animal models. (2019-04-23)
Overlooked molecular machine in cell nucleus may hold key to treating aggressive leukemia
Many people fighting a very aggressive form of acute myeloid leukemia (AML) don't survive more than five years. (2019-04-22)
Plants are also stressed out
What will a three-degree-warmer world look like? When experiencing stress or damage from various sources, plants use chloroplast-to-nucleus communication to regulate gene expression and help them cope. (2019-04-19)
BRB-seq: The quick and cheaper future of RNA sequencing
EPFL bioengineers have developed a new method for Bulk RNA Sequencing that combines the multiplexing-driven cost-effectiveness of a single-cell RNA-seq workflow with the performance of a bulk RNA-seq procedure. (2019-04-18)
Barrow researcher discovers critical RNA processing aberrations
Research by a Barrow Neurological Center scientist on mechanisms of dysfunctional RNA processing in ALS and frontaltemporal dementia (FTD) was published in the April issue of Acta Neuropathologica. (2019-04-18)
CRISPR base editors can induce wide-ranging off-target RNA edits
A Massachusetts General Hospital research team reports that several of the recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target effects in RNA, extending beyond the targeted DNA. (2019-04-17)
Large multi-ethnic genome-wide association study of asthma identifies novel associations
A large, multi-ethnic genome-wide association study (GWAS) of asthma identified novel associations with potential relevance for asthma susceptibility in older adults of diverse racial backgrounds. (2019-04-16)
What happens in the bodies of ALS patients?
Lara Marrone and Jared Sterneckert from the Centre for Regenerative Therapies Dresden (CRTD) at Technische Universität Dresden (TUD), together with collaborating scientists from Germany, Italy, the Netherlands, and the USA, have now discovered that interactions between RNA-binding proteins are more critical to ALS pathogenesis than previously thought. (2019-04-15)
RNA transport in neurons -- Staufen2 detects its target transcripts in a complex manner
A team of scientists from Helmholtz Zentrum M√ľnchen and the University of Ulm has discovered that the neuronal transport factor Staufen2 scans and binds to its target transcripts in a much more complex manner than previously thought. (2019-04-15)
Scientists get sly, use deception to fight cancer
In recent years, it's become clear that RNA-binding proteins play a major role in cancer growth. (2019-04-15)
Engineering 'hairpins' increases CRISPR accuracy
Biomedical engineers at Duke University have developed a method for improving the accuracy of the CRISPR genome editing technology by an average of 50-fold. (2019-04-15)
US and Japanese researchers identify how liver cells protect against viral attacks
Researchers in Chapel Hill, N.C., and Tokyo have discovered a mechanism by which liver cells intrinsic resistance to diverse RNA viruses is regulated. (2019-04-15)
Earliest life may have arisen in ponds, not oceans
Primitive ponds may have provided a suitable environment for brewing up Earth's first life forms, more so than oceans, a new MIT study finds. (2019-04-12)
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