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Current Spinal muscular atrophy News and Events

Current Spinal muscular atrophy News and Events, Spinal muscular atrophy News Articles.
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How neuromuscular connections are maintained after nerve lesions
After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. (2019-07-25)
One or the other: Why strength training might come at the expense of endurance muscles
The neurotransmitter brain-derived neurotrophic factor (BDNF) acts in the muscle, so that during strength training endurance muscle fiber number is decreased. (2019-07-25)
Viral HIV vaccine gives durable protection against 'death star' strain
Efforts to develop an effective HIV vaccine have repeatedly stumbled on one tough research strain, SIVmac239. (2019-07-24)
Boosting the discovery of new drugs to treat spinal cord injuries using zebrafish
A research team led by Leonor Sa├║de, Principal Investigator at Instituto de Medicina Molecular, in partnership with the company Technophage, SA, has designed a simple and efficient platform that uses zebrafish to discover and identify new drugs to treat spinal cord lesions. (2019-07-19)
New research identifies gene that hides cancer cells from immunotherapy
A team at Fred Hutchinson Cancer Research Center has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients. (2019-07-18)
Drinking red wine on the red planet
BIDMC researchers report that a daily moderate dose of resveratrol significantly preserved muscle function and mitigated muscle atrophy in an animal model mimicking Mars' partial gravity. (2019-07-18)
Early mammal fossil reveals the evolutionary origins of having a loose tongue
Our highly mobile mammalian tongues, which allow us to swallow chewed food and suckle milk as babies, may have evolutionary origins in some of our most early mammalioform ancestors, according to a new study, which finds remarkably complex and modern mammal-like hyoid bones in a newly discovered 165-million-year-old mammaliaform species. (2019-07-18)
Study pinpoints cell types affected in brains of multiple sclerosis patients
Scientists have discovered that a specific brain cell known as a 'projection neuron' has a central role to play in the brain changes seen in multiple sclerosis (MS). (2019-07-17)
Researchers describe new ALS biomarkers, potential new drug targets
Researchers at the University of Illinois at Chicago have described unique populations of neurons and associated cells in the spinal cords of patients who died of ALS. (2019-07-15)
Despite long-term treatment, HIV persists in spinal fluid, linked to cognition problems
Even after nearly a decade of strict HIV treatment, cells sheltering the virus could be found in the cerebrospinal fluid of half of participants in a national clinical trial of people living with HIV. (2019-07-15)
HIV may affect the brain despite ongoing antiretroviral therapy
HIV-positive patients are living longer thanks to combination antiretroviral therapy (cART), but the virus can remain in some tissues, preventing a total cure. (2019-07-15)
Thwack! Insects feel chronic pain after injury
Scientists have known insects experience something like pain since 2003, but new research published today from Associate Professor Greg Neely and colleagues at the University of Sydney proves for the first time that insects also experience chronic pain that lasts long after an initial injury has healed. (2019-07-12)
An itch to scratch: NCATS, NIDCR scientists identify potential approach to chronic problem
While scientists have some clues to the causes of troubling chronic itch, effective therapies have been elusive. (2019-07-12)
An 'EpiPen' for spinal cord injuries
An injection of nanoparticles can prevent the body's immune system from overreacting to trauma, potentially preventing some spinal cord injuries from resulting in paralysis. (2019-07-11)
Mathematical model explores daily rhythms in pain sensitivity
A new computational model successfully predicts how daily pain sensitivity rhythms affect pain processing, both in healthy adults and in people with neuropathic pain. (2019-07-11)
Keeping a cell's powerhouse in shape
A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. (2019-07-10)
New analysis shows drug slows down respiratory decline
Duchenne muscular dystrophy occurs in boys and is characterized by progressive muscle degeneration and weakness leading to a decline in respiratory function. (2019-07-09)
Discovery reveals prolific ability of Schwann cells to generate myelin
Scientists have discovered that a special type of cell is much more prolific in generating a protective sheath covering nerve fibers than previously believed. (2019-07-05)
New imaging molecule captures brain changes tied to progressive multiple sclerosis
'There's more to multiple sclerosis than white matter lesions,' said corresponding author Tarun Singhal, M.D., a neurologist at the Ann Romney Center for Neurologic Diseases at the Brigham. (2019-07-01)
Sense of smell, pollution and neurological disease connection explored
A consensus is building that air pollution can cause neurological diseases such as Alzheimer's disease and Parkinson's disease, but how fine, sooty particles cause problems in the brain is still an unanswered question. (2019-07-01)
Copper compound shows further potential as therapy for slowing ALS
A compound with potential as a treatment for ALS has gained further promise in a new study that showed it improved the condition of mice whose motor neurons had been damaged by an environmental toxin known to cause features of ALS. (2019-07-01)
Protein offers protection against nerve degeneration in ALS model
Increasing the levels of the anti-aging protein hormone Klotho improves the neurological deficits and prolongs life span in an experimental model with Amyotrophic Lateral Sclerosis (ALS). (2019-06-27)
Researchers study healthy ALS neurons as way to understand resistance to the disease
Scientists have developed a stem-cell-based modeling system that identifies how some neurons are resistant to ALS -- a breakthrough that offers potential for battling neurodegeneration. (2019-06-25)
New therapy promotes vascular repair following stroke
Following a stroke, antibodies that inhibit the signaling molecule Nogo-A can help repair blood vessels in the affected brain regions. (2019-06-24)
One step closer to chronic pain relief
While effective drugs against chronic pain are not just around the corner, researchers from Aarhus University, Denmark, have succeeded in identifying a protein as a future potential target for medicinal drugs. (2019-06-20)
Drug boosts growth in youngsters with most common form of dwarfism, new study finds
A drug that helps regulate bone development has boosted growth rates in children with achondroplasia -- the most common type of dwarfism -- in a trial by Melbourne's Murdoch Children's Research Institute. (2019-06-18)
Researchers identify potential modifier genes in patients with charcot-marie-tooth disease
Charcot-Marie-Tooth (CMT) disease is the most common inherited neurological disorder affecting peripheral motor and/or sensory nerves in humans. (2019-06-18)
Schizophrenia: Adolescence is the game-changer
Schizophrenia may be related to the deletion syndrome. However, not everyone who has the syndrome necessarily develops psychotic symptoms. (2019-06-17)
The evolution of puppy dog eyes
Dogs have evolved new muscles around the eyes to better communicate with humans. (2019-06-17)
Researchers' discovery could lead to improved therapies for duchenne muscular dystrophy
Researchers found that the protein sarcospan can play a major role in combating heart failure in patients with Duchenne muscular dystrophy. (2019-06-14)
UTMB researchers learned how to better combat muscle loss during space flights
A new study from The University of Texas Medical Branch at Galveston has further documented how muscles are affected by reduced gravity conditions during space flight missions and uncovered how exercise and hormone treatments can be tailored to minimize muscle loss for individual space travelers. (2019-06-13)
Promising treatment for shoulder pain in wheelchair users with spinal cord injury
A New Jersey team of researchers has reported the first case of successful, long-term relief of chronic refractory shoulder pain in a wheelchair user with spinal cord injury following a single injection of autologous, micro-fragmented adipose tissue. (2019-06-12)
Scholars investigate how mirror activity works
A team of researchers from Germany and Russia, including Vadim Nikulin from the Higher School of Economics, have demonstrated that long contraction of muscles in one hand increases involuntary reaction of the other one. (2019-06-07)
Worm study sparks hope for slowing muscle decline
Muscle decline caused by ageing and certain diseases could be dramatically slowed by stopping a chain reaction that damages cells, new research shows. (2019-06-07)
Alzheimer's disease protein links plaques to cell death in mice
A new protein involved in Alzheimer's disease (AD) has been identified by researchers at the RIKEN Center for Brain Science (CBS). (2019-06-06)
Losing muscle to fat: misdirected fate of a multipotent stem cell drives LGMD2B
The sudden appearance of clinical symptoms in limb-girdle muscular dystrophy type 2B is due to a unique extracellular environment in which a specific membrane repair protein coaxes fibro/adipogenic precursors to first proliferate and then differentiate into fatty tissue, rather than play their normal role of helping the muscle fibers repair. (2019-06-03)
Lithium boosts muscle strength in mice with rare muscular dystrophy
Researchers at Washington University School of Medicine in St. Louis have found that lithium improves muscle size and strength in mice with a rare form of muscular dystrophy that causes weakness in the shoulders and hips. (2019-06-03)
Genomics of Isle Royale wolves reveal impacts of inbreeding
A new paper explores the genetic signatures of a pair of wolves isolated on Isle Royale, a remote national park in Lake Superior. (2019-05-29)
Microbes on explanted pedicle screws: Possible cause of spinal implant failure
In this paper, the authors demonstrate a significant association between pedicle screw loosening and the presence of low-virulent pathogens on spinal implants. (2019-05-28)
UC Davis study shows temperature alters developing nervous system in frogs
A UC Davis study that compared the effects of cold and warm temperatures on the development of frog eggs into larvae found that environmental temperature significantly changes how the nervous system develops. (2019-05-23)
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