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Current Squamous cell carcinoma News and Events

Current Squamous cell carcinoma News and Events, Squamous cell carcinoma News Articles.
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Immunotherapy is beneficial in gastric and oesophageal cancers, studies show
New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and oesophageal cancers who currently have poor survival. (2020-09-21)
New first-line treatment option for metastatic kidney cancer
The results of the phase 3 CheckMate 9ER trial have provided a new first-line treatment option for patients with metastatic kidney cancer. (2020-09-19)
Immunotherapy combination improves outcomes in advanced kidney cancer
An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. (2020-09-19)
Immunotherapy improves survival in advanced bladder cancer patients
An immunotherapy drug called 'avelumab' has been shown to significantly improve survival in patients with the most common type of bladder cancer, according to results from a phase III clinical trial led by Queen Mary University of London and Barts Cancer Centre, UK. (2020-09-18)
Signalling research waves red flag for commercial drug target candidate
Researchers at the Babraham Institute, Cambridge, UK, have used their understanding of cellular signalling to highlight a pitfall in an emerging treatment for cancer and inflammation. (2020-09-15)
Mayo Clinic and TGen ID potential targets for the most-deadly form of pancreatic cancer
In what is believed to be the most comprehensive analysis of adenosquamous cancer of the pancreas (ASCP), the Mayo Clinic and TGen team identified, in preclinical models, therapeutic targets for this extremely fast-moving and deadly form of pancreatic cancer, and identified already available cancer inhibitors originally designed for other types of cancer, according to a study published today in the journal Cancer Research. (2020-09-14)
Veterinary college team IDs gene that drives ovarian cancer
scientists at the College of Veterinary Medicine have collaborated on a study that pinpoints which specific genes drive - or delay - high-grade serious ovarian carcinoma. (2020-09-11)
Novel discovery challenges a current kidney cancer paradigm
Newly published research has reversed our understanding of an aspect of kidney tumor growth. (2020-09-11)
Stem cell function may explain higher colon cancer rate in males
In research recently published in Stem Cell Reports, Jingxin Li (ljingxin@sdu.edu.cn), Dawei Chen (dawei.chen@uliege.be) and colleagues found that androgen levels can regulate intestinal stem cell proliferation, a new potential link between androgen levels and colon cancer. (2020-09-10)
Chemotherapy drug more effective when combined with microbubbles
Hepatocellular carcinoma is usually treated by blocking the flow of blood to the tumor to induce cancer cell death, but the common treatment, transarterial chemoembolization, is invasive and too imprecise to be a local drug delivery method. (2020-09-08)
Oncotarget: GATA3 and APOBEC3B are prognostic markers in adrenocortical carcinoma
The cover for issue 36 of Oncotarget features Figure 7, 'Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model,' by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood. (2020-09-08)
Hair dye and cancer risk: Largest study yet
Studies have indicated that people who dye their hair regularly may have a higher risk of cancer, especially bladder cancer and breast cancer. (2020-09-03)
How do tumor cells divide in the crowd?
Scientists led by Dr. Elisabeth Fischer-Friedrich, group leader at the Excellence Cluster Physics of Life (PoL) and the Biotechnology Center TU Dresden (BIOTEC) studied how cancer cells are able to divide in a crowded tumor tissue and connected it to the hallmark of cancer progression and metastasis, the epithelial-mesenchymal transition (EMT). (2020-09-02)
How mechanical forces nudge tumors toward malignancy
Researchers studying two forms of skin cancer identified a long-overlooked factor determining why some tumors are more likely to metastasize than others: the physical properties of the tissue in which the cancer originates. (2020-09-02)
Blood marker may reduce cancer burden
Researchers at Flinders University are expanding work on a promising blood test model to help predict or diagnose head and neck cancer, a difficult cancer to pick up early and treat. (2020-09-01)
New insights into mechanism of therapy to reduce liver fat and prevent fibrosis
A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease. (2020-08-26)
New treatment possibilities for young women diagnosed with rare form of ovarian cancer
A recent finding by researchers at the BC Cancer Research Institute and the University of British Columbia (UBC) may offer a new treatment possibility for people diagnosed with a rare and aggressive form of ovarian cancer. (2020-08-26)
A new method for in vivo plant cell imaging with SNAP-tag proteins
A new method for visualizing in vivo protein dynamics in plant cells has been developed by Nagoya University scientists, offering an important step forward in plant cell fluorescent imaging. (2020-08-21)
Robotic surgery may improve outcomes in mouth and throat cancer
Robotic surgery for patients with early stage, oropharyngeal squamous cell cancer is associated with improved health outcomes, including better long-term survival, according to a Cedars-Sinai study published Thursday in JAMA Oncology. (2020-08-20)
International team identifies a new regulatory pathway in bladder cancer
GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma. (2020-08-20)
Antibiotic overuse reduces bladder cancer survival rates
The overprescribing of antibiotics is reducing survival rates in patients with urothelial carcinoma and it needs to be stopped to avoid the serious risk posed by resitant bacterial infections, according to a new medical study. (2020-08-16)
No increased skin cancer risk with topical immunosuppressant ointments
Two topical immunosuppressant medications commonly prescribed to treat skin conditions do not appear to increase the risk for the most common forms of skin cancer, despite package label warnings to the contrary. (2020-08-12)
Addition of sintilimab to pemetrexed and platinum improved progression-free survival
The interim analysis of ORIENT-11, a phase III double-blind randomized trial has shown a nearly two-fold increase in progression-free survival with addition of sintilimab to chemotherapy in patients with advanced or metastatic non-squamous non-small cell lung cancer without EGFR or ALK genomic aberrations, according to research data presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium. (2020-08-08)
Surgical delays for very early stage breast cancer not tied to worse survival outcomes
Retrospective analysis of patients treated between 2010 and 2016 found that delays were associated with a small increase in pathological upstaging for 'stage zero' breast cancer but did not impact overall survival. (2020-08-06)
Effect of gadolinium-based contrast agent on breast diffusion-tensor imaging
An ''Original Research'' article published in ARRS' American Journal of Roentgenology (AJR) concluded that the accuracy of breast cancer diagnosis via diffusion-tensor imaging (DTI) was equivalent both before and after the administration of a gadolinium-based contrast agent (GBCA), despite a value change in DTI parameters. (2020-08-06)
New insight into the evolution of complex life on Earth
A novel connection between primordial organisms and complex life has been discovered, as new evidence sheds light on the evolutionary origins of the cell division process that is fundamental to complex life on Earth. (2020-08-06)
CUNY ISPH study sheds new light on how ovarian cancer grows and evolves
In a paper published in the journal Cancer Research, professor Levi Waldron, post-doctoral fellow Ludwig Geistlinger, and colleagues at the Institute for Implementation Science in Population Health (ISPH) at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH) provide new insights into how ovarian cancer grows and evolves within a person. (2020-08-05)
Assembly within the tumor center
Number of macrophages in tumor tissue enables prognosis of lung tumor progression. (2020-08-04)
The wrong track: How papillomaviruses trick the immune system
Specific antibodies protect us against viral infections - or do they not? (2020-08-04)
Precision medicine identifies key recurring mutation in head and neck cancers
Researchers at UC San Diego School of Medicine and Moores Cancer Center report that an investigational drug candidate called tipifarnib showed promise in treating key recurring mutation in head and neck cancers. (2020-07-30)
Duke-NUS: Cancer mutations caused by bacterial toxin preventable
Reports show that cancer is the second leading cause of death globally. (2020-07-27)
Researchers ID new target in drive to improve immunotherapy for cancer
UCLA researchers have identified a potential new combination therapy to treat advanced head and neck squamous cell carcinoma, the most common type of head and neck cancer. (2020-07-21)
Virginia Tech researchers discover that mouth bacterium may cause colon cancer to spread
Virginia Tech researchers have discovered that one of these common bacteria can leave the mouth and potentially cause existing cancer cells in other parts of the body to spread. (2020-07-21)
Perspective: T cell responses to COVID-19 are a crucial target for research
While early research on the adaptive immune response to COVID-19 primarily looked at antibodies, more information is now emerging on how T cells react to the SARS-CoV-2 virus - addressing a crucial knowledge gap, say Daniel Altmann and Rosemary Boyton in a new Perspective. (2020-07-17)
Oncotarget: Tumor markers for carcinoma identified by imaging mass spectrometry
Volume 11, Issue 28 of Oncotarget features 'Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry' by Schmidt et, al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples. (2020-07-14)
Oncotarget: The Golgi protein TMEM165 controls migration/invasion for carcinoma
The cover for issue 28 of Oncotarget features Figure 5, 'TMEM165 expression levels alters N-linked glycosylation,' by Murali, et al., and reported that the TMEM165 protein was not detected in non-malignant matched breast tissues and was detected in invasive ductal breast carcinoma tissues by mass spectrometry. (2020-07-14)
A 3D biofabricated cutaneous squamous cell carcinoma tissue model
The cover for issue 27 of Oncotarget features Figure 4, ''(A) Bimodal imaging examples of control and treated tumors (red) before and after the treatment period,'' by Browning, et al. and reported that the authors developed a 3-dimensional bioprinted skin model of cutaneous squamous cell carcinoma (cSCC) tumors together with a microscopy assay to test chemotherapeutic effects in tissue. (2020-07-07)
Multisample technique to analyze cell adhesion
An assay for imaging the physical interactions between multiple cell populations could help cancer research and treatment assessment. (2020-07-06)
Oncotarget: IQGAP1 control of centrosome function defines variants of breast cancer
The cover for issue 26 of Oncotarget features Figure 6, 'Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells,' by Osman, et al. and reported that IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown. (2020-06-30)
Racial disparities in surgery rates for esophageal cancer
Black patients with esophageal cancer are less likely to receive life-saving surgery for early-stage disease than white patients. (2020-06-25)
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