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Current Stem cell transplant News and Events, Stem cell transplant News Articles.
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Discovery in human acute myeloid leukemia could provide novel pathway to new treatments
Researchers at Mount Sinai have discovered that human acute myeloid leukemia (AML) stem cells are dependent on a transcription factor known as RUNX1, potentially providing a new therapeutic target to achieve lasting remissions or even cures for a disease in which medical advances have been limited. (2020-06-02)
Lab-grown miniature human livers successfully transplanted in rats
Using skin cells from human volunteers, researchers at the University of Pittsburgh School of Medicine have created fully functional mini livers, which they then transplanted into rats. (2020-06-02)
Study resolves controversy surrounding tumor suppressor gene's role in pluripotent ESCs
A new study released in STEM CELLS sorts through the maze of contradictions to finally determine that the multiple roles of p53 in cell cycle regulation and apoptosis are acquired during pluripotent stem cell differentiation. (2020-06-01)
When astrocytes attack: Stem cell model shows possible mechanism behind neurodegeneration
A new study published today in Neuron led by The New York Stem Cell Foundation (NYSCF) Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain -- from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers. (2020-06-01)
Summer forage capabilities of tepary bean and guar in the southern great plains
Research identifies tepary bean and guar as potential summer forages. (2020-05-28)
Combination therapy well-tolerated and highly effective for patients with IDH1-mutated AML
A combination therapy of ivosenidib (IVO) plus venetoclax (VEN) with or without azacitidine (AZA) was found to be effective against a specific genetic subtype of acute myeloid leukemia (AML) in a Phase Ib/II trial led by researchers at The University of Texas MD Anderson Cancer Center. (2020-05-28)
Stem cell treatments 'go deep' to regenerate sun-damaged skin
For a while now, some plastic surgeons have been using stem cells to treat aging, sun-damaged skin. (2020-05-28)
Scientists discover a gene to stay thin
An international team of researchers with the participation of IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences - reports the discovery of a thinness gene - ALK - conserved in evolution from flies to mice and importantly in very thin humans. (2020-05-28)
Carfilzomib does not improve outcomes in newly diagnosed myeloma compared to bortezomib
The combination of carfilzomib, lenalidomide, and dexamethasone (KRd) did not improve progression-free survival in patients with newly diagnosed myeloma absent a high-risk disease prognosis, compared with the standard of care -- bortezomib, lenalidomide, and dexamethasone (VRd). (2020-05-28)
Treatment shows promise in treating deadly brain cancer
In this study, researchers investigated if specific targeting of CD133+ glioblastoma with cutting-edge immunotherapy drugs could eradicate the most aggressive subpopulation of cells in the tumor. (2020-05-27)
Caveolin binding motif in Na/K-ATPase required for stem cell differentiation in animals
New findings reveal the importance of the Na/K-ATPase protein in stem cell differentiation and organogenesis, in a study led by scientists at Marshall University that involves the scaffolding function of the Na/K-ATPase. (2020-05-27)
June's SLAS Technology highlights papers authored by SLAS2019 Ignite award winner
The June issue of SLAS Technology features two related research papers authored by Georges Muller, Ph.D., (SEED Biosciences, Switzerland) the SLAS2019 Ignite Award winner and a top ten 2020 SLAS Innovation Award finalist. (2020-05-27)
Device simulates filtering and ion transport functions of human kidney
University of Arkansas researchers have developed a device that simulates the blood filtering and ion transport functions of the human kidney. (2020-05-27)
Researchers flag similarities between COVID-19 deaths and severe rheumatic illnesses
Rheumatologists at the University of Alberta are flagging similarities between the deaths of some COVID-19 patients and those with rheumatic illnesses, and are testing proven rheumatic treatments to see whether they help against the pandemic virus. (2020-05-27)
New method allows minimally invasive cell sampling
Northwestern Engineering researchers have developed one of the first non-destructive methods of extracting multiple samples from a cell over time. (2020-05-26)
Stem cells from placental amniotic membrane slow lung scarring in pulmonary fibrosis
In a study released today in STEM CELLS Translational Medicine (SCTM), researchers show for the first time how stem cells collected from human amniotic membrane can slow the progression of scarring in pulmonary fibrosis. (2020-05-26)
Rejuvenated fibroblasts can recover the ability to contract
A recent study from the Mechanobiology Institute at the National University of Singapore has shown that rejuvenated fibroblasts can recover their ability to self-contract. (2020-05-26)
Scientists find optimal age of stem cells
Biophysicists from MIPT and Vladimirsky Moscow Regional Clinical Research Institute have determined the optimal age of reprogrammed stem cells suitable for restoring heart tissue. (2020-05-26)
Unique insight into development of the human brain: Model of the early embryonic brain
Stem cell researchers from the University of Copenhagen have designed a model of an early embryonic brain. (2020-05-25)
Kidney transplantations: Better results with larger case volumes
Kidney transplantations: better results with larger case volumes. Survival probabilities increase in hospitals where kidneys are transplanted more frequently. (2020-05-25)
New method provides unique insight into the development of the human brain
Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. (2020-05-25)
Kidney transplants: Better results can be inferred from a larger number of cases
Kidney transplants: Better results can be derived with larger numbers of cases. (2020-05-22)
Combinatorial screening approach opens path to better-quality joint cartilage
High-throughput platform identifies complex conditions with biomaterial compositions, and mechanical and chemical stimuli that help stem cells produce more robust cartilage. (2020-05-22)
Cell-culture based test systems for anticancer drug screening
As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body. (2020-05-21)
New model shows how cells that cause liver cancer are created
Scientists have discovered how liver cancer spreads, but they haven't yet learned how liver cancer cells are born. (2020-05-21)
Iron nanorobots go undercover
Customizable magnetic iron nanowires pinpoint and track the movements of target cells. (2020-05-20)
At the crossroads
In the bone marrow, blood stem cells via precursor cells give rise to a variety of blood cell types with various functions: white blood cells, red blood cells, or blood platelets. (2020-05-20)
Image analysis technique provides better understanding of heart cell defects
Many patients with heart disease face limited treatment options. Fortunately, stem cell biology has enabled researchers to produce large numbers of cardiomyocytes, which may be used in drug screens and cell-based therapies. (2020-05-19)
Animal study shows human brain cells repair damage in multiple sclerosis
A new study shows that when specific human brain cells are transplanted into animal models of multiple sclerosis and other white matter diseases, the cells repair damage and restore function. (2020-05-19)
Texas A&M lab engineers 3D-functional bone tissues
Dr. Akhilesh K. Gaharwar, associate professor, has developed a highly printable bioink as a platform to generate anatomical-scale functional tissues. (2020-05-19)
Researchers find potential drug treatment targets for alcohol-related liver disease
A team of researchers from Massachusetts General Hospital has uncovered key molecular step stones in ALD that may provide targets for drug therapy development. (2020-05-19)
Clinical trial shows ability of stem cell-based topical solution to regrow hair
The results of a clinical trial released today in STEM CELLS Translational Medicine demonstrate how a topical solution made up of stem cells leads to the regrowth of hair for people with a common type of baldness. (2020-05-18)
Notorious cancer protein mutations cooperate to proliferate disease
Research at Kanazawa University, Theragen Etex Bio Institute and Seoul National University as reported in Nature Communications points towards pathways for the metastasis and malignant transitions that result from changes in the protein p53. (2020-05-18)
Smokers more likely to express ACE2 protein that SARS-COV-2 uses to enter human cells
Previous data from COVID-19 patients suggests that cigarette smokers are more likely to have health complications. (2020-05-18)
New research into stem cell mutations could improve regenerative medicine
Research from the University of Sheffield has given new insight into the cause of mutations in pluripotent stem cells and potential ways of stopping these mutations from occurring. (2020-05-14)
Critical window for re-infection with HIV after stem cell transplantation
So far, allogeneic stem cell transplantation for the treatment of severe blood cancers has been the only medical intervention to have cured at least three people infected with the HI virus. (2020-05-14)
Moffitt Cancer Center study suggests more could benefit from CAR T-cell therapy
Moffitt Cancer Center organized a consortium of 16 cancer treatment facilities across the US that offer Yescarta as a standard-of-care therapy for patients with relapsed/refractory large B cell lymphoma. (2020-05-14)
Study identifies group of genes with altered expression in autism
The dysregulation appeared to affect communication among neurons in the subjects of the study, which was conducted in Brazil. (2020-05-14)
Tracking an organism's development, cell by cell
Scientists have devised a mouse model that lets researchers track every cell in the body, from the embryonic stage until adulthood. (2020-05-14)
Cell therapy treatment for cardiac patients with microvascular dysfunction provides enhanced quality
Trial results presented today revealed a promising therapy for patients experiencing angina due to coronary microvascular dysfunction (CMD). (2020-05-14)
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