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Current Translational research News and Events

Current Translational research News and Events, Translational research News Articles.
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New DNA sequencing technique may help unravel genetic diversity of cancer tumors
Understanding the genetic diversity of individual cells within a cancer tumor and how that might impact the disease progression has remained a challenge, due to the current limitations of genomic sequencing. (2020-06-25)
Fighting the COVID-19 pandemic and major diseases at the same time
Researchers, politicians and funding bodies find themselves in front of a unique situation: The mounting pressure to accelerate and intensify efforts to tackle the COVID-19 pandemic while handling the growing threat from all other diseases endangering our society. (2020-05-14)
Dental care and oral health under the clouds of COVID-19
DR Clinical & Translational Research has published an invited commentary by researchers at the University of Rochester, Eastman Institute for Oral Health, NY, USA on dental care and the Coronavirus disease 2019 (COVID-19), including the provision of dental care and protecting patients and staff during the pandemic. (2020-04-28)
Study shows glaucoma could be successfully treated with gene therapy
A new study led by the University of Bristol has shown a common eye condition, glaucoma, could be successfully treated with a single injection using gene therapy, which would improve treatment options, effectiveness and quality of life for many patients. (2020-04-21)
Despite best intentions, researchers don't always share findings with study participants
Medical University of South Carolina investigators report in the Journal of Clinical and Translational Science that study participants want to know trial results but few have received this information. (2020-03-02)
Putting a finger on plant stress response
Researchers from the University of Tsukuba have found that a PHD zinc finger-like domain in SUMO E3 ligase SIZ1 is essential for protein function in Arabidopsis. (2020-02-05)
Activation of a distinct genetic pathway can slow the progress of metastatic breast cancer
Activation of the BMP4 signalling pathway presents a new therapeutic strategy to combat metastatic breast cancer, a disease that has shown no reduction in patient mortality over the past 20 years. (2020-01-16)
New twist in quest to develop understanding of time crystalline behavior
The quest to develop the understanding for time crystalline behaviour in quantum systems has taken a new, exciting twist. (2019-11-21)
Discovery of a bottleneck relief in photosynthesis may have a major impact on food crops
Scientists have found how to relieve a bottleneck in the process by which plants transform sunlight into food, which may lead to an increase in crop production. (2019-08-16)
Microbiome diversity builds a better mouse model
The path to building a better mouse model starts with the microorganisms that colonize it. (2019-08-01)
The declining impact of federal funding on cancer innovation
New research featured in Nature Biotechnology studies the impact of the funding by the National Institutes of Health in the field of cancer research. (2019-07-08)
Antidepressants can reduce the empathic empathy
Depression is a disorder that often comes along with strong impairments of social functioning. (2019-06-18)
Half-hearted: New insight into why the heart doesn't develop properly in some children
Investigators at the Medical University of South Carolina have found evidence that the gene Ccdc117 supports the rapid growth of precursor cells needed for proper development of right-sided heart structures. (2019-04-09)
Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients
Investigators at the Medical University of South Carolina report in Microbiome that autoantibody production in HIV-positive patients who have undergone antiretroviral therapy is linked to levels of Staphylococcus products in their blood. (2019-04-01)
Research identifies mechanism that helps plants fight bacterial infection
A team led by a plant pathologist at the University of California, Riverside, has identified a regulatory, genetic mechanism in plants that could help fight bacterial infection. (2019-02-28)
Researchers discover a genetic defect linked to pediatric liver disease
Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to biliary atresia (BA), the most common pediatric cause of end-stage liver disease, and the leading indication for liver transplantation in children. (2019-02-21)
Researchers identify a mechanism that fuels cancer cells' growth
The study, led by UCLA professors Claudio Scafoglio and David Shackelford, suggests that a biomarker can help scientists detect lung cancer earlier, when it is much easier to treat. (2018-11-14)
Stripping the linchpins from the life-making machine reaffirms its seminal evolution
This experiment had a good chance of crashing. Instead, it delivered whopping evidence to coroborrate the earliest evolution of the translational system, the mechanisms which make life out of our genes. (2018-11-09)
Does our environment affect the genes in our brains?
Is there a link between differences in IQ test performance and the activity of certain genes? (2018-09-24)
Smoking linked to higher dementia risk
In an Annals of Clinical and Translational Neurology analysis of nationwide health claims from Korea, men who smoked had an elevated risk of dementia. (2018-09-06)
New ESMO tumor DNA scale helps match patients with cancer to optimal targeted medicines
A new scale for tumour DNA mutations which will simplify and standardise choices for targeted cancer treatment has been agreed by leading cancer specialists in Europe and North America. (2018-08-20)
Aortic atherosclerotic plaque inflammation may contribute to the progression of fatty liver disease to liver fibrosis
A new study sheds light on the long-term effects of highly inflamed plaques on the progression of liver fibrosis. (2018-08-02)
Compound identified that protects against neurodegeneration
Researchers from the University of Liverpool have identified a new compound that protects against neurodegeneration in nematode worms. (2018-07-18)
Research points to potential shortcoming of antibiotic lab tests
To determine which antibiotics reliably treat which bacterial infections, diagnostic laboratories that focus on clinical microbiology test pathogens isolated from patients. (2018-07-06)
TGen-led study identifies gene expression patterns associated with fatty liver disease
In an effort towards discovering a drug target, scientists at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, for the first time have identified significant gene expression patterns associated with obesity-related NASH inflammation and fibrosis. (2018-06-22)
Hurricanes are slowing down, and that's bad news
Some hurricanes are moving more slowly, spending increased time over land and leading to catastrophic local rainfall and flooding, according to a new study published Wednesday (June 6) in the journal Nature. (2018-06-07)
Applied science may yield more translational research publications than basic science
While translational research can happen at any stage of the research process, a recent investigation of behavioral and social science research awards granted by the NIH between 2008 and 2014 revealed that applied science yielded a higher volume of translational research publications than basic science, according to a study published May 9, 2018 in the open-access journal PLOS ONE by Xueying Han from the Science and Technology Policy Institute, USA, and colleagues. (2018-05-09)
Researchers discover mitochondria-to-nucleus messenger protein
Researchers have identified a protein, G-Protein Pathway Suppressor 2 (GPS2), that moves from a cell's mitochondria to its nucleus in response to stress and during the differentiation of fat cells. (2018-03-01)
IDIBELL researchers successfully test a new combination therapy in sarcomas
Researchers of the Sarcoma group of the Oncobell program -- Bellvitge Biomedical Research Institute (IDIBELL) have successfully tested a new combined therapy for the treatment of this rare, aggressive tumor type, which affects children and adults. (2018-01-16)
Malaria parasite packs genetic material for trip from mosquitoes to humans
The parasite that causes malaria has not one, but two, specialized proteins that protect its genetic material until the parasite takes up residence in a new host. (2018-01-10)
Brain changes following childhood limb loss may be reversible
In a recent study, investigators found that certain changes in the brain that occurred after limb amputation in a child were reversible after restoring sensory input through bilateral hand transplantation. (2017-12-06)
One-size treatment for blood cancer probably doesn't fit all, USC researchers say
Though African-American men are three times more likely to be diagnosed with a blood cancer called multiple myeloma, most scientific research on the disease has been based on people of European descent. (2017-11-22)
New tool predicts risk of heart attack in older surgery patients
A tool designed to more accurately predict the risk of heart attack in older patients undergoing non-cardiac surgery works significantly better than traditional risk assessment tools. (2017-11-16)
Reducing the burden of neglected tropical diseases requires investments in basic research
International support for measures to prevent neglected tropical diseases has resulted in public health gains, but eliminating these debilitating conditions will require significant investments in basic research, argues Dr. (2017-11-09)
MS risk in children spotted with MRI brain scans
By the time multiple sclerosis (MS) is diagnosed in children, it may be difficult to prevent the disabilities and relapses that come with the disease. (2017-10-13)
Researchers help develop new antifungal drug
University researchers, working with F2G Limited (Eccles, Manchester), have developed a new antifungal drug to help in the treatment of life threatening invasive fungal infections such as invasive aspergillosis. (2017-10-06)
Playing American football before age 12 could have long-term health effects
Playing American football before the age of 12 may have long-term consequences for players' mood and behavior, according to a study involving 214 professional and amateur football players, published in the open access journal Translational Psychiatry. (2017-09-19)
Fetal membranes may help transform regenerative medicine
A new review looks at the potential of fetal membranes, which make up the amniotic sac surrounding the fetus during pregnancy, for regenerative medicine. (2017-08-30)
Drug safety for penguins
Researchers from the University of Liverpool have determined the most effective drug dose to help penguins in managed care fight off disease. (2017-08-04)
Psychopaths are better at learning to lie, say researchers
Individuals with high levels of psychopathic traits are better at learning to lie than individuals who show few psychopathic traits, according to a study published in the open access journal Translational Psychiatry. (2017-07-25)
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