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Current Transplantation News and Events

Current Transplantation News and Events, Transplantation News Articles.
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Loss of intestinal goblet cells causes fatal disease after stem cell transplantation
Allogeneic stem cell transplantation can cause a loss of protective goblet cells from the colon's inner lining, which can be fatal. (2020-07-01)
A revolutionary new treatment alternative to corneal transplantation
A new approach in ophthalmology that offers a revolutionary alternative to corneal transplantation has just been developed by researchers and clinicians in North America, Europe, and Oceania. (2020-06-30)
Researchers have found a promising therapy for cardiac regeneration
New research gives information in order to understand safety, efficacy and mechanisms of action of a new cardiac therapy. (2020-06-30)
Study finds HCV-positive livers safe for transplantation; Patients cured afterward
UC researchers find similar results for positive outcomes when comparing patients receiving livers infected with hepatitis C to patients who receive livers without infection. (2020-06-22)
A novel radioisotope therapy for children with neuroblastoma
Researchers from Kanazawa University retrospectively analyzed children with refractory or relapsed high-risk neuroblastoma who were treated with high-dose 131I-metaiodobenzylguanidine at Kanazawa University Hospital. (2020-06-19)
Liver perfusion could save 7 in 10 rejected donor livers
A major study investigating the effectiveness of liver perfusion as a technique to improve the function of donor livers that would have otherwise been rejected has shown that up to 7 in every 10 could be used after just 4-6 hours of the assessment. (2020-06-17)
For babies born with a rare immune deficiency, a unique new test to better target care
A new test developed at CHU Sainte-Justine in Montreal will enable better management of patients with severe combined immunodeficiency (SCID). (2020-06-17)
Fred Hutch and University of Washington experts: Treat COVID-19 earlier to save lives
Infectious disease experts from Fred Hutchinson Cancer Research Center and UW Medicine are advocating for earlier actions to reduce hospitalizations and deaths from COVID-19. (2020-06-16)
Women are not more likely to die of cirrhosis than men, despite fewer liver transplants
Prior studies suggested women might have higher mortality of cirrhosis of the liver than men. (2020-06-04)
Kidney transplantations: Better results with larger case volumes
Kidney transplantations: better results with larger case volumes. Survival probabilities increase in hospitals where kidneys are transplanted more frequently. (2020-05-25)
Kidney transplants: Better results can be inferred from a larger number of cases
Kidney transplants: Better results can be derived with larger numbers of cases. (2020-05-22)
Critical window for re-infection with HIV after stem cell transplantation
So far, allogeneic stem cell transplantation for the treatment of severe blood cancers has been the only medical intervention to have cured at least three people infected with the HI virus. (2020-05-14)
Immune system discovery paves way to lengthen organ transplant survival
A new discovery in mice shows the innate immune system has 'memory,' previously thought to be a unique feature of the adaptive immune system. (2020-05-08)
Researchers have found accumulation of gene mutations in chronic Graft-versus-host disease
Mutations in white blood cells can contribute to abnormal immune profile after hematopoietic stem cell transplantation. (2020-05-07)
UB investigators uncover cellular mechanism involved in Krabbe disease
Researchers determined which cells are involved in Krabbe disease and by which mechanism. (2020-05-05)
Research suggests new therapeutic target for kidney diseases
Researchers have published a new study that suggests a signaling pathway called ROBO2 is a therapeutic target for kidney diseases, specifically kidney podocyte injury and glomerular diseases. (2020-05-04)
Landmark 30-year study on Crigler-Najjar syndrome underscores the need for new therapies
A new study summarizes more than 30 years of clinical experience and describes the clinical course of 28 individuals homozygous for damaging mutations in the UGT1A1 gene who were born between 1984 and 2015 with Crigler-Najjar syndrome. (2020-04-16)
Researchers restore sight in mice by turning skin cells into light-sensing eye cells
Researchers have discovered a technique for directly reprogramming skin cells into light-sensing rod photoreceptors used for vision, sidestepping the need for stem cells. (2020-04-15)
Researchers successfully repair stroke-damaged rat brains
Researchers at Lund University in Sweden have succeeded in restoring mobility and sensation of touch in stroke-afflicted rats by reprogramming human skin cells to become nerve cells, which were then transplanted into the rats' brains. (2020-04-08)
New 'more effective' stem cell transplant method could aid blood cancer patients
Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults. (2020-03-26)
For clogged and hardened hearts, a mussel is the solution
Prof. Hyung Joon Cha and his research team developed a stem cell therapy on myocardial infarction, using proteins that can be found in mussels, mussel adhesive proteins. (2020-03-25)
Distance to transplant center and likelihood of being considered for transplantation
In an analysis of information on adults who began treatment for kidney failure at any Georgia, North Carolina, or South Carolina dialysis facility, the distance from a patient's residence to the nearest transplant center did not appear to affect the likelihood of transplant-related referrals and evaluations. (2020-03-24)
UCI team demonstrates ability to supercharge cells with mitochondrial transplantation
UCI researchers have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. (2020-03-23)
Early blood marker may predict future risk of kidney transplant failure
In a study of kidney transplant recipients, the composition of certain immune cells in the blood 1 year after kidney transplantation was linked with a patient's subsequent risk of kidney transplant failure. (2020-03-12)
PET imaging offers new insights into post-transplant care for heart patients
Myocardial blood flow (MBF) and myocardial flow reserve (MFR) have been identified as accurate indicators for graft failure after cardiac transplantation, according to research published in The Journal of Nuclear Medicine. (2020-03-05)
Study reveals improving survival rates after liver transplantation in the UK
In the past two decades, death rates after liver transplantation have dropped by more than half in the UK, according to a recent analysis of almost 10,000 liver transplant recipients published in BJS (British Journal of Surgery). (2020-03-04)
Mount Sinai researchers discover new approach for use of stem cells to improve bone marrow transplantation
Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation, according to a study published on Feb. (2020-02-27)
Elderly patients also benefit from kidney transplantation
So far, kidney transplantation has generally not been offered to elderly patients (>75 years) because of the perioperative risks. (2020-02-26)
New tool aids patients in selecting a transplant center
A new website developed by researchers at Hennepin Healthcare Research Institute (HHRI) and the University of Minnesota (UMN) is making it easier for organ transplant candidates to choose which transplant center is right for them. (2020-02-24)
First Swedish transplant of uterus from deceased donor
The Swedish team responsible for uterine transplantation research has, for the first time, transplanted a uterus from a deceased donor. (2020-02-17)
Kidney patients benefit using organs from Hepatitis C-infected donors
Kidney patients benefit by accepting kidneys from donors with hepatitis C, according to a University of Cincinnati physician-researcher. (2020-02-17)
UC research could help reduce disease incidence in organ donors
Researchers at the University of Cincinnati are among the first to adopt genotyping that helps identify and predict the risk accompanying individuals wishing to donate a kidney. (2020-02-11)
City of Hope's Triplex vaccine reduces rate of CMV complications in transplant recipients
Patients who underwent a stem cell transplant and received the Triplex vaccine to prevent a type of herpes virus -- cytomegalovirus (CMV) -- from duplicating out of control were 50% less likely to develop health complications related to the virus than patients who did not take Triplex, according to a City of Hope-led study published today in Annals of Internal Medicine. (2020-02-10)
The economic burden of kidney transplant failure in the United States
A recent analysis published in the American Journal of Transplantation estimates that for the average US patient who has undergone kidney transplantation, failure of the transplanted organ (graft failure) will impose additional medical costs of $78,079 and a loss of 1.66 quality-adjusted life years. (2020-02-05)
Virtual crossmatching improves quality of life for kidney transplant patients
Virtual antibody crossmatching is a safe and efficient way of selecting kidney transplant recipients. (2020-01-31)
30-year study identifies need of disease-modifying therapies for maple syrup urine disease
A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders. (2020-01-24)
Subtle structural features in donated kidneys may predict risk of transplant failure
Mayo Clinic researchers have discovered that subtle structural features in kidneys from living donors that can only be seen with a microscope may predict the risk of transplant failure in recipients. (2020-01-23)
Certain liver cells may help prevent organ rejection after transplant, study finds
Mesenchymal stromal cells from fat tissue and bone marrow are widely used in therapeutic trials for their anti-inflammatory qualities, but new Mayo Clinic research finds that liver cells may be of greater value. (2020-01-21)
Machine keeps human livers alive for one week outside of the body
Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keeps them alive outside the body for one week. (2020-01-13)
New research may lead to increased use of available hearts for transplant
A new study provides hope that the number of children dying on the transplantation list while waiting for a new heart could potentially be reduced dramatically. (2020-01-06)
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