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Current Tumor cells News and Events

Current Tumor cells News and Events, Tumor cells News Articles.
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Molecular target UNC45A is essential for cancer but not normal cell proliferation
Identifying a protein that plays a key role in cancer cell growth is a first step toward the development of a targeted cancer therapy. (2019-04-19)
IDIBELL -- ICO researchers set new bases to develop therapies against colorectal cancer
IDIBELL -- ICO researchers in Barcelona have found that inactivation of two proteins make tumoral cells more sensitive to chemotherapy. (2019-04-17)
Diet high in leucine may fuel breast cancer's drug resistance
A team led by Senthil Muthuswamy, PhD, at the Cancer Center at Beth Israel Deaconess Medical Center, has discovered an unexpected relationship between levels of the amino acid leucine (found in beef, chicken, pork and fish and other foods) and the development of tamoxifen resistance in ER+ breast cancer. (2019-04-17)
Key protein a possible new target in the treatment of pancreatic cancer
Pancreatic Cancer Collective-funded research (Lustgarten Foundation and Stand Up To Cancer) from Dr. (2019-04-17)
New study targets Achilles' heel of pancreatic cancer, with promising results
Advanced pancreatic cancer is often symptomless, leading to late diagnosis only after metastases have spread throughout the body. (2019-04-17)
Researchers pinpoint tumor-related protein, slow progression of cancers
A new study in Nature has identified a potential strategy for treating multiple forms of cancerous tumors: targeting a protein that maliciously rewires immune cells and impedes cancer therapies. (2019-04-17)
Triple negative breast cancers can adopt reversible state that is resistant to chemotherapy
Researchers at The University of Texas MD Anderson Cancer Center have discovered that triple negative breast cancer (TNBC) cells can develop resistance to frontline, or neoadjuvant, chemotherapy not by acquiring permanent adaptations, but rather transiently turning on molecular pathways that protect the cells. (2019-04-17)
New study explains how inflammation causes gastric cancer
Researchers from Kanazawa University and the Japan Agency for Medical Research and Development have solved the decades-old mystery of how stomach bacterium Helicobacter pylori causes gastric cancer. (2019-04-16)
New role for innate immune sensor: Suppressing liver cancer
UT Southwestern researchers have found that a protein in the body's innate immune system that responds to gut microbes can suppress the most common type of liver cancer. (2019-04-16)
The fluid that feeds tumor cells
MIT biologists have found that the nutrient composition of the interstitial fluid that normally surrounds pancreatic tumors is different from that of the culture medium normally used to grow cancer cells. (2019-04-16)
Three studies show how tumors hijack the immune system to resist radiation therapy
Treg cells turn off the immune system. Three recent studies show that targeting tregs may increase the effectiveness of anti-cancer immunotherapies. (2019-04-16)
Rare but important gene target found in many tumor types, suggesting new therapy possible
A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion they believe is responsible for development of a wide spectrum of cancer types. (2019-04-15)
Moffitt researchers identify mechanism of resistance to BRAF inhibitors in melanoma
Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. (2019-04-15)
Decoding cancer's molecular signature
New algorithm successfully identifies patients with a tumor-fueling DNA repair defect found in multiple cancers and treatable with a common cancer drug. (2019-04-15)
Princeton scientists discover an interaction that helps cancers spread to bone
A Princeton-led team of researchers have discovered a factor that promotes the spread of cancers to bone, opening the way toward treatments that could mitigate cancer's ability to colonize bone. (2019-04-15)
Precise decoding of breast cancer cells creates new option for treatment
Researchers at the University of Zurich and from IBM Research have investigated the vary-ing composition of cancer and immune cells in over one hundred breast tumors. (2019-04-15)
Bright spot analysis for photodynamic diagnosis of brain tumors using confocal microscopy
A Japan-based research team led by Kanazawa University have found that bright spot areas have generally lower fluorescence in brain tumors than in normal tissues in images captured by irradiation with a 405 nm wavelength laser and 544.5-619.5 nm band-pass filter. (2019-04-11)
Shutting down deadly pediatric brain cancer at its earliest moments
Cell-by-cell genetic analyses of developing brain tissues in neonatal mice and laboratory models of brain cancer allowed scientists to discover a molecular driver of the highly aggressive, deadly, and treatment-resistant brain cancer, glioblastoma. (2019-04-11)
'Nanobodies' from alpacas could help bring CAR T-cell therapy to solid tumors
Most CAR T-cell therapies look for antigens specific to cancer cells. (2019-04-11)
Cancer: Central role of cell 'skeleton' discovered
All cells possess a cytoskeleton which allows them to move and maintain their shape. (2019-04-10)
Loss of a DNA repair system creates a unique vulnerability in many cancer types
Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. (2019-04-10)
Single-cell sequencing reveals landscape of immune cell subtypes in lung cancer tumors
Single-cell sequencing reveals 25 subpopulations of myeloid cells, a poorly understood family of immune cells, in lung cancer tumors. (2019-04-09)
Immune cells fighting blood cancer visualized for the first time
When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease. (2019-04-08)
Scientists compared ways of drug delivery to malignant tumors
A team of biologists from Sechenov First Moscow State Medical University and Lobachevsky University (Nizhny Novgorod) analyzed available methods of targeted drug delivery to malignant tumors. (2019-04-08)
Mount Sinai researchers develop treatment that turns tumors into cancer vaccine factories
Researchers at Mount Sinai have developed a novel approach to cancer immunotherapy, injecting immune stimulants directly into a tumor to teach the immune system to destroy it and other tumor cells throughout the body. (2019-04-08)
Quashing the resistance: MicroRNA regulates drug tolerance in subset of lung cancers
Relapse of disease following conventional treatments remains one of the central problems in cancer management, yet few therapeutic agents targeting drug resistance and tolerance exist. (2019-04-08)
Breakthrough in knowledge of how some sarcomas arise
The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. (2019-04-08)
Spying on cells eating habits could aid cancer diagnosis
Scientists at the University of Edinburgh have developed a new imaging technology to visualize what cells eat, which could aid the diagnosis and treatment of diseases such as cancer. (2019-04-07)
Black nanoparticles slow the growth of tumors
The dark skin pigment melanin protects us from the sun's damaging rays by absorbing light energy and converting it to heat. (2019-04-04)
Genome-wide analysis reveals new strategies to target pancreatic cancer
An international team of scientists led by researchers at University of California San Diego School of Medicine employed an array of next-generation sequencing and gene-editing tools, such as CRISPR, to map the molecular dependencies - and thus vulnerabilities -- of pancreatic cancer stem cells. (2019-04-04)
Cancer exports molecular 'saboteurs' to remotely disarm immune system
Immunotherapy drugs known as checkpoint inhibitors have revolutionized cancer treatment: many patients with malignancies that until recently would have been considered untreatable are experiencing long-term remissions. (2019-04-04)
Researchers determine how a major tumor suppressor pathway becomes deactivated
The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans. (2019-04-04)
Moffitt Cancer Center researchers identify one way T cell function may fail in cancer
Moffitt Cancer Center researchers have discovered a mechanism by which one type of immune cell, CD8+ T cells, can become dysfunctional, impeding its ability to seek and kill cancer cells. (2019-04-04)
Parkinson's clues seen in tiny fish could aid quest for treatments
Parkinson's patients could be helped by fresh insights gained from studies of tiny tropical fish. (2019-04-04)
Gene levels could help predict prognosis for colorectal cancer
Levels of a gene that helps the immune system differentiate the good cells from the bad could be a good indicator of prognosis in people with colorectal cancers, Medical College of Georgia researchers report. (2019-04-03)
Researchers discover why men are more likely to develop liver cancer
Researchers in Spain have discovered that a hormone secreted by fat cells that is present at higher levels in women can stop liver cells from becoming cancerous. (2019-04-03)
New formula better predicts speed of tumor growth in 12 cancers
University at Buffalo researchers have developed a new method to more accurately predict tumor growth rates, a crucial statistic used to schedule screenings and set dosing regimens in cancer treatment. (2019-04-03)
Mayo Clinic finds 3 factors extend life for advanced pancreatic cancer patients
Historically, most pancreatic cancer patients whose tumors grow outside the pancreas to encompass veins and arteries have been told the cancer is inoperable and they should prepare for an average survival time of 12 to 18 months. (2019-04-02)
Breakthrough alpha-ray treatment of cancer without external radiation
Radioactive iodine has been used for treatment of thyroid cancer. (2019-04-02)
Combo of virotherapy and radiotherapy shows early promise in patients with esophageal cancer
The experimental oncolytic adenovirus telomelysin (OBP-301) in combination with radiotherapy was safe and showed early clinical efficacy in vulnerable patients with esophageal cancer, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3. (2019-04-02)
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