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Current Tumor cells News and Events

Current Tumor cells News and Events, Tumor cells News Articles.
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'Trojan horse' anticancer drug disguises itself as fat
A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors. (2019-07-18)
Discovery shows how difficult-to-treat prostate cancer evades immune system
Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the the immune system. (2019-07-18)
Researchers confirm the validity of xenographic models for studies of methylation
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify methylation patterns associated with different subtypes of breast cancer, and a subclassification of the group of ''triple negatives'', a breast cancer type typically associated with poor prognosis. (2019-07-18)
A study demonstrates that p38 protein regulates the formation of new blood vessels
Ángel R. Nebreda's team (IRB Barcelona) publishes a study in the journal Nature Communications addressing the role of the p38 protein in angiogenesis--the formation of new blood vessels--a critical process that fuels tumour cells and allows them to grow and eventually develop metastases. (2019-07-17)
Crunching the numbers of cancer metastasis
While revealing that metastatic breast cancer cells alter their shape to spread to other regions of the body, researchers develop a mathematical model that can be applied to study similar cellular systems. (2019-07-17)
Making cancer stem cells visible to the immune system
Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. (2019-07-17)
The protein that gives identical cells individuality
New insight into a protein's role in regulating tight DNA packing could have implications for combating tumor cell resistance to anti-cancer treatments. (2019-07-16)
Cancer device created at rutgers to see if targeted chemotherapy is working
Rutgers researchers have created a device that can determine whether targeted chemotherapy drugs are working on individual cancer patients. (2019-07-16)
Tightening the tumor-targeting abilities of checkpoint blockade immunotherapy
Seeking to improve upon existing checkpoint inhibitor therapies, scientists have developed a common checkpoint inhibitor (anti-PD-L1) in a nanoparticle formulation, which were activated specifically at tumor sites in mouse models of cancer. (2019-07-12)
Elegant antibody nanoparticles override immunological tolerance of tumors
Scientists from the Shanghai Institute of Materia Medica (SIMM) of the Chinese Academy of Sciences have developed a tumor enzymatic microenvironment-activatable antibody nanoparticle for robust cancer immunotherapy. (2019-07-12)
How DNA outside cells can be targeted to prevent the spread of cancer
Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. (2019-07-11)
Successful T cell engineering with gene scissors
The idea of genetically modifying a patient's own immune cells and deploying them against infections and tumors has been around since the 1980s. (2019-07-11)
Enzyme responsible for dangerous properties of brain tumor stem cells
The relapse of brain tumors after therapy is driven by cancer stem cells that were not affected by the treatment. (2019-07-11)
UC San Diego cancer scientists identify new drug target for multiple tumor types
A dysfunctional enzyme involved in building cancer cell membranes helps fuel tumor growth; when it's disabled or depleted in mouse models, tumors shrank significantly. (2019-07-11)
New vaccine strategy boosts T-cell therapy
Super-charging a treatment for leukemia also makes it effective on solid tumors. (2019-07-11)
Elicio Therapeutics' Darrell Irvine co-authors research published in Science
Elicio Therapeutics, a next generation immuno-oncology company, today announced that studies of its Amphiphile platform in combination with CAR-T therapy (AMP-CAR-T) have shown that activation of CAR-T cells in the lymphatic system gives massive CAR-T cell expansion, and significant functional improvements including enhanced CAR-T cell infiltration of solid tumors, increased anti-tumor cytolytic potential, and improved cytokine response. (2019-07-11)
New alternate cell growth pathway could lead to better treatments for metastatic cancers
A UCLA Dentistry led research study has found that the gene, mEAK-7, which they discovered last year, may play a key role in cancer metastasis. (2019-07-11)
A human liver cell atlas
The cellular composition of the liver is incompletely understood. Researchers at the Max Planck Institute for Immunobiology and Epigenetics have created a comprehensive map of all cell types in the healthy human liver using a method named single-cell RNA sequencing. (2019-07-10)
Therapeutic strategies based on evolutionary principles may improve patient outcomes
In a new article published by Cancer Research, Moffitt Cancer Center researchers propose the evolutionary dynamics of background extinctions suggest this focus on finding new and better drugs may have neglected opportunities to develop new and better treatment strategies to improve outcomes with currently available drugs. (2019-07-09)
Cancer genes and the tumor milieu
In a recent study published in Cancer Research, researchers demonstrate the role of an oncogene in altering the immediate environment of tumors. (2019-07-08)
Killing the seeds of cancer: A new finding shows potential in destroying cancer stem cells
When doctors remove a tumor surgically or use targeted therapies, the cancer may appear to be gone. (2019-07-08)
Natural antioxidant helps improve immune-based therapies by modulating T-cells
Researchers at the Medical University of South Carolina discovered a way to improve immune-based treatments by modulating T-cells. (2019-07-08)
Blood test may predict risk of recurrence for breast cancer patients
A special blood test may one day predict if a newly diagnosed breast cancer patient will likely relapse years later. (2019-07-08)
Treatment target pinpointed for liver cancer in teens and young adults
New findings show how a genetically aberrant, fused protein molecule, created by a liver cell mutation, promotes a rare, difficult to treat, cancer in young people. (2019-07-08)
Imprinted spheres fight breast cancer
A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles ''imprinted'' with specific binding sites for the receptor molecule HER2. (2019-07-03)
Bacteria engineered as Trojan horse for cancer immunotherapy
Researchers at Columbia Engineering and Columbia University Irving Medical Center announced today that they have engineered a strain of non-pathogenic bacteria that can colonize solid tumors in mice and safely deliver potent immunotherapies, acting as a Trojan Horse that treats tumors from within. (2019-07-03)
Immune-boosting compound makes immunotherapy effective against pancreatic cancer
Researchers at Washington University School of Medicine in St. Louis and Rush University in Chicago have found a compound that promotes a vigorous immune assault on pancreatic cancer. (2019-07-03)
Reprogramming pancreatic cancer
A type of white blood cell that has been especially susceptible to being deceived by pancreatic cancer cells into not attacking them can be 're-programmed' via a specially designed molecule that activates a protein found on their surfaces. (2019-07-03)
Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence
Researchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors - known as pNETs - that have dramatically different risks of recurrence following surgical treatment [or surgery]. (2019-07-03)
Researchers at IDIBELL-ICO describe a new resistance mechanism
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) and the ProCure Program of the Catalan Institute of Oncology (ICO) published today at Cancer Research a study describing a new mechanism in cancer that turns cells into malignant cells and contradicts what had been published so far about drug resistance that prevent the formation of blood vessels (anti-angiogenics). (2019-07-02)
FEFU scientists teamed up with colleagues to develop ointment for skin cancer prevention
Scientists from Far Eastern Federal University (FEFU), V.I. Vernadsky Crimean Federal University, Dmitry Mendeleev University of Chemical Technology, and Far Eastern Branch of the Russian Academy of Sciences (FEB RAS), assumed the risks of primary skin cancer and its recurrences can be significantly reduced by applying the ointment with antisense oligonucleotides which are short DNA, RNA fragments used in oncology to suppress the synthesis of tumor proteins. (2019-07-02)
High doses of 60 plus-year-old chemo drug found to spur immune system attack on lymphoma
Cyclophosphamide, a mainstay of chemotherapy for many cancers, acts as both chemotherapy and immunotherapy at high doses, study finds. (2019-07-01)
Researchers identify new way to make cancer self-destruct
Researchers have identified a method that can make tumors grow too quickly and die from the stress. (2019-07-01)
Cancer cell's 'self eating' tactic may be its weakness
Researchers reveal how pancreatic cancer cells adapt to the low energy environment of a tumor: by eating their own mitochondria! (2019-07-01)
NETRF-funded research may help predict pancreatic neuroendocrine tumor (pNET) recurrence
NETRF-funded researchers identified a cancer cell type that is associated with non-functional pancreatic neuroendocrine tumor (pNET) recurrence. (2019-07-01)
Breakthrough in how cells link together has implications in the proliferation of cancer
The discovery, which builds on Dr. Rafael Garcia-Mata's research focus of how cancer cells spread throughout the body, is intriguing because it explains the behavior of cells that are by far the most common starting place for cancer. (2019-06-27)
Helping select the cells with the most potential
Little is known about the mechanisms by which mammalian cells grow and differentiate during the handful of days between fertilization of the egg and implantation of the blastocyst in the uterus. (2019-06-27)
Nutritional cues regulate pancreatic tumor's 'cell drinking'
Desperate for nutrients, rapidly growing pancreatic tumors resort to scavenging 'fuel' through an alternative supply route, called macropinocytosis. (2019-06-27)
Pathway discovered that prevents buildup of Alzheimer's protein
St. Jude Children's Research Hospital scientists have discovered a pathway that functions like a car wash to prevent the buildup of a toxic protein associated with Alzheimer's disease. (2019-06-27)
Uridine diphosphate glucose found to dampen lung cancer metastasis
In a study published online in Nature on June 26, research teams led by Dr. (2019-06-26)
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