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Current Tumor cells News and Events, Tumor cells News Articles.
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Paper-based technology advances earlier cancer detection
Washington State University researchers have developed a technology that is more than 30 times more sensitive than current lab-based tests in finding early stage cancer biomarkers in blood. (2020-06-04)
New role assigned to a human protein in transcription and genome stability
DNA-RNA hybrids, or R loops, are structures that generate genomic instability, a common feature of tumor cells. (2020-06-04)
International study approaches new therapeutic strategies for lung cancer
The international study ''Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures'', recently published in the scientific journal Nature Communication, has taken a further step in the development of new therapeutic strategies to treat lung cancer. (2020-06-04)
Advances in nanoparticles as anticancer drug delivery vector: Need of this century
This review article provides a summary of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. (2020-06-04)
Unique cells found in lung cancer patients may predict survival
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer where tumor cells shed from the main tumor circulate in the blood and settle in other organs and metastasize. (2020-06-03)
'Terminator' protein halts cancer-causing cellular processes
New research from the lab of Hening Lin, professor of chemistry and chemical biology in the College of Arts and Sciences, finds that a protein called TiPARP acts as a terminator for several cancer-causing transcription factors, including HIF-1, which is implicated in many cancers, including breast cancer. (2020-06-03)
Tumors disrupt the immune system throughout the body
Cancer treatment has advanced with the advent of immunotherapies that, in some cancers, can overcome tumors' ability to evade the immune system by suppressing local immune responses. (2020-06-03)
Tulane scientists find a switch to flip and turn off breast cancer growth and metastasis
Researchers at Tulane University School of Medicine identified a gene that causes an aggressive form of breast cancer to rapidly grow. (2020-06-02)
New CRISPR advance may solve key quandary
A mutation unique to certain cancer tumors is a potential homing beacon for safely deploying CRISPR gene editing enzymes to disarm DNA that makes cancer cells resistant to treatment, while ignoring the gene in normal cells where it's critical to healthy function, according to to a new study from ChristianaCare's Gene Editing Institute in the journal Molecular Cancer Research. (2020-06-02)
Publication in Nature Communications highlights the preclinical development of SYNB1891
Synlogic today announced the publication in Nature Communications of preclinical data supporting its first clinical immuno-oncology program, SYNB1891, which is being evaluated in a Phase 1 clinical trial in patients with advanced solid tumors or lymphoma. (2020-06-01)
Resistance to immunosurveillance favors cluster cancer metastasis
Researchers at Baylor College of Medicine show that circulating cancer cell clusters are more resistant to NK-cell mediated destruction than single cancer cells, leading to more cluster metastasis. (2020-06-01)
A boost for cancer immunotherapy
MIT engineers have found a way to boost the effectiveness of cancer immunotherapy drugs called checkpoint inhibitors. (2020-06-01)
Researchers identify key immune checkpoint protein that operates within T cells
A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. (2020-06-01)
Researchers identify a moving target in small cell lung tumors
About 15% of lung cancers are classified as small cell lung cancer. (2020-06-01)
Targeted therapy pralsetinib achieves high response rates in advanced cancers with RET gene fusions
The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW trial, led by researchers at The University of Texas MD Anderson Cancer Center. (2020-05-29)
Adoptive T-cell therapy ADP-A2M4 targeting MAGE-A4 shows early activity in patients with advanced solid tumors
The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center. (2020-05-29)
Exploiting viruses to attack cancer cells
Hokkaido University scientists have made an adenovirus that specifically replicates inside and kills cancer cells by employing special RNA-stabilizing elements. (2020-05-28)
Mapping immune cells in brain tumors
It is not always possible to completely remove malignant brain tumors by surgery so that further treatment is necessary. (2020-05-28)
WPI-led research team shrinks breast cancer tumors in mice with targeted therapy
A team of researchers led by Worcester Polytechnic Institute Provost Wole Soboyejo attached anti-cancer agents to the hormone LHRH to create drugs that targeted triple-negative breast cancer, which typically does not respond to conventional targeted cancer therapies. (2020-05-28)
Colorado tool, My-DST, may pick best multiple myeloma treatment
Response of liquid biopsies to approved drugs can help show resistance, predict response. (2020-05-28)
Novel targeted drug induced positive response for VHL-associated kidney cancer
In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)-associated renal cell carcinoma (RCC). (2020-05-28)
Ludwig Lausanne study charts the immune landscape of multiple brain cancers
A Ludwig Cancer Research study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast and skin. (2020-05-28)
A comprehensive survey reveals bacteria are widespread in human tumors and differ by tumor type
Different human tumor types each harbor their own unique bacterial communities, researchers report in a new study that profiled the microbiomes of more than 1,500 individual tumors across seven types of human cancer - the most comprehensive tumor microbiome study to date. (2020-05-28)
Blocking tumor signals can hinder cancer's spread
A University of Pennsylvania-led team used an inhibitor of an enzyme called p38α kinase to suppress the spread of melanoma to the lungs in a mouse model. (2020-05-28)
Surgery and radiation do not extend survival in newly diagnosed metastatic breast cancer
Women who present with a new diagnosis of breast cancer that is already in an advanced stage (stage IV) face questions about having surgery and radiation to the tumor in the breast (local therapy). (2020-05-28)
Pregnancy reprograms breast cells, reducing cancer risk
Women who are pregnant before the age of 25 have a decreased risk of breast cancer throughout their lives. (2020-05-27)
New cancer immunotherapy targeting myeloid cells slows tumor growth
Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of Pennsylvania and other institutions. (2020-05-27)
New method allows minimally invasive cell sampling
Northwestern Engineering researchers have developed one of the first non-destructive methods of extracting multiple samples from a cell over time. (2020-05-26)
High-resolution 3D view inside tumors
Breast cancer is the most common cancer in women. But individual tumors can vary significantly, presenting different spatial patterns within their mass. (2020-05-26)
Lymph node metastases form through a wider evolutionary bottleneck than distant metastases
A Mass General-led research team has shown that lymph node and distant metastases develop through different evolutionary mechanisms. (2020-05-26)
Anti-malarial drug shows promise for brain cancer treatment
Glioblastoma multiforme (GBM) is an aggressive form of cancer in the brain that is typically fatal. (2020-05-26)
New double-contrast technique picks up small tumors on MRI
Early detection of tumors is extremely important in treating cancer. (2020-05-25)
Study reveals first evidence inherited genetics can drive cancer's spread
Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. (2020-05-25)
New therapy for triple negative breast cancer
Researchers at the Principe Felipe Research Center (CIPF), the Universitat Politècnica de València (UPV), CIBER-BBN and the Institute for Research in Biomedicine (IRB) of Barcelona have inhibited tumor growth and reduced metastasis, as well as the toxicity of the antitumor drug Navitoclax in preclinical animal models of triple negative breast cancer (TNBC). (2020-05-25)
Researchers develop high-performance cancer vaccine using novel microcapsules
Scientists from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have developed a new therapeutic tumor vaccine based on self-healing polylactic acid microcapsules, which can efficiently activate the immune system and inhibit tumor development. (2020-05-22)
Cancer researchers gain valuable insights through a comprehensive review of Clioquinol
Researchers at Karmanos Cancer Institute of Wayne State University compiled the latest cancer research on clioquinol (CQ), an anti-fungal/anti-protozoal hydroxyquinoline family drug. (2020-05-21)
Cell-culture based test systems for anticancer drug screening
As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body. (2020-05-21)
New model shows how cells that cause liver cancer are created
Scientists have discovered how liver cancer spreads, but they haven't yet learned how liver cancer cells are born. (2020-05-21)
Nanobowls serve up chemotherapy drugs to cancer cells
For decades, scientists have explored the use of liposomes -- hollow spheres made of lipid bilayers -- to deliver chemotherapy drugs to tumor cells. (2020-05-20)
New liver cancer research targets non-cancer cells to blunt tumor growth
'Senotherapy,' a treatment that uses small molecule drugs to target ''senescent'' cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, PhD, a professor of Cell and Developmental Biology in the Perelman School of Medicine at the University of Pennsylvania and scientific director of the Abramson Family Cancer Research Institute. (2020-05-20)
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