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Current Tumor cells News and Events

Current Tumor cells News and Events, Tumor cells News Articles.
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A compound effective to chemotherapy-resistant cancer cells identified
A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity. (2019-10-18)
Creatine powers T cells' fight against cancer
The study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of killer T cells, the foot soldiers of the immune system. (2019-10-18)
New marker for tumor aggression in neurofibromatosis type 1
Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1. (2019-10-16)
Cause of drug resistance in a drug resistance in intestinal tumors identified
Researchers clarify mechanisms that allow hard-to-treat cancers to develop, and have identified strategies that could lead to new therapies. (2019-10-16)
Pioneering cell therapies for non-responders to current immunotherapies
Research led by VHIO's Alena Gros signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low mutational burden who are refractory to approved immune-based treatments. (2019-10-16)
Drug-light combo could offer control over CAR T-cell therapy
UC San Diego bioengineers are a step closer to making CAR T-cell therapy safer, more precise and easy to control. (2019-10-15)
Glowing particles in the blood may help diagnose and monitor brain cancer
A chemical that has improved surgeries for brain cancer by making tumor cells fluorescent may also help doctors safely diagnose the disease and monitor its response to treatment. (2019-10-15)
Yale scientists help immune system find hidden cancer cells
Cancer cells are masters at avoiding detection, but a new system developed by Yale scientists can make them stand out from the crowd and help the immune system spot and eliminate tumors that other forms of immunotherapies might miss, researchers report Oct. (2019-10-14)
Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A
Cyclooxygenase-2 is overexpressed in bladder cancer cells, making it an attractive molecular target for the detection and treatment of cancer. (2019-10-14)
A Yale-developed drug shows promise as immune therapy for cancers
A therapy developed by Yale researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. (2019-10-14)
Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial
RESILIENT was a single arm, open label, phase II/III study to test if label agnostic therapy regimens guided by Encyclopedic Tumor Analysis can offer meaningful clinical benefit for patients with relapsed refractory metastatic malignancies. (2019-10-11)
Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment
The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models. (2019-10-11)
Gut immunity more developed before birth than previously thought
The first comprehensive look at the immune system of the fetal gut shows that it is far more developed before birth, and could help develop new maternal vaccines and reveal if we are predisposed to autoimmune diseases before birth. (2019-10-10)
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity
The researchers have recently identified the tumor suppressor tuberous sclerosis complex 1 as a new co-chaperone of Hsp90 that affects Hsp90 binding to its inhibitors. (2019-10-10)
Algorithm personalizes which cancer mutations are best targets for immunotherapy
As tumor cells multiply, they often spawn tens of thousands of genetic mutations. (2019-10-09)
Bioelectricity's promise for therapeutic targets in cancer
Bioelectricity of Cancer, a special issue of the peer-reviewed journal Bioelectricity, has just been published. (2019-10-09)
New research uncovers how common genetic mutation drives cancer
A new, multicenter study led by Fred Hutchinson Cancer Research Center and Memorial Sloan Kettering Cancer Center determined how a single mutation in splicing factor 3b subunit 1 (SF3B1), the most frequently mutated splicing factor gene, drives the formation of many cancers. (2019-10-09)
Patient-derived organoids help predict how patients respond to chemotherapy
Researchers have created a test based on tumor organoids -- or 3D tissue cultures -- that can help predict how patients with advanced colorectal cancer (CRC) may respond to chemotherapy treatment. (2019-10-09)
Melanoma variability at the single-cell level predicts treatment responses
In a new study published in EBioMedicine, researchers with Moffitt Cancer Center's Donald A. (2019-10-08)
Study: Innovative pancreatic cancer treatment may rev up immune system
A research team at the University of Rochester Wilmot Cancer Institute reports that combining a type of radiation therapy with immunotherapy not only cures pancreatic cancer in mice, but appears to reprogram the immune system to create an 'immune memory' in the same way that a vaccine keeps the flu away. (2019-10-08)
Researchers discover critical process for how breast cancer spreads in bones
Researchers from the University of Notre Dame have identified a pair of proteins believed to be critical for spreading, or metastasizing, breast cancer to bone. (2019-10-07)
Meningioma molecular profile reliably predicts tumor recurrence
Researchers report tumor's molecular profiles that might better predict meningioma recurrence. (2019-10-07)
Scientists create brain-mimicking environment to grow 3D tissue models of brain tumors
Researchers have developed 3-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, that includes brain-derived extracellular matrix (ECM) -- the complex network of proteins and amino acids with bound sugars that not only provides support for surrounding neural tissue, but also helps to guide cell growth and development. (2019-10-04)
Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma
Here the researchers present in silico, in vitro, and mouse xenograft studies that suggest that specifically targeting HDAC2 reduces MDM2 expression and has anti-tumor affects in DDLPS. (2019-10-04)
New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses
The identification of oncogenic mutations has provided further insights into the tumorigenesis of meningioma and the possibility of targeted therapy. (2019-10-04)
New method to purify cell types to high purity
Current biology research relies on the ability to purify cell types using antibodies or transgenic constructs. (2019-10-03)
Large-scale mapping of protein networks behind tumor growth in the lungs
Researchers at the University of Copenhagen have used highly sophisticated molecular analyses to identify key proteins in the signaling pathways that cancers use to spread in the body. (2019-10-03)
New fluorescence method reveals signatures of individual microbes
University of Tsukuba researchers have developed a new method that reveals the unique fluorescence patterns produced by individual cells in mixtures of bacteria, yeast and fungi. (2019-10-03)
Discovery of new source of cancer antigens may expand cancer vaccine capabilities
For more than a decade, scientist Stephen Albert Johnston's team have pooled their energies to develop a vaccine to prevent cancer. (2019-10-02)
Engineered T cells may be harnessed to kill solid tumor cells
A new Tel Aviv University study finds that a form of immunotherapy used to treat the blood cancer leukemia may be effective in treating other kinds of cancer as well. (2019-10-02)
Pioneering red light-activated anti-tumor prodrug reduces side effects
Phorbiplatin, a new anti-cancer prodrug that can be controllably activated by red light was developed by a research team from City University of Hong Kong. (2019-10-02)
Patient cancer cells reliably grow on new 3D scaffold, showing promise for precision medicine
A new 3D structure for growing cell cultures could enable doctors to test medications on model tumors grown from a patient's own cells, according to results from a team of engineers and cancer researchers at the University of Michigan. (2019-10-02)
Fungal invasion of pancreas creates cancer risk
Certain fungi move from the gut to the pancreas, expand their population more than a thousand-fold, and encourage pancreatic cancer growth, a new study finds. (2019-10-02)
Collagen fibers encourage cell streaming through balancing act
Engineers from the McKelvey School of Engineering at Washington University have shown that the length of collagen fibers has a roll to play in the ability of normal cells to become invasive. (2019-10-01)
Novel strategy using microRNA biomarkers can distinguish melanomas from nevi
Melanoma is the least common but one of the most deadly skin cancers. (2019-09-30)
Delivery system can make RNA vaccines more powerful
MIT chemical engineers have developed a new type of lipid nanoparticle that can be used to deliver RNA vaccines. (2019-09-30)
Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth
A new discovery about pancreatic cancer sheds light on how the cancer fuels its growth and may help explain how promising cancer drugs work -- and for whom they will fail. (2019-09-26)
The FASEB Journal: PML as potential treatment for pancreatic cancer
A recent study in The FASEB Journal identifies a new mechanism of pancreatic tumors' resistance to chemotherapeutic treatment. (2019-09-26)
Researchers apply fat cells to deliver drug to suppress tumor growth
UCLA researchers have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. (2019-09-25)
Nanotechnology improves chemotherapy delivery
Michigan State University scientists have invented a new way to monitor chemotherapy concentrations, which is more effective in keeping patients' treatments within the crucial therapeutic window. (2019-09-25)
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