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Current Tumor News and Events

Current Tumor News and Events, Tumor News Articles.
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The evolution of brain tumors
Scientists from the German Cancer Research Center found in a recent study that only three different genetic alterations drive the early development of malignant glioblastomas. (2019-03-21)
High-fructose corn syrup enhances tumor growth in a mouse model of intestinal cancer
In a new study, researchers have found that consumption of high-fructose corn syrup can enhance tumor growth in mice that are genetically predisposed to develop intestinal cancer. (2019-03-21)
New drug combination shows promise for common pediatric brain tumor
A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models. (2019-03-21)
Researchers use radiomics to predict who will benefit from chemotherapy
Using data from computed tomography (CT) images, researchers may be able to predict which lung cancer patients will respond to chemotherapy, according to a new study. (2019-03-20)
Balance of two enzymes linked to pancreatic cancer survival
UC San Diego School of Medicine research sets the stage for clinicians to potentially one day use levels of a pancreatic cancer patient's PHLPP1 and PKC enzymes as a prognostic, and for researchers to develop new therapeutic drugs that inhibit PHLPP1 and boost PKC as a means to treat the disease. (2019-03-20)
Pushing MYC inhibition closer to the clinic
VHIO-born spin-off Peptomyc S.L. has developed and preclinically validated mini-protein MYC inhibitor as effective and tolerable against notoriously difficult-to-treat lung cancer subtype. (2019-03-20)
As if by magic: TGen develops program that lights up cancer-causing mutations
By conjuring the spell 'Lumos!' wizards in the mythical world of Harry Potter could light up the tip of their magic wands and illuminate their surroundings. (2019-03-20)
Precision oncology insights revealed for colorectal cancer
Findings published in the Journal of Clinical Oncology could help define strategies to more effectively treat colorectal cancer, the second leading cause of cancer death in the United States. (2019-03-19)
Preclinical data shows combination immunotherapy could stop liver cancer growth
New preclinical data from University of California San Diego School of Medicine and Moores Cancer Center offers proof-of-principle for a combination immunotherapy that suppresses tumor growth in the liver. (2019-03-13)
Stress hormones promote breast cancer metastasis
Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones. (2019-03-13)
Early-life exposure to microbiota restricts colon cancer later in life, study finds
Exposure to microbiota, or microorganisms such as bacteria, in the early stages of life plays a crucial role in establishing optimal conditions in the intestine that inhibit the development of colon cancer in adulthood, according to a study led by Georgia State University. (2019-03-13)
Small molecule inhibitors show treatment potential for EBV-associated cancers
Wistar researchers have created a drug candidate for cancers associated with Epstein-Barr Virus (EBV), the virus that causes infectious mononucleosis. (2019-03-06)
Nuclear medicine imaging monitors effectiveness of therapy for melanoma patients
Nuclear medicine imaging with PET/CT can monitor the effectiveness of immunotherapy treatment for metastatic melanoma and predict outcome. (2019-03-05)
Promising strategy to fight the most deadly brain tumor in children
A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma (DIPG) -- the most deadly brain tumor in children. (2019-03-04)
Shedding light -- literally -- on resistance to radiation therapy
A new Johns Hopkins study offers promise towards someday being able to non-invasively examine changes in cancerous tumors to determine whether they'll respond to radiation treatment, before treatment even begins. (2019-02-28)
Protein content as a marker for response to therapy in brain cancer
Brain tumors vary widely in how they respond to treatment. (2019-02-28)
Newly identified drug targets could open door for esophageal cancer therapeutics
Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School of Medicine. (2019-02-27)
Radiation contamination at a crematorium
Radioactive compounds known as radiopharmaceuticals are used in nuclear medicine procedures to diagnose and treat disease. (2019-02-26)
Better together: Mitochondrial fusion supports cell division
New research from Washington University in St. Louis shows that when cells divide rapidly, their mitochondria are fused together. (2019-02-26)
Origin of resistance to lung-cancer drug discovered
Researchers at Kanazawa University report in Nature Communications what causes some lung-cancer patients to have an intrinsic resistance to the drug osimertinib: AXL, a protein belonging to the class of receptor tyrosine kinases. (2019-02-25)
Mini tumors could help identify personalized treatments for people with rare cancers
UCLA scientists have developed a new method to quickly screen hundreds of drugs in order to identify treatments that can target specific tumors. (2019-02-25)
MTHFD2 mitochondrial metabolic enzyme maintains cancer stem-like cells
Tumor tissues include cancer stem-like cells (CSCs) that are responsible for recurrence and drug resistance. (2019-02-21)
WVU researcher explores what tumor cells and a healthy retina have in common
West Virginia University researcher Jianhai Du is parsing how the retina hijacks an energy-producing chemical reaction to churn out molecular building blocks to renew photoreceptor membranes that keep our vision sharp. (2019-02-21)
Insight into tumor-suppressive and tumor-promoting effects of cellular senescence
Wistar researchers have described a novel role of nicotinamide adenine dinucleotide (NAD+) metabolism in the ability of senescent cells to release tumor-promoting molecules. (2019-02-18)
Immune stimulant molecule shown to prevent cancer
An immune checkpoint molecule developed for cancer immunotherapy also protects against future development of multiple types of cancer when administered by itself. (2019-02-15)
New assay selects patients with lung cancer for treatment with immune checkpoint inhibitors
A report in The Journal of Molecular Diagnostics describes a novel and rapid approach for quantifying PD-L1 expression levels in tumors that requires only small amounts of tissue that can be collected using minimally invasive bronchoscopy techniques. (2019-02-13)
How breast tissue stiffening promotes breast cancer development
By examining how mammary cells respond in a stiffness-changing hydrogel, researchers discovered that several pathways work together to signal breast cells to turn cancerous. (2019-02-12)
Gene involved in colorectal cancer also causes breast cancer
Rare mutations in the NTHL1 gene, previously associated with colorectal cancer, also cause breast cancer and other types of cancer. (2019-02-11)
Case study documents bone cancer in 240-million-year-old stem-turtle
This research letter documents bone cancer in a 240-million-year-old stem-turtle from the Triassic period, helping to provide more data about the history of cancer in tetrapod evolution. (2019-02-07)
Combination treatment, diabetes drug and immunotherapy, may help to fight breast cancer
Researchers in Finland have discovered a drug combination that collaborates with the cancer cells' own MYC oncoprotein, which in large quantities causes self-destruction of the cancer cells. (2019-02-06)
Escort service: The role of immune cells in the formation of metastases
Tumor cells use a certain type of immune cells, the so-called neutrophils, to enhance their ability to form metastases. (2019-02-06)
A hidden route for fatty acids can make cancers resistant to therapy
Researchers from the lab of Prof. Sarah-Maria Fendt at the VIB-KU Leuven Center for Cancer Biology now demonstrate that certain tumor cells use an alternative -- previously unexplored -- pathway to produce fatty acids. (2019-02-06)
A breakthrough for brain tumor drug development
Glioblastoma is a devastating disease with poor survival stats due in part to a lack of preclinical models for new drug testing. (2019-02-05)
Enlarged prostate could actually be stopping tumor growth, simulations show
Computer simulations show for the first time that when a patient has history of an enlarged prostate, tumors in the prostate barely grow at all. (2019-02-04)
Drug target identified for chemotherapy-resistant ovarian, breast cancer
Researchers at Washington University School of Medicine in St. Louis may have found a path toward improving the effectiveness of chemotherapy in people with breast or ovarian cancer caused by defects in one of the BRCA genes. (2019-02-04)
Bacteria promote lung tumor development, study suggests
MIT cancer biologists have discovered a mechanism that lung tumors exploit to promote their own survival: The tumors alter bacterial populations within the lung, provoking the immune system to create an inflammatory environment that in turn helps the tumor cells to proliferate. (2019-01-31)
Study reveals how brain tumors escape the effects of antiangiogenic drugs
A study led by investigators from Massachusetts General Hospital and the University of Cyprus reveals details of a way the dangerous brain tumors called glioblastomas resist the effects of antiangiogenic drugs designed to cut off their blood supply, identifying what may be a new treatment target. (2019-01-30)
Researchers link overexpression of MDMX protein to metastasis of 3X negative breast cancer
In a newly published paper in the journal Breast Cancer Research, scientists at The Graduate Center of The City University of New York and Hunter College are the first to report that MDMX promotes metastasis of triple-negative breast cancer -- one of the most aggressive forms of the disease, and one that is more prevalent in young women and women of color. (2019-01-30)
New precision medicine procedure fights cancer, advances treatment for pets and humans
In a first-of-its-kind study, scientists at the University of Missouri have helped advance a patient-specific, precision medicine treatment for bone cancer in dogs. (2019-01-28)
The hitchhiker's guide to defeating glioblastoma
A team of investigators at Brigham and Women's Hospital and Harvard Medical School has begun looking at microRNAs in an entirely new way. (2019-01-25)
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