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Current Tumors News and Events

Current Tumors News and Events, Tumors News Articles.
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Study finds new way to make chemotherapy more effective against pancreatic cancer
Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. (2019-09-18)
Novel approach to ultrasound raises possibility of new medical applications
A new ultrasound technique provides a non-invasive way of assessing bone structure on the microscale. (2019-09-17)
Subgroup of colorectal cancer patients ID'd: Do poorly, could benefit from immunotherapy
While the medical community agrees immune cells inside a tumor leads to improved health outcome, for a subset of colorectal cancer patients, having too much of a good thing is a strong predictor of disease recurrence and reduced chances of survival. (2019-09-16)
Too much of a good thing: Overactive immune cells trigger inflammation
Scientists describe a previously unknown disorder of the immune system: in a distinct subset of immune cells from patients with primary immunodeficiency, cellular respiration is significantly increased. (2019-09-16)
New imaging technology could 'revolutionize' cancer surgery
Cancer treatment could be dramatically improved by an invention at the University of Waterloo to precisely locate the edges of tumors during surgery to remove them. (2019-09-16)
Tiny bubbles in our body could fight cancer better than chemo
Healthy cells in our body release nano-sized bubbles that transfer genetic material such as DNA and RNA to other cells. (2019-09-13)
Patients with metastatic colorectal cancer harboring certain BRAF mutations may respond to anti-EGFR
Patients with metastatic colorectal cancer harboring a subset of non-V600 mutations in the BRAF gene, known as class 3 BRAF mutations, were more likely to respond to anti-EGFR treatment. (2019-09-12)
Papillomaviruses may be able to be spread by blood
Researchers found that rabbit and mouse papillomaviruses could be transferred by blood to their respective hosts, raising the possibility that human papillomavirus (HPV) may also be transferable by blood in humans. (2019-09-11)
Breast cancer cells 'stick together' to spread through the body during metastasis
Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis. (2019-09-10)
Existing drug could treat aggressive brain cancer
A research team from the University of Georgia's Regenerative Bioscience Center has found that a compound molecule used for drug delivery of insulin could be used to treat glioblastoma, an aggressive, usually fatal form of brain cancer. (2019-09-10)
Liquid biopsies reveal genetic alterations linked to cancer drug resistance
New research shows that liquid biopsies taken from blood provide a more complete picture than traditional biopsy of both the genetic diversity of a patient's cancer and how tumors evolve drug resistance at the molecular level. (2019-09-09)
UTA scientist explores using nanoparticles to reduce size of deep-seated tumors
Another collaborative project from a nanoparticles expert at The University of Texas at Arlington has yielded promising results in the search for more effective, targeted cancer treatments. (2019-09-05)
Discovered a factor that predicts long survival in brain tumor
Researchers of the Josep Carreras Leukaemia Research Institute have discovered an epigenetic lesion that allows identifying those patients affected by brain tumors that have a longer life expectancy. (2019-09-03)
Delivering immunotherapy directly to brain tumors
A new study published this week gives insight into how cancer immunotherapies might one day be delivered directly to the brain in order to treat brain tumors. (2019-08-29)
Nanoparticles 'click' immune cells to make a deeper penetration into tumors
IBS scientists reported a novel targeting strategy that allows deep tumor penetration of drug-loaded nanoparticles. (2019-08-28)
A PoEM on breast cancer metastasis
When breast cancer cells spread through the body, they do so mainly through the lymph system that normally removes excess fluid and waste products from our tissues. (2019-08-28)
Gene mutations coordinate to drive malignancy in lung cancer
Scientists have shown exactly how mutations in two different genes coordinate to drive the development of malignant lung tumors, according to a new report in the open-access journal eLife. (2019-08-27)
Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy
Researchers show that heterogeneity of both breast cancer cells themselves and immune composition of the tumor microenvironment are important considerations for therapy. (2019-08-26)
Identification of all types of germ cells tumors
Germ cell tumors were considered very heterogeneous and diverse, until recently. (2019-08-26)
Ludwig study identifies an Achilles heel of many types of cancer
A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. (2019-08-22)
Texas A&M CVM study finds new pathway for potential glioblastoma treatment
A team led by Texas A&M University's College of Veterinary Medicine & Biomedical Sciences' (CVM) researcher Dr. (2019-08-21)
Laboratory studies identify a potential way to treat human cancers with ARID1A mutations
A new study shows that tumor cells depleted of ARID1A -- a protein that acts as a cancer suppressor -- become highly sensitive to anticancer poly ADP ribose polymerase (PARP) inhibitor drugs after radiation treatment. (2019-08-19)
MDM2 counteracts resistance to CDK4/6 inhibitors for melanoma therapy
A study from Vanderbilt-Ingram Cancer Center and the Department of Veterans Affairs led by Anna Vilgelm, MD, Ph.D., and Ann Richmond, Ph.D., has identified a possible second-line treatment for melanoma patients. (2019-08-15)
Study: Non-invasive electrical stimulation alters blood flow in brain tumors
Led by Emiliano Santarnecchi, Ph.D., principal investigator at the Berenson-Allen Center For Non-Invasive Brain Stimulation at BIDMC, the scientists demonstrated that applying low-intensity electrical stimulation to the brains of patients with tumors resulted in decreased blood flow within tumors while leaving the rest of the brain unchanged. (2019-08-15)
Nanoparticle therapy targets lymph node metastases
Metastasis, in which cancer cells break free from the primary tumor and form tumors at other sites, worsens the prognosis for many cancer patients. (2019-08-14)
Manipulating dose, timing of two therapies reduces relapse in mouse models of breast cancer
Changing the standard dose and timing of two therapies greatly cut tumor relapse and reduced side effects in mouse models of kinase mutated breast cancer and lung cancer, UT Southwestern Simmons Cancer Center researchers have found. (2019-08-09)
Single-cell sequencing reveals glioblastoma's shape-shifting nature
Glioblastoma, a cancer that arises in the brain's supporting glial cells, is one of the worst diagnoses a child can receive. (2019-08-09)
Moffitt researchers identify subtypes of squamous cell lung cancer
Despite improved knowledge of the molecular alterations in SCC, little is understood about how the alterations contribute to the development of the cancer and how potential vulnerabilities could be exploited to treat the disease. (2019-08-08)
Researchers take key step toward cancer treatments that leave healthy cells unharmed
Researchers have opened up a possible avenue for new cancer therapies that don't have the side effects that oftentimes accompany many current cancer treatments by identifying a protein modification that specifically supports survival of tumor cells. (2019-08-05)
Spacer protects healthy organs from radiation exposure during particle therapy
Kobe University and Alfresa Pharma Corporation develop a novel medical device with non-woven fabric style made of bioabsorbable material. (2019-08-05)
MSI detection via liquid biopsy shows high concordance with results from tissue samples
Incorporation of pan-cancer microsatellite instability (MSI) detection into the 74-gene panel Guardant360 liquid biopsy assay showed high concordance with matched tissue samples in nearly 1,000 patients. (2019-08-05)
Lymph nodes can predict survival in patients with esophageal cancer
It is difficult for physicians to estimate recurrence and survival in patients with esophageal cancer. (2019-07-29)
City of Hope study finds novel mechanism of action for NK cells in checkpoint inhibitor for cancer
City of Hope scientists have discovered that natural killer (NK) cells provide one reason why anti-PD-L1 antibodies might work when tumor cells do not express PD-L1. (2019-07-26)
To understand a childhood brain tumor, researchers turn to single-cell analysis
Investigators at St. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor. (2019-07-24)
Unlocking therapies for hard-to-treat lung cancers
Around 85 percent of lung cancers are classified as non-small-cell lung cancers, or NSCLCs. (2019-07-24)
Immune therapy takes a 'BiTE' out of brain cancer
Massachusetts General Hospital investigators have created a new method that could make immune therapy more effective again brain tumors and expand its use against other types of solid tumors. (2019-07-24)
Wavelength-encoded laser particles for massively multiplexed cell tagging
Researchers describe a new class of biocompatible probes, laser particles that can be inserted inside living cells. (2019-07-23)
'Trojan horse' anticancer drug disguises itself as fat
A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors. (2019-07-18)
Tightening the tumor-targeting abilities of checkpoint blockade immunotherapy
Seeking to improve upon existing checkpoint inhibitor therapies, scientists have developed a common checkpoint inhibitor (anti-PD-L1) in a nanoparticle formulation, which were activated specifically at tumor sites in mouse models of cancer. (2019-07-12)
Enzyme responsible for dangerous properties of brain tumor stem cells
The relapse of brain tumors after therapy is driven by cancer stem cells that were not affected by the treatment. (2019-07-11)
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