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Current Tumors News and Events, Tumors News Articles.
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Mirror image tumor treatment
Our immune system ought to be able to recognize and kill tumor cells. (2020-07-08)
A helping hand for cancer immunotherapy
Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. (2020-07-08)
Drug treatment could improve effectiveness of immunotherapy for cancer patients
The MDM2 gene promotes tumor growth and interferes with immunotherapy in some cancer patients -- a new study from a Brown University research team suggests that an MDM2-inhibiting drug could help address this problem. (2020-07-08)
Cancer cells make blood vessels drug resistant during chemotherapy
Scientists have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance. (2020-07-01)
The combination of four drugs at low doses is more effective in the treatment of a lu
The study, published in the Nature Communications journal, and led by the Netherlands Cancer Institute (NKI), has had the collaboration of researchers from IDIBELL/ICO and HUB. (2020-07-01)
Glowing dye may aid in eliminating cancer
When a solid cancer is surgically removed, any small piece that is left behind increases the chance of a local recurrence or spread. (2020-06-30)
New treatment strategy may benefit patients with brain cancer
A team led by investigators at Massachusetts General Hospital has uncovered a potentially promising strategy to treat gliomas with mutations in the IDH genes. (2020-06-30)
Protein derived from tick saliva proves effective in the treatment of equine skin cancer
Experiments were conducted by scientists affiliated with the Center of Excellence in New Target Discovery, a research center supported by FAPESP, involving five animals with spontaneous skin tumors. (2020-06-29)
St. Jude Cloud portal expands access to treasure trove of pediatric solid tumor data
St. Jude Children's Research Hospital develops the Childhood Solid Tumor Network data portal to speed discoveries and novel therapies for treatment of childhood solid tumors. (2020-06-26)
University of Cincinnati research uncovers clues in use of immunotherapy for breast cancer
UC researchers have found a potential new combination therapy for breast cancer that would integrate use of the body's immune system with targeted treatment for a particular protein that advances cancer. (2020-06-24)
Blocking a 'jamming signal' can unleash immune system to fight tumors
Yale researchers have discovered a ''jamming signal'' that blocks a powerful immune system stimulant called interleukin-18 (IL-18) from reaching tumors, including in cancers that are resistant to conventional immunotherapy treatments, they report June 24 in the journal Nature. (2020-06-24)
Tel Aviv University researchers destroy cancer cells with ultrasound treatment
An international research team has developed a noninvasive technology platform for gene delivery into breast cancer cells. (2020-06-24)
St. Jude creates resource for pediatric brain tumor research
Researchers worldwide can access orthotopic patient-derived xenograft models to speed discovery and test novel therapies for childhood brain tumors. (2020-06-23)
Biomarker test highly accurate in detecting early kidney cancer
A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists, say scientists from Dana-Farber Cancer Institute. (2020-06-22)
Patient-personalized sequencing pipeline steps up sensitivity of tumor DNA monitoring
A sequencing pipeline that integrates a patient's specific tumor genetic data boosts the sensitivity of tests that detect cancer cell DNA circulating in the blood, according to a newly published study. (2020-06-17)
Loss of lipid-regulating gene fuels prostate cancer spread
Johns Hopkins Kimmel Cancer Center researchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified a lipid-regulating protein that conveys what the researchers describe as ''superpowers'' onto prostate cancer cells, causing them to aggressively spread. (2020-06-16)
UCI researchers uncover cancer cell vulnerabilities; may lead to better cancer therapies
A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy. (2020-06-12)
Nanopatterned 'lab-on-a-chip' noninvasively detects early and advanced breast cancer
A scalable 'lab-on-a-chip' technology based on inkjet printing methods detected breast cancer in plasma samples from patients with more than 90% accuracy, according to a new study. (2020-06-10)
Oncotarget: Exploring the role of survivin in neuroendocrine neoplasms
Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes. (2020-06-10)
Photodynamic therapy used to treat ovarian cancer
Photodynamic therapy (PDT) is one of the most promising methods of treating localized tumors. (2020-06-08)
Some types of prostate cancer may not be as aggressive as originally thought
UCLA researchers analyzed gene-expression patterns in the most aggressive prostate cancer grade group and found that this grade of cancer can actually be subdivided into four subtypes with distinct differences. (2020-06-04)
'Terminator' protein halts cancer-causing cellular processes
New research from the lab of Hening Lin, professor of chemistry and chemical biology in the College of Arts and Sciences, finds that a protein called TiPARP acts as a terminator for several cancer-causing transcription factors, including HIF-1, which is implicated in many cancers, including breast cancer. (2020-06-03)
New CRISPR advance may solve key quandary
A mutation unique to certain cancer tumors is a potential homing beacon for safely deploying CRISPR gene editing enzymes to disarm DNA that makes cancer cells resistant to treatment, while ignoring the gene in normal cells where it's critical to healthy function, according to to a new study from ChristianaCare's Gene Editing Institute in the journal Molecular Cancer Research. (2020-06-02)
A boost for cancer immunotherapy
MIT engineers have found a way to boost the effectiveness of cancer immunotherapy drugs called checkpoint inhibitors. (2020-06-01)
Researchers identify a moving target in small cell lung tumors
About 15% of lung cancers are classified as small cell lung cancer. (2020-06-01)
Study reveals factors influencing outcomes in kidney cancer treated with immunotherapy
By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs. (2020-05-29)
Adoptive T-cell therapy ADP-A2M4 targeting MAGE-A4 shows early activity in patients with advanced solid tumors
The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center. (2020-05-29)
Mapping immune cells in brain tumors
It is not always possible to completely remove malignant brain tumors by surgery so that further treatment is necessary. (2020-05-28)
WPI-led research team shrinks breast cancer tumors in mice with targeted therapy
A team of researchers led by Worcester Polytechnic Institute Provost Wole Soboyejo attached anti-cancer agents to the hormone LHRH to create drugs that targeted triple-negative breast cancer, which typically does not respond to conventional targeted cancer therapies. (2020-05-28)
Novel targeted drug induced positive response for VHL-associated kidney cancer
In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)-associated renal cell carcinoma (RCC). (2020-05-28)
A comprehensive survey reveals bacteria are widespread in human tumors and differ by tumor type
Different human tumor types each harbor their own unique bacterial communities, researchers report in a new study that profiled the microbiomes of more than 1,500 individual tumors across seven types of human cancer - the most comprehensive tumor microbiome study to date. (2020-05-28)
Studying the development of ovarian cancer with organoids
Researchers from the group of Hans Clevers at the Hubrecht Institute have modeled the development and progression of high-grade serous ovarian cancer in mini-versions, or organoids, of the female reproductive organs of the mouse. (2020-05-27)
High-resolution 3D view inside tumors
Breast cancer is the most common cancer in women. But individual tumors can vary significantly, presenting different spatial patterns within their mass. (2020-05-26)
New double-contrast technique picks up small tumors on MRI
Early detection of tumors is extremely important in treating cancer. (2020-05-25)
New therapy for triple negative breast cancer
Researchers at the Principe Felipe Research Center (CIPF), the Universitat Politècnica de València (UPV), CIBER-BBN and the Institute for Research in Biomedicine (IRB) of Barcelona have inhibited tumor growth and reduced metastasis, as well as the toxicity of the antitumor drug Navitoclax in preclinical animal models of triple negative breast cancer (TNBC). (2020-05-25)
New model shows how cells that cause liver cancer are created
Scientists have discovered how liver cancer spreads, but they haven't yet learned how liver cancer cells are born. (2020-05-21)
T-cells could be made into better cancer killers by increasing their protein production
Hollings Cancer Center researchers at the Medical University of South Carolina have developed a technique to quantify protein production in immune cells known as T-cells, which typically target and kill cancer cells. (2020-05-20)
Why pancreatic ductal adenocarcinoma is so lethal
Pancreatic ductal carcinoma is a fast growing and invasive cancer, and now scientists understand the molecular dance that makes it so deadly. (2020-05-19)
New analytic tool designed to help guide precision oncology discovery and treatments
How can researchers and oncologists glean meaningful information from mounds of data to help guide cancer research and patient care? (2020-05-19)
Scientists identify promising immunotherapy combination for pediatric brain cancer
Scientists at Sanford Burnham Prebys have discovered that combining immunotherapy with a drug called tumor necrosis factor (TNF) eradicated a deadly type of pediatric brain tumor in mice. (2020-05-18)
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