Current Viruses News and Events

Current Viruses News and Events, Viruses News Articles.
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SARS-CoV-2 mutations do not appear to increase transmissibility
None of the mutations currently documented in the SARS-CoV-2 virus appear to increase its transmissibility in humans, according to a study led by UCL researchers, published in Nature Communications. (2020-11-25)

Grabbing viruses out of thin air
Materials that convert mechanical into electrical or magnetic energy could open the door to a future of wearable and structure-integrated virus sensors. (2020-11-25)

Engineered "stealth bomber" virus could be new weapon against metastatic cancer
Researchers at Emory and Case Western Reserve have re-engineered an oncolytic adenovirus. The resulting virus is not easily caught by parts of the innate immune system, making systemic delivery possible without arousing a massive inflammatory reaction. (2020-11-25)

New therapy for flu may help in fight against COVID-19
A new therapy for influenza virus infections that may also prove effective against many other pathogenic virus infections, including HIV and COVID-19, has been developed by Purdue University scientists. The Purdue team's approach uses a targeted therapy approach against the virus infections. (2020-11-24)

COVID's collateral damage: Germicidal lamps may damage corneas
In a paper published in the journal of Ocular Immunology and Inflammation, physicians from the Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine reported that several patients using germicidal lamps in an attempt to sanitize against the coronavirus, developed painful inflammation of the cornea, a condition called photokeratitis. These consumer-available ultraviolet (UV) emitting devices were being usedin an attempt toeliminate coronavirusfrom homes and offices. (2020-11-24)

T-cell abnormalities in severe COVID-19 cases
There appears to be some kind of T cell abnormality in critically ill COVID-19 patients but specific details are unclear. To shed some light on the problem, researchers performed a genetic analysis of T cells from lung tissue of COVID-19 patients. They found abnormalities that resulted in T cell overreaction that may cause severe pneumonia. The research is expected to lead to new methods for avoiding severe pneumonia caused by coronavirus infections. (2020-11-20)

A sulfur molecule to block the coronavirus
The cell membrane is impermeable to viruses: to get inside a cell, they have to exploit the biochemical properties of the membranes. The thiol-mediated uptake is one of the entry mechanisms. A research group from the University of Geneva has identified inhibitors of thhis cellular entry that block viruses expressing the SARS-CoV-2 proteins. The study paves the way for research into new antivirals. (2020-11-20)

Folding of SARS-CoV2 genome reveals drug targets -- and preparation for 'SARS-CoV3'
For the first time, an international research alliance has observed the RNA folding structures of the SARS-CoV2 genome with which the virus controls the infection process. Since these structures are very similar among various beta corona viruses, the scientists not only laid the foundation for the targeted development of novel drugs for treating COVID-19, but also for future occurrences of infection with new corona viruses that may develop in the future. (2020-11-20)

Coinfection: more than the sum of its parts
Infections with two pathogens pose a serious threat in the clinics. Researchers from Würzburg and Jena have developed a technique that provides new insights into this process and can be used as an early warning system. (2020-11-18)

Lurking in genomic shadows: How giant viruses fuel the evolution of algae
Together, Aylward and Moniruzzaman have recently discovered that endogenous viral elements that originate from giant viruses are much more common in chlorophyte green algae than previously thought. (2020-11-18)

Gut microbiome manipulation could result from virus discovery
Scientists have discovered how a common virus in the human gut infects and takes over bacterial cells - a finding that could be used to control the composition of the gut microbiome, which is important for human health. The Rutgers co-authored research, which could aid efforts to engineer beneficial bacteria that produce medicines and fuels and clean up pollutants, is published in the journal Nature. (2020-11-18)

Researchers recognize a viral protein's M.O. by just 3% of its size
Skoltech researchers and their colleagues from Russia, the US, and Sweden have described an unusual RNA polymerase that helps a poorly studied crAss-like bacteriophage transcribe its genes. They ''caught'' this enzyme by a tiny -- less than 3% of its size -- portion of the amino acid sequence that was similar to other RNA polymerases. (2020-11-18)

Researchers develop virus live stream to study virus infection
Researchers from the Hubrecht Institute and Utrecht University developed an advanced technique that makes it possible to monitor a virus infection live. The researchers from the groups of Tanenbaum and Van Kuppeveld expect that the technique can be used to study a wide variety of viruses, including SARS-CoV-2. The technique named VIRIM is very valuable for gaining insights in virus infection in the human body, which can lead to more targeted treatments. (2020-11-13)

Risk of AAV mobilization in gene therapy
New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy. These findings, which emphasize the need for mobilization resistant AAV vectors (2020-11-13)

Uracil switch in SARS-CoV-2 genome alters innate immune responses
Our bodies could be inducing mutations in the COVID-19 virus that activate immune cells to increase the production of pro-inflammatory molecules. (2020-11-11)

Cloth face masks that can be disinfected by the sun
During the COVID-19 pandemic, many people have become accustomed to wearing cotton face masks in public places. However, viruses and bacteria that stick to the mask could be transferred elsewhere when the wearer removes or touches it. Now, researchers reporting in ACS Applied Materials & Interfaces have developed a special type of cotton face mask that kills up to 99.9999% of bacteria and viruses within 60 minutes of daylight exposure. (2020-11-11)

MTU, UMass researchers preserve viral vaccines without refrigeration
Half of vaccines are wasted annually because they aren't kept cold. Michigan Tech and UMass Amherst chemical engineers have discovered a way to stabilize viruses in vaccines with proteins instead of temperature. (2020-11-11)

Researchers show safer, more targeted way to deliver CRISPR gene therapy
Biomedical researchers have come up with a novel way to use a beam of light to deliver CRISPR gene therapy molecules targeting illnesses. (2020-11-11)

RNA structures of coronavirus reveal potential drug targets
The SARS-CoV-2 coronavirus RNA genome structure was studied in detail by researchers from the University of Groningen, the International Institute of Molecular and Cell Biology in Warsaw, and Leiden University. The RNA structures are potential targets for the development of drugs against the virus. The results were published on 10 November as 'Breakthrough paper' in the journal Nucleic Acid Research. (2020-11-10)

Study identifies new "hidden" gene in COVID-19 virus
Researchers have discovered a new ''hidden'' gene in SARS-CoV-2--the virus that causes COVID-19--that may have contributed to its unique biology and pandemic potential. In a virus that only has about 15 genes in total, knowing more about this and other overlapping genes--or ''genes within genes''--could have a significant impact on how we combat the virus. (2020-11-10)

Researchers discover enzyme suppressing immune response to viral infections
Viruses such as HIV, hepatitis B and hepatitis C evade or disrupt the immune system to create persistent infections. These viruses remain a serious health threat, but researchers from the University of Missouri School of Medicine have discovered how an enzyme that regulates several cellular processes might be a key target to preventing viruses from disarming the human immune response. (2020-11-10)

$1 million to support manufacturing of COVID-19 treatments, vaccines at uOttawa, Ottawa Hospital
Researchers from the University of Ottawa and The Ottawa Hospital have been awarded $1,050,000 million from the Canada Foundation for Innovation to support facilities for manufacturing innovative treatments and vaccines for COVID-19. (2020-11-09)

Host genetic factors shape composition of virus communities
Plants can be infected by multiple viruses at once. However, the composition of the pathogen community varies, even if individuals belong to the same species and the same population. Ecologists at the University of Zurich have now shown that these differences are primarily due to genetic variation among the hosts. The loss of genetic diversity could thus render species more vulnerable to infections and extinction. (2020-11-05)

Sugar-coated viral proteins hijack and hitch a ride out of cells
Many viruses - including coronaviruses ¬- have protective outer layer made of proteins, fats and sugars. New research shows targeting sugar production has potential for broad-spectrum antiviral drugs (2020-11-05)

Plant viruses hijack the defence system of plants, but there might be a way to strike back
Recently discovered interactions between plant and viral proteins open up new avenues for making plants resistant to viruses, thus safeguarding crop yields in changing climate conditions. (2020-11-03)

Microfluidics helps MTU engineers watch viral infection in real time
Watching a viral infection happen in real time is like a cross between a zombie horror film, paint drying, and a Bollywood epic on repeat. Over a 10-hour span, chemical engineers from Michigan Tech watched viral infections happen with precision inside a microfluidics device and can measure when the infection cycle gets interrupted by an antiviral compound. (2020-11-02)

Criss-crossing viruses give rise to peculiar hybrid variants
In new research appearing in the journal mBio, Arvind Varsani and his colleagues investigate a recently discovered class of viruses that have taken the characteristic versatility of the viral world to new heights. Referred to as cruciviruses, these minute forms reveal a fusion of components from both RNA and DNA viruses, proving that these previously distinct genomic domains can, under proper conditions, intermingle, producing a hybrid or chimeric viral variant. (2020-10-31)

Study measures effectiveness of different face mask materials when coughing
A team of researchers have tested everything from t-shirts and socks to jeans and vacuum bags to determine what type of mask material is most effective at trapping the ultrafine particles which may contain viruses such as SARS-CoV-2, the virus which causes COVID-19. (2020-10-29)

Face mask aims to deactivate virus to protect others
Researchers have developed a face mask with an embedded antiviral layer that sanitizes the wearer's respiratory droplets to make them less infectious to others. (2020-10-29)

Model could improve design of vaccines, immunotherapies
Researchers have discovered a general property for understanding how immune cell receptors sense and respond to microbial signals, which could lead to more effective vaccines for both existing and novel viruses. (2020-10-27)

Coronaviruses are masters of mimicry, new study finds
Coronaviruses are adept at imitating human immune proteins that have been implicated in severe COVID-19 disease, a study from researchers at Columbia University has found. (2020-10-27)

T-Cells from recovered COVID-19 patients show promise to protect vulnerable patients from infection
T-cells taken from the blood of people who recovered from a COVID-19 infection can be successfully multiplied in the lab and maintain the ability to effectively target proteins that are key to the virus's function, according to a new study published Oct. 26, 2020 in Blood. (2020-10-26)

Can scientists take the STING out of common respiratory viruses?
University of North Carolina School of Medicine scientists have made a curious discovery about a well-known human protein that helps the immune system fight viral infections. The lab of Stan Lemon MD, and colleagues found that one class of viruses actually requires this protein to infect cells and replicate. (2020-10-26)

New COVID-19 related genes -- helpful and harmful -- found in massive screen
Researchers at Yale University and the Broad Institute of MIT and Harvard screened hundreds of millions of cells exposed to the COVID-19 and MERS viruses and identified dozens of genes that both enable the viruses to replicate in cells and also those that seem to slam the door on the virus. The pro-viral and anti-viral role of these genes will help guide scientists in development of new therapies to combat COVID-19, the researchers say. (2020-10-26)

Duke-NUS study uncovers why bats excel as viral reservoirs without getting sick
Study confirms bats adopt multiple strategies to reduce pro-inflammatory responses, thus mitigating potential immune-mediated tissue damage and disease. Findings provide important insights for medical research on human diseases. (2020-10-26)

New imaging method reveals HIV's sugary shield in unprecedented detail
Scientists from Scripps Research have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules that help shield HIV from the immune system. Mapping these shields will give researchers a more complete understanding of why antibodies react to some spots on the virus but not others, and may shape the design of new vaccines that target the most vulnerable sites on viruses. (2020-10-23)

A promising discovery could lead to better treatment for Hepatitis C
Virologists at Institut national de la recherche scientifique (INRS) have identified a critical role played by a cellular protein in the progression of Hepatitis C virus infection, paving the way for more effective treatment. No vaccine currently exists for Hepatitis C virus infection, which affects more than 130 million people worldwide and nearly 250,000 Canadians. Antivirals exist but are expensive and not readily available in developing countries, where the disease is most prevalent. (2020-10-22)

Details about broadly neutralizing antibodies provide insights for universal flu vaccine
New research from an immunology team at the University of Chicago may shed light on the challenges of developing a universal flu vaccine that would provide long-lasting and broad protection against influenza viruses. (2020-10-22)

Computational study reveals how Ebola nucleocapsid stabilizes
Scientists at the University of Delaware report a computational study of the Ebola virus nucleocapsid and show that the binding of the ssRNA allows the nucleocapsid to maintain its shape and structural integrity. (2020-10-20)

Researchers discovered the second 'key' used by the SARS-CoV-2 virus to enter into huma
To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including the respiratory tract, blood vessels and neurons. The breakthrough discovery was made by a German-Finnish team of researchers led by neuroscientists Mika Simons ,Technical University of Munich, Germany and virologist Giuseppe Balistreri, University of Helsinki, Finland. (2020-10-20)

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