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Current Zebrafish News and Events

Current Zebrafish News and Events, Zebrafish News Articles.
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Researchers discover how left-right information is integrated to correct organ positioning
Scientists from the Instituto de Neurociencias CSIC-UMH in Alicante, Spain, under the supervision of Professor Angela Nieto, have discovered the molecular mechanism that ensures the right equilibrium needed in left-right signaling cascade during development for the correct leftward positioning of the heart. (2019-10-17)
Startled fish escape using several distinct neuronal circuits
A fast knee-jerk 'ballistic' escape response and a more considered 'delayed' escape response are mediated by distinct and parallel neuronal pathways in zebrafish, according to a study published October 15, 2019 in the open-access journal PLOS Biology by Harold Burgess of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and colleagues. (2019-10-15)
mpacts of low-dose exposure to antibiotics unveiled in zebrafish gut
An antibiotic commonly found at low concentrations in the environment can have major impacts on gut bacteria, report researchers at the University of Oregon. (2019-10-10)
Need to balance guides development of limb-body coordination
The need to feel balanced drives the development of coordination between body and limbs as zebrafish larvae learn to swim, a new study finds. (2019-10-08)
Histone modifications are the influencers of zygotic genome awakening
Scientists at Tokyo Institute of Technology (Tokyo Tech) observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to 'histone H3', one of the proteins around which DNA is bound, play an important role in 'zygotic genome activation' or transition of control of zebrafish embryonic development from maternal material to the zygote. (2019-10-07)
How neural circuits form in a developing embryo
A new imaging method follows young neurons in a developing embryo as they progress from a messy jumble of cells into a coordinated control center. (2019-09-26)
Brain activity intensity drives need for sleep
The intensity of brain activity during the day, notwithstanding how long we've been awake, appears to increase our need for sleep, according to a new UCL study in zebrafish, published in Neuron. (2019-09-16)
Defective cilia linked to heart valve birth defects
Bicuspid aortic valve (BAV), the most common heart valve birth defect, is associated with genetic variation in human primary cilia during heart valve development, report Medical University of South Carolina researchers in Circulation. (2019-09-16)
How breast cancer uses exosomes to metastasize to the brain
In breast cancer, metastases to the brain often spell a death sentence; many women survive for less than a year after diagnosis. (2019-09-12)
Human developmental clock mimicked in a dish
Scientists at the Morgridge Institute for Research have created a new way to study developmental timing by using human stem cells to create a 'clock in a dish.' The model opens new research avenues and provides a way to replicate developmental disorders to better understand their cause. (2019-08-29)
Breaching the brain's defense causes epilepsy
Epileptic seizures can happen to anyone. But how do they occur and what initiates such a rapid response? (2019-08-26)
Study identifies mutations linked to familial pancreatic cancer
Study finds genetic mutations associated with hereditary forms of pancreatic cancer and mechanism by which these mutations may contribute to the development of tumors. (2019-08-15)
Inherited pancreatic cancer risk mutation identified
The discovery of the previously unknown mutation, reported in Nature Genetics by investigators from Dana-Farber/Brigham and Women's Cancer Center, could lead to routine testing of individuals with a strong family history of pancreatic cancer to determine if they carry the mutation, occurring in the gene known as RABL3. (2019-08-12)
Gut throws cells overboard when chemical insults build up
A Duke University team was testing more than 20 non-steroidal anti-inflammatory drugs (NSAID) in an attempt to make the zebrafish a new model for studying chemical injury in the gut. (2019-08-05)
Glowing cholesterol helps scientists fight heart disease
A newly developed technique that shows artery clogging fat-and-protein complexes in live fish gave investigators from Carnegie, Johns Hopkins University, and the Mayo Clinic a glimpse of how to study heart disease in action. (2019-07-31)
Mechanical forces control cell fate during brain formation
The study shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance between progenitor stem cells and differentiated neurons. (2019-07-29)
New studies suggest prenatal marijuana may be capable of causing FASD-like impairment
Whether alone or combined with alcohol, new studies included in Birth Defects Research just published by the Teratology Society with John Wiley & Sons, suggest marijuana exposure may be capable of triggering morphological and behavioral impairments similar to those seen with Fetal Alcohol Spectrum Disorders (FASD). (2019-07-23)
NIH publishes largest genomic study on type 2 diabetes in sub-Saharan African populations
Researchers at NHGRI have performed the largest GWAS study on type 2 diabetes in the sub-Saharan African populations, revealing an association between the disease and previously unlinked ZRANB3 gene. (2019-07-19)
Boosting the discovery of new drugs to treat spinal cord injuries using zebrafish
A research team led by Leonor Sa├║de, Principal Investigator at Instituto de Medicina Molecular, in partnership with the company Technophage, SA, has designed a simple and efficient platform that uses zebrafish to discover and identify new drugs to treat spinal cord lesions. (2019-07-19)
Survival of the zebrafish: Mate, or flee?
*Researchers have found that when making decisions that are important to the species' survival, zebrafish choose to mate rather than to flee from a threat. (2019-07-18)
Ancient epigenetic changes silence cancer-linked genes
A study in zebrafish indicates that some genes linked to cancers in humans have been strictly regulated throughout evolution. (2019-07-11)
Neural sleep patterns emerged at least 450 million years ago, Stanford researchers find
Researchers at the Stanford University School of Medicine have found that neural signatures in sleeping zebrafish are analogous to those of humans, suggesting that the brain activity evolved at least 450 million years ago, before any creatures crawled out of the ocean. (2019-07-10)
Determined DNA hunt reveals schizophrenia clue
An 18-year study using the DNA of thousands of people in India has identified a new clue in the quest for causes of schizophrenia, and for potential treatments. (2019-07-03)
Mutation discovery leads to precise treatment for child with severe lymphatic disorder
Faced with a preteen boy who had painful swelling and respiratory distress from a severe, deteriorating rare condition, researchers at Children's Hospital of Philadelphia identified the responsible gene mutation and harnessed that knowledge to develop a novel treatment that dramatically improved the problem. (2019-07-01)
Widespread disease diabetes: Why do beta cells refuse to release insulin?
One in 11 adults worldwide suffers from diabetes, and the number of diabetes patients is rising rapidly. (2019-06-26)
Changes in blood flow tell heart cells to regenerate
Altered blood flow resulting from heart injury switches on a communication cascade that reprograms heart cells and leads to heart regeneration in zebrafish. (2019-06-25)
Hearts and stripes: A tiny fish offers clues to regenerating damaged cardiac tissue
Zebrafish, a pet shop staple, may hold the clue for how hearts can heal from damage. (2019-06-25)
Settling the debate on serotonin's role in sleep
New research finds that serotonin is necessary for sleep, settling a long-standing controversy. (2019-06-24)
Scientists make a discovery that may explain some forms of stroke
Scientists from the University of Sheffield have discovered a novel behaviour of the blood vessels of the brain in zebrafish that may explain some forms of stroke in humans. (2019-06-21)
Frustrated fish give up thanks to glia, not just neurons
Giving up when efforts are futile depends on glial cells called radial astrocytes, highlighting a novel computational role for the underappreciated brain cells. (2019-06-20)
Tracking life's first step: Two molecules 'awaken' brand new genome
Within hours after fertilization, a unique genome forms from chromosomes contributed by the egg and sperm. (2019-06-17)
Increase in resolution, scale takes CT scanning and diagnosis to the next level
Researchers have developed a new, 3D tissue imaging technique, called X-ray histotomography. (2019-06-13)
Drug to treat malaria could mitigate hereditary hearing loss
The ability to hear depends on proteins to reach the outer membrane of sensory cells in the inner ear. (2019-06-11)
Life in Antarctica's ice mirrors human disease
Mapping tens of thousands of genes from a group of Antarctic fishes called notothenioids, a team of researchers has discovered that the massive amount of genetic change required for life in the Antarctic occurred long before the Antarctic cooled. (2019-06-10)
Researchers discover cells that change their identity during normal development
The ability of a developed cell to transform into another type of cell is exceptionally rare. (2019-06-04)
Zebrafish capture a 'window' on the cancer process
Cancer-related inflammation impacts significantly on cancer development and progression. New research has observed in zebrafish, for the first time, that inflammatory cells use weak spots or micro-perforations in the extracellular matrix barrier layer to access skin cancer cells. (2019-06-04)
How a zebrafish could help solve the mysteries of genetic brain disease
A close look at the rapidly developing zebrafish embryo is helping neuroscientists better understand the potential underpinnings of brain disorders, including autism and schizophrenia. (2019-05-23)
Newly discovered hybrid molecules could serve as a novel category of anti-cancer agent
Researchers from NYU Abu Dhabi's (NYUAD) chemistry program and colleagues from the University's biology program have developed and studied the biological activity of five new, metal-organic hybrid knotted molecules, termed metal-organic trefoil knots (M-TKs). (2019-05-22)
The neural mechanisms that inhibit slow muscle activity during fast swimming in fish
Using zebrafish larvae, Assistant Professor Yukiko Kimura and Professor Shin-Ichi Higashijima of the National Institute for Basic Biology in Japan have discovered neural mechanisms that suppress slow muscle activity in fish swimming at high speeds. (2019-05-22)
Zebrafish help researchers explore alternatives to bone marrow donation
UC San Diego researchers discover new role for epidermal growth factor receptor in blood stem cell development, a crucial key to being able to generate them in the laboratory, and circumvent the need for bone marrow donation. (2019-05-20)
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