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Forensic photography brings color back to ancient textiles
Archaeologists are now turning to forensic crime lab techniques to hunt for dyes, paint, and other decoration in prehistoric textiles. Although ancient fabrics can offer clues about prehistoric cultures, often their colors are faded, patterns dissolved, and fibers crumbling. Forensic photography can be used as an inexpensive and non-destructive tool to analyze these artifacts more efficiently, according to new Ohio State University research. (2007-02-07)

Blazing the Trail receives the IAA Luigi Napolitano Award
Mike Gruntman, professor and chair of astronautics at the University of Southern California, received the Luigi Napolitano Award (2006) from the International Academy of Astronautics for his book, (2006-09-26)

Ball or stuffed toy -- Do dogs 'know' what they're smelling?
Dogs' excellent sense of smell is well-known, whether it is in the context of searching for people or for contraband substances. However, the question of how dogs understand what they perceive with their sense of smell has largely been unexplored. In a study published today in the Journal of Comparative Psychology, scientists investigated this question and found evidence that dogs create a 'mental representation' of the target when they track a scent trail. (2018-03-05)

Pretreating rogue cancer cells with aspirin cripples their resistance to targeted therapy
In a study published in the Dec. 9 issue of the Journal of Biological Chemistry, University of Pittsburgh researchers report that aspirin, combined with a promising new cancer therapy known as TRAIL, can induce cancer cells that were previously resistant to TRAIL therapy to self-destruct. The investigators say that aspirin could become a routine, low-cost therapy for helping to prevent the recurrence of many aggressive cancers, such as prostate and colon cancers. (2005-12-12)

Two-stage nanoparticle delivery of piperlongumine and TRAIL anti-cancer therapy
New combination approach of nanoparticles and liposomes successfully deliver a potent TRAIL sensitizer followed by the anti-cancer protein TRAIL. (2016-05-20)

New technique targets specific areas of cancer cells with different drugs
Researchers have developed a technique for creating nanoparticles that carry two different cancer-killing drugs into the body and deliver those drugs to separate parts of the cancer cell where they will be most effective. (2014-01-06)

Immunex Corporation and Genentech, Inc. join forces to develop TRAIL/Apo2L in cancer
Immunex Corporation and Genentech, Inc. announced today that the two companies agreed to jointly develop TRAIL/Apo2L, an entirely new approach to research in the fight against cancer. (1999-06-01)

Ancient Greek Text Shows Musical View Of Pregnancy According To Translation By University Of Cincinnati Professor
An ancient Greek medical text edited and translated for the first time by University of Cincinnati associate professor of classics Holt Parker demonstrates how little the anicent Greeks knew about pregnancy. In a presentation at the Archaeological Institute of America, Parker reported that the ancient Greeks believed the development of a baby followed patterns reflected in musical harmony and the universe. (1997-12-29)

Scripps Research Institute chemists discover structure of cancer drug candidate
Chemists at The Scripps Research Institute have determined the correct structure of a highly promising anticancer compound approved by the US Food and Drug Administration for clinical trials in cancer patients. The new report, published this week by the international chemistry journal Angewandte Chemie, focuses on a compound called TIC10. (2014-05-19)

Piggy-backing proteins ride white blood cells to wipe out metastasizing cancer
Cornell biomedical engineers have discovered a new way to destroy metastasizing cancer cells traveling through the bloodstream -- lethal invaders that are linked to almost all cancer deaths -- by hitching cancer-killing proteins along for a ride on life-saving white blood cells. (2014-01-06)

Sniffers show that humans can track scents, and that two nostrils are better than one
Do animals use their two nostrils to locate scents in the same way they use two ears to locate sounds? UC Berkeley neuroscientists Noam Sobel and Jess Porter set out to test that question, using human volunteers on all fours to track a chocolate scent through the grass. With other senses blocked by gloves, earplugs and a blindfold, they were able to track scents and did better with two open nostrils than one. (2006-12-18)

A protein called cFLIP makes tumor cells in breast cancer resistant to treatments
This finding might very useful for scientists, that could design cancer therapies aimed at interfering the action of this protein. Such was the conclusion drawn by the researchers at the Andalusian Institute for Molecular Biology and Regenerative Medicine, in collaboration with the University of Granada. (2010-12-14)

Tiny footprints, big discovery: Reptile tracks oldest ever found in grand canyon
UNLV geologist Stephen Rowland discovered that a set of 28 footprints left behind by a reptile-like creature 310 million years ago are the oldest ever to be found in Grand Canyon National Park. (2018-11-08)

Discovering the birth of an asteroid trail
Unlike comets, asteroids are not characterised by exhibiting a trail, but there are now ten exceptions. Spanish researchers have observed one of these rare asteroids from the Gran Telescopio Canarias (Spain) and have discovered that something happened around the 1st July 2011 causing its trail to appear: maybe internal rupture or collision with another asteroid. (2013-02-21)

Gene therapy establishes a TRAIL to arthritis treatment
In the November 3 issue of the Journal of Clinical Investigation, John Mountz and colleagues from the University of Alabama at Birmingham describe a gene-modified cell therapy utilizing the TRAIL molecule that successfully limits the incidence and severity of arthritis in a mouse model of collagen-induced arthritis and joint inflammation. The regime represents a therapeutic option for systemic rheumatic diseases. (2003-11-03)

First report that apoptotic and anti-angiogenic therapies work better together than alone
American researchers have found that giving a combination of imantanib and a drug that induces cell death was better at inhibiting the growth of Ewing's sarcoma in mice than either therapy on its own, according to research presented at the 18th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Prague on Friday. (2006-11-10)

Children in low-income neighborhood with special walking/bike trail exercised more
Children living in a neighborhood designed with a special bike trail were three times as likely as those in a traditional neighborhood to engage in vigorous physical activity, according to new research presented at the American Heart Association's Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2012 Scientific Sessions. (2012-03-15)

UT historian explores role of small villages in ancient Near East
A University of Tennessee, Knoxville, archaeologist who excavates ancient villages in the Near East has received a grant to reshape the modern understanding of the region's political, economic and social structure by studying its smallest rural settlements. (2011-02-07)

Double quantum dots control Kondo effect in nanoscience study
Two quantum dots connected by wires could help scientists better control the Kondo effect in experiments, according to a study by Ohio University and University of Florida physicists published in a recent issue of Physical Review Letters. (2006-09-14)

Scientists harvest answers from genome of grain fungus
Evil forces thrive in an unstable environment. At least, that's the picture being painted in the first waves of data being reaped from the genome sequence of the fungal plant pathogen, Fusarium graminearum. The sequencing has provided scientists a road map to someday combat a fungus that infects wheat and barley crops, rendering them unusable. (2007-09-06)

Human DNA uncovered in caves without bones
In cave sediments lacking skeletal remains, scientists report having found DNA from ancient humans. (2017-04-27)

The phantom chorus: birdsong boosts human well-being in protected areas
Although many studies have found that humans benefit from spending time in nature, few studies have explored why. Researchers hid speakers that played recorded songs from a diverse group of birds on two sections of trails in Colorado. Hikers who heard the bird songs reported a greater sense of well-being than those who didn't. The survey results showed that both the sounds themselves and people's perception of biodiversity can increase humans' feelings of well-being. (2020-12-15)

Planning processes for Chicago's 606 Trail spawned gentrification, study finds
In a paper published in the journal Cities, Alessandro Rigolon, a professor of recreation, sport and tourism at the University of Illinois, and University of Colorado urban and regional planning professor Jeremy Nemeth examined the planning processes associated with the 606 Trail and conclude that these processes may have made gentrification the most likely outcome. (2018-12-07)

Cell-death receptor links cancer susceptibility and inflammation
Researchers demonstrated for the first time a link between cell-death-inducing TRAIL's receptor and cancer susceptibility. Unexpectedly, they also found a connection -- via TRAIL -- between inflammation and cancer susceptibility. (2007-12-27)

Scientists believe ancient arachnids may have spun silk like modern spiders
Geologists at Ohio State University have found evidence of silk spinning structures on the fossilized body of a long-extinct relative of modern spiders, one that lived 55 million years before the first dinosaurs. The 300-million-year-old Aphantomartus pustulatus. The 300-million-year-old penny-sized creature, called Aphantomartus pustulatus, is a trigonotarbid -- part of an ancient group of arachnids that were among the first animals to colonize land. (2003-11-05)

A site to be seen: Ancient earthworks electronically rebuilt, to become a traveling exhibit
The Midwest's immense earthworks, structures built by ancient Native American cultures, have been all but lost to plow and pavement. No longer. An ambitious effort by the University of Cincinnati has rebuilt the mounds of two millennia ago. These virtual earthworks will soon travel the state and are later expected to travel the nation. (2006-04-19)

ONC201 kills breast cancer cells in vitro by targeting mitochondria
'Our work identifies a novel mechanism of ONC201 cytotoxicity that is based on the disruption of mitochondrial function, leading to ATP depletion and cell death in cancer cells that are dependent on mitochondrial respiration. Our study also suggests that cancer cells that are dependent on glycolysis will be resistant to ONC201' Dr. Stanley Lipkowitz, Chief, Women's Malignancies Branch, NCI. (2018-05-08)

CK2 protein sustains colon cancer cells by sabotaging ability to commit suicide
A protein called CK2 plays a deadly role in colorectal carcinoma by blocking the ability of these tumors to activate a natural self-destruct mechanism that would clear this cancer from the body. This finding, by researchers at St. Jude Children's Research Hospital, is currently published in the online edition of Oncogene. (2005-02-23)

Penn researchers identify new combination therapy that promotes cancer cell death
To test the ability of combined therapy, researchers administered TRAIL, a tumor necrosis factor, and sorafenib, an inhibitor currently used to treat renal cancer, to mice with colon carcinomas. It reduced the size of tumors in mice with few side effects (2007-07-16)

New test for ancient DNA authenticity throws doubt on Stone Age wheat trade
A new method reliably tests whether DNA shows ancient or modern patterns of biochemical change. (2015-11-03)

Earliest animal footprints ever found -- discovered in Nevada
The fossilized trail of an aquatic creature suggests that animals walked using legs at least 30 million years earlier than had been thought. The tracks -- two parallel rows of small dots, each about 2 millimeters in diameter -- date back some 570 million years, to the Ediacaran period. (2008-10-05)

Ancient Babylonians used geometry to track Jupiter
Analysis of ancient Babylonian tablets reveals that, to calculate the position of Jupiter, the tablets' makers used geometry, a technique scientists previously believed humans had not developed until at least 1,400 years later, in 14th century Europe. (2016-01-28)

Ancient proteins offer clues to the past
Archeologists once relied solely on artifacts, such as skeletal remains, fossils and pottery sherds, to learn about past species and cultures. Today's scientists can also study ancient proteins to paint a more complete picture of the people who lived at archeological sites, and the plants and animals they raised and ate, according to an article in Chemical & Engineering News (C&EN), the weekly news magazine of the American Chemical Society. (2019-05-22)

Scientists develop new method for studying early life in ancient rocks
Scientists have developed a new method for detecting traces of primordial life in ancient rock formations using potassium. (2019-07-08)

Rising mountains, cooling oceans prompted spread of invasive species 450 million years ago
New Ohio University research suggests that the rise of an early phase of the Appalachian Mountains and cooling oceans allowed invasive species to upset the North American ecosystem 450 million years ago. (2013-08-21)

An algorithm that explains how ants create and repair trail networks
Observing ants in the trees of a tropical forest, Professor Deborah Gordon recorded how, without a plan, the ants make and maintain their networks -- and how they repair the network when it is ruptured. (2017-10-02)

Meet 'Henry and Nick,' seals featured in Science study
A new experiment shows how harbor seals use their hyper- sensitive whiskers to detect hydrodynamic fish trails, a unique way to track prey in murky waters. (2001-07-05)

Jupiter's moons create uniquely patterned aurora on the gas giant planet
New images from the Juno spacecraft show an unusual 'footprint' of Jupiter's moons on their parent planet's aurora. (2018-07-05)

Asian longhorned beetles pheromone could be used to manage pest
Female Asian longhorned beetles lure males to their locations by laying down sex-specific pheromone trails on tree surfaces, according to an international team of researchers. The finding could lead to the development of a tool to manage this invasive pest that affects about 25 tree species in the United States. (2014-02-13)

Rebel historians coming to Orange County
Three of the most renowned authors and researchers in the field of alternative history will be speaking this fall at the (2006-08-03)

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