Antibiotic Resistance Current Events | Page 23

Antibiotic Resistance Current Events, Antibiotic Resistance News Articles.
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Breaking the barrier: Discovery of anti-resistance factors and novel ocean drugs
Investigations into coral disease, red tides and other marine environmental issues have led to discoveries of new chemicals as a source for pharmaceuticals. These chemicals function as antibiotics for microorganism providing survival advantages and may be usable in human health care. We believe that one could apply many of these chemical mechanisms or novel pharmaceuticals to human disease resulting in a number of alternatives to deal with growing antibiotic resistance. (2009-02-13)

Single-dose antibiotics reduce appendectomy complications
A single dose of antibiotics may be just as effective as multiple doses in preventing infections after an appendectomy, a new research review confirms. The review found that antibiotic injections do work no matter how diseased the appendix was or whether it was diseased at all. This is significant, because some surgeons contend that antibiotics should be used only when the appendix is at a more advanced stage of disease. (2005-07-19)

Antibiotics not always beneficial for childhood ear infections
More children are treated in the U.S. with antibiotics for inflammation of the middle ear, or otitis media, than any other child health problem. More than five million cases are diagnosed every year. But now, a scholarly review of over one hundred studies by a U.Va. pediatrician concludes that antibiotics help only one in eight children with ear infections. (2002-10-10)

Study examines three-day antibiotic regimens for treating bladder infection in women
A three-day regimen of the antibiotic amoxicillin-clavulanate is not as effective as ciprofloxacin at treating an uncomplicated bladder infection in women, according to a study in the February 23 issue of JAMA. (2005-02-22)

Fish tale: New study evaluates antibiotic content in farm-raised fish
In a new study, Hansa Done, Ph.D. candidate, and Rolf Halden, Ph.D., researchers at Arizona State University's Biodesign Institute, examine antibiotic use in the rapidly expanding world of global aquaculture. (2014-10-20)

Improved drug coverage under Medicare associated with increases in antibiotic use
Antibiotic use appears to have increased among older adults whose prescription drug coverage improved as a result of enrolling in Medicare Part D, with the largest increases for broad-spectrum, newer and more expensive drugs, according to a report in the Aug. 9-23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. (2010-08-09)

Distinguishing deadly Staph bacteria from harmless strains
To better understand the pathogenic bacteria Staphylococcus aureus and develop more effective treatments, University of California San Diego researchers examined the Staph 'pan-genome' -- the genomes of 64 different strains that differ in where they live, the types of hosts they infect and their antibiotic resistance profiles. This effort, published June 6 by PNAS, places all Staph genes into one of two categories: the core genome or the dispensable genome. (2016-06-06)

Battling superbugs
Two new technologies from researchers at MIT could enable novel strategies for combating drug-resistant bacteria. (2014-09-21)

Distinguishing resistance from resilience to prolong antibiotic potency
Biomedical engineers at Duke University have experimentally shown that there is more than one flavor of antibiotic resistance. Distinguishing resistance, where individual cells shrug off antibiotics, versus resilience, where a bacterial community's population crashes before adapting to disable the antibiotic, could help keep first-line antibiotics in our medical arsenal. (2018-12-05)

Drug-resistant staph bacteria prevalence higher in young children living with hog workers
Young children who reside with adults who work on large industrial hog operations in rural North Carolina had a higher prevalence of antibiotic-resistant in their nasal passages than children who live with adults who live in the same community but do not work on such operations, a new study suggests. (2016-10-18)

Cystitis treatment: Back to the 1950s
Doctors prescribe antibiotic treatments from the 1950s to fight antibiotic resistance. But these 'old' antibiotics were not tested in the same way as their modern counterparts before being put on the market. Doctors from UNIGE and HUG analyzed two antibiotics used against uncomplicated urinary tract infections. They discovered that the most widely prescribed antibiotic today does not meet the expected success rate, while the second most commonly prescribed antibiotic seems as effective as the newer drugs. (2018-05-14)

Queen's University in €6m bid to find new Cystic Fibrosis treatments
The new global program, known as CF Matters, aims to develop personalized antibiotic treatments for these chest infections. The work could revolutionize the practice of antibiotic prescription and limit resistance to the drugs globally. (2013-10-29)

Virus found to carry antibiotic against E. coli
Part of a small virus that attacks only bacteria acts like an antibiotic to destroy E. coli, researchers with the Texas Agricultural Experiment Station have found. A report on the antibiotic action of the small virus, (2001-06-21)

Resistance to last resort drug arose in patient over 3 weeks
French investigators have described development of resistance to one of the last resort therapies used to treat extremely drug-resistant Pseudomonas aeruginosa. That resistance arose in a single patient over a scant 22 days. They subsequently identified the single nucleotide mutation in P. aeruginosa that caused the resistance. (2019-10-21)

Nanomesh drug delivery provides hope against global antibiotic resistance
Flinders University researchers and collaborators in Japan have produced a nanomesh that is capable of delivering drug treatments. (2019-10-16)

Gonorrhoea strains across Europe becoming more susceptible to main treatment options
According to test results from the annual European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP), resistance levels to the main antimicrobials used for treatment of gonorrhoea infection have seen an encouraging decrease since 2010. However, resistance to one antibiotic agent which is part of the suggested dual therapy of gonorrhoea remains high and threatens the effectiveness of this regimen. (2017-09-13)

'Programmable' antibiotic harnesses an enzyme to attack drug-resistant microbes
Conventional antibiotics are indiscriminate about what they kill, a trait that can lead to complications for patients and can contribute to the growing problems of antibiotic resistance. But a a 'programmable' antibiotic being developed at Rockefeller would selectively target only the bad bugs, particularly those harboring antibiotic resistance genes, and leave beneficial microbes alone. (2014-10-05)

Want to beat antibiotic-resistant superbugs? Rethink that strep throat remedy
Antibiotics could become nearly useless by mid-century against intense infections due to bacteria evolving antibiotic resistance. And alternative treatments haven't been able to replace antibiotics in those big infections. It's time for a rethink: try reducing antibiotic use for small infections and find alternate remedies for them instead to slow the evolution of resistance. (2017-12-28)

Frequent traveller: Dysentery-causing bacteria spreading from Europe to Australia
Researchers have found that a strain of dysentery-causing bacterium that originated from Europe centuries ago is spreading rapidly to Australia and some developing countries. (2012-08-07)

Study shows rise in antibiotic resistant pediatric head and neck infections
A report by researchers in the Jan. 19, 2009, Archives of Otolaryngology -- Head and Neck Surgery shows that there was nationwide increase in the prevalence of pediatric methicillin-resistant Staphylococcus aureus head and neck infections from January 2001 to December 2006. (2009-01-19)

Bacteria-infecting viruses exacerbate chronic infections in cystic fibrosis
A study of samples from 92 patients with cystic fibrosis (CF) has revealed that certain bacteriophages -- viruses that infect bacteria -- worsen the severity of bacterial infections associated with the disorder. (2019-04-17)

How antibiotics help spread resistance
Bacteria can become insensitive to antibiotics by picking up resistance genes from the environment. Unfortunately for patients, the stress response induced by antibiotics activates competence, the ability of cells to take up and integrate foreign DNA, in microorganisms. Microbiologists from the University of Groningen (UG) and the University of Lausanne now describe a new mechanism by which Streptococcus pneumoniae can become competent, and why biofilms may be important in this process. (2018-11-27)

An unusual form of antibiotic resistance in pandemic cholera
Researchers at the University of Georgia have now shown that the enzyme that makes the El Tor family of V. cholerae resistant to those antibiotics has a different mechanism of action from any comparable proteins observed in bacteria so far. Understanding that mechanism better equips researchers to overcome the challenge it presents in a world with increasing antibiotic resistance. The results of this research are published in the Dec. 22 issue of the Journal of Biological Chemistry. (2018-01-03)

Identified the component that allows a lethal bacteria to spread resistance to antibiotics
A study performed at the Institute for Research in Biomedicine (IRB Barcelona) and involving the collaboration of the Centro de Investigaciones Biológicas (CIB-CSIC) in Madrid has identified the key component of the machinery that S. aureus uses to acquire and transfer genes that confer resistance to antibiotics. (2017-07-26)

Slaying bacteria with their own weapons
A novel antibiotic delivery system would exploit small molecules called siderophores that bacteria secrete to scavenge for iron in their environments. Each bacterium has its own system of siderophores, which it pumps across its cell membrane before releasing the iron the siderophore holds. If an antibiotic were linked to one of these scavenger molecules, it would be converted into a tiny Trojan horse that would smuggle antibiotics inside a bacterium's cell membrane. (2014-06-26)

Molecular machinery that makes potent antibiotic revealed after decades of research
Scientists at Rutgers and universities in Russia, Poland and England have solved a nearly 30-year mystery -- how the molecular machinery works in an enzyme that makes a potent antibiotic. The findings, which appear in the journal Molecular Cell, provide the tools to design new antibiotics, anticancer drugs and other therapeutics. (2019-01-17)

Institute for Biomedical Sciences researcher gets $1.6 million to develop anti-inflammatory drug
Dr. Jian-Dong Li, a professor and director of the Institute for Biomedical Sciences at Georgia State University and a Georgia Research Alliance Eminent Scholar in Inflammation and Immunity, has received a five-year, $1.6 million federal grant to develop novel anti-inflammatory therapeutics against middle-ear infections. (2015-07-01)

Putting bacterial antibiotic resistance into reverse
The use of antibiotics to treat bacterial infections causes a continual and vicious cycle that leads to the emergence and spread of resistant strains. What if it didn't have to be this way? One researcher explains how it could work. (2010-04-25)

Study: AIDS-immunocompromised populations see more antibiotic-resistant infections
Populations with a high prevalence of AIDS-immunocompromised people are more likely to see the emergence of antibiotic-resistant bacterial infections, according to a study coauthored by researchers at the University of Tennessee, Knoxville, and published in PLOS One. (2019-03-26)

Comeback of an abandoned antibiotic
In less-developed countries, inexpensive and well-tolerated antibiotics for therapy of streptococcal infections are often not available. Scientists of the HZI in Germany have discovered that trimethoprim may provide an option. Contrary to a long-held belief, the bacteria are not generally resistant to this agent. In their latest publication the scientists demonstrated three pathways for the development of resistance -- meaning that streptococci can easily become resistant to the antibiotic and pass on this trait quickly. (2014-03-19)

Researchers find antibiotic resistant genes prevalent in groundwater
The spread of antibiotic resistant genes (ARGs) through the water system could put public safety at-risk. Researchers studied and compared samples from an advanced groundwater treatment facility in California and groundwater aquifers to detect differences in ARG concentrations. They found that the advanced groundwater treatment facility reduced nearly all targeted ARGs to below detection limits, but groundwater samples had a ubiquitous presence of ARGs in both control locations and locations recharged with water from the advanced water treatment facility. (2019-10-04)

Antibiotics continue to be prescribed at high rate for bronchitis, contrary to guidelines
Despite clear evidence of ineffectiveness, guidelines and more than 15 years of educational efforts stating that the antibiotic prescribing rate for acute bronchitis should be zero, the rate was about 70 percent from 1996-2010 and increased during this time period, according to a study in the May 21 issue of JAMA. (2014-05-20)

RI Hospital receives $500,000 CDC grant to research new approach for combating antibiotic resistance
The Centers for Disease Control and Prevention (CDC) has awarded a $519,344 grant to Rhode Island Hospital to study the microbiome (bacteria that inhabit the body) of patients exposed to antibiotics to predict which are at most risk of acquiring multidrug-resistant bacteria. (2016-10-12)

Bacteria 'trap' could help slow down antibiotic resistance
Scientists have developed a new and faster test for identifying how single bacteria react to antibiotics, which could help in the fight against antimicrobial resistance. (2019-03-14)

One quarter of bacterial pathogens can spread antibiotic resistance directly to peers
Biomedical engineers at Duke University have demonstrated that at least 25 percent of antibiotic-resistant pathogenic bacteria found in clinical settings are capable of spreading their resistance directly to other bacteria. At the same time, the study shows that, despite common beliefs, the use of antibiotics does not significantly affect the rate at which the genes responsible for resistance are swapped between bacteria. (2020-01-29)

Drug-resistant genes spread through environment, not meat products
A current focus for policy-makers is to reduce antibiotic use in livestock to curb the spread of drug-resistant bugs. New findings show that traffic from humans to animals, and back to humans via the environment, should be a new focus for research. (2016-03-08)

Antimicrobial Resistance: Issues And Options
Fighting the problem of antibiotic resistance will require a better system of surveillance, as well as increased efforts to prolong the effectiveness of existing antibiotics and to develop new drugs, says a new report from the Institute of Medicine. (1998-05-14)

Unravelling the secret of antibiotic resistance
Scientists from the University of Leeds have solved a 25-year-old question about how a family of proteins allow bacteria to resist the effects of certain antibiotics. (2016-03-22)

Drug-resistant bacteria lurk in subway stations, high school students discover
Forget commuters and rats, New York City's subway system is crowded with microbes. After spending her vacation swabbing benches and turn styles beneath the city, high school student Anya Dunaif, a participant in Rockefeller's Summer Science Research Program found bacteria impervious to two major antibiotics. (2015-02-05)

Researchers discover new ways to treat chronic infections
Researchers at Binghamton University, State University of New York, have identified three key regulators required for the formation and development of biofilms. The discovery could lead to new ways of treating chronic infections. (2009-12-18)

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