Antibiotic Resistance Current Events | Page 25

Antibiotic Resistance Current Events, Antibiotic Resistance News Articles.
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MRSA eliminated by copper in live global broadcast
A live broadcast from the University of Southampton today highlighted the effectiveness of antimicrobial copper in preventing the spread of antibiotic-resistant organisms, such as MRSA, in hospitals. (2011-04-04)

Molecular doorstop could be key to new tuberculosis drugs
In discovering how an antibiotic kills the bacteria that cause tuberculosis, scientists open the door to new treatments for the disease -- and possibly others, as well. (2018-03-19)

Forestalling pesticide, antibiotic resistance possible, theory predicts
For years, farmers and agribusinesses have talked about being on the (2001-08-21)

Oil and gas wastewater spills alter microbes in West Virginia waters
Wastewater from oil and gas operations -- including fracking for shale gas -- at a West Virginia site altered microbes downstream, according to a Rutgers-led study. The study, published recently in Science of the Total Environment, showed that wastewater releases, including briny water that contained petroleum and other pollutants, altered the diversity, numbers and functions of microbes. The shifts in the microbial community indicated changes in their respiration and nutrient cycling, along with signs of stress. (2017-02-23)

Common bacteria on verge of becoming antibiotic-resistant superbugs
Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis. (2015-03-25)

UC San Diego scientists receive $9.5 million NIH grant to combat antibiotic resistance
Researchers at University of California, San Diego School of Medicine have received a five-year, $9.5-million award from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health to establish an interdisciplinary center to define the systems biology of antibiotic resistance. The program will be led by Bernhard Palsson, Ph.D., Distinguished Professor of Bioengineering and Pediatrics, and Victor Nizet, M.D., professor of pediatrics and pharmacy. (2016-04-12)

First study to confirm that antibiotic choice significantly impacts long-term patient outcomes for acute infections
An investigational new antibiotic, gemifloxacin mesylate (Factive®), produced significant long-term clinical and health economic outcomes compared to clarithromycin in acute exacerbations of chronic bronchitis (AECB), according to a study involving McMaster University researchers and presented today at the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy. (2000-09-13)

U-M researchers discover a way to strengthen proteins
Proteins, which perform such vital roles in our bodies as building and maintaining tissues and regulating cellular processes, are a finicky lot. In order to work properly, they must be folded just so, yet many proteins readily collapse into useless tangles when exposed to temperatures just a few degrees above normal body temperature. (2009-12-10)

Customized treatments for sepsis lower treatment time and reduce length of ICU stays
Using a blood test and a decision algorithm, rather than standard hospital protocols, to determine the appropriate length of antibiotic therapy in patients with severe sepsis or septic shock can reduce duration of treatments, shorten ICU stays, and lower hospital costs -- all without adverse effects on patients, according to new research. (2008-02-29)

Second most common infection in the US proving harder to treat with current antibiotics
Certain types of bacteria responsible for causing urinary tract infections, the second-most-common infection in the US, are becoming more difficult to treat with current antibiotics, according to new research from Extending the Cure (ETC), a project of the Center for Disease Dynamics, Economics & Policy. ETC released the research via its online ResistanceMap, an online tool created to track changes in antibiotic drug use and resistance, which features analysis using ETC's Drug Resistance Index. (2012-11-13)

Novel method for increasing antibiotic yields
A novel way of increasing the amounts of antibiotics produced by bacteria has been discovered that could markedly improve the yields of these important compounds in commercial production. It could also be valuable in helping to discover new compounds. With the ever-growing threat from antibiotic resistance, these tools will be very useful in ensuring that we have enough of these useful compounds in the future. (2011-09-05)

Abnormal growth of bacterial cells could be linked to anti-microbial resistance
Scientists from the University of Surrey have identified mutations in a gene in an Escherichia coli (E.coli) model that could help explain a form of anti-microbial resistance (AMR) known as 'persistence'. (2020-02-27)

The hidden hazards of antibiotic resistance genes in air
People are often notified about poor air quality by weather apps, and this happens frequently in urban areas, where levels of outdoor pollution containing particulates and soot are high. But now scientists are reporting in ACS' Environmental Science & Technology that there is another type of air contaminant that they say isn't receiving enough attention: antibiotic-resistance genes. (2018-07-25)

Coupling antibiotics with stem cells to fight off bone infections
Researchers from Kanazawa University investigated the effects of adipose-derived stem cells (ADSCs) loaded with the antibiotic ciprofloxacin on osteomyelitis caused by implants. By administering ADSC-loaded ciprofloxacin to the site of bone infection in rats, the researchers found a significant improvement of the infection, as shown by reduced soft tissue swelling, abscess formation, and bone degradation. These findings suggest a potential new therapy for implant-related bone infections that have traditionally been difficult to treat with antibiotics. (2020-10-01)

Research establishes antibiotic potential for cannabis molecule
The main nonpsychoactive component of cannabis has been shown to kill the bacteria responsible for gonorrhoea, meningitis and legionnaires disease, which could lead to the first new class of antibiotics for resistant bacteria in 60 years. (2021-01-19)

How one strain of MRSA becomes resistant to last-line antibiotic
Researchers have uncovered what makes one particular strain of methicillin-resistant Staphylococcus aureus (MRSA) so proficient at picking up resistance genes, such as the one that makes it resistant to vancomycin, the last line of defense for hospital-acquired infections. They report their findings in mBio, the online open-access journal of the American Society for Microbiology, on Tuesday May 22. (2012-05-22)

Battling with bugs to prevent antibiotic resistance
New scientific research published today in the journal PLoS Biology shows that bacteria can evolve resistance more quickly when stronger antibiotics are used. (2013-04-23)

Antibiotics and biocidal cleaners may spread multidrug resistance in MRSA
Antibiotic use on people or pets, and use of biocidal cleaning products such as bleach, are associated with multidrug resistance in methicillin-resistant Staphylococcus aureus (MRSA) in the home. This contamination of the home environment may contribute to reinfection of both humans and animals with MRSA, and to subsequent failure of treatment. The research is published Sept. 22 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. (2017-09-22)

Wayne State receives $1.9 million NIH award to aid in treatment of life-threatening infections
Infections caused by vancomycin-resistant Enterococcus faecium (VREfm) bacteria can often be serious and life threatening. These drug-resistant bacterial pathogens are one of the most problematic in the hospital setting, especially in immune system deficient patients, and constitute an emerging local and global health crisis. Wayne State University recently received a five-year, $1.9 million grant from the the National Institutes of Health to further explore treatment of these problematic bacteria in the hospital setting. (2016-01-15)

Caution, tasteless! Viruses and antimicrobially resistant bacteria in foods
Salmonella in eggs, noroviruses in frozen berries, hepatitis E viruses in domestic pigs and wild boar and resistant bacteria in meat: pathogenic microorganisms are one of the most common causes of foodborne illnesses. Every year, they cause more than 100,000 cases of disease in Germany -- some of them fatal. (2018-11-08)

Whole genome sequencing method may speed personalized treatment of drug-resistant infections
Researchers at Johns Hopkins Medicine say they have added to evidence that rapid resistance gene sequencing technology can accurately speed the identification of specific antibiotic-resistant bacteria strains that sicken and kill some patients. A report on a proof of concept study, published in the January 2019 issue of Antimicrobial Agents and Chemotherapy, suggests the technology has the potential to hasten the 'personalized' choice of antibiotics critically ill patients need. (2019-01-17)

For children with respiratory infections, antibiotics with narrower targets are better
When doctors prescribe antibiotics for children with common respiratory infections, a more selective approach is better. A study of 30,000 children with earaches, strep throat and other common infections found that narrow-spectrum antibiotics, which act against a smaller range of bacteria, had fewer adverse effects than broad-spectrum antibiotics, which target a broader variety of bacteria. For both practical and clinical outcomes, narrow-spectrum antibiotics performed equally well or better than broad-spectrum ones, with fewer disruptions to family routines. (2018-01-30)

Study examines bacterial susceptibility to antibiotics used to treat gonorrhea
Although gonorrhea susceptibility to the antibiotic cefixime has been improving in recent years, suggesting a halt of a drift towards antibiotic resistance, data for 2014 indicates a worsening of susceptibility, according to a study in the Nov. 3 issue of JAMA. (2015-11-03)

Bioinspired agent kills drug-resistant bacteria
Microbial resistance to antibiotics and biocides is increasing, and our ability to effectively treat bacterial infections and contamination is under threat. Researchers have developed an antimicrobial treatment that can rapidly kill drug-resistant bacteria. These iodo-thiocyanate complexes caused rapid bacterial death in the tested strains, which included an antibiotic-resistant strain. They could kill both free-floating bacteria and those in biofilms, suggesting that they could be used for decontamination in a variety of situations. (2017-05-02)

Rationale and prospects of targeting bacterial 2-component systems
Antimicrobial resistance is a major societal problem as there are resistant bacteria to any antibiotic available, and they spread across countries and continents. (2017-04-26)

Pneumococcal vaccine significantly reduces disease in South African children
In a clinical trial conducted in nearly 40,000 young children in Soweto, South Africa, a pneumococcal conjugate vaccine aimed at nine strains of disease reduced the incidence of pneumonia, invasive pneumococcal disease, and disease caused by antibiotic-resistant strains, in both HIV-infected and non-HIV-infected children. (2003-10-01)

Antibiotic side effects in kids lead to nearly 70,000 ER visits in the US each year
The use of antibiotics drives the development of antibiotic resistance, a major threat to public health worldwide. But these drugs also carry the risk of harm to individual patients, including children. According to a new analysis published in the Journal of the Pediatric Infectious Diseases Society, antibiotics led to nearly 70,000 estimated emergency room visits in the US each year from 2011-2015 for allergic reactions and other side effects in children. (2018-08-23)

Anthrax enzyme images reveal secrets of antibiotic resistance, suggest new drug design
Computer-generated images of a crucial anthrax bacterium enzyme are helping to solve the mystery of how slight mutations in the shape of this protein can make it resistant to the antibiotics called sulfa drugs. These findings, by scientists at St. Jude Children's Research Hospital, appear in the September issue of Structure. (2004-09-23)

Combination therapy promising against blindness-causing bacterial keratitis
Multidrug-resistant bacterial infections of the cornea are a leading cause of blindness and cannot be effectively managed with current ophthalmic antibiotics. A team of investigators has now devised a combination therapy that largely circumvents resistance, and quickly and effectively eradicated bacterial keratitis in 70 percent of animal models treated. (2018-11-12)

Efforts needed to stop the spread of carbapenem-resistant Acinetobacter baumannii
ECDC's latest risk assessment highlights the need of increased efforts to face this significant threat to patients and healthcare systems in all EU/EEA countries and outlines options to reduce risks through clinical management, prevention of transmission in hospitals and other health-care settings, prevention of cross-border transmission, and improvement of preparedness of EU/EEA countries. (2016-12-14)

Yale scientist honored with Keio University Medical Science Prize
Thomas A. Steitz, Sterling Professor of Molecular Biophysics and Biochemistry at Yale, received the 11th Keio Medical Science Prize in a ceremony and commemorative symposium at Keio University in Tokyo, Japan, for research that produced the first X-ray crystallographic imaging of the large ribosomal subunit. The award, in recognition of outstanding achievements in medical or life sciences, is the only prize of its kind awarded by a Japanese University. (2006-11-22)

Antibiotics weaken flu defenses in the lung
Antibiotics can leave the lung vulnerable to flu viruses, leading to significantly worse infections and symptoms, finds a new study in mice led by the Francis Crick Institute. The research, published in Cell Reports, discovered that signals from gut bacteria help to maintain a first line of defense in the lining of the lung. When mice with healthy gut bacteria were infected with the flu, around 80% of them survived. However, only a third survived if they were given antibiotics before being infected. (2019-07-02)

NIAID-sponsored study to assess shorter-duration antibiotics in children
Physicians at five US medical centers are planning to enroll up to 400 children in a clinical trial to evaluate whether a shorter course of antibiotics -- five days instead of 10 -- is effective at treating community-acquired pneumonia in children who show improvement after the first few days of taking antibiotics. The National Institute of Allergy and Infectious Diseases, part of NIH, is sponsoring the clinical trial. (2016-11-28)

How to fight drug-resistant bacteria
This year, the US reported for the first time that a patient had been infected by bacteria resistant to colistin, an antibiotic of last resort. The announcement followed several years of warnings that current antibiotics aren't diverse enough to fight pathogens as drug resistance spreads. The cover story of Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, sums up how researchers are trying to stay ahead of the bugs. (2016-09-07)

A faster and cheaper way to produce new antibiotics
A novel way of synthesizing a promising new antibiotic has been identified by scientists at the University of Bristol. By expressing the genes involved in the production of pleuromutilin in a different type of fungus, the researchers were able to increase production by more than 2,000 per cent. (2016-05-04)

Vacuum dust: A previously unknown disease vector
The aerosolized dust created by vacuum cleaners contains bacteria and mold that (2013-09-30)

Patient expectations of acute bronchitis not consistent with the best evidence
New research from the University of Georgia exposes a large discrepancy in the length of time patients expect an acute cough illness, also called acute bronchitis, to last and the reality of the illness. This mismatch may be a factor in the over-prescription of antibiotics. (2013-01-14)

Drug developed at Pitt proves effective against antibiotic-resistant 'superbugs'
A treatment pioneered at the University of Pittsburgh Center for Vaccine Research is far more effective than traditional antibiotics at inhibiting the growth of drug-resistant bacteria, including so-called 'superbugs' resistant to almost all existing antibiotics, which plague hospitals and nursing homes. The findings provide a needed boost to the field of antibiotic development, which has been limited in the last four decades and outpaced by the rise of drug-resistant bacterial strains. (2014-12-10)

Technology leads to better treatment for Staphylococcus aureus sepsis
A new testing and treatment approach led to shorter hospital stays for patients with Staphylococcus aureus bloodstream infections. Study results were presented at the ASM Microbe 2017 conference in New Orleans, LA, on June 3, 2017. (2017-06-03)

First study to link antibiotic resistance with exposure to the disinfectant chlorhexidine
Klebsiella pneumoniae bacteria exposed to chlorhexidine-containing disinfectants can become resistant to colistin, a last resort antibiotic often used against multidrug resistant pathogens. This is the first study to link exposure to chlorhexidine with resistance to colistin in this clinically important pathogen. (2016-10-31)

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