Antibiotic Current Events

Antibiotic Current Events, Antibiotic News Articles.
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'Tolerant' bacteria drive resistance to antibiotics
Disease-causing bacteria that become resistant most quickly to the antibiotic ampicillin do so by acquiring mutations that allow them to tolerate the antibiotic first, a new study reveals. (2017-02-09)

Recent research uncovers surprises about antibiotic resistance
It's thought that antibiotic resistance is associated with a fitness cost, meaning that bacteria that develop antibiotic resistance must sacrifice something in order to do so. Because of this, proper use of antibiotics should result in susceptible strains eventually replacing resistant ones. (2016-06-07)

How antibiotic use in animals is contributing to antibiotic resistance
The overuse of veterinary antibiotics in animal production and the subsequent land applications of manure contribute to increased antibiotic resistance in soil. (2017-11-20)

High doses of antibiotics may have the potential to promote increased cross-resistance
In the advanced online edition of Molecular Biology and Evolution, Oz, et. al., utilized an experimental evolution approach to evolve 88 different E. coli populations against 22 antibiotics, under 'strong' and 'mild' selection conditions. (2014-06-24)

Time to drop 'complete the course' message for antibiotics
The deeply embedded message that patients should 'complete the course' of antibiotics to avoid antibiotic resistance is not backed by evidence and should be dropped, argue experts in The BMJ today. (2017-07-26)

Guidelines for treatment of Community Acquired Pneumonia need to be made clearer
University of Alberta researchers have found that an antibiotic therapy prescribed to patients with suspected Community-Acquired Pneumonia (CAP) was not indicated according to Canadian guidelines in 50 percent of the cases where it was received. (2003-04-14)

New way to improve antibiotic production
New research findings could reduce production times and therefore costs for antibiotic producers. (2013-06-17)

Drugs used to overcome cancer may also combat antibiotic resistance: McMaster researchers
The pharmaceutical sector has made a big investment in targeting kinases proteins, so there are a lot of compounds and drugs out there that, although they were designed to overcome cancer, they can in fact be looked at with fresh eyes and maybe repurposed to address the problem of antibiotic resistance. (2011-12-22)

Antibiotic prescribing in local communities is linked to localised resistance
In this week's BMJ a team of researchers from Wales show for the first time that antibiotic prescribing within geographic communities can lead to localised antibiotic resistance. (1999-11-04)

World first study shows that some microorganisms can bend the rules of evolution
The dominant thinking in evolution focuses on inheritance between parent and offspring - or 'vertical gene transfer (VGT)'. But now scientists are paying more attention to 'horizontal gene transfer (HGT)': the transmission of DNA other than from parent to offspring, as this transfer can tell us about the evolution of a number of other organisms such as bacteria. It can also help us to better understand antibiotic resistance. (2020-10-13)

Scientists must reduce antibiotic use in experiments
Scientists should reduce antibiotic use in lab experiments -- according to a researcher at the University of East Anglia. Microbiology, molecular biology and genetic research such as the Human Genome Project use antibiotics in experiments. But it all adds to the global problem of antibiotic resistance according to Dr. Laura Bowater, from UEA's Norwich Medical School. (2015-03-20)

Study examines urinary tract infections and antibiotic use in nursing homes
In a Journal of the American Geriatrics Society study of nursing homes in the tropics, one in five residents had received antibiotics within the last 30 days. Also, urinary tract infection (UTI) accounted for 40 percent of all infections treated with antibiotics within the last 30 days. (2018-01-10)

Journal publishes special section on antibiotics in agroecosystems
A special collection presents the state of science for evaluating antibiotic resistance in agroecosystems. (2016-03-03)

Antibiotic resistance linked to corruption: ANU media release
Researchers have linked antibiotic resistance with poor governance and corruption around the world. (2015-03-18)

EU report: More evidence on link between antibiotic use and antibiotic resistance
The European Food Safety Authority, the European Medicines Agency and the European Centre for Disease Prevention and Control are concerned about the impact of use of antibiotics on the increase in antibiotic-resistant bacteria. The report presents new data on antibiotic consumption and antibiotic resistance and reflects improved surveillance across Europe. (2017-07-27)

University of Manchester technology set to lead fight against anti-microbial resistance
Professor Douglas Kell and colleagues have developed novel technology that identifies the most effective antibiotic to kill organisms in urinary tract infections. (2019-04-04)

Study finds some reductions in community antibiotic resistant infections and dispensing
A study by academics at the University of Bristol has found reductions in overall and individual antibiotic dispensing between 2013 and 2016 after evaluating, for the first time, national primary care prescribing policy on community antibiotic resistant infection. (2020-05-19)

Multi-species bacterial communities bounce back from environmental disturbances
Perturbations in the environment are common, and communities consisting of several species seem to find their way around the crisis. Species immigration is beneficial for community recovery. (2020-08-10)

Antibiotics have long-term impacts on gut flora
Short courses of antibiotics can leave normal gut bacteria harboring antibiotic resistance genes for up to two years after treatment, say scientists writing in the latest issue of Microbiology, published on Nov. 3. The researchers believe that this reservoir increases the chances of resistance genes being surrendered to pathogenic bacteria, aiding their survival and suggesting that the long-term effects of antibiotic therapy are more significant than previously thought. (2010-11-01)

Prescribing of antibiotics to children still at a level to cause drug resistance, warn experts
Regular prescribing of antibiotics to children in the community is sufficient to sustain a high level of antibiotic resistance in the population, warn experts in a study published online today. UK general practitioners are strongly encouraged to reduce antibiotic prescribing to minimize the risk of drug resistance, yet prescribing antibiotics to children remains common practice, write David Mant and colleagues at the University of Oxford. (2007-07-26)

Report examines use of antibiotics in agriculture
Antibiotics have been used against infectious diseases with great success and have been a part of agriculture for many years, but scientists have long recognized a down side. The concentrated and widespread use of antibiotic agents has resulted in the emergence of drug-resistant organisms, some of which can now survive most commercially available antibiotics. A new report from the American Academy of Microbiology (AAM), (2002-10-24)

Antibiotic resistance markers in GM plants not a risk to human health
Antibiotic-resistance markers in genetically modified (GM) plants do not pose a substantial risk to human health, concludes a review article published in the October issue of The Lancet Infectious Diseases. (2005-09-27)

Controlling antibiotics and antibiotic resistance in hospitals
In a study of nearly 450 hospitals nationwide, researchers from Indiana University School of Medicine, Regenstrief Institute, Inc. and Roudebush VAMC report that hospitals that follow national guidelines on controlling antibiotic use have lower rates of antibiotic resistance. (2006-10-09)

Probiotics may prevent antibiotic associated diarrhoea
Probiotics (microbes that protect their host and can prevent disease) can prevent diarrhoea associated with the use of antibiotics, finds a study in this week's BMJ. (2002-06-06)

Daily dose of antibiotics helps bacteria develop multi-drug tolerance
Antibiotics do not easily eradicate the gut bacteria Escherichia coli, as some bacteria survive treatment in a dormant state. Once treatment is stopped, these dormant cells can become active again and recolonize the body. Researchers from KU Leuven, Belgium, have shown that the more frequently bacteria receive antibiotics, the more of them survive. What is more, these survivors have evolved into bacteria with multi-drug tolerance. (2016-03-07)

Antimicrobial resistance in soil and the potential impact on the food chain
New research at the University of Southampton is to investigate if large amounts of antibiotic resistant bacteria are present in agricultural soil which may spread into the food chain. (2016-05-23)

Antibiotic allergy reporting may lead to resistance, higher costs, decreased safety
Antibiotics are among the most commonly prescribed medications, but in determining the most appropriate prescription for a patient, doctors and pharmacists often rely on inaccurate records of the patient's antibiotic allergies. Many records are incomplete, unclear or incorrect. (2020-07-14)

Antibiotic reduction campaigns do not necessarily reduce resistance
Antibiotic use -- and misuse -- is the main driver for selection of antibiotic resistant bacteria. This has led many countries to implement interventions designed to reduce overall antibiotic consumption. Now, using methicillin resistant Staphylococcus aureus as an example, Laura Temime of the Conservatoire National des Arts et Metiers, Paris, and collaborators warn that simply reducing antibiotics consumption does not necessarily reduce resistance. The research is published online ahead of print in Antimicrobial Agents and Chemotherapy. (2013-07-29)

Antibiotic Prophylaxis Could Help Prevent Respiratory Infections in the Critically Ill
Some respiratory tract infections developed by patients in intensive care could perhaps be prevented by the use of antibiotic prophylaxis, suggest researchers from the Mario Negri Institute for Pharmacological Research in Italy. (1998-04-24)

Why do some infections persist? Blame bacterial socialism, says new study
New research to be published in Scientific Reports uses time lapse microscopy to show that bacteria use a hedging strategy to trade off varying degrees of antibiotic resistance even when they are not under threat. This new insight could explain why some infections persist in spite of antibiotic treatment and suggests that a different dosing strategy that would wait out trading off strategy could be effective. (2016-01-13)

Reduced antibiotic prescribing is associated with increased hospital admissions
A study published in the Journal of the Royal Society of Medicine indicates that efforts to reduce antibiotic resistance in the USA led to a decrease in the prescribing of antibiotics by doctors yet an increase in hospitalizations for respiratory infections like pneumonia. In analyses of more than 15.5 million hospitalizations and 5.5 million outpatient visits per year over 8 years, this trend was particularly strong between 1998 and 2002. (2006-06-21)

Antibiotic resistance genes are essentially everywhere
The largest metagenomic search for antibiotic resistance genes in the DNA sequences of microbial communities from around the globe has found that bacteria carrying those vexing genes turn up everywhere in nature that scientists look for them. The findings reported in the Cell Press journal Current Biology on May 8 add to evidence showing just how common and abundant those resistance genes really are in natural environments. (2014-05-08)

Outpatients, hospital patients face growing, but different problems with antibiotic resistance
A new study concludes that problems with antibiotic resistance faced by outpatients may be as bad as those in hospitalized patients, and that more studies of outpatients are needed -- both to protect their health and to avoid inappropriate or unnecessary drug use. (2013-04-18)

Widespread, occasional use of antibiotics in US linked with resistance
The increasing prevalence of antibiotic resistance in the U.S. appears more closely linked with their occasional use by many people than by their repeated use among smaller numbers of people, according to a large new study from Harvard T.H. Chan School of Public Health. (2018-12-18)

Supermarket produce harbors antibiotic-resistance genes
Researchers from the Julius Kühn Institut, Germany have found that produce is a reservoir for transferable antibiotic resistance genes that often escape traditional molecular detection methods. These antibiotic resistance genes might escape cultivation-independent detection, but could still be transferred to human pathogens or commensals. The results, which highlight the importance of the rare microbiome of produce as a source of antibiotic resistance genes, are published November 6 in the open-access journal, mBio. (2018-11-06)

Hard-to-detect antibiotic resistance an underestimated clinical problem
When antibiotics are used to treat bacteria susceptible to them, the treatment usually works. Nevertheless, the antibiotic chosen is sometimes ineffective. One of the reasons for this is heteroresistance, a phenomenon explored in depth by Uppsala and Emory University researchers in a new study. (2019-02-11)

Antibiotic resistance can be caused by small amounts of antibiotics
Antibiotic-resistant bacteria are a global and growing problem in health care. To be able to prevent further development of resistance developing, it is important to understand where and how antibiotic resistance in bacteria arises. New research from Uppsala University shows that low concentrations of antibiotics, too, can cause high antibiotic resistance to develop in bacteria. (2018-04-23)

New insight into antibiotic resistance strengthens call for increased focus on research
Scientists at the University of Birmingham have identified a new mechanism of antibiotic resistance in bacterial cells which could help us in understanding, and developing solutions to, the growing problem of antibiotic resistance. (2015-03-02)

Investigating antibiotic use in acute care patients
Pigs could be the key to understanding how antibiotic resistant bacteria persist in intensive care units in hospitals. Using pigs as a model, scientists from the NSW Department of Primary Industries in Sydney have examined how E. coli bacteria -- a common cause of diarrhea in pigs and humans -- respond to treatment by antibiotics. (2007-07-31)

Developing the tools to find new generation antibiotics
Scientists at the University of York have taken an important step in the search to find new antibiotics that are effective against resistant bacteria. Research led by Professor Maggie Smith in the Department of Biology at York will provide new tools for creating stable genetically engineered strains which could lead to improvements to existing antibiotics and the development of new ones. (2015-10-15)

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