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Antidepressant Current Events, Antidepressant News Articles.
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Antidepressants associated with increased risk for suicide attempts, decreased risk for death
Suicidal individuals taking antidepressant medications appear to have an increased risk of additional suicide attempts, but a reduced risk of dying from suicide or any other cause, according to a large Finnish study reported in the December issue of Archives of General Psychiatry, one of the JAMA/Archives journals. (2006-12-04)

Antidepressants may increase risk of abnormal bleeding
New users of selective serotonin reuptake inhibitors (SSRIs, a type of antidepressant) have an increased risk of being admitted to the hospital for abnormal bleeding, according to an article in the November 22 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals. (2004-11-22)

The Lancet: Mindfulness-based therapy could offer an alternative to antidepressants for preventing depression relapse
Mindfulness-based cognitive therapy could provide an alternative non-drug treatment for people who do not wish to continue long-term antidepressant treatment, suggests new research published in The Lancet. (2015-04-20)

PTSD, major depressive episode appears to increase risk of preterm birth
Diagnoses of both post-traumatic stress disorder and a major depressive episode appear to be associated with a sizable increase in risk for preterm birth that seems to be independent of antidepressant and benzodiazepine medication use. (2014-06-11)

UCLA leading a $13.9M effort to treat older adults with persistent depression
UCLA and four other institutions have been awarded a $13.9 million grant to evaluate treatment strategies for older adults with depression who have not responded to medications. (2016-10-04)

Depressed stroke patients often not treated for depression
Despite a high rate of depression, few stroke survivors take antidepressants, according to a study in Stroke: Journal of the American Heart Association. (2006-09-28)

Antidepressants can reduce the empathic empathy
Depression is a disorder that often comes along with strong impairments of social functioning. Until recently, researchers assumed that acute episodes of depression also impair empathy, an essential skill for successful social interactions and understanding others. Novel insights of an interdisciplinary from the University of Vienna and the Medical University of Vienna show that antidepressant treatment can lead to impaired empathy regarding perception of pain, and not just the state of depression itself. (2019-06-18)

Mindfulness-based therapy rather than antidepressants to prevent depression relapse?
Researchers from Plymouth University Peninsula Schools of Medicine and Dentistry are part of a team led by the University of Oxford whose new research suggests that mindfulness-based therapy could be an alternative to antidepressants to prevent depression relapse. (2015-04-22)

Antidepressants may be associated with modestly increased risk of suicidality in children
An analysis of data from 24 clinical trials suggests that antidepressant medications may be linked to a modest increase in the risk of suicidal thoughts and behaviors in children, according to an article in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals. (2006-03-06)

Are antidepressants more effective than usually assumed?
Many have recently questioned the efficacy of the most common antidepressant medications, the selective serotonin reuptake inhibitors. The conclusion that these drugs are ineffective is however partly based on a misinterpretation of the outcome of the clinical trials once conducted to demonstrate their efficacy. This was the finding of a study conducted by researchers at the Sahlgrenska Academy. (2015-05-27)

Low strength brain stimulation may be effective for depression
Brain stimulation treatments, like electroconvulsive therapy and transcranial magnetic stimulation, are often effective for the treatment of depression. Like antidepressant medications, however, they typically have a delayed onset. For example, a patient may receive several weeks of regular electroconvulsive therapy treatments before a full response is achieved. (2014-07-22)

Group activities reduced depressive symptoms among older people with dementia
Both a high-intensity functional exercise programme and a non-exercise group activity, conducted among older care facility residents with dementia, reduced high levels of depressive symptoms. However, exercise had no superior effect on depression, according to a dissertation from UmeƄ University. (2016-05-03)

Medication or psychotherapy effective in treating depressed patients when the other is not
Switching from an antidepressant medication to psychotherapy or vice versa may improve symptoms in chronically depressed patients who prove unresponsive to their initial treatment, according to an article in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals. (2005-05-02)

Antidepressant may help people stop smoking when used with nicotine patch
When used with a transdermal nicotine patch, nortriptyline--an antidepressant medication--may aid in smoking cessation, according to an article in the November 8 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals. (2004-11-08)

New type of antidepressant found to act quickly in mice
The compound CGP3466B, already proven nontoxic for people, may effectively and rapidly treat depression, according to results of a study in mice. (2016-01-12)

Researchers uncover new insights into developing rapid-acting antidepressant for treatment-resistant depression
UT Southwestern Medical Center researchers have generated fresh insights that could aid in the development of rapid-acting antidepressants for treatment-resistant depression. (2014-06-12)

Antidepressants during pregnancy linked to preterm birth
Antidepressant medications taken by pregnant women are associated with increased rates of preterm birth. This finding reinforces the notion that antidepressants should not be used by pregnant women in the absence of a clear need that cannot be met through alternative approaches, say researchers from Brigham and Women's Hospital, Vanderbilt University, MetroWest Medical Center, and Tufts Medical Center. (2014-03-27)

Exposure/ritual prevention therapy boosts antidepressant treatment of OCD
Scientists have demonstrated that a form of behavioral therapy can augment antidepressant treatment of obsessive compulsive disorder (OCD) better than an antipsychotic. The researchers recommend that this specific form of cognitive behavior therapy -- exposure and ritual prevention -- be offered to OCD patients who don't respond adequately to treatment with an antidepressant alone, which is often the case. Current guidelines favor augmentation with antipsychotics. (2013-09-12)

Popular antidepressant blocks the beneficial effects of tamoxifen in breast cancer
Women with breast cancer who take the antidepressant paroxetine at the same time as tamoxifen are at an increased risk of death, concludes a study published on bmj.com today. (2010-02-08)

Antidepressants linked to tooth implant failure, new study finds
Antidepressants, commonly used to treat anxiety, pain and other disorders, quadruple the risk of dental implant failure, according to a new pilot study by University at Buffalo researchers. (2016-03-08)

New antidepressants increase risks for elderly
Older people taking new generation antidepressants are at more risk of dying or suffering from a range of serious health conditions including stroke, falls, fractures and epilepsy, a study involving researchers at the University of Nottingham has found. (2011-08-02)

Both antidepressant therapy and counseling may help smokers achieve short-term abstinence
A study to determine whether counseling increases the efficacy of antidepressants in smoking cessation programs found that such combination therapy did not add benefit to antidepressant therapy. It also found that counseling increased short-term abstinence rates when it was added to medical management, but neither counseling nor antidepressant therapy produced long-term sustained abstinence. Counseling produced higher 7-day abstinence rates than medical management alone, but this improvement was not sustained over the course of the study. (2003-02-20)

Researchers identify potentially revolutionary antidepressant compound
Ketamine can treat depression rapidly. But it has major side effects, including hallucinations. Now, researchers have identified a metabolite of ketamine that quickly reverses depression in mice, without ketamine's side effects. (2016-05-04)

New antidepressant acts very rapidly and is long lasting
A first-of-its-kind antidepressant drug discovered by a Northwestern University professor and now tested on adults who have failed other antidepressant therapies has been shown to alleviate symptoms within hours, have good safety and produce positive effects that last for about seven days from a single dose. The novel therapeutic targets brain receptors responsible for learning and memory -- a very different approach from existing antidepressants. The new drug could be helpful in treating other neurological conditions. (2012-12-06)

Study supports the long-term benefits of transcranial magnetic stimulation for depression
In a study to determine the durability and long-term effects of transcranial magnetic stimulation, psychiatric researchers at Rush University Medical Center have found the non-invasive, non-drug therapy to be an effective, long-term treatment for major depression. Results of the study were published in the October 2010 issue of Brain Stimulation, a journal published by Elsevier. (2010-10-11)

The neural basis of the depressive self
In the general population, depression is still frequently associated with bad lifestyle, impairment of volition and (2010-08-31)

Binge eating and smoking linked to bullying and sexual abuse
People who ever suffered bullying or sexual abuse have a lower quality of life similar to those living with chronic conditions like heart disease, diabetes, depression or severe anxiety, a new study from the University of Adelaide has found. (2019-01-11)

Longtime antidepressant could slow Parkinson's
Michigan State University scientists now have early proof that an antidepressant drug that's been around for more than 50 years could slow the progression of Parkinson's. (2017-09-05)

Telephone therapy for depression? Study says yes
A trial shows professional counseling for depression may be just as effective over the phone as traditional face-to-face consultations. (2010-05-10)

Antidepressant use during pregnancy may lead to childhood obesity and diabetes
Women who take antidepressants during pregnancy may be unknowingly predisposing their infants to type 2 diabetes and obesity later in life, according to new (animal model) research from McMaster University, Hamilton, Ontario, Canada. (2014-06-21)

Common antidepressant increased coronary atherosclerosis in animal model
A commonly prescribed antidepressant caused up to a six-fold increase in atherosclerosis plaque in the coronary arteries of non-human primates, according to a study by researchers at Wake Forest Baptist Medical Center. Coronary artery atherosclerosis is the primary cause of heart attacks. (2015-04-06)

Getting dirty may lift your mood
Treatment of mice with a (2007-04-01)

New mouse model of depression/anxiety enhances understanding of antidepressant drugs
A recent study finds that the antidepressant effects of drugs like Prozac involve both neurogenesis-dependent and -independent mechanisms, a finding that may lead to development of better treatments for depression and anxiety. The research, published by Cell Press in the May 28 issue of the journal Neuron, utilizes a new experimental mouse model of depression/anxiety that is the first to permit simultaneous examination of multiple effects of antidepressant treatment in the same animal. (2009-05-27)

Antidepressant drug trials turn away most of the depressed population
Studies establishing the effectiveness of antidepressants are based on highly selective samples of depressed patients. New research by Brown University psychiatrists found as many as 85 percent of depressed patients treated in an outpatient setting would be excluded from the typical study to determine whether an antidepressant works. (2002-02-28)

Studies suggest inflammatory cytokines are associated with depression and psychosis, and that anti-cytokine treatment can reduce depression symptoms
Studies presented at this year's International Early Psychosis Association meeting in Milan, Italy, (Oct. 20-22) suggest that increased levels of inflammatory cytokines are associated with increased rates of depression and psychosis, and that treatment to reduce cytokine levels can reduce symptoms of depression. (2016-10-20)

Study shows new strategy for developing antidepressants
Researchers may be able to develop an antidepressant which takes effect almost immediately by directly targeting novel molecules in the brain instead of taking a less direct route, which can lead to longer times for medication to take effect, according to a new study presented at the American College of Neuropsychopharmacology Annual Meeting. (2007-12-08)

Behavior therapy plus medication may help teens with depression and substance use disorders
The antidepressant fluoxetine combined with cognitive behavioral therapy appears as effective for treating depression among teens who also have substance use disorders as among those without substance abuse problems, according to a report in the November issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. (2007-11-05)

Small study shows SAMe may improve treatment of depression
Massachusetts General Hospital researchers have found that adding the nutritional supplement SAMe to a standard antidepressant may be helpful to patients who have not responded to single-drug treatment for clinical depression. (2004-11-30)

Antidepressant warnings associated with decreased prescription rates among Tennessee children
Regulatory warnings regarding the risk of suicidal thoughts and behaviors appear to be associated with reductions in the number of antidepressant medication prescriptions among children and adolescents covered by Tennessee's expanded Medicaid program, according to a report in the July issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA and Archives journals. (2007-07-02)

Brain scan before antidepressant therapy may predict response
A functional MRI brain scan may help predict which patients will respond positively to antidepressant therapy, according to a new study published in the journal Brain. (2017-01-24)

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