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American Thoracic Society Journal news tips for April 2004 (first issue)
Newsworthy studies show that: patients with chronic obstructive pulmonary disease who were current high-dose users of inhaled corticosteroids had an increased risk of fractures; over 6 years, researchers found that greater use of the analgesic acetaminophen was associated with an increased new diagnosis of adult-onset asthma in women; and investigators found that exposure to tiny particulate matter and ozone was associated with cystic fibrosis patients having two or more serious pulmonary exacerbations. (2004-03-26)

NSAIDs increase cardiovascular, bleeding risk in Korean heart attack patients
Use of NSAIDs to treat first-time heart attack patients significantly increased the risk for cardiovascular and bleeding events post-heart attack in a nationwide Korean study, published today in the Journal of the American College of Cardiology. (2020-07-27)

ACE-Inhibitors Score High In Reducing Heart Attack Deaths
DALLAS, June 9 -- A type of drug that lowers high blood pressure improves a person's odds of surviving after a heart attack, say researchers reporting on a study of nearly 100,000 heart attack patients that appears in today's Circulation: Journal of the American Heart Association. (1998-06-08)

New guidelines offer power to prevent stroke
Healthy habits and appropriate treatments help prevent stroke, according to graded, evidenced-based recommendations issued today by the American Heart Association and it's division, the American Stroke Association. (2006-05-05)

NYU Langone Medical Center cardiologists present at ACC 60th Annual Scientific Session
Cardiologists from the Cardiac & Vascular Institute at NYU Langone Medical Center presented new research findings at the American College of Cardiology 60th Annual Scientific Session held April 2-5, 2011 in New Orleans, La. (2011-04-05)

Paracetamol remains treatment of choice, say GI experts
A clear picture of the true extent of gastrointestinal (GI) complications with over-the-counter (OTC) doses of non- steroidal anti-inflammatory drugs (NSAIDS) is not yet available, say researchers at the 'Clinical Consensus - An International Update on Paracetamol' symposium in Sydney, Australia. (1999-11-07)

Got a pain? -- Have a cup of Brazilian mint
Scientists at Newcastle University test the pain relieving properties of Hyptis crenata -- Brazilian mint. (2009-11-24)

Marked improvement in heart attack care seen in 33-hospital study
Despite huge advances in heart attack care, many patients go without proven therapies because doctors and nurses forget or neglect to prescribe them. Now, new results from a 33-hospital study show that a system of reminders and other tools greatly improves the percentage of heart attack patients receiving proven treatments. (2003-04-01)

Smoking, diabetes predict different forms of peripheral artery disease
Cigarette smoking and high cholesterol predict risk for some forms of peripheral artery disease (PAD), while diabetes predicts risk for other forms of the disease, researchers reported in a rapid access issue of Circulation: Journal of the American Heart Association. (2006-05-31)

Mayo Clinic Cardiologist Available To Discuss New Guidelines On Treatment Of Stable Angina
Expert committee sorts out proven strategies for treatment of chest pain

What: The American Heart Association, the American College of Cardiology and the American College of Physicians-American Society of Internal Medicine will release the first guidelines ever published on treating patients with chronic stable angina. This condition affects more than 10 million Americans with associated costs of tens of billions of dollars. (1999-05-27)

Arthritis drugs may help the heart
Anti-inflammatory drugs used to treat arthritis may also benefit people with heart disease by improving blood vessel flexibility and reducing inflammation, according to a small study in today's rapid track report from Circulation: Journal of the American Heart Association. (2003-01-13)

Yale researchers find environmental toxins disruptive to hearing in mammals
Yale School of Medicine researchers have new data showing chloride ions are critical to hearing in mammals, which builds on previous research showing a chemical used to keep barnacles off boats might disrupt the balance of these ions in ear cells. (2006-04-11)

Warfarin Continues To Be Underused As Stroke Preventive
Despite powerful evidence that the blood-thinning drug warfarin can prevent strokes in people with atrial fibrillation -- a type of irregular heartbeat -- the drug continues to be seriously underprescribed, according to a study by two physicians from the Massachusetts General Hospital. (1998-04-08)

Women at heart: Stop the bias
Women presenting with symptoms of heart disease are investigated less thoroughly and treated less aggressively by cardiologists across Europe. (2005-09-05)

Molecular 'magnets' could improve cancer immunotherapy
Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients, according to new research published in Cell. Scientists at the Francis Crick Institute have discovered that immune cells called Natural Killer cells accumulate in tumours and release chemicals that attract specialised dendritic cells (cDC1) - white blood cells known for triggering anti-cancer immune responses - to the tumour. (2018-02-08)

Combining NSAIDs with chemotherapy, radiation may improve cancer treatment
Certain nonsteroidal anti-inflammatory drugs may be better suited to treating cancer, in combination with standard therapies, rather than preventing it, according to new research by scientists at the University of Iowa Roy J. and Lucille A. Carver College of Medicine. (2007-05-17)

Major clinical trials on the agenda of the European Stroke Organisation Conference
Over 3,700 delegates attended ESOC 2016 today in Barcelona. Today's program included teaching courses, scientific presentations, and presentations from major clinical trials. These trials will have an immediate impact on how we care for patients with stroke. Here are some highlighted trials from the second plenary session. (2016-05-11)

Low-risk patients screened for heart disease tend to receive more preventive care and testing
Screening for coronary heart disease (CHD) among individuals at low risk of the condition is associated with increased use of medications (such as aspirin and statins) and increased additional testing, but no difference in cardiac events at 18 months, according to a report posted online today that will be published in the August 8 print issue of Archives of Internal Medicine, one of the JAMA/Archives journals. The article is part of the journal's Less Is More series. (2011-05-23)

Toxic milk
In the August 1 issue of G&D, Dr. Ronald Evans (Salk Institute) and colleagues, report on their discovery that mutations in the mouse gene encoding PPARã adversely affect lactation milk quality, and have serious health consequences for nursing pups. (2007-07-23)

Some recommended cardiovascular medications prescribed less frequently to women
In primary care, sex differences for recommended cardiovascular (CVD) prescriptions were found for patients who were at high risk or who had CVD. Women were less likely than men to receive cholesterol-lowering medicines and aspirin, yet equally likely to receive blood-pressure-lowering medications. (2020-05-20)

Chest pain center accreditation linked with better outcomes in heart attack patients
Hospitals accredited by the Society of Chest Pain Centers have been shown to perform better in the heart attack core measures established by Centers for Medicare and Medicaid Services as compared to nonaccredited hospitals, according to a national study led by an Emory University researcher. (2008-07-09)

High red blood cell folate levels linked to silenced tumor-suppressors
A study of 781 people enrolled in a colorectal cancer prevention clinical trial finds that elevated levels of red blood cell folate is associated with the deactivation of two anti-cancer genes known to be silenced in colorectal cancer. (2010-12-22)

'Inflamm-aging' causes loss of bone healing ability in the elderly
Increases in chronic inflammation -- not the passage of time -- is the main reason why injured bones do not heal as well with age. (2019-03-18)

Ticagrelor for heart attack patients -- a landmark event that should redefine patient care
New research shows that the stronger anti-clotting medication tricagrelor reduces death rates without increasing bleeding compared with the current standard treatment of clopidogrel for heart attack patients. This new analysis of the PLATO trial is reported in an article online first and in an upcoming edition of the Lancet. (2010-01-13)

New program shown to help heart attack patients get the best care
Ten Detroit-area hospitals are taking better care than ever of their heart attack patients, thanks to a simple tool kit that helps physicians, nurses and patients remember to take advantage of all the proven therapies that national guidelines recommend. The program could be a model for hospitals nationwide. (2001-03-18)

Stroke warning signs often occur hours or days before attack
Warning signs of an ischemic stroke may be evident as early as seven days before an attack and require urgent treatment to prevent serious damage to the brain, according to a study of stroke patients published in the March 8, 2005 issue of Neurology. (2005-03-07)

Annals of Internal Medicine, tip sheet, January 21, 2003
Highlights of the next issue of Annals of Internal Medicine include: Chemotherapy after breast cancer surgery not used as often as recommended; Women with heart disease are at high risk for heart attacks, but often are not taking appropriate preventive drugs; and Denver Health: an integrated, successful urban safety-net system. (2003-01-20)

Doxycycline, An Antibiotic, May Be Treatment For Osteoarthritis
Doxycycline, a common antibiotic used to treat infections and dermatological conditions, has been shown in early studies to slow the progression of--and may even protect unaffected joints from--osteoarthritis. (1997-10-29)

Plant used in Chinese medicine fights chronic pain
A plant used for centuries as a pain reliever in Chinese medicine may be just what the doctor ordered, especially when it comes to chronic pain. A key pain-relieving ingredient is a compound known as dehydrocorybulbine found in the roots of the flowering plant Corydalis, a member of the poppy family, according to researchers who report their findings in the Cell Press journal Current Biology on January 2. (2014-01-02)

Women & men differ in heart disease traits and treatment
A new study shows just how different men and women really are -- when it comes to their hearts, that is. It also helps solve several mysteries about women and heart problems, and highlights the need for better treatment of the No. 1 killer of women. (2003-11-09)

American Physiological Society's conference focuses on key gender differences in health
Cardiovascular disease and other gender-specific conditions -- such as menopause, pregnancy, depression, and obesity -- will be explored in depth at a 2-day conference sponsored by the American Physiological Society (APS). (2011-10-13)

Scientists enlist baker's yeast in a hunt for new medicines
An international team of scientists from Canada, US and Japan have come up with a new way to predict potentially useful drugs from a pool of undefined chemicals. Using this approach, they were able to more quickly identify leads that could be used to treat a range of diseases, from infections, to cancer to Alzheimer's. The finding will also help better match drugs to a disease to maximize the benefit and reduce side-effects. (2017-07-24)

Long-term anti-inflammatory drug use may increase cancer-related deaths for certain patients
Regular use of over-the-counter non-steroidal inflammatory drugs (NSAIDs) such as aspirin and ibuprofen is associated with an increased risk of dying in patients diagnosed with Type 1 endometrial cancers, according to a new population-based study led by The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James). (2016-12-19)

Hospitals that follow guidelines save lives
Heart attack death rates dropped significantly at hospitals that participated in a quality-improvement process that increased the use of evidence-based therapies, according to a new study in the Oct. 4, 2005, issue of the Journal of the American College of Cardiology. (2005-09-28)

Study reports validation and clinical application of the first point-of-care genetic test in medicine, regarding use of antiplatelet therapy following coronary interventions
A study published Online First by the Lancet reports the successful validation and clinical application of the first point-of-care genetic test in medicine. The test successfully identifies the CYP2C19*2 allele: A common genetic variant associated with increased rates of major adverse events in individuals given clopidogrel after percutaneous coronary intervention, thus avoiding complications in those patients. (2012-03-28)

Rheumatoid arthritis patients can get gout too, Mayo Clinic Study finds
Refuting a belief long held by many physicians, a Mayo Clinic study found that rheumatoid arthritis patients also can get gout. The research is among several studies Mayo Clinic is presenting at the American College of Rheumatology annual meeting in Washington. (2012-11-10)

Scripps-led study in JAMA shows new drug helps 'bridge' stent patients to cardiac surgery
New findings from a research study led by Dr. Eric J. Topol at Scripps Health reveal that the drug cangrelor has the unique properties of achieving very fast blood thinning effects when needed to protect from heart attacks, but also dissipates rapidly so patients can undergo surgery without the excessive bleeding often associated with blood thinning medications. Initial results from the BRIDGE trial will be the lead article in JAMA on Jan. 18, 2012. (2012-01-17)

Scientists analyze stroke studies from the past 50 years; Success rate of experimental drugs described as 'remarkably dismal'
After analyzing trends in acute ischemic stroke studies from the past 50 years, scientists from UCLA and the University of Pennsylvania found a (2001-05-30)

Conference to examine effects of dietary supplements in patients taking blood thinning medications
The National Heart, Lung, and Blood Institute will convene a conference this week to evaluate the risks of interactions between dietary supplements and prescription blood-thinning medications which are used by four million Americans to ward off heart attack or stroke. Experts from the National Institutes of Health and the Food and Drug Administration will join academic, patient advocacy and industry representatives to assess current knowledge, identify strategies for clinical guidelines, and determine opportunities for further research. (2005-01-10)

Personalized antiplatelet treatment improves outcome after PCI
Personalized antiplatelet treatment leads to better outcomes than standard antiplatelet treatment in patients undergoing coronary stent implantation, according to results from the MADONNA study presented at ESC Congress 2012. The findings were presented by Dr. Jolanta Siller-Matula from Medical University of Vienna. (2012-08-28)

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