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Bacterial Infections Current Events, Bacterial Infections News Articles.
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Paradigm shift: 'We need to study lumps of bacteria'
New research from the University of Copenhagen reveals that bacteria which agglutinate before entering the body are far more resistant than single-celled bacteria. This may be the cause of chronic infections. (2016-03-23)

Intestinal macrophages in liver cirrhosis produce NO, disrupt intestinal barrier function
A South African study presented today determines the importance of bacterial infections, which commonly occur in cirrhosis and can alter the natural history of the condition, possibly leading to loss of liver function and decompensation. It is now recognized that many infections in cirrhotic patients result from bacterial translocation from the intestine. (2012-04-19)

New pain target for bacterial infections
Components in the outer wall of bacteria directly activate pain sensors, triggering immediate pain and inflammatory responses. This finding by a multinational team of researchers led by Professor Karel Talavera (KU Leuven, Belgium) and Professor Félix Viana (Institute of Neuroscience, Spain) sheds new light on pain associated with bacterial infections and reveals a new target for drugs designed to treat them. (2014-02-10)

Bid to beat superbugs boosted by immune defence discovery
The fight against superbugs could be helped by the discovery of a potential therapy based on the body's natural immune defences. (2019-06-03)

Gallium: A new antibacterial agent?
New antibacterial strategies are needed because more and more bacteria are antibiotic resistant and because antibiotics are not effective at eradicating chronic bacterial infections. In a new study, using Gallium (Ga) to limit the amount of iron (Fe) to which bacteria have access protected mice from both acute and chronic Pseudomonas aeruginonsa lung infections, leading to the suggestion that Ga might be a promising new therapeutic for the treatment of infection with P. aeruginonsa. (2007-03-15)

Bacteriophages battle superbugs
IFR microbiologists are reinvigorating a way of battling C. difficile infections that they hope will help overcome the growing problem of antibiotic resistant superbugs in hospitals. (2013-07-18)

Cryo-electron tomography reveals uromodulin's role in urinary tract infection protection
Free-flowing filaments of Uromodulin protect against urinary tract infections (UTIs) by duping potentially harmful bacteria to attach to their fishbone-like molecular architecture - rather than to sensitive urinary tract tissues - before being flushed out of the body during urination, researchers report. (2020-07-02)

Scientists identify 'first responders' to bacterial invasion
When bacteria enter our body, they kick-start a powerful immune response. But this chain of reactions doesn't fully account for our immediate responses. Researchers at KU Leuven, Belgium, show that so-called ion channels play a key role as 'first responders'. (2017-10-23)

The tightest non-aminoglycoside ligand for the bacterial ribosomal RNA A-site
A research group at Tohoku University has made a significant discovery with positive implications for the development of bacteria-fighting drugs. The aminoacyl-tRNA site (A-site) of the 16S RNA decoding region in the bacterial ribosome looks promising for a new era of antibiotic drug development. (2018-10-15)

Viral proteins may prevent bacterial infections
Researchers from Rockefeller University are enlisting proteins produced by viruses in a novel strategy that may someday help prevent bacterial infections in hospitals and nursing homes. (2004-08-05)

Hypoxic mucus favors Pseudomonas infections in cystic fibrosis
Cystic fibrosis (CF) is life-threatening primarily because the lungs of affected individuals are subject to persistent and intractable infections, typically with Pseudomonas aeruginosa. The properties of the tracheal fluids that support these infections has been a matter of considerable interest. Surprisingly, less attention has been paid to the properties of P. aeruginosa itself as it exists within the airway epithelium. (2002-01-30)

Catch 22: Immune systems protect hosts, but drive bacterial evolution
Immune systems that develop only partial immunity to a bacterial pathogen drive the evolution of more potent strains of the bacteria, a new study in house finches reveals. (2018-03-01)

How bacteria get from catheter to patient
Patients in hospitals can develop infections as a result of contamination of indwelling medical devices such as catheters with bacteria that are normal inhabitants of the skin of the patient or health care personnel. The bacterium Staphylococcus epidermidis is a major cause of such infections. Researchers have now identified the bacterial products that enable Staphylococcus epidermidis to get from catheter to patient, providing potential new targets for preventing such infections. (2010-12-06)

New high-speed test shows how antibiotics combine to kill bacteria
Researchers at Uppsala University have developed a new method to determine - rapidly, easily and cheaply - how effective two antibiotics combined can be in stopping bacterial growth. The new method is simple for laboratories to use and can provide greater scope for customising treatment of bacterial infections. The study is published in PLOS Biology. (2020-09-17)

Pneumococcal vaccine could prevent numerous deaths, save costs during a flu pandemic, model predicts
A new predictive model shows that vaccinating infants with 7 valent pneumococcal conjugate vaccine -- the current recommendation--not only saves lives and money during a normal flu season by preventing related bacterial infections; it also would prevent more than 357,000 deaths during an influenza pandemic, while saving $7 billion in costs. (2008-10-28)

No hiding place for infecting bacteria
Scientists in Colorado have discovered a new approach to prevent bacterial infections from taking hold. Writing in the Journal of Medical Microbiology, Dr. Quinn Parks and colleagues describe how they used enzymes against products of the body's own defense cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm which enables them to avoid both the body's immune mechanisms and antibiotics. (2009-03-15)

Computer model better than clinical judgment for diagnosing fever in young children
A computerized diagnostic model outperforms clinical judgment for the diagnosis of fever in young children, and may improve early treatment, finds a study published on today. (2010-04-20)

Adhesive tape connected to hospital infections
Adhesive tape used to secure intravenous catheters may transmit bacteria that contribute to hospital infections, according to a University of Toronto study in the current edition of the Journal of General Internal Medicine. (1999-07-27)

Researchers developing new tool to distinguish between viral, bacterial infections
Antibiotics are lifesaving drugs, but overuse is leading to antibiotic resistance, one of the world's most pressing health threats. Scientists identified 11 genetic markers in blood that accurately distinguished between viral and bacterial infections 80 to 90 percent of the time. The finding is important because physicians don't have a good way to confirm bacterial infections like pneumonia and more-often-than-not default to an antibiotic. (2017-07-28)

Study finds low hand hygiene compliance rates during anesthesia administration
Anesthesia providers are missing opportunities to clean their hands during surgical procedures, according to a study published in the July issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology. (2014-06-30)

Study investigates whether it is safe for GPs to prescribe fewer antibiotics
A new study has found that reducing antibiotic prescribing for respiratory tract infections -- such as coughs, colds, sore throats and ear infections -- is not linked to an increase in the most serious bacterial complications, such as bacterial meningitis. The study, published in the BMJ, investigated whether reducing antibiotic prescribing for people attending their GP with respiratory tract infections could have an effect on safety. (2016-07-04)

UQ scientists close in on first dengue treatment
Clinical trials for a dengue fever treatment could start within a year, following a discovery by University of Queensland scientists. UQ's School of Chemistry and Molecular Biosciences Head Professor Paul Young said the researchers had identified similarities in how the body reacted to dengue virus and bacterial infections, in a finding that would allow them to repurpose existing drugs. (2015-09-09)

Compound for Alzheimer's combats bacterial resistance to last-resort antibiotics in mice
An experimental drug for neurodegenerative diseases can also reverse resistance to ''last-resort'' polymyxin antibiotics among bacteria that cause sepsis, a life-threatening complication from infections. (2020-11-18)

Monash helps address superbug resistance with Phage therapy
International research involving a Monash biologist shows that bacteriophage therapy -- a process whereby bacterial viruses attack and destroy specific strains of bacteria -- can be used successfully to treat systemic, multidrug resistant bacterial infections. (2017-08-15)

Potential new test to detect serious bacterial infections including meningitis and sepsis
Scientists have identified two genes that are switched on only when a child is suffering from a bacterial infection. This could allow doctors to quickly distinguish between a viral or bacterial illness, and identify early cases of potentially deadly infections. (2016-08-23)

What gives us sunburn protects crayfish against bacteria
The production of melanin gives us sunburns, but it also helps invertebrate animals to encapsulate attacking fungi and parasites. Uppsala University researchers, in collaboration with Korean and Thai colleagues, can now show that melanin also protects against bacterial infections, at least in crayfish. The study is published in the latest net edition of Journal of Biological Chemistry. (2007-09-24)

Call for further study on meningococcal vaccine
An ANU specialist has called for more research into the effect of the routine meningococcal vaccine on other throat and nasal infections found in the community, like sore throats, ear infections, tonsillitis and pneumonia. (2007-02-14)

Antibiotics not always beneficial for childhood ear infections
More children are treated in the U.S. with antibiotics for inflammation of the middle ear, or otitis media, than any other child health problem. More than five million cases are diagnosed every year. But now, a scholarly review of over one hundred studies by a U.Va. pediatrician concludes that antibiotics help only one in eight children with ear infections. (2002-10-10)

Using viruses to beat superbugs
Viruses that can target and destroy bacteria have the potential to be an effective strategy for tackling hard-to-treat bacterial infections. The development of such novel therapies is being accelerated in response to growing antibiotic resistance, says Dr. David Harper at the Society for General Microbiology's Spring Conference in Dublin. (2012-03-25)

New contrast agents detect bacterial infections with high sensitivity and specificity
Novel contrast agents that sneak into bacteria disguised as glucose food can detect bacterial infections in animals with high sensitivity and specificity. These agents -- called maltodextrin-based imaging probes -- can also distinguish a bacterial infection from other inflammatory conditions. (2011-07-18)

Researchers find way to kill pathogen resistant to antibiotics
Nagoya University researchers and colleagues in Japan have demonstrated a new strategy in fighting antibiotics resistance: the use of artificial haem proteins as a Trojan horse to selectively deliver antimicrobials to target bacteria, enabling their specific and effective sterilization. The technique killed 99.9% of Pseudomonas aeruginosa, a potentially deadly, antibiotic-resistant bacterium present in hospitals. The strategy should also work for other dangerous bacteria. The research paper announcing the breakthrough was published in ACS Chemical Biology. (2019-09-20)

Immune cells support good gut bacteria in fight against harmful bacteria
The immune cell protein ID2 is critical for the maintenance of healthy gut microbiota, helping good bacteria fight off harmful bacteria. This study, published in Immunity, shows how the immune system shapes the gut microbiota to limit infections. (2015-04-21)

Pitt receives $4.7 million award to reduce hospital-acquired infections
The University of Pittsburgh School of Medicine has received a four-year, $4.7 million grant from the Pennsylvania Department of Health to find new ways to stop deadly hospital-acquired infections that often are resistant to treatment. The grant, funded by Pennsylvania's share of the national 2008-2009 tobacco settlement, will focus on C. difficile, A. baumannii and the drug-resistant bacteria known as MRSA, which cause tens of thousands of deaths in the US every year. (2009-03-18)

Blood test could avoid inappropriate use of antibiotics for respiratory infections (pp 600)
A rapid blood test to help distinguish between bacterial and other (predominantly viral) infections could substantially reduce the inappropriate use of antibiotics for common infections, conclude authors of a study in this week's issue of THE LANCET. (2004-02-18)

'Resuscitating' antibiotics to overcome drug resistance
Combining common antibiotics with additional compounds could make previously resistant bacteria more susceptible to the same antibiotics. 'Resuscitation' of existing antibiotics has the potential to make infections caused by multidrug-resistant bacteria easier to control, reducing antibiotic usage and levels of antimicrobial resistance, say scientists presenting their work at the Society for General Microbiology's Spring Conference in Dublin this week. (2012-03-27)

Impact of protective bacteria linked to infection route, study finds
The benefits of protective bacteria -- which safeguard organisms from further disease without causing harm -- depend on how subsequent infections enter the body, a study of fruit flies has shown. (2017-06-06)

Strategies to decrease bacterial colonization
Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. In her doctoral thesis, chemist Shoghik Hakbyan has studied ways to decrease the bacterial colonization at Umeå University in Sweden. (2015-09-14)

Recent research uncovers surprises about antibiotic resistance
It's thought that antibiotic resistance is associated with a fitness cost, meaning that bacteria that develop antibiotic resistance must sacrifice something in order to do so. Because of this, proper use of antibiotics should result in susceptible strains eventually replacing resistant ones. (2016-06-07)

Researchers discover how fatal biofilms form
By severely curtailing the effects of antibiotics, the formation of organized communities of bacterial cells known as biofilms can be deadly during surgeries and in urinary tract infections. Yale researchers have just come a lot closer to understanding how these biofilms develop, and potentially how to stop them. (2018-10-05)

Making sense of bacterial biodiversity
An article in Ecology Letters this month, reports that primary productivity can influence the diversity of bacterial communities. Increasing primary productivity can alter the number of taxonomic groups of bacteria present, and the response can vary among different bacterial taxonomic groups. Bacteria may comprise the majority of the earth's biodiversity, and understanding the relationship between primary productivity and bacterial diversity is an important step toward understanding the processes responsible for the maintenance of bacterial biodiversity. (2003-07-02)

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