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Cooperation between cancer cells makes therapies ineffective, suggests new treatment
New research from the University of East Anglia shows why many cancers are difficult to treat and come back following treatment. Scientists have shown that cancer cells cooperate with each other in the production of growth factors (molecules produced by the cancer cells that are essential for tumor progression). It is hoped that the findings will lead to a new type of treatment involving genetically modified cancer cells being reinserted into a tumor. (2015-01-26)

New strategy to attack tumor-feeding blood vessels
Scientists at the Walter and Eliza Hall Institute have discovered a key molecule needed to kill the blood vessels that supply tumors. The research team from the institute's Molecular Genetics of Cancer and Cancer and Haematology divisions found that for anti-cancer therapies that target tumor blood vessels to work the death- inducing molecule Bim is required. The finding could lead to improved anti-cancer treatments that are based on a two- or three-pronged attack on both the tumor and its blood supply. (2011-06-06)

FAU researchers take new approach to determining risk of cancer reoccurring
What is the likelihood of a patient developing cancer again after having a tumor removed? This is the question that experts in medicine and medical informatics at Friedrich-Alexander-Universität (FAU) aim to find answers to in a new research project in which they will be researching micrometastases that can form new tumors years after skin cancer, for example, has been treated successfully. The project will be funded with a total of 1.3 million euros over the next three years. (2016-07-11)

£2million project aims to revolutionize the study of cancer cells in the lab
Researchers from Queen Mary, University of London have been awarded a €2.43million grant from the European Research Council for a project which aims to revolutionize the field of cancer cell research by using bioengineering techniques to grow the first complex 3-dimensional human 'tumor microenvironment' in the laboratory. (2013-04-22)

No viral cause for breast cancer and brain tumors
A major study conducted at the Sahlgrenska Academy has now disproved theories of a viral cause for breast cancer and the brain tumor, glioblastoma. The study, which was based on over seven billion DNA sequences and which is published in Nature Communications, found no genetic traces of viruses in these forms of cancer. (2013-10-08)

Research brings us nearer to understanding how neuro cells turn cancerous
Scientists from the Sloan-Kettering Institute for Cancer Research in New York with the help of Plymouth University Peninsula Schools of Medicine and Dentistry have completed research which for the first time brings us nearer to understanding how some cells in the brain and nervous system become cancerous. (2014-07-22)

Cushing's syndrome: LCSB researchers characterize a new tumor syndrome
Scientists at the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have published their findings that mutations in a gene known as 'ARMC5' promote the growth of benign tumors in the adrenal glands and on the meninges: ARMC5 appears to belong to the group of so-called tumor suppressor genes. It is the first time in years that scientists have characterized such a gene. (2014-10-13)

Understanding brain tumor growth opens door for non-surgical treatment
Researchers from Plymouth University Peninsula Schools of Medicine and Dentistry have for the first time identified a new group of growth factor receptors for brain tumors. Understanding how these work could mean that existing drugs could be used as alternative therapy to surgery or radiotherapy for patients with multiple brain tumors. (2013-01-14)

Wavelets crunch through doctors' day long struggle to diagnose brain tumors
Today if doctors devote a full day to analysis and expert thought, they may be able to provide just half a dozen patients with a diagnosis of the precise type of brain tumor they face. Now researchers at the University of Warwick have devised an automated technique that can give a preliminary analysis of the precise brain tumor type within seconds. (2008-06-17)

Researchers map brain tumor cells' adaptation to oxygen deprivation
The most aggressive variant of brain tumor -- glioblastoma -- has an average survival rate of 15 months. There is therefore an urgent need for new treatment strategies for this group of patients. A research team from Lund University in Sweden has now identified new factors which may affect the tumor cells' ability to resist treatment. The study has been published in Cell Reports. (2017-08-16)

New technique to help brain cancer patients
A new scanning technique developed by Danish and US researchers reveals how susceptible patients with aggressive brain cancer are to the drugs they receive. The research behind the ground-breaking technique has just been published in Nature Medicine. (2013-08-23)

A traditional Japanese art inspires a futuristic innovation: Brain 'organoids'
The ancient Japanese art of flower arranging was the inspiration for a groundbreaking technique to create tiny 'artificial brains' that could be used to develop personalized cancer treatments. (2016-12-05)

Shrinking brain tumours and opening the door for targeted cancer therapies
A new drug, known as IP1867B, could be used for future treatments of brain tumours. The research team showed that IP1867B worked with existing cancer treatments boosting their effectiveness and, in some cases, restored sensitivity to some treatments. (2019-08-05)

University of Calgary research leads to brain cancer clinical trial
Researchers at the University of Calgary have made a discovery that could prolong the life of people living with glioblastoma -- the most aggressive type of brain cancer. The research was published in Clinical Cancer Research, and is leading researchers to start a human phase I/II clinical trial as early as spring 2015. (2014-10-14)

High-dose radiotherapy could reduce cognitive function for people with low-grade brain tumours
Dutch authors of a study in this week's issue of The Lancet caution against the use of high-level radiation for the treatment of low-grade brain tumours-as such treatment does not improve survival and may contribute to cognitive decline. The authors also comment that the tumour itself is the main cause of cognitive impairment, and that other factors-notably the use of antiepileptic drugs-may play a role in reducing cognitive function. (2002-10-31)

Whole-brain radiotherapy after surgery or radiosurgery not recommended for brain metastases
Whole-brain radiotherapy should not be given routinely to all patients whose cancer has spread to the brain. (2009-09-21)

Childhood cancer: The four survival strategies of tumor cells
Cancer cells in children tend to develop by following four main trajectories -- and two of them are linked to relapse of the disease, research led by Lund University in Sweden shows. The four strategies can occur simultaneously in a single tumor, according to the study that is now published in Nature Genetics. (2018-06-04)

Plant extract fights brain tumor
Silibinin from milk thistle seeds could be a novel, non-invasive treatment strategy for Cushing Disease. (2015-02-11)

Breakthrough in brain cancer research made by Newcastle experts
Scientists at Newcastle University, UK, have made a pioneering breakthrough in the understanding of how a fatal brain tumour grows -- which could lead to improved treatments for patients. (2016-06-29)

Microchip patented which separates and extracts tumor cells in the blood
Ikerlan-IK4 and Mondragón Unibertsitatea are taking part in a project initiated by the Spanish National Research Council, CSIC, and which has developed a microchip capable of separating and extracting tumor cells in the blood stream by means of ultrasonic waves. The Foundation General Hospital of the University of Elche, together with researcher Alfredo Carrato, has also collaborated on this project. (2010-10-21)

Detecting brain infections without surgery
Researchers at Westmead Millennium Institute have discovered a safe, non-surgical method of identifying brain infections such as brain abscess, and an accurate and rapid way of diagnosing meningitis. (2005-09-07)

Researchers identify potential new strategy to treat ovarian cancer
Scientists studying cancerous tumor tissues in a laboratory believe they have identified a potential new strategy to treat ovarian cancer -- which affects around 7,000 women in the UK each year. (2014-04-28)

Nottingham scientists identify childhood brain cancer genes
Scientists at the University of Nottingham have isolated three important genes involved in the development of a type of childhood brain cancer. The breakthrough is revealed in a study published in the British Journal of Cancer today (Tuesday). (2008-09-15)

New research could stop tumor cells from spreading
Researchers from the department of chemistry and molecular biology at the University of Gothenburg have managed for the first time to obtain detailed information about the role of the protein metastasin in the spread of tumor cells. Published recently in the renowned Proceedings of the National Academy of Sciences, the study paves the way for the development of new drugs. (2012-04-02)

Physics of tumours: Cancer cells become fluidised and squeeze through tissue
Working with colleagues from Germany and the US, researchers at Leipzig University have achieved a breakthrough in research into how cancer cells spread. The team of biophysicists led by Professor Josef Alfons Käs, Steffen Grosser and Jürgen Lippoldt demonstrated for the first time how cells deform in order to move in dense tumour tissues and squeeze past neighbouring cells. They have now published their findings in 'Physical Review X'. (2021-02-18)

Cancer cells 'corrupt' their healthy neighbors
The healthy cells immediately surrounding a tumor become more stem cell-like and support cancer growth, reveals a new study published in Nature. (2019-08-28)

Research funding for teen brain and nervous system cancer
Scientists from Plymouth University Peninsula Schools of Medicine and Dentistry have been awarded a grant from young person's cancer charity The Laura Crane Youth Cancer Trust to investigate a new drug-based treatment for a multi-tumor brain and nervous system cancer which affects teenagers and young adults. (2014-11-05)

Researchers discover the Achilles' heel of an aggressive brain cancer
Researchers from the University of Helsinki, Finland, have discovered a chink in the armor of the tumor cells of glioblastoma, a lethal brain cancer. Alongside the finding, the researchers also came up with a method for attacking this vulnerability. The results gained in experiments conducted with cell cultures and a mouse model are promising. (2019-05-10)

Aggressive brain tumor could be diagnosed with simple blood test in future
New research by Sussex scientists could be the first step towards developing a blood test to diagnose the most aggressive type of brain tumor, known as glioblastoma. (2019-08-19)

New ways to treat solid tumors
An international team of scientists has shown that an antibody against the protein EphA3, found in the micro-environment of solid cancers, has anti-tumor effects. (2014-08-15)

New toolkit reveals novel cancer genes
A new statistical model has enabled researchers to pinpoint 27 novel genes thought to prevent cancer from forming, in an analysis of over 2,000 tumors across 12 human cancer types. The findings could help create new cancer treatments that target these genes, and open up other avenues of cancer research. (2017-10-31)

Scientists discover how breast cancer cells spread from blood vessels
Researchers have identified a protein that controls how breast cancer cells spread around the body. (2016-02-09)

Cancer tumours form surprising connections with healthy brain cells
Anti-epileptic medicine can curb the dangerous communication and possibly be part of future treatment. (2019-09-27)

Technique that makes brain tumours fluoresce improves surgical outcome
A new technique that causes brain tumours to fluoresce results in more complete removal of the tumour and in improved progression-free survival, report German researchers in the May issue of The Lancet Oncology. (2006-04-26)

Estimating the risk of cancer
Dutch scientists have developed a new tumour growth model in which the tumour is a part of the host's body. The model reveals that a low-calorie diet delays the growth of a tumour, and thus increases the life expectancy. Furthermore, tumours were found to develop faster in younger than in older hosts. (2003-12-19)

Breaking through a tumor's defenses
In research published today, Babraham Institute researchers have shown that some tumors use not one but two levels of protection against the immune system. Knocking out one level boosted the protective effects of the second and vice versa. The research demonstrates that a two-pronged approach targeting both cell types simultaneously may offer a promising route for the development of new cancer immunotherapies. (2018-06-07)

Ecoendoscopy in cancer of the pancreas
Cancer of the pancreas is the number five in the list of deaths due to cancers and the third causing deaths due to digestive tumour in Spain. The survival rate for patients with which it is possible to carry out a complete resection of the tumour does not reach 25 percent within five years. (2005-11-24)

Plymouth to become Brain Tumour Research center of excellence
Plymouth University Peninsula Schools of Medicine and Dentistry is to become the next center of research excellence for charity Brain Tumour Research. (2014-03-03)

Engineering a new cancer detection tool
E. coli may have potentially harmful effects but scientists in Australia have discovered this bacterium produces a toxin which binds to an unusual sugar that is part of carbohydrate structures present on cells not usually produced by healthy cells. This structure is a known tumor antigen leading scientists to develop a new cancer detection tool. (2017-06-07)

Biosynthetic capacity: The key to switch-off cancer stem cells
The Colorectal Cancer Lab at IRB Barcelona identifies the capacity to synthesize proteins (or biosynthetic capacity) as a key property for the regenerative potential of colon cancer cells. Published in Cell Stem Cell, the study proposes a new therapeutic focus for the scientific community and the pharmaceutical industry to explore. (2020-05-12)

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