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Researchers chart global genetic interaction networks in human cancer cells
Study identifies genetic networks in human cells and potential targets for cancer therapy. (2017-02-02)

New technology to aid crystallization prediction
Software designed to assist companies in overcoming common issues associated with crystal formation may be on the market within a year. (2012-03-16)

Pioneering new technique could boost understanding of causes of heart disease
The complex and mysterious mechanisms that drive communication and reactions within human cells could be on the verge of being unravelled, due to a pioneering new technique. (2018-01-09)

Liquid light switch could enable more powerful electronics
Researchers have built a record energy-efficient switch, which uses the interplay of electricity and a liquid form of light, in semiconductor microchips. The device could form the foundation of future signal processing and information technologies, making electronics even more efficient. (2016-08-08)

Combining images and genetic data proves gene loss behind aggressive ovarian cancers
Cancer Research UK scientists have shown that loss of a gene called PTEN triggers some cases of an aggressive form of ovarian cancer, called high-grade serous ovarian cancer. (2014-12-16)

Scientists explore the physics of bumpy roads
Just about any road with a loose surface -- sand or gravel or snow -- develops ripples that make driving a very shaky experience. A team of physicists from Canada, France and the United Kingdom have recreated this (2009-07-07)

Prehistoric origins of stomach ulcers uncovered
Scientists have discovered that the ubiquitous bacteria that causes most painful stomach ulcers has been present in the human digestive system since modern man migrated from Africa over 60,000 years ago. They compared DNA sequence patterns of humans and the Helicobacter pylori bacteria now known to cause most stomach ulcers and found that the genetic differences between human populations that arose as they dispersed from Eastern Africa over thousands of years are mirrored in H.pylori. (2007-02-07)

CrystEngComm celebrates the CSD in a special issue
The journal CrystEngComm has published a special issue to mark the Cambridge Structural Database (CSD) reaching 1 million structures, with 33 papers that highlight the breadth of applications made possible with this data. (2020-11-10)

Reprogrammed cells reduce Parkinson's symptoms in rats
This is the first demonstration that neurons derived from reprogrammed cells can integrate into an adult animal brain and improve symptoms of a neurodegenerative disease. The results may indicate a path to future therapeutic use in human patients, once hurdles associated with reprogramming adult cells have been addressed. (2008-04-07)

Quick-change materials break the silicon speed limit for computers
Faster, smaller, greener computers, capable of processing information up to 1,000 times faster than currently available models, could be made possible by replacing silicon with materials that can switch back and forth between different electrical states. (2014-09-19)

How Reliable Are League Tables?
Marshall and Spiegelhalter describe a new statistical technique that can be used to quantify the uncertainty about ranking. They find that rankings were not entirely meaningful and therefore it would be unwise to take them too seriously. Positions in ranking can alter radically year on year, but this does not necessarity mean that a significant change in the success rate has occured. (1998-06-05)

Scientists develop very early stage human embryonic stem cell lines for first time
Scientists at the University of Cambridge have for the first time shown that it is possible to derive from a human embryo so-called 'naïve' pluripotent stem cells -- one of the most flexible types of stem cell, which can develop into all human tissue other than the placenta. (2016-03-04)

Yeast spotlights genetic variation's link to drug resistance
Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists at the Wellcome Trust Sanger Institute and the Institute for Research on Cancer and Ageing of Nice in France, show that high genetic diversity can prime new mutations that cause drug resistance. The study published today in Cell Reports has implications for our understanding of the evolution of resistance to antimicrobial and anticancer drugs. (2017-10-17)

Can researchers engage safely with the food industry?
Researchers from The University of Queensland and University of Cambridge are exploring ways to help scientists better protect their work from the influence of the food industry. (2019-08-23)

Rapid genome sequencing and screening help hospital manage COVID-19 outbreaks
Cambridge researchers have shown how rapid genome sequencing of virus samples and enhanced testing of hospital staff can help to identify clusters of healthcare-associated COVID-19 infections. (2020-07-14)

Aesop's Fable unlocks how we think
Cambridge scientists have used an age-old fable to help illustrate how we think differently to other animals. (2012-07-25)

Initiative launched to tackle future of communications
The Cambridge-MIT Institute (CMI) is today (Tuesday 15 June 2004) launching a new initiative to promote the progress of the entire communications industry and usher in a new era of innovation. (2004-06-15)

Here comes the sun...
New solar cells could increase the maximum efficiency of solar panels by over 25 percent, according to scientists from the University of Cambridge. (2012-02-08)

Striking differences revealed in COVID-19 mortality between NHS trusts
A University of Cambridge team led by Professor Mihaela van der Schaar and intensive care consultant Dr Ari Ercole of the Cambridge Centre for AI in Medicine (CCAIM) is calling for urgent research into the striking differences in COVID-19 deaths they have discovered between the intensive care units of NHS trusts across England. (2020-06-23)

Scientists discover how proteins in the brain build-up rapidly in Alzheimer's
Cambridge researchers have identified -- and shown that it may be possible to control -- the mechanism that leads to the rapid build-up of the disease-causing 'plaques' that are characteristic of Alzheimer's disease. (2016-07-18)

Pandemic influenza may cause an extra 62 million deaths a year
Using mortality data from the 1918-20 influenza pandemic, researchers have predicted that 62 million people -- 96 percent from the developing world -- could die in a year if a similar pandemic were to occur today. They report their findings in an Article in this week's issue of the Lancet. (2006-12-21)

Could genetics help explain intellectual disability in children?
Teams of leading UK scientists have joined forces to unlock an untapped source of genetic information in a bid to better understand and treat children with Intellectual Disability. (2014-06-23)

Tiny juvenile dinosaur fossil sheds light on evolution of plant eaters
Scientists from London, Cambridge and Chicago have identified one of the smallest dinosaur skulls ever discovered as coming from a very young Heterodontosaurus, an early dinosaur. This juvenile weighed about 200 grams. This skull suggests how and when the family of herbivorous dinosaurs that includes Heterodontosaurus made the transition from eating meat to eating plants. (2008-10-23)

Bacterial chemical 'signatures' a sign of damaged gut microbiome in critical illness
Chemicals produced by healthy bacteria could be used to assess the health of the gut microbiome and help identify critically-ill children at greatest risk of organ failure, a study published in Critical Care Medicine has found. (2019-06-13)

Pitcher plant uses rain drops to capture prey
During heavy rain, the lid of Nepenthes gracilis pitchers acts like a springboard, catapulting insects that seek shelter on its underside directly into the fluid-filled pitcher, new research has found. The findings were published today, Wednesday 13 June, in the journal PLoS ONE. (2012-06-13)

Immune system discovery could aid fight against TB
A key aspect of how the body kicks the immune system into action against tuberculosis is revealed in research published today. The authors, writing in Science, hope that their research could aid the development of novel vaccines and immunotherapies to combat TB, which is responsible for two million deaths each year. (2006-10-19)

New drug targets for lethal brain cancer discovered
More than 200 genes with novel and known roles in glioblastoma - the most aggressive type of brain cancer - offer promising new drug targets. Researchers from the Sanger Institute and their collaborators engineered a new mouse model to show for the first time how a mutation in the well-known cancer gene, EGFR initiates glioblastoma, and works with a selection from more than 200 other genes to drive the cancer. (2020-07-29)

Clean correction of a patient's genetic mutation
For the first time, scientists have cleanly corrected a gene mutation in a patient's stem cells, bringing the possibility of patient-specific therapies closer to reality. The team, led by researchers from the Wellcome Trust Sanger Institute and the University of Cambridge, targeted a mutation responsible for cirrhotic liver disease and lung emphysema. Using cutting-edge methods, they corrected the sequence of a patient's genome, removed all exogenous DNA and showed that the gene worked normally. (2011-10-12)

3D-printed corals provide more fertile ground for algae growth
Researchers have 3D-printed coral-inspired structures that are capable of growing dense populations of microscopic algae. The work could lead to the development of compact, more efficient bioreactors for producing algae-based biofuels, as well as new techniques to repair and restore coral reefs. (2020-04-09)

Study shows inappropriate antibiotic prescribing differs by patient age, insurance, race
A patient's age and race are associated with risk of receiving an unneeded antibiotic prescription for upper respiratory conditions caused by viruses, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. Additionally, the study found that advanced practice providers, such as nurse practitioners and physician assistants, are 15 percent more likely than physician providers to prescribe antibiotics to adults. (2018-01-30)

New research links International Monetary Fund loans with higher death rates from tuberculosis
International Monetary Fund loans were associated with a 16.6 percent rise in death rates from tuberculosis in the former Soviet Union and Central and Eastern European countries between 1992 and 2002, finds a study in this week's PLoS Medicine. The study also found that IMF loans were linked with a 13.9 percent increase in the number of new cases of TB per year and a 13.2 percent increase per year in the total number of people with the disease. (2008-07-21)

Elephant poaching costs African economies $25 million per year in lost tourism revenue
Elephant poaching costs African countries around $25 million annually in lost tourism revenue, according to a new study. Comparing this loss with the cost of halting declines in elephant populations, the study determines that investment in conservation is economically favorable across the majority of elephants' range. (2016-11-01)

Policing: 2 officers 'on the beat' prevent 86 assaults and save thousands in prison costs
The results of a major criminology experiment in Peterborough suggest that investing in proactive PCSO foot patrols targeting crime 'hot spots' could yield a more than five-to-one return: with every £10 spent saving £56 in prison costs. (2016-06-14)

Revolutionary solar cells double as lasers
Latest research finds that the trailblazing 'perovskite' material used in solar cells can double up as a laser, strongly suggesting the astonishing efficiency levels already achieved in these cells is only part of the journey. (2014-03-28)

Twanging rat whiskers yields insight into sensing machinery
High-speed video of rats using their whiskers to explore different surfaces has given researchers significant insights into the subtle mechanics of their tactile sensory system. (2008-02-27)

Variations in cell programs control cancer and normal stem cells
In the breast, cancer stem cells and normal stem cells can arise from different cell types and tap into distinct yet related stem cell programs, according to Whitehead Institute researchers. The differences between these stem cell programs may be significant enough to be exploited by future therapeutics. (2015-09-03)

Novel genetic mutations cause low metabolic rate and obesity
Researchers from the University of Cambridge have discovered a novel genetic cause of severe obesity which, although relatively rare, demonstrates for the first time that genes can reduce basal metabolic rate -- how the body burns calories. (2013-10-24)

Sex chromosome shocker: The 'female' X a key contributor to sperm production
Painstaking new analysis of the genetic sequence of the X chromosome--long perceived as the (2013-07-21)

lobSTR algorithm rolls DNA fingerprinting into 21st century
Whitehead Institute researchers have created a three-step algorithm, lobSTR, that in one day accurately and simultaneously profiles more than 100,000 short tandem repeats in one human genome sequence -- a feat that previous systems could never complete. (2012-04-27)

Fake news 'vaccine': Online game may 'inoculate' by simulating propaganda tactics
A new experiment, launching today online, aims to help 'inoculate' against disinformation by providing a small dose of perspective from a (2018-02-19)

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