Cell Culture Current Events

Cell Culture Current Events, Cell Culture News Articles.
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A new route to branching morphogenesis
Branching morphogenesis, one of the unifying themes in organogenesis, allows a cluster of epithelial cells to generate a system of branching tubules and ducts, rather than a simple, flat sheet. This event can be recapitulated in 3-dimensional culture systems, when spontaneously formed kidney, lung, or mammary cell aggregates are treated with HGF or any of several other agents. (2002-02-13)

GroPep announces Japanese approval of biopharmaceutical that uses its cell culture products
Adelaide biotechnology company, GroPep, announced today that a biopharmaceutical product - with a key manufacturing ingredient supplied by GroPep - has received regulatory approval in Japan. The product is the sixth biopharmaceutical made with GroPep's Cell Culture Products to have achieved regulatory approval. (2005-04-22)

Innovative solutions for lab-automation developed by Bioprocess Engineers from Dresden
The lab automation platform PetriJet developed at the TU Dresden, Chair of Bioprocess Engineering equipped with one input and one output stack respectively handles up to 20 culture dishes per batch which results in about 100 handled culture dishes and taken images per hour. (2014-03-31)

Michael Betenbaugh wins 2010 Cell Culture Engineering award
This prestigious award is to recognize outstanding contributions to the field of Cell Culture Technology and Engineering, and significant service and dedication to the profession. The award was established in 2001 and is given bi-annually at the Cell Culture Engineering Conference. (2010-04-08)

'Hydra's Tale' examines disgust in literature, art and history
University of Alberta Professor Robert Wilson has written and published a new book entitled, Hydra's Tale: Imagining Disgust. This work examines the notion and 'disgust' throughout literature, art and history. (2002-06-28)

GroPep announces US FDA approval of biopharmaceutical that uses its cell culture product
Biopharmaceutical company, GroPep Limited, announced today that a biopharmaceutical - with a key raw material ingredient supplied by GroPep - has received regulatory approval in the USA. The drug is the seventh biopharmaceutical made with GroPep's Cell Culture Products to have achieved regulatory approval. (2005-06-02)

A shake-up in cell culturing: Flame sterilization may affect the culture
Researchers from the University of Tsukuba have found that flame-sterilizing shake-flasks, to avoid introducing microbial contaminants, considerably increases the carbon dioxide concentration in the flasks. This enhanced carbon dioxide concentration affects the growth of some microbial species, which may affect the quantity of vaccines or other valuable substances produced by the microbes. (2020-07-01)

Cell Culture Engineering
Since the 1980s, animal cell culture technology has become essential for the production of an ever-increasing number of human and veterinary biopharmaceuticals. These bi-annual Cell Culture Engineering conferences are a leading venue for the academic, industrial and regulatory communities to learn and debate new concepts and issues related to animal cell culture research and development. (2008-02-26)

CNS cell death in bacterial meningitis
Bacterial infection of the CNS is hazardous not only because of its often-lethal acute effects, but also because it leads to the death of irreplaceable neurons and glia. Braun et al. have established microglial and neuronal cell culture systems in which to study the mechanisms by which Pneumococcus bacteria induce cell death. (2002-01-02)

Growing stem cells on a chip
A team of researchers has developed a chip-like plate on which hPSCs can be raised in optimal, 3-D conditions. (2016-10-24)

Natural Products Discovery and Production
This conference will use a cross-disciplinary approach to explore the present and future status of natural products and their prospects for continued commercialization. It will focus on a comprehensive view of recent developments impacting the discovery and production of natural products. (2008-02-22)

Dartmouth scientists develop protocol to harvest mouse cell lines for melanoma research
Dartmouth researchers have developed a protocol that permits cells harvested from melanoma tumors in mice to grow readily in cell culture. (2014-01-31)

Cancer patient, heal thyself
Anti-cancer immune cells are found in cancer patients, but fail to reject tumors. In the July 1 issue of the Journal of Clinical Investigation, researchers from the German Cancer Research Center, provide a method to make these cells very effective at infiltrating tumor transplants and in reducing tumor size in mice. This is a potential immunotherapy strategy for cancer treatment with appropriately reactivated anti-tumor-specific T cell subsets that already exist in patients' own body. (2004-07-01)

Culturing cheaper stem cells
Human pluripotent stem cells (hPSCs) can infinitely self-renew and develop into all major cell types in the body, making them important for organ repair and replacement. But culturing them in large quantities can be expensive. Now, scientists at Japan's Kyoto University, with colleagues in India and Iran, have developed a more cost-effective culture by using a new combination of chemical compounds. (2018-03-05)

Transcending tradition
A companion to the international exhibition (2011-12-13)

Key protein reveals secret of stem cell pluripotency
A protein that helps maintain mouse stem cell pluripotency has been identified by researchers at the RIKEN Omics Science Center. The finding, published in the August issue of Stem Cells (first published online July 26, 2011), points the way to advances in regenerative medicine and more effective culturing techniques for human pluripotent stem cells. (2011-09-05)

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology. In an upcoming PLoS ONE paper, researchers, including Andras Paldi, in Genethon (Evry, France) report, on the basis of experimental observations and computer simulations, that the stem cell identity in culture may strongly depend on the cellular microenvironment. (2007-04-24)

IU researchers create the inner ear from stem cells, opening potential for new treatments
Indiana University scientists have transformed mouse embryonic stem cells into key structures of the inner ear. The discovery provides new insights into the sensory organ's developmental process and sets the stage for laboratory models of disease, drug discovery and potential treatments for hearing loss and balance disorders. (2013-07-10)

UBC-led team develops platform to monitor hematopoietic stem cells
A Canadian research team has developed an automated microfluidic cell culture platform to monitor the growth, survival and responses of hundreds of hematopoietic stem cells (HSCs) at the single cell level. (2011-05-22)

A nanofiber matrix for healing
A new nanofiber-on-microfiber matrix could help produce more and better quality stem cells for disease treatment and regenerative therapies. (2017-02-14)

Screening for transformed human mesenchymal stromal cells with tumorigenic potential
Spontaneous transformation of human mesenchymal stem/stromal cells has been observed during long-term expansion in cell culture, although it is rare. Engrafting these transformed cells into immunodeficient mice leads to the formation of solid tumors. Using high-throughput profiling methods, a panel of RNA molecules was identified as potential biomarkers for screening for these transformed cells in cell culture. (2014-01-29)

Test of maturity for stem cells
Stem cells can differentiate into 220 different types of body cell. The development of these cells can now be systematically observed and investigated with the aid of two new machines that imitate the conditions in the human body with unprecedented accuracy. (2008-05-06)

A fully human system to cultivate skin cells for grafting
Duke-NUS Medical School and the Singapore General Hospital have, for the first time, successfully cultured skin cells from human tissue-proteins to produce skin grafts for safer treatment of severe burns. The new technique could potentially replace the decades-old method of culturing skin grafts from combined human and animal biological material - the latter is considered high-risk under pharmaceutical GMP standards and the resulting 'xenografts' are limited to the treatment of severe burns or for compassionate use. (2018-10-31)

Peering into a more 'human' petri dish
The recent development of physiologic media, like other efforts designed to address the modeling capacity of cell culture, holds immense potential to improve understanding of human biology. (2019-11-04)

Embryonic stem cell culturing grows from art to science
A team of researchers at the University of Wisconsin-Madison reports the development of a fully defined culture system that promises a more uniform and, for cells destined for therapy, safer product. (2010-11-14)

New technique boosts potential for growing stem cells
A new method developed by University of Toronto researchers for growing specialized cells from embryonic stem cells could provide large numbers of these valuable cells for research and clinical purposes. (2002-05-27)

Hydrolyzed or non-hydrolyzed collagen: which one is suitable for nerve cell culture?
Hydrolyzed or non-hydrolyzed collagen: which one is suitable for nerve cell culture? (2013-09-05)

How dangerous are air pollutants really?
How severely do smog, diesel exhaust and secondhand smoke damage the lungs? What do pollen or nanoparticles trigger when they infiltrate the human body through inhaling? At this year's BIO Convention in Chicago from May 3-6, Fraunhofer researchers will present a new test system that can be used to investigate these questions. (2010-04-08)

New way to make human embryonic stem cell therapy safer
A new system for growing human embryonic stem cells could make therapies utilising the cells safer for patients, concludes a study published online by The Lancet (Tuesday, March 8, 2005). (2005-03-08)

New 3-D stem cell culture method published in JoVE
Stem cells are the body's mechanics, repairing damaged tissues and organs. Because these cells are able to grow into any type of cell in the body, scientists believe they hold the key to groundbreaking new therapies. To help further this research, scientists from the University of Victoria have found a new way to culture cells in 3-D -- a significant step forward for regenerative medicine. (2012-03-02)

Cell culture system could offer cancer breakthrough
A new cell culture system that provides a tool for preclinical cancer drug development and screening has been developed by researchers in the USA. The team, led by scientists from Princeton University, N.J., created a microfluidic cell culture device that allows the direct, real-time observation of the development of drug resistance in cancer cells. (2017-08-29)

Genomic analysis of pathogenic and benign gastritis bacteria
Infection with the mucosal resident bacterium Helicobacter pylori can lead to a series of diseases of the gut, culminating in some cases in gastric adenocarcinomas. Still, most long-term H. pylori carriers are apparently unharmed by the bacterium, either because of protective host genetic or environmental effects or because only a subset of H. pylori isolates are virulent. (2001-02-27)

Differences in CEO leadership style, company culture improve firm performance, study finds
Chief executive officers should have a different leadership style from an organization's culture in order to improve a firm's performance, according to researchers at Georgia State University, Arizona State University, the University of South Australia and Auckland University of Technology. (2016-07-13)

Long-term effects of embryo culture on behavior studied
According to scientists at the University of Pennsylvania, culturing mouse embryos under suboptimal conditions before implantation can effect how the offspring perform in behavioral assays that assess anxiety and memory. (2004-01-26)

A new paradigm for efficient upward culture of 3D multicellular spheroids
The 3D multicellular spheroids with intact cell-cell junctions are critical in biological research because they can mimic the cellular physiological environments. In this work, a durable superamphiphobic silica aerogel surface has been fabricated for the upward culture of 3D multicellular spheroids. Poly(3,4-ethylenedioxythiophene) was electrodeposited on a conductive steel mesh as a first template for porous silica coating. Soot particles were then applied as a second template to construct a cauliflower-like silica aerogel nanostructure. (2019-08-05)

Professor publishes on first-ever imaging of cells growing on spherical surfaces
The potential biomedical applications of the researchers' technique include new strategies and devices for the early detection and isolation of cancer cells, facilitating new methods of treating cancer tissues. (2012-09-21)

Neuronal cell cultures kept on the straight and narrow
An improved cell-culture technique developed at NIST uses microfluidics and some clever surface chemistry to culture difficult-to-grow neuron-like cells on a variety of surfaces, and to culture the cells in patterns to study the effects of geometry on cell development. The technique could enable new, fundamental insights into the behavior of the key cells of the central nervous system. (2006-05-25)

Cell removal technique could lead to cheaper drugs
Costly drugs to treat conditions such as cancer and arthritis could be manufactured more cheaply with a new technique developed by scientists. Researchers at the University of Edinburgh have pioneered a simple way to remove dead cells from cell cultures used to make protein-based drugs, which are increasingly prescribed to treat a range of illnesses. (2008-08-26)

From urine samples to precision medicine in bladder cancer through 3D cell culture
A research collaboration led by scientists from institutions in Japan including Tokyo University of Agriculture and Technology (TUAT) has developed a new experimental cancer model for dog bladder cancer. Urine samples were used for a 3D cell culture method called organoid culture. This method will allow us to quickly determine the proper chemotherapy and to identify new biomarkers of both dog and human bladder cancer in the near future. (2019-07-30)

3-D long-term bone marrow culture to analyze stromal cell biological function
In work published in the November 2011 issue of Experimental Biology and Medicine, Yukio Hirabayashi and co-investigators from Nihon University School of Medicine, Osaka Prefecture University and the Norwegian University of Science and Technology have developed a new three-dimensional bone marrow culture system. (2011-11-02)

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