Cirrhosis Current Events

Cirrhosis Current Events, Cirrhosis News Articles.
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Drinking coffee may reduce the risk of liver cirrhosis
Regular consumption of coffee was linked with a reduced risk of liver cirrhosis in a review of relevant studies published before July 2015. (2016-02-01)

Risk of liver cancer is low in patients with cirrhosis
Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is 4 percent or lower. (2017-02-01)

Overweight more harmful to the liver than alcohol in middle-aged men
Overweight carries a greatly increased risk of cirrhosis of the liver in men, reveals a new study from the Sahlgrenska Academy. (2011-06-07)

Cholesterol-lowering drugs may help patients with cirrhosis
Statins used for the treatment of high cholesterol may have other beneficial effects, but there has been reluctance to prescribe them to patients with liver disease because of concerns that they may cause abnormal liver enzyme levels in the blood. (2017-09-07)

Statins may benefit cirrhotic patients with hepatitis B or C infections
Infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to cirrhosis as well as liver cancer. A Hepatology study from Taiwan has found that statins may provide benefits to patients with HBV- or HCV-related cirrhosis. (2017-05-08)

Statins may benefit cirrhotic patients with Hepatitis B or C infections
Infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to cirrhosis as well as liver cancer. A Hepatology study from Taiwan has found that statins may provide benefits to patients with HBV- or HCV-related cirrhosis. (2017-04-24)

Liver diseases exhibit differing patterns in ethnic minorities
Chronic liver disease (CLD) and cirrhosis are serious liver conditions but little is known about how they affect ethnic minority populations in the United States. When researchers examined CLD and cirrhosis among different groups, they found that the prevalence of CLD ranged from 3.9 percent in African-Americans and Native Hawaiians to 4.1 percent in whites, 6.7 percent in Latinos, and 6.9 percent in Japanese. (2016-07-19)

New study finds continued abstinence is key to increased survival from alcohol-related liver disease
Providing you are still alive, it is never too late to stop drinking, even with the most severe case of alcohol-related liver disease, according to new research from the University of Southampton, published in the journal Addiction. (2009-04-20)

Serious liver-related condition on the rise in the US
A new analysis reveals that cirrhosis and acute on chronic liver failure (ACLF, a deterioration of liver function in patients with cirrhosis that results in the failure of one or more organs) represent a substantial and increasing health and economic burden in the United States. (2016-10-03)

Family of patients with NAFLD and cirrhosis are at increased risk of liver fibrosis
Non-alcoholic fatty liver disease can progress to cirrhosis and eventual liver disease. Family members of individuals diagnosed with non-alcoholic fatty liver disease are at a higher risk for developing the disease themselves. This week in the JCI, a clinical trial led by Rohit Loomba at UCSD reports that these family members are also at an elevated risk for liver fibrosis. (2017-06-19)

Liver cirrhosis more common than previously thought, study finds
Cirrhosis of the liver is more common than previously thought, affecting more than 633,000 adults yearly. And surprisingly, 69 percent of the adults identified as possibly having cirrhosis may not know they have the disease. (2015-01-05)

The economic cost of advanced liver disease
Health care costs for hepatitis C patients with end-stage liver disease are nearly 2.5 times higher than those in the early stages, according to a Henry Ford Hospital study. Although infection with the hepatitis C virus increases health care costs overall, the specific impact of the disease's progressive severity on health care costs has previously not been well studied. (2011-11-07)

Is cirrhosis associated with increased risk of stroke?
Cirrhosis was associated with increased risk of stroke, especially hemorrhagic, in a study that included a representative sample of more than 1.6 million Medicare beneficiaries, according to an article published by JAMA Neurology. (2017-06-05)

Innovation in science
Results of a study presented today at the at the International Liver Congress TM 2010 reveals the effects of a new drug for the treatment of primary biliary cirrhosis, and shows further evaluation is necessary. (2010-04-15)

Liver damage in hepatitis C patients significantly underestimated, says Henry Ford study
The number of hepatitis C patients suffering from advanced liver damage may be grossly underestimated and underdiagnosed, according to a study led by researchers at Henry Ford Health System and the US Centers for Disease Control and Prevention. The findings were the result of a study of nearly 10,000 patients suffering from hepatitis C, and could have a significant effect on patient care and healthcare policy regarding the chronic disease. (2015-08-18)

Women are not more likely to die of cirrhosis than men, despite fewer liver transplants
Prior studies suggested women might have higher mortality of cirrhosis of the liver than men. Women are also less likely to receive liver transplantation. But the research was unclear. A comprehensive new Northwestern Medicine study shows women are not more likely to die of liver cirrhosis than men, demonstrating that this liver disease affects men and women similarly. (2020-06-04)

Intestinal macrophages in liver cirrhosis produce NO, disrupt intestinal barrier function
A South African study presented today determines the importance of bacterial infections, which commonly occur in cirrhosis and can alter the natural history of the condition, possibly leading to loss of liver function and decompensation. It is now recognized that many infections in cirrhotic patients result from bacterial translocation from the intestine. (2012-04-19)

Heavy drinking endangers the health of liver transplants
Alcoholic liver disease is a major indication for liver transplantation, but up to 20 percent of patients experience severe alcoholic relapse. New research shows that such relapse can cause significant damage to newly transplanted livers. (2016-04-07)

Coffee drinking associated with lower risk for alcohol-related liver disease
Drinking coffee may be related to a reduced risk of developing the liver disease alcoholic cirrhosis, according to a report in the June 12 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. (2006-06-12)

Cell therapy trial offers new hope to liver disease patients
Researchers from the University of Edinburgh have received funding to start testing a new cell therapy to treat patients with liver disease. A clinical trial will begin within the next year. (2014-11-24)

Relative risks of cirrhosis from non-alcoholic steatohepatitis
According to a new study, cirrhosis related to non-alcoholic steatohepatitis (NASH) is associated with fewer complications and a lower mortality compared to cirrhosis from hepatitis C, despite NASH patients' greater risk of dying from cardiovascular events. (2006-04-03)

Gut microbes could help better predict risk of hospitalization for patients with cirrhosis
The gut microbiome -- a collection of bacteria and other microbes in the gut -- could be a highly accurate predictor of hospitalizations for patients with cirrhosis, according to a recently published study led by a researcher at Virginia Commonwealth University. (2018-03-30)

A South American amphibian could potentially hold the key in curing cirrhosis
The unique liver function of a South American amphibian, Siphonops annulatus, could pave the way to finding a cure to the devastating liver condition cirrhosis, a new study published in the prestigious Journal of Anatomy reports. (2017-12-06)

Cirrhosis deaths drop 41 percent from 2002 to 2012
A new study by University of North Carolina at Chapel Hill researchers has found dramatic improvements in the care of patients with cirrhosis and liver failure and recommends improved treatment strategies for patients with cirrhosis and concurrent bacterial infections. (2015-04-22)

Liver cirrhosis: Disease progression
Patients with liver cirrhosis display a wide range of clinical symptoms. A prospective study conducted by MedUni Vienna has now shown that blood levels of biomarkers for systemic inflammation increase over the various stages of the disease and can predict the development of complications, even in previously asymptomatic patients. (2020-11-30)

Vitamin D deficiency in cirrhosis
A research team from Denmark examined the vitamin D status in patients with alcoholic cirrhosis compared to those with primary biliary cirrhosis. They found that vitamin D deficiency in cirrhosis relates to liver dysfunction rather than etiology, with lower levels of vitamin D in alcoholic cirrhosis than in primary biliary cirrhosis. (2011-03-15)

Hard liquor, not beer or wine, may explain trends in cirrhosis mortality
Scientists have noted a new clue to an epidemiological mystery surrounding the link between alcohol and cirrhosis. Although cirrhosis has long been associated with heavy drinking, U.S. cirrhosis mortality trends have not always corresponded well with the nation's total alcohol consumption including beer, wine, and hard liquor. (1999-09-13)

Cirrhosis patients losing muscle mass have a higher death rate
Medical researchers at the University of Alberta reviewed the medical records of more than 100 patients who had a liver scarring condition and discovered those who were losing muscle were more apt to die while waiting for a liver transplant. These cirrhosis patients were placed at a lower spot on the transplant list because they had a higher functioning liver and were seemingly less sick than others with the same condition, based on scoring systems physicians commonly use today. (2012-02-07)

Antiviral therapies give Hepatitis C cirrhosis patients similar life expectancy as general population
The survival rate of patients with hepatitis C virus-related cirrhosis who respond well to antiviral therapies equals that of the general population, say investigators in the Journal of Hepatology. (2016-05-04)

Should we screen for cirrhosis?
Should we screen high risk patients for cirrhosis -- long-term liver damage that can eventually lead to liver failure? Experts debate the issue in The BMJ today. (2017-07-12)

Double the death rate from cirrhosis for 'blue collar' men
Australian manual or (2007-05-08)

Ledipasvir plus sofosbuvir: Hint of added benefit in further patient group
The documents subsequently submitted by the manufacturer show an advantage in sustained virologic response also for hepatitis C infection of genotype 1 with HIV coinfection without cirrhosis of the liver. (2015-05-22)

Research offers hope of new treatments for liver damage 'plague'
Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant. (2005-01-05)

Researchers find a promising new approach for treating liver cirrhosis
In a study in The American Journal of Pathology, investigators report that treatment with aleglitazar, a dual peroxisome proliferator-activated receptor-alpha/gamma (PPARα/γ) agonist, reduced inflammation, vasoconstriction, angiogenesis, mucosal disruption, and tumor necrosis factor (TNF)-α overproduction in cirrhotic rats with PH. This suggests a promising new approach for treating liver cirrhosis. (2018-06-18)

How does insulin-like growth factor I protect liver function?
A team led by Dra. Castilla de Cortázar Larrea from the University San Pablo-CEU has characterized some beneficial effects promoted by Insulin-like Growth Factor I (IGF-I) therapy on mitochondrial dysfunction associated to experimental cirrhosis, increasing the membrane potential and ATPase activity and reducing the intramitochondrial free radicals production and caspase-3 activity. (2008-05-07)

Increase in death rates from liver cirrhosis in Britain largest in western Europe
Britain has had the steepest increase in death rates from liver cirrhosis in western Europe since the 1950s, according to a study in this week's issue of The Lancet. (2006-01-05)

Research offers hope of new treatments for liver damage
Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. (2005-03-24)

Blood tests can predict the risk of liver cirrhosis
Repeated measurements of the biomarker FIB-4 in the blood every few years can predict the risk of developing severe liver disease, according to a new study from Karolinska Institutet in Sweden published in the Journal of Hepatology. The risk of liver cirrhosis increases if the levels of this biomarker rise between two testing occasions. (2020-07-02)

Mouth, as well as gut, could hold key to liver disease flare-ups
In a recent study, Virginia Commonwealth University School of Medicine researchers predicted which cirrhosis patients would suffer inflammations and require hospitalization by analyzing their saliva, revealing a new target for research into a disease that accounts for more than 30,000 deaths in the United States each year. (2015-04-17)

Daily drinking increases risk of alcoholic cirrhosis
Approximately 170,000 people die from alcoholic cirrhosis of the liver in Europe every year. Although alcohol is the most important risk factor, less is known about the significance of different patterns of drinking. Currently scientists believe that cirrhosis is a function of the volume of alcohol consumed irrespective of patterns of drinking. Investigators have now established that alcohol drinking pattern has a significant influence on the risk of cirrhosis and that daily drinking increases that risk compared with drinking less frequently. (2015-01-26)

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