Cord Blood Current Events

Cord Blood Current Events, Cord Blood News Articles.
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Institute of Medicine advisory: Cord blood stem cells
Stem cells from umbilical cord blood are used to treat a number of diseases, but the current system for collecting, storing, and allocating donated cord blood is fragmented and less efficient than it could be. (2005-04-12)

NHS should not encourage commercial blood banking
NHS maternity units should not encourage commercial banking of umbilical cord blood, argues a senior doctor in this week's BMJ. (2006-10-13)

Sibling Cord Blood May Offer Best Match Chance For Some Patients
Children needing bone marrow transplants may find their best chance in umbilical cord blood from a sibling, even if the transplant is only partially matched to the recipient's blood type, according to Duke researchers. (1998-12-04)

Umbilical cord blood banking Richard Branson's way
Any attempt to increase the available pool of umbilical cord blood cells, which are otherwise just discarded, should be enthusiastically praised, states the lead editorial in this week's issue of the Lancet. (2007-02-08)

Cord blood for stem cell transplant may outperform matched sibling donor
Study based on a decade of research and treatment shows no difference in overall survival between cord blood and matched related donor as source for stem cell transplant, with reduced graft-versus-host disease in patients using cord blood. (2020-06-05)

Potential target for restoring ejaculation in men with spinal cord injuries or ejaculatory disorders
New research provides insights on how to restore the ability to ejaculate in men who are not able to do so. (2016-12-05)

ViaCell Inc., the world's largest umbilical cord blood research and banking company comments on Bush administration's decision
ViaCell, Inc., a fully-integrated cellular therapy company committed to enabling the development of additional therapeutic applications for umbilical cord blood stem cells, commended the Bush Administration's decision to support additional funding for alternative sources of stem cells. Umbilical cord blood is considered an attractive alternative source and is an abundant and non-controversial store of neonatal stem cells.ViaCell has pioneered a platform technology, Selective Amplification™, that enables the expansion of the umbilical cord blood stem cell population. (2001-08-10)

Super-potent blood stem cells discovered in human embryos
In research recently published in Stem Cell Reports, Andrejs Ivanovs, Alexander Medvinsky (a.medvinsky@ed.ac.uk) and colleagues from the University of Edinburgh discovered that HSCs from early human embryos, when HSCs are just starting to form, are more robust at expanding than those from the cord blood. (2020-09-17)

Umbilical Cord Blood Transplantation - Statement From Claude Lenfant, M.D., Director, National Heart, Lung, And Blood Institute
A study in the November 26 New England Journal of Medicine shows that cord blood transplantation is a feasible procedure for patients who do not have a related matching donor. It also confirms earlier findings that the procedure works in children even if there is not a complete HLA match. (1998-11-25)

U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells. (2006-02-13)

Phase I Trial Promising For Cord Blood Transplant "Booster"
Adding a dose of slightly more mature stem cells to an umbilical cord blood transplant shows promise for increasing the success of transplants in children, Duke researchers reported Friday. (1998-12-04)

Are dual cord blood banks the answer to increasing stem cell demand?
Demand for stem cells from cord blood is greater than supply. In this week's BMJ, two senior doctors, Professors Nicholas Fisk and Rifat Atun, analyze the UK's growing cord blood banking industry and the potential impact of a new bank that provides blood for both personal and public use. (2008-03-20)

13 lifelines successfully used in unique umbilical cord blood transplant into ailing adult
CorCell, one of the nation's foremost umbilical cord blood banking facilities, located in Philadelphia, has successfully completed one of the first transplants of 13 separately donated umbilical cord blood collections into one 350 lb. adult patient suffering from Acute Myelogenous Leukemia. (1999-08-17)

Umbilical cord blood not suitable for assessing allergy risk
For years, hospitals and researchers have been testing blood samples from the umbilical cords of newborn babies to assess the risk of allergy. Now a study at the University of Copenhagen has revealed that the biomarker in the blood that indicates the risk factor for allergy often comes from the mother rather than her baby. (2010-10-05)

Umbilical cord blood transplant: effective new leukemia treatment for adults
In the first published study of its kind, researchers at the Ireland Cancer Center, University Hospitals of Cleveland and Case Western Reserve University demonstrate successful use of umbilical cord blood transplantation in adults with leukemia and other blood disorders. (2001-06-12)

Unrelated umbilical cord blood transplants could boost treatment options for children with leukemia
The five-year leukemia-free survival rates in children are similar following either allele-matched bone-marrow transplants or transplants of umbilical cord blood mismatched for either one or two human leucocyte antigens. These findings, reported in an article in this week's edition of The Lancet, could increase the treatment options available for children with leukemia for whom a bone-marrow donor match cannot be found. (2007-06-07)

New 'more effective' stem cell transplant method could aid blood cancer patients
Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults. (2020-03-26)

Umbilical cord clamping should be delayed, says expert
Clamping and cutting of the umbilical cord should be delayed for three minutes after birth, particularly for preterm infants, suggests a senior doctor in this week's BMJ. (2007-08-16)

Neuroprotective mechanisms of gene and cell therapy of spinal cord injuries
Genetically modified stem and progenitor cells overexpressing NTFs have recently attracted special attention of researchers and are most promising for the purposes of regenerative medicine. Therefore, we have studied the effect of genetically modified human umbilical cord blood mononuclear cells on the expression of stem cell molecular determinants in spinal cord injuries. (2018-03-06)

Spinal cord injury affects the heart
Spinal cord injury affects the heart, that's what research published in Experimental Physiology and carried out by researchers from University of British Columbia, Canada has found. (2017-12-12)

Cord blood bank at M. D. Anderson Cancer Center receives $9 million grant
In a move that could dramatically increase the nation's supply of stem cells for transplantation, the Health Resources and Services Administration (HRSA), part of the U. S. Department of Health and Human Services, recently awarded a $9 million grant to the cord blood bank at The University of Texas M. D. Anderson Cancer Center. The three-year grant will fund the collection, processing and storage of umbilical cord blood at M. D. Anderson to be entered in the National Cord Blood Inventory (NBCI). (2007-02-22)

Delayed cord clamping
Should you clamp the umbilical cord within a minute of birth or wait two or three minutes? A Cochrane Systematic Review considered data from 11 trials that included a total of 2,989 mothers and their babies, and concluded that early or late clamping caused no differences for the mother in terms of greater risk of blood loss. (2008-04-15)

Intranasal nerve growth factor repairs injured spinal cord neurons
Nerve growth factor can be delivered to the brain by intranasal administration without risk for treatment of brain diseases. Dr. Luigi Aloe, Cellular Biology and Neurobiology Institute, National Research Council, Italy and his team performed a study to investigate whether, by intranasal administration, the nerve growth factor bypasses the blood-brain barrier and turns over the spinal cord neurons. (2014-07-17)

NHLBI Cord Blood Transplantation Study Begins
The first multicenter study of umbilical cord blood transplants from unrelated, newborn donors was announced by the National Heart, Lung, and Blood Institute of the National Institutes of Health (1996-10-07)

Research could change how blood pressure is managed in spinal cord injury patients
New research from the International Collaboration on Repair Discoveries (ICORD) challenges the current standard for managing blood pressure in people with spinal cord injury (SCI). (2020-10-15)

Placenta removal -- a safer method after Caesareans
In Caesarean deliveries the placenta is usually removed by hand or by a technique known as 'cord traction'. A recent systematic review by Cochrane researchers shows that cord traction poses less risk to the mother than manual removal. (2008-07-15)

Getting more mileage out of cord blood
Blood from human umbilical cords is rich in stem cells and decreases the risk of transplant rejection. However, the amount of blood cells collected from cords is often not sufficient for an adult recipient. Irwin Bernstein and colleagues at the Fred Hutchinson Cancer Research Center, Seattle exposed cord blood to a molecule called Delta-1, expanding stem cell numbers 100-fold. These cells were also more potent in reconstituting the immune response following transplantation into mice. (2002-10-22)

Transient Maternal Cell Growth In Cord Blood Recipients Can Be Treated
Mothers' cells may begin to grow and form bone marrow in children receiving umbilical cord blood transplants, but any resulting rejection problems can be dealt with, researchers from Duke University Medical Center said. (1998-12-07)

University of Colorado gets federal award for Cord Blood Bank
University of Colorado Cord Blood Bank wins a $6.3 million award to collect umbilical cord blood with an emphasis on minority donors. (2010-10-06)

Don't clamp umbilical cords straight after birth, urges expert
Obstetricians and midwives should wait a few minutes before clamping the umbilical cords of newborn infants so that babies are not harmed by the procedure, argues Dr. David Hutchon in an article published online today. (2010-11-10)

Prenatal testosterone linked to increased risk of language delay for male infants, study shows
New research by Australian scientists reveals that males who are exposed to high levels of testosterone before birth are twice as likely to experience delays in language development compared to females. The research, published in Journal of Child Psychology and Psychiatry, focused on umbilical cord blood to explore the presence of testosterone when the language-related regions of a fetus' brain are undergoing a critical period of growth. (2012-01-25)

Nation's public cord blood banks provide benefits, despite drop in use, study finds
More than a decade ago the federal government helped support the creation of public umbilical cord banks to collect and store a genetically diverse set of stem cells for clinical care and research. While use of stem cells from the banks has been dropping, the system still deserves support and can be bolstered in several ways to improve its usefulness, according to a new study. (2017-09-29)

Low umbilical cord pH at birth linked to death and brain damage
Low umbilical cord blood pH at birth is strongly associated with serious outcomes such as infant death, brain damage and the development of cerebral palsy in childhood, concludes a study published on bmj.com today. (2010-05-13)

Altering present criteria for matching donors and recipients could improve transplant survival
Selecting better matched recipients and donors than is currently required for umbilical-cord blood transplantation could substantially reduce transplant-related deaths. The findings, published Online First in The Lancet Oncology should change standard practice for cord-blood donor selection. (2011-10-06)

Study reveals potential for more efficient stem cell transplants
An Indiana University School of Medicine study suggests that stem cells found in bone marrow, umbilical cord blood and some adult blood products can be enhanced in trafficking to the bone marrow and may increase transplant success, particularly in adults. (2004-08-13)

Spinal cord processes information just like areas of the brain
Patrick Stroman's work mapping the function and information processing of the spinal cord could improve treatment for spinal cord injuries. (2011-03-22)

Research shows cord blood comparable to matched bone marrow
University of Minnesota researchers report that umbilical cord blood transplants may offer blood cancer patients better outcomes than bone marrow transplants, according to an analysis of outcome data performed at the Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee. (2007-06-07)

Later cord clamping after birth increases iron levels in babies
Delaying clamping of the umbilical cord after birth benefits newborn babies, according to a systematic review published in The Cochrane Library. The authors found babies' blood and iron levels were healthier when the cord was clamped later. (2013-07-10)

Clinical study results using Aldagen's product to isolate cord blood stem cells presented at ASH
Interim data from a clinical trial using Aldagen's product, ALDESORT to isolate stem cells from cord blood was presented at the 48th Annual Meeting of the American Society of Hematology demonstrating improved safety and efficacy when using ALDESORT compared to the COBLT control group. The trial is being conducted by Joanne Kurtzberg, M.D., the Duke University physician who pioneered the use of umbilical cord blood as treatment for fatal childhood cancers and genetic diseases. (2006-12-11)

Private umbilical cord banking not cost-effective, UCSF research shows
Private cord blood banking is not cost-effective because it costs an additional $1,374,246 per life-year gained, according to a new analysis by UCSF researchers. The research team also concluded that private cord blood banking is cost-effective only for families with a child with a very high likelihood of needing a stem cell transplant. (2009-09-22)

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