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Cytokines Current Events, Cytokines News Articles.
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Researchers discover how 'promiscuous parasites' hijack host immune cells
Cornell researchers recently discovered how T. gondii evades our defenses by hacking immune cells, making it the first known parasite to control its host's immune system. Immunologists from the College of Veterinary Medicine published the study Sept. 8 in PLoS Pathogens, describing a forced partnership between parasite and host that challenges common conceptions of how pathogens interact with the body. (2011-09-21)

Novel microfluidic HIV test is quick and cheap
UC Davis biomedical engineer Alexander Revzin has developed a (2010-07-16)

Avoiding fatal responses to flu infection
Most of the time, being ill with the flu is little more than a nuisance. Other times, it can spark an exaggerated immune response and turn deadly. Researchers reporting in the Sept. 16 issue of the journal Cell, a Cell Press publication, have now traced the origins of this severe immune response -- called a cytokine storm -- to its source. (2011-09-15)

Symptoms of depression may worsen heart failure
New research suggests that depression may hasten the progression of heart disease by increasing the levels of a key protein that causes inflammation. In a study of 32 people with heart failure, the 14 patients who felt the most depressed had nearly twice the levels of this protein in their blood. (2005-09-07)

Increased levels of certain cytokines and chemokines predict onset of rheumatoid arthritis
Up-regulation of certain cytokines and chemokines (signaling molecules involved in the functioning of the immune system) can predict the development of rheumatoid arthritis three years before the onset of symptoms, according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. (2009-06-13)

Fish oil and vitamin E reduce levels of pro-inflammatory proteins in rheumatoid arthritis, UB study shows
A study by University at Buffalo researchers has shown that fish oil and vitamin E are promising potential therapies for those suffering from rheumatoid arthritis. (2000-10-30)

Antibodies attack immune proteins
Two studies published online on Feb. 1 in the Journal of Experimental Medicine reveal that patients with a rare autoimmune disease produce antibodies that attack microbe-fighting immune proteins called cytokines. These findings may help explain why these patients suffer recurrent yeast infections. (2010-02-01)

Role Of Cytokines In Treating Heart Disease Unveiled By Penn Scientists
University of Pennsylvania Medical Center researchers are investigating the role of cytokines in explaining the effectiveness of amlodipine, a widely prescribed calcium- channel blocker for patients with heart failure. A better understanding of the relationship between cytokines and amlodipine is hoped to lead to more effective therapies for heart failure. (1997-08-26)

Gene discovery unlocks mysteries to our immunity
Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease. (2018-07-01)

New anti-inflammatory molecule could halt MS progression
Walter and Eliza Hall Institute scientists have developed a new drug-like molecule that can halt inflammation and has shown promise in preventing the progression of multiple sclerosis. Dr. Ueli Nachbur, associate professor John Silke, associate professor Guillaume Lessene, professor Andrew Lew and colleagues developed the molecule inhibit a key signal that triggers inflammation. (2015-03-17)

Cytokine signal shuts down hyperactive T cells
Unlike similar proteins, cytokine IL-27, may actually suppress CD4+ T cells, the 'helper' T cells that orchestrate the immune system's response to infections. Findings from University of Pennsylvania School of Veterinary Medicine researchers could lead to a means to clamp down on dozens of autoimmune conditions. (2003-11-25)

Ending the perfect storm: Protein key to beating flu pandemics
A protein called SOCS4 has been shown to act as a handbrake on the immune system's runaway reaction to flu infection, providing a possible means of minimizing the impact of flu pandemics. (2014-05-08)

Do cytokines have a role in the initiation and progression of breast cancer?
Emerging data on the role of inflammation and the immune system in the development, growth, and spread of breast tumors have focused increased attention on the role cytokines such as interleukin and transforming growth factor-β play in breast cancer initiation, protection, and metastasis. A comprehensive overview of this new knowledge and its potential to lead to novel therapeutic approaches is presented in a Review article in Journal of Interferon & Cytokine Research. (2015-01-13)

Common cholesterol drug prevents, reverses MS symptoms in mice
Lipitor ™, the most frequently used cholesterol lowering agent in the world, proved effective in reversing paralysis in a mouse model of multiple sclerosis. (2002-04-20)

Cornell bioengineers discover the natural switch that controls spread of breast cancer cells
With a desire to inhibit metastasis, Cornell biomedical engineers have found the natural switch between the body's inflammatory response and how malignant breast cancer cells use the bloodstream to spread. (PLOS ONE, Jan. 23, 2013) (2013-01-23)

New technique may quickly distinguish between active and latent TB
An emerging technique designed to quickly distinguish between people with active and dormant tuberculosis may help health professionals diagnose the disease sooner, thereby potentially limiting early exposure to the disease, according to a study conducted by researchers at Duke University Medical Center. (2010-05-16)

High levels of immune protein in infant brain linked to SIDS
High levels of a protein called cytokine in the brains of infants could hold a clue to the cause of Sudden Infant Death Syndrome (SIDS), according to a study in the November 11 issue of Neurology, the scientific journal of the American Academy of Neurology. (2003-11-10)

Binge drinkers let down guard against infection
As if a bad hangover wasn't enough of a deterrent, new research has shown how binge drinking weakens the body's ability to fight off infection for at least 24 hours afterwards. The study, published today in the open access journal BMC Immunology, focused on the effect of heavy drinking on toll-like receptor 4, a protein that has an important role in immune system activation. (2009-09-17)

GM-CSF required for the immune attack in multiple sclerosis
The neutralization of the cytokine GM-CSF could halt the development of multiple sclerosis. This was demonstrated by the research team of the immunologist Burkhard Becher at the University of Zurich in an animal model. Unlike other known cytokines, they write in the journal Nature Immunology, this messenger substance is essential for the development of the disease. By the end of this year, a clinical trial will be launched in which GM-CSF is to be neutralized in MS patients. (2011-04-24)

Poor sleep in pregnancy can disrupt the immune system and cause birth-related complications
Poor sleep quality and quantity during pregnancy can disrupt normal immune processes and lead to lower birth weights and other complications, finds a University of Pittsburgh School of Medicine study published today in the journal Psychosomatic Medicine. Women with depression also are more likely than non-depressed women to suffer from disturbed sleep and to experience immune system disruption and adverse pregnancy outcomes. (2013-07-17)

Study suggests antibiotic may limit or prevent vision problems caused by diabetes
A Penn State College of Medicine study suggests that a common antibiotic called minocycline may slow or prevent diabetic retinopathy, a complication of diabetes that is the leading cause of blindness in people ages 20 to 74. (2005-05-10)

Scientists discover how rogue communications between cells lead to leukemia
New research has deciphered how rogue communications in blood stem cells can cause leukemia. The discovery could pave the way for new, targeted medical treatments that block this process. (2020-02-06)

Optimizing antiviral peptide vaccines
Costimulatory receptors on T cell surface modulate the signaling pathways that activate lymphocytes against specific antigens, often with profound effects on the ultimate host response. Ahlers et al. have followed the immune cell interactions that lead to the development of antiviral immunity in animals vaccinated with an HIV peptide. (2001-11-28)

Team studies immune response of Asian elephants infected with a human disease
Mycobacterium tuberculosis, the organism that causes tuberculosis in humans, also afflicts Asian -- and occasionally other -- elephants. Diagnosing and treating elephants with TB is a challenge, however, as little is known about how their immune systems respond to the infection. A new study begins to address this knowledge gap, and offers new tools for detecting and monitoring TB in captive elephants. (2014-07-15)

Stress linked to more advanced disease in some leukemia patients
Patients with chronic lymphocytic leukemia (CLL) who feel more stress also have more cancer cells in their blood and elevated levels of three other markers of more advanced disease. (2018-09-11)

Negative regulator stops extreme immune response to parasite, averting multi-organ damage
A new study from Osaka University identified a role for the BATF2 protein in negatively regulating the immune response to infection by the protozoan parasite Trypanosoma cruzi, which is responsible for Chagas disease. BATF2 was shown to inhibit production of the IL-23 cytokine, thus limiting immunopathology mediated by another cytokine, IL-17. This furthers understanding of the host response to parasitic infection, and is likely to be applicable to other immune disorders. (2017-04-03)

What role do cytokines play in autoimmune diseases?
Cytokines, a varied group of signaling chemicals in the body, have been described as the software that runs the immune system, but when that software malfunctions, dysregulation of the immune system can result in debilitating autoimmune diseases such as lupus, arthritis, and diabetes. (2011-10-27)

Study by UCSD gives new insight into how anthrax bacteria can evade a host's immune response
Biologists at the University of California, San Diego have determined how toxin produced by anthrax bacteria blocks a person's normal immune response, a discovery that could lead to new treatments for anthrax infection. (2004-01-06)

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant...
Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system. Comparing NSCLC PE and published plasma levels of CAR-T recipients, both were dominated by sIL-6R and IL-6 but NSCLC PE had more VEGF, FGF2 and TNF, and less IL-2, IL-4, IL-13, IL-15, MIP1 and IFN. (2019-11-22)

Compound found in red wine causes conflicting changes in dogs' immune systems
Researchers at the University of Missouri have found that resveratrol does affect the immune systems of dogs in different ways when introduced to dogs' blood. (2015-08-24)

How does the immune system fight off threats to the brain? New research yields fresh insight
Like a police officer calling for backup while also keeping a strong hold on a suspected criminal, immune cells in the brain take a two-tier approach to fighting off a threat, new research shows. For the first time, scientists have captured that reaction in action, showing how certain immune cells locked onto a model of virus-infected brain cells, while also sending signals to neighboring uninfected cells to let them know about the immune attack. (2012-04-30)

Compound in celery, peppers reduces age-related memory deficits
A diet rich in the plant compound luteolin reduces age-related inflammation in the brain and related memory deficits by directly inhibiting the release of inflammatory molecules in the brain, researchers report. (2010-10-13)

Bad to the bone: some breast cancer cells are primed to thrive
Howard Hughes Medical Institute researchers have discovered that some breast cancer cells bear a distinct (2013-08-29)

Cytokine implicated in HLH treatment resistance
Research sheds light on cytokine storm syndromes and how ruxolitinib may benefit patients with hemophagocytic lymphohistiocytosis. (2020-06-12)

New Study By TSRI Scientists Sheds Light On Viral Clearance In Acute Hepatitis B Infection
A study published this week by scientists at The Scripps Research Institute demonstrates a new paradigm in viral immunology, that the immune system can cure viral infections without destroying the infected cells. They conclude that nondestructive antiviral mechanisms can contribute to viral clearance by eliminating a virus from inside the cell without killing it. (1999-04-30)

Environmental factors instruct lineage choice of blood progenitor cells
The research team led by Dr. Timm Schroeder, stem cell researcher at Helmholtz Zentrum Muenchen, has developed a new bioimaging method for observing the differentiation of hematopoietic progenitor cells (HPC) at the single-cell level. With this method the researchers were able to prove for the first time that not only cell-intrinsic mechanisms, but also external environmental factors such as growth factors can control HPC lineage choice directly. (2009-07-15)

Link between immune system and mammary gland could shed new light on breast cancer
Scientists at the University of Cambridge have published new research today (July 5) in the journal Development showing an unexpected link between a fundamental part of the immune system and the cells that produce milk in the breast during lactation. (2007-07-04)

Researchers develop better understanding of immune response to viral infection
An appropriate response by the immune system to viral infection is absolutely critical for survival. A new research study published in the July issue of Immunity sheds light on the complex and well-orchestrated signals that are mobilized in response to infection with cytomegalovirus. (2004-07-20)

What foods can help fight the risk of chronic inflammation?
A new study by the University of Liverpool's Institute of Ageing and Chronic Disease has identified food stuffs that can help prevent chronic inflammation that contributes to many leading causes of death. (2016-05-16)

Cancer commandeers immature immune cells to aid its successful spread
More typically, these immature immune cells might help us fight cancer, but scientists have now shown cancer can commandeer the cells to help it spread. (2017-04-06)

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