Dengue Virus Current Events

Dengue Virus Current Events, Dengue Virus News Articles.
Sort By: Most Viewed | Most Recent
Page 1 of 25 | 1000 Results
Genome circularization and RNA virus replication
As featured on the cover of the August 15 issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication. (2006-07-31)

Molecular aspects of the dengue virus infection process: A review
At the present time, dengue is one of the most important arboviruses affecting man, becoming a serious global public health problem, especially in subtropical and tropical countries, where environmental conditions favor the development and proliferation of the mosquito Aedes aegypti. Dengue is caused by a type of flavivírus, which is an enveloped virus of spherical geometry. (2019-01-13)

Plotting the elimination of dengue
Researchers at the University of Melbourne along with international collaborators are using a novel way to block the dengue virus in Aedes aegypti mosquitoes using the insect bacterium, Wolbachia and have for the first time provided projections of its public health benefit. (2015-04-08)

Dengue 'Achilles heel' insight offers hope for better vaccines
Researchers have new insights into how protective antibodies attack dengue viruses, which could lead to more effective dengue fever vaccines and drug therapies. The University of Queensland and China's ZhuJiang Hospital collaboratively led the study which identified an antibody that binds to, and kills, all four types of dengue virus. (2017-12-18)

NUS scientists discover novel vulnerabilities in dengue virus
A team of researchers from the National University of Singapore has uncovered hidden vulnerabilities on the surface of the dengue virus. (2017-03-30)

Previous exposure to flaviviruses increases effects of Zika
Prior infection with dengue or West Nile virus can enhance the effects of Zika infection, a new study using human samples tested in mice finds. (2017-03-30)

T cell-inducing dengue vaccines may better protect children of vaccinated mothers
Although maternal antibodies help to protect babies against dengue virus infection, they can also be detrimental. In some situations, maternal antibodies can enhance the severity of dengue infections in babies or interfere with immunization of the babies. NUS Medicine researchers have now shown that, in the face of such complications, a dengue vaccine that provokes a strong killer T cell response in these children can provide better and broader protection than vaccines inducing mainly antibodies. (2017-12-22)

Human challenge promises to speed up dengue vaccine development
A controlled human challenge study shows that a candidate dengue vaccine can fully protect healthy volunteers who were intentionally infected with a weak form of the dengue virus. (2016-03-16)

Long-term study of Nicaraguan children reveals key window in which...
Adding proof to a longstanding but previously unconfirmed theory about severe dengue in humans, a new study in children from Nicaragua pinpoints a narrow but critical range of antibody level that enhances reaction to the disease the second time around. (2017-11-02)

New understanding of dengue fever could help with vaccine
Some of the human immune system's defences against the virus that causes dengue fever actually help the virus to infect more cells, according to new research published today in the journal Science. The researchers behind the work, from Imperial College London, hope their new findings could help with the design of a vaccine against the dengue virus. (2010-05-06)

Antibodies that are effective against both dengue and Zika viruses
Scientists from the Institut Pasteur and the CNRS, in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal vaccine that offers simultaneous protection against dengue and Zika virus disease. (2016-06-23)

The sting in dengue's tail
In a new Science study, Duke-NUS Graduate Medical School Singapore scientists have identified how small changes in dengue's viral genome can affect the virus' ability to manipulate human immune defenses and spread more efficiently. (2015-07-02)

Human antibody blocks dengue virus in mice
Researchers have discovered that a human antibody specific to dengue virus serotype 2, called 2D22, protects mice from a lethal form of the virus -- and they suggest that the site where 2D22 binds to the virus could represent a potential vaccine target. (2015-07-02)

Structure of Zika virus revealed
A new study reveals the structure of the Zika virus, shedding light on its similarities and differences compared to viruses of the same family. (2016-03-31)

Fast and accurate 'dipstick' test for diagnosing Zika
A newly developed, fast, and cost-effective dipstick test sensitively and specifically identified Zika virus and all four dengue virus subtypes without any detectable cross-reactivity. (2017-09-27)

Going viral: Insights on Zika
Understanding the full history the Zika virus along with new developments is key to getting a vaccine and medicine to prevent and relieve Zika infections. This includes knowing all the transmission methods -- it's more than a mosquito bite. (2016-10-13)

Zika antibodies from infected patient thwart infection in mice
Researchers have identified neutralizing antibodies against Zika virus from an infected patient that fully protected mice from infection, adding to the current arsenal of antibodies in development for much needed antiviral therapies and vaccines. (2016-12-14)

Powerful dengue neutralizing antibody found
A new Duke-NUS-led study has identified a super-potent antibody which requires a minute amount to neutralize the dengue virus. The study, published in the journal Nature Communications, showed how a newly identified antibody 5J7, is highly effective in killing dengue virus whereby only 10-9 g of antibody is needed to stop the infection of dengue serotype 3 virus. This new finding gives hope for the development of effective dengue treatments. (2015-02-20)

One step closer to a DNA vaccine against dengue virus
In a new study, researchers inoculated mice with a new DNA vaccine candidate (pVAX1-D1ME) in order to evaluate its efficiency. They found that the vaccine candidate was able to induce persistent humoral and cellular immune responses and provided efficient protection against lethal challenge from one of the four serotypes of dengue virus (DV1). These results are encouraging for the future development of a tetravalent vaccine that could provide efficient protection against all four serotypes of the virus. (2017-06-29)

Study defines level of dengue virus needed for transmission
Researchers have identified the dose of dengue virus in human blood that is required to infect mosquitoes when they bite. Mosquitoes are essential for transmitting the virus between people so the findings have important implications for understanding how to slow the spread of the disease. (2013-05-13)

T cell responses may help dodge dengue virus symptoms during infection
Scientists now have new insight into the immune responses that prevent people infected with dengue virus from experiencing clinical symptoms, which could help optimize ongoing vaccine development efforts. (2017-08-30)

Dengue virus turns on mosquito genes that make them hungrier
Researchers at the Johns Hopkins Bloomberg School of Public Health have, for the first time, shown that infection with dengue virus turns on mosquito genes that makes them hungrier and better feeders, and therefore possibly more likely to spread the disease to humans. Specifically, they found that dengue virus infection of the mosquito's salivary gland triggered a response that involved genes of the insect's immune system, feeding behavior and the mosquito's ability to sense odors. (2012-03-29)

Zika virus: 5 things to know
A concise 'Five things to know about.... Zika virus infection' article for physicians highlights key points about this newly emerged virus in CMAJ (Canadian Medical Association Journal). (2016-02-08)

Researchers identify Achilles heel of dengue virus, target for future vaccines
This study for the first time shows what dengue virus region the immune system of humans target when they are fighting off the virus. (2012-04-11)

Decoding dengue
Scientists have discovered a new pathway the dengue virus takes to suppress the human immune system. This new knowledge deepens our understanding of the virus and could contribute to the development of more effective therapeutics. (2014-07-16)

Mother's dengue immunity worsens baby's response to Zika
New research uncovers previously unknown mechanism behind why some, but not all, Zika virus infections during pregnancy lead to fetal brain abnormalities. (2019-02-28)

Breakthrough on curbing dengue
Scientists from Australia's national science agency, CSIRO, and the University of California San Diego have engineered the first breed of genetically modified mosquitoes resistant to spreading all four types of the dengue virus. (2020-01-16)

Vanderbilt research could lead to vaccines and treatment for dengue virus
Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus. (2015-07-02)

UQ scientists close in on first dengue treatment
Clinical trials for a dengue fever treatment could start within a year, following a discovery by University of Queensland scientists. UQ's School of Chemistry and Molecular Biosciences Head Professor Paul Young said the researchers had identified similarities in how the body reacted to dengue virus and bacterial infections, in a finding that would allow them to repurpose existing drugs. (2015-09-09)

UTMB researchers have discovered a new antiviral mechanism for dengue therapeutics
A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences. (2020-07-13)

Research points to possible new route to fight dengue virus
Researchers have identified enzymes and biochemical compounds called lipids that are targeted and modified by the dengue virus during infection, suggesting a potential new approach to control the aggressive mosquito-borne pathogen. Findings also suggest that medications used to treat high cholesterol and other lipid-related conditions might also inhibit dengue's replication and could represent a potential new therapy. The researchers have identified how infected mosquito cells undergo changes to certain lipids in membranes and in biochemical sensors that alert cells of invading viruses. (2012-03-22)

Prior dengue or yellow fever exposure does not worsen zika infection in monkeys
Rhesus macaques previously infected with dengue or yellow fever viruses appear to be neither more nor less susceptible to severe infection with Zika virus, according to new research published in PLOS Pathogens. (2017-08-04)

Rethinking the antibody-dependent enhancement dengue hemorrhagic fever model
Research published this week in PLoS Medicine challenges the dogma of the antibody-dependent enhancement model for the development of dengue hemorrhagic fever. (2009-10-26)

Zika virus tested in brain precursor cells
Zika virus preferentially kills developing brain cells, a new study reports. The results offer evidence for how Zika virus may cause brain defects in babies -- and specifically microcephaly, a rare birth defect in which the brain fails to grow properly. (2016-04-11)

Report suggests nearly 5 percent exposed to dengue virus in Key West
An estimated 5 percent of the Key West, Fla., population -- over 1,000 people -- showed evidence of recent exposure to dengue virus in 2009, according to a report from the Centers for Disease Control and Prevention and the Florida Department of Health. (2010-07-13)

New approach holds promise for dengue fever
Monash University and 60P Australia Pty Ltd, a subsidiary of 60° Pharmaceuticals LLC, have announced today an exclusive partnering deal, with 60P obtaining rights to develop the drug Fenretinide for dengue fever. (2014-12-01)

Vermont Vaccine Testing Center study reveals effective, single-dose dengue vaccine
Results from a dengue vaccine virus challenge study show 100 percent protection in clinical trial participants tested at University of Vermont and Johns Hopkins University. (2016-03-16)

Found: Antibody that zaps resilient dengue serotype
A research team led by the Duke-NUS Graduate Medical School Singapore has found the second-to-last piece of the puzzle needed to potentially cure or treat dengue. This is welcome news as the dengue virus infects about 400 million people worldwide annually, and there is currently no licensed vaccine available to treat it. (2015-07-02)

Dengue virus becoming resistant to vaccines and therapeutics due to mutations in specific protein
Researchers from Duke-NUS Medical School, in collaboration with the Agency for Science, Technology and Research's Bioinformatics Institute, and the University of Texas Medical Branch, USA, have discovered that the dengue virus changes its shape through mutations in Envelope protein to evade vaccines and therapeutics. The study also gives insights on the types of treatment strategies to use at different stages of infection. This could give rise to new approaches in vaccine development and treatment for dengue disease. (2019-09-20)

Dengue: Asymptomatic people transmit the virus to mosquitoes
Scientists at the Institut Pasteur in Cambodia, the Institut Pasteur in Paris and the CNRS provided proof that people infected by dengue virus but showing no clinical symptoms can actually infect mosquitoes that bite them. It appears that these asymptomatic people -- who, together with mildly symptomatic patients, represent three-quarters of all dengue infections -- could be involved in the transmission chain of the virus. (2015-11-10)

Page 1 of 25 | 1000 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.