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Disease Therapy Current Events, Disease Therapy News Articles.
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Emerging Alzheimer's disease therapies: Focusing on the future
On November 7, 2001, world leaders in Alzheimer's Disease research will converge on the University of Pennsylvania Medical Center to discuss the future of Alzheimer's therapy. The retreat, organized by John Q. Trojanowski, MD, PhD, and Virginia M. -Y. Lee, PhD, co-founders and co-directors of the Penn Center for Neurodegenerative Disease Research (CNDR), is free and open to students, researchers, clinicians, and interested members of the press. (2001-09-27)

Thomas Kipps receives ACGT Investigator Award
Citing his on-going development of an immune-mediated gene therapy for intractable B cell leukemia, the Alliance for Cancer Gene Therapy (ACGT) has awarded Thomas J. Kipps, MD, PhD, professor of medicine in the University of California, San Diego School of Medicine and deputy director of research operations at the UC San Diego Moores Cancer Center, its 2010 Investigator Award in Clinical Translation of Cell and Gene Therapy. (2011-04-20)

Neoadjuvant and adjuvant systemic therapy for breast cancer give equivalent survival, study finds
The timing of systemic therapy--chemotherapy or endocrine therapy--for breast cancer does not appear to affect survival or disease progression. However, women who receive systemic therapy and radiation therapy without surgery may be more likely to experience a recurrence of their cancer compared with women treated with chemotherapy later, according to a new study in the February 2 issue of the Journal of the National Cancer Institute. (2005-02-01)

Does blue light therapy help acne? Efficacy and evidence is lacking
Conclusions about the effectiveness of blue light therapy for acne are limited. A new systematic review and meta-analysis of 14 randomized controlled trials of blue light therapy for acne shows methodological and reporting limitations -- including small sample sizes, short intervention periods, and variation in reporting quality for acne outcomes. (2019-11-12)

Transgender individuals likely have higher risk for heart disease
Transgender individuals may be at higher risk for heart disease, according to a review article published by Michael S. Irwig, M.D., associate professor of medicine at the George Washington University School of Medicine and Health Sciences, in Reviews in Endocrine and Metabolic Disorders. (2018-08-03)

Time to reassess the value of HRT
It may be time to reassess the value of hormone replacement therapy, following evidence that it reduces the effectiveness of breast screening and causes breast cancer in women over the age of 50, says a leading breast surgeon in this week's BMJ. (2001-12-13)

Annals of Internal Medicine, tip sheet, May 13, 2002
Articles in this addition include 1). New recommendations: doctors should screen all adults for depression, 2). Canadian study finds no gender bias in heart procedures, and 3)Of three treatments, neck pain responds best to manual therapy. (2002-05-20)

The benefits of reperfusion therapy
The wider use of reperfusion therapy in patients with heart attack can save millions of lives in Europe. Effective reperfusion therapy in an AMI patient can cut the individual risk of dying by half. AMI is caused by a sudden blockage of a coronary artery, one of the vessels supplying the heart muscle with oxygen and nutrients. Effective reperfusion therapy provides a timely and sustainable reopening of the blockage. (2009-09-01)

Gut microbiota reveals whether drug therapies work in inflammatory bowel diseases
A study recently completed at the University of Helsinki indicates that the gut microbiota of patients suffering from inflammatory gastrointestinal disorders can be used to predict whether they will benefit from expensive therapies. The study also confirms the key role of therapies that have a beneficial effect on the gut microbiota in inflammatory bowel diseases. (2021-01-26)

New classification better identifies prostate cancer patients to benefit from hormone therapy
A new classification system for evaluating men after radiation treatment for prostate cancer better determines which men may recur and thus may benefit from hormone therapy. Doctors applied the new system to 1,831 previously treated patients. The new classification could alter the course of treatment, which may include hormone therapy sooner and for more men. The study demonstrates a significant improvement in predicting endpoints, including distant metastasis, cause-specific mortality and overall mortality. (2006-11-08)

Study shows combining gene therapy and radiation holds promise
A novel approach that combines gene therapy and radiation therapy for treating prostate cancer has shown promising results for its safety and effectiveness, according to Henry Ford Hospital researchers. The study, published in this month's edition of Cancer Research, shows that patients experienced no significant side effects when treated with gene therapy and radiation therapy. It also showed that the treatment lowered patients' prostate-specific antigen (PSA) and eliminated the cancer in many of them. (2003-11-24)

Palliative care: Music to make patients feel better
Music therapy can enhance terminally ill patients' wellbeing and relaxation. This treatment has been known since the 1970s, but there is little scientific research on the subject. A recent randomized controlled trial by Marco Warth et al. in Deutsches Arzteblatt International (Dtsch Arztebl Int 2015; 112: 788-94) analyzes the effect of music therapy on palliative care patients. (2015-11-30)

Home-based AIDS care program could benefit HIV-infected people in rural Africa
A novel home-based AIDS care programme can achieve good adherence and response to antiretroviral therapy in a rural African setting, according to an Article in this week's issue of the Lancet. (2006-11-01)

LA BioMed 2015 Innovation Showcase
Join us for a full day of networking and learn about the latest developments on the efforts to bring to market technologies developed at LA BioMed. (2015-04-14)

New therapy offers hope to spinal muscular atrophy patients
Children who suffer from the devastating disease spinal muscular atrophy are set to benefit from a new breakthrough in therapy developments by researchers at the University of Sheffield. (2010-06-09)

Task force issues caution on combined hormone therapy
The U.S. Preventive Services Task Force today recommended against the use of combined estrogen and progestin therapy for preventing cardiovascular disease and other chronic conditions in postmenopausal women. The recommendations are posted on the Web sites of Annals of Internal Medicine ((2002-10-15)

Putting genes in a pill
Finding new ways to deliver gene therapy without using viruses as carriers is the aim of research by chemist Michael Nantz at UC Davis. Nantz's lab engineers lipids, oily molecules that can form a protective complex around DNA, to do the same job as a virus. (2003-05-14)

Antihormone therapy linked with higher heart failure risk in prostate cancer patients
Androgen deprivation therapy was associated with a 72 percent higher risk of heart failure in a study of patients with prostate cancer. (2018-11-07)

Prostate cancer survival benefit from combination of androgen suppression and external irradiation
Disease-free survival from advanced prostate cancer could be almost doubled if hormone-suppression therapy is used during and after radiotherapy for a duration of 3 years, suggest authors of an international study in this week's issue of THE LANCET. (2002-07-11)

Occupational therapy improves quality of life for dementia patients and their carers
Occupational therapy can help to improve the ability of people with dementia to perform daily activities and can also reduce the pressure on their caregivers, says a BMJ study published today. (2006-11-16)

Successful implementation of pilot study for HIV antiretroviral therapy in Uganda
Authors of a study in this week's issue of THE LANCET report on the successful implementation of a UNAIDS/Uganda Health Ministry initiative to provide antiretroviral treatment to people with HIV/AIDS in Uganda. (2002-07-04)

MRI and PET/CT can prevent unnecessary treatment of some cervical cancer patients
MRI and PET/CT can help spare patients with clinically operable cervical cancer from unnecessary high-morbidity treatment, however, pretreatment imaging does not lead to increased survival of these patients, a new study shows. (2008-04-11)

Is clot-busting drug safe for kids with strokes?
New research looks at whether clot-busting drugs can safely be given to children who have strokes. The research was released today and will be presented at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012. (2012-02-17)

Risk of gall bladder disease with HRT patches lower than with HRT pills
Use of hormone replacement therapy increases the risk of gallbladder disease but the effects are less with HRT given in skin patches or gels compared with HRT given orally, according to a study published on BMJ.com today. (2008-07-10)

Insulin pumps effective for children with diabetes
Pre-school youngsters with type I diabetes can be treated as successfully with insulin pumps as with daily injections according to Indiana University School of Medicine researchers. (2004-10-18)

Study provides insights on optimal treatment of Paget's disease of bone
In a study of patients with Paget's disease of bone--a common skeletal disorder that can lead to bone deformity, fractures, osteoarthritis, and bone pain -- long-term intensive bisphosphonate therapy conferred no clinical benefit over giving bisphosphonates only when patients felt bone pain. (2017-02-08)

Blood cholesterol levels predict risk of heart disease due to hormone therapy
A new analysis of a subgroup of participants in the Women's Health Initiative hormone therapy clinical trials suggests that healthy, post-menopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy. (2008-05-23)

Gene enhances effects of estrogen on good cholesterol
A genetic variant seems to determine how well women's good cholesterol responds to estrogen therapy. The finding could help doctors identify women most likely to gain a heart benefit from hormone therapy. (2002-03-27)

Katherine High talks gene therapy progress for hemophilia & inherited retinopathies
Gene therapy has shown some of its most promising early results in treating patients with hemophilia and inherited retinal disorders that cause vision loss and blindness, both important research and drug development targets during the career of Katherine High, M.D., President and Chief Scientific Officer of Spark Therapeutics. (2017-01-04)

Hormone therapy may confer more aggressive properties to prostate tumors
Hormone therapy is often given to patients with advanced prostate cancer. While it is true that the treatment prevents growth of the tumor, it also changes its properties. Some of these changes may result in the tumor becoming more aggressive and more liable to form metastases. This is one of the conclusion of a thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden. (2009-06-10)

Can viruses that infect bacteria fight plant disease?
While the medical community has been exploring the use of bacteriophages, a form of virus that can be used to manage bacteria that have become resistant to antibiotics, plant pathologists with the American Phytopathological Society (APS) now say that this same approach may also help fight plant disease. (2003-11-06)

Protective Effect Of Progestin In Hormone Replacement Therapy Appears To Be Dose-Related
To help protect against endometrial cancer, women who take estrogen replacement therapy should also take progestin at least 10 days a month, say researchers at the University of Washington. Progestins are hormones that oppose the effects of estrogen on the endometrial cells that line the uterus. (1997-02-14)

New therapy found to prevent heart failure
A landmark study has successfully demonstrated a 29 percent reduction in heart failure or death in patients with heart disease who received an implanted cardiac resynchronization therapy device with defibrillator (CRT-D) vs. patients who received only an implanted cardiac defibrillator (ICD-only). (2009-06-23)

Fewer wrinkles and firmer skin linked to earlier use of estrogen therapy
Long-term hormone therapy used earlier in menopause is associated with fewer wrinkles and less skin rigidity in postmenopausal women, Yale School of Medicine researchers report in the August issue of Fertility and Sterility. (2005-08-26)

Hormone replacement therapy for postmenopausal women: Does it help or harm your heart?
New evidence published today in the Cochrane Library shows that hormone replacement therapy does not protect post-menopausal women against cardiovascular disease, and may even cause an increased risk of stroke. (2015-03-10)

Britain must embrace psychological therapy for mental health problems
Britain must embrace psychological therapies on a large scale if we are to tackle our mental health problems effectively, argues a leading economist in this week's BMJ. (2006-04-27)

Modern antiplatelet therapy: When is clopidogrel the right choice?
In the current issue of Cardiovascular Innovations and Applications (Volume3, Number 2, 2018, pp. 149-162(14); DOI: 10.15212/CVIA.2017.0049 Punag Divanji and Kendrick Shunk from the University of California San Francisco and The San Francisco Veteran Affairs Hospital, San Francisco, Calif., USA consider when clopidogrel is the right choice in modern antiplatelet therapy. (2018-09-10)

Largest ever study of male breast cancer treatment shows more mastectomy, less radiation than in female disease
University of Colorado Cancer Center researchers used data from 4,276 cases of male breast cancer and 718,587 cases of female breast cancer to show that the disease is treated differently in men than in women. Specifically, male breast cancer is treated with mastectomy more often than female breast cancer, and in cases in which locally advanced female breast cancer is commonly treated with radiation, the treatment is less used in the male disease. (2013-10-31)

Waiting between breast cancer diagnosis and treatment
Daniel Rayson and colleagues suggest their study of the elapsed time from breast cancer detection to first adjuvant therapy in Nova Scotia may point the way toward ways to minimize intervals between steps in breast cancer care. (2004-03-15)

Hormone therapy in early post-menopause has no effect on memory
Hormone therapy taken in the first few years after menopause does not appear to affect a woman's memory, but may lead to increased sexual interest, according to a study published in the Sept. 25, 2007, issue of Neurology, the medical journal of the American Academy of Neurology. (2007-09-24)

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