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Disease Therapy Current Events, Disease Therapy News Articles.
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Kidney disease killer vulnerable to targeted nano therapy
By loading a chelation drug into a nano-sized homing device, researchers at Clemson University have reversed in an animal model the deadliest effects of chronic kidney disease, which kills more people in the United States each year than breast or prostate cancer. (2019-03-04)

New technology for a more efficient treatment of Pompe disease and other metabolic disorders
VIB researchers from UGent and Vrije Universiteit Brussel, together with a team of the firm Oxyrane have developed a new technology that can lead to a more efficient and possibly also cheaper therapy for diseases such as Pompe disease. Oxyrane will now start developing a clinical program for this therapy in Pompe disease. (2012-11-19)

Hepatitis C is not a 'silent disease'
Successful treatment of Hepatitis C patients improves their quality of life and is likely to decrease needs for health care services and increase personal productivity, according to a new study published in the journal Hepatology. (1999-08-11)

No advantage of combination drug therapy for chronic hepatitis B Infection
Results of an international study in this week's issue of The Lancet suggest that pegylated interferon alpha offers the best treatment option for people with chronic hepatitis B infection. (2005-01-06)

Treatment for juvenile offenders shows shows positive results 22 years later
Charles Borduin, a University of Missouri researcher, developed a treatment for juvenile offenders that has become one of the most widely used evidence-based treatments in the world. Now, he has found that the treatment continues to have positive effects on former participants more than 20 years after treatment. (2011-11-17)

Gene Therapy Trial Approved For Rare Anemia
A gene therapy clinical trial for Fanconi anemia, a fatal inherited blood disease, is set to begin at the University of North Carolina at Chapel Hill. (1999-01-22)

Key Peptides Found That Stop -- Even Reverse -- Kidney Disease In Lupus
Northwestern researchers have identified key peptides that halt kidney disease in lupus, an autoimmune disease that attacks the body's own DNA. (1999-05-05)

Antisense Therapy Prevents Burkitt's Lymphoma In Mice
Researchers at Jefferson Medical College have used DNA therapy and the host immune system to stave off the development of cancer in mice. Scientists have used antisense therapy to prevent the development of Burkitt's lymphoma in laboratory mice, showing that this protection is aided by the mouse's own immunity. (1998-08-04)

Urocortin 3 gene therapy increases systolic and diastolic function in heart failure
Mice with heart failure that were treated with AAV8-based gene therapy to deliver the protein urocortin 3 (UCn3) had increased blood levels of UCn3 over a 5-week period and improved heart function. (2018-11-14)

Researchers at UGent and VIB, discovered potential novel treatment against septic shock
Scientists of VIB and UGent, supervised by Peter Vandenabeele, demonstrated in a mouse study that a potential novel treatment for sepsis may consist of the simultaneous neutralization of two harmful cytokines in the blood circulation, namely interleukin-1 and interleukin-18. (2014-02-07)

Study reveals 15-year increase in life expectancy for people with HIV in UK
People with HIV have a 15 years longer life expectancy thanks to improved treatments over the past 13 years, according to a new study published on bmj.com today. (2011-10-11)

Photodynamic therapy used to treat ovarian cancer
Photodynamic therapy (PDT) is one of the most promising methods of treating localized tumors. PDT can be used for treatment in almost all major locations as an independent method or in combination with traditional types of treatment (surgery, radiation, and chemotherapy). (2020-06-08)

Higher risk for heart disease and diabetes associated with androgen deprivation therapy
Men of all ages treated for prostate cancer with androgen deprivation therapy, specifically with gonadotropin-releasing hormone agonists, have an increased risk of diabetes and cardiovascular disease, according to a new study published online Dec. 7 in the Journal of the National Cancer Institute. (2009-12-07)

Effect of hormone therapy on risk of heart disease may vary by age and years since menopause
Secondary analyses of findings from the Women's Health Initiative suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause. Overall, hormone therapy did not reduce the risk of CHD. (2007-04-03)

In treatment of depression, cognitive therapy and medication both effective
Cognitive therapy, when provided by an experienced therapist, may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression, according to an article in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals. (2005-04-04)

Robotic arm could help stroke survivors regain range of motion
A robotic arm that can be worn at home is being developed to help stroke survivors regain the ability to reach and grasp objects and perform basic tasks such as feed themselves. (2005-04-26)

Study: Gene therapy superior to half-matched transplant for 'bubble boy disease'
In new research published online today in Blood, the Journal of the American Society of Hematology reports that children with 'bubble boy disease' who undergo gene therapy have fewer infections and hospitalizations than those receiving stem cells from a partially matched donor. (2015-04-13)

Using math to understand hep. C: Patterns paint picture of who will respond to treatment
New research findings show doctors how to predict whether or not a patient with hepatitis C will respond to traditional therapy. (2008-12-22)

New drug brings unexpected hope in targeting cancer cells
An unexpected finding in preclinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing new therapeutic options for a range of cancers. (2019-02-08)

Breast tenderness in women getting combo hormone therapy associated with increase in breast density
Post-menopausal women who experience new onset breast tenderness after starting combination hormone therapy may have an increased risk of breast cancer compared to women who don't experience breast tenderness, a study by researchers at UCLA's Jonsson Comprehensive Cancer Center has shown. (2011-10-13)

Insulin therapy initially declined and delayed by an average of 2 years
Thirty percent of type 2 diabetic patients don't begin insulin when it's initially recommended, with the average start time being two years later. (2017-09-14)

Androgen deprivation therapy increases risk of heart failure in men with prostate cancer
Men with localized prostate cancer who received androgen deprivation therapy, a hormone treatment, were at significantly higher risk of heart failure than men who did not receive this therapy, according to a Kaiser Permanente study published today in the British Journal of Cancer. (2017-08-24)

Study compares treatments for chronic plaque psoriasis
UV-A therapy was found to be more effective than narrowband UV-B therapy in treating patients with chronic plaque psoriasis, according to an article in the July issue of Archives of Dermatology. (2006-07-17)

Helping an oral diabetes drug go the extra mile
Stephen Buckley and colleagues have reformulated a prospective therapy for type 2 diabetes (T2D) now under clinical investigation as an oral treatment. (2018-11-14)

New treatment model for HIV
In this study, clinical responses to antiretroviral drug therapy are simulated for the first time, and the model is then applied to IM therapy. (2007-07-12)

Rheumatoid arthritis meets precision medicine
Scientists are bringing precision medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new multi-site study. In the near future, patients won't have to waste time and be disappointed with months of ineffective therapy, scientists said. Currently $2.5 billion a year is wasted on therapy that doesn't work. (2018-03-19)

Postmenopausal hormone therapy offers no protection against heart attacks
Although therapy with hormones was once thought to protect women's hearts after menopause, a UCSF-led study has found that, at least for women with heart disease, estrogen plus progestin therapy does not reduce the risk of heart attack or death. (2002-07-02)

First successful double-blind study of gene therapy for Parkinson's disease
A randomized, double-blind gene therapy trial for Parkinson's disease has shown that injection of the glutamic acid decarboxylase gene directly into the brain is safe and can significantly improve motor function in patients who are not responsive to drug treatment. (2011-03-16)

Springer in book partnership with American Society of Gene & Cell Therapy
Springer has signed a co-development partnership with the American Society of Gene & Cell Therapy for the publication of books to be included in the Springer series Advances in Experimental Medicine and Biology. The agreement is to publish four edited volumes per year in the field of gene and cell therapy. (2012-01-16)

August news briefs
Daily alcohol consumption by women whose mothers, sisters or daughters have breast cancer further increases their risk for getting the cancer, according to a Mayo Clinic study in the current issue of the journal, Cancer. A Mayo Clinic study on the use of corticosteroids to treat ulcerative colitis and Crohn's disease shows most patients don't require steroid therapy and that those who do have a poor prognosis. (2001-08-10)

Immune therapy 'untangles' Alzheimer's disease
An immune-based therapy against Alzheimer's disease (AD) not only removes the protein that causes the brain-clogging plaques in the disease, researchers have found. They have discovered that the treatment also unleashes the cell's protein garbage disposal system to rid brain cells of the protein tangles that are the other hallmark of the disease. Thus, said researchers led by Frank LaFerla, immune therapy against AD offers the promise of a broad assault on the disease. (2004-08-04)

Hormone therapy boosts sexual interest but not memory, study finds
Hormone therapy in early post-menopause increases sexual interest, but does not improve memory, according to a study in the Sept. 25 issue of the journal Neurology. (2007-09-24)

Therapists phone it in and keep more patients
New research shows patients who had telephone therapy were more likely to complete treatment than those who had face-to-face sessions. Both were equally effective in reducing depression during treatment. The JAMA-published study is the first large trial to compare the benefits of these two therapies. Phone therapy is a rapidly growing trend among therapists because patients have difficulty getting to therapists' offices. (2012-06-05)

Pioneer Award recipients Robin Ali, Ph.D., Jean Bennett, M.D., Ph.D., and William Hauswirth, Ph.D.
Robin Ali, Ph.D., University College London, Jean Bennett, M.D., Ph.D., Perelman School of Medicine, University of Pennsylvania, and William Hauswirth, Ph.D., University of Florida College of Medicine, are co-recipients of the Pioneer Award, recognized for their leadership and contributions to the field of gene therapy to treat retinal degeneration leading to blindness. (2014-09-03)

Brivaracetam in epilepsy: Added benefit not proven
The indirect comparisons conducted by the drug manufacturer between the new drug and two of ten specified comparator agents were unsuitable for the derivation of an added benefit. (2016-05-27)

UNC scientists author editorial on international trials for vasculitis
Two UNC School of Medicine faculty authored an editorial in the July 15, 2010, New England Journal of Medicine commenting on results from two clinical trials using the drug Rituximab to treat small-vessel vasculitis, a rare autoimmune disease. (2010-07-14)

Radiation plus hormone therapy prolongs survival for older men with prostate cancer
Adding radiation treatment to hormone therapy saves more lives among older men with locally advanced prostate therapy than hormone therapy alone, according to a new study in the Journal of Clinical Oncology this week from Penn Medicine researchers. (2015-01-05)

Although controversial, stem cell therapies exhibit potential in biotechnology markets
Stem cells have enormous potential for repairing damage to the body caused by disease, injury, or aging. When introduced into an injured area of a patient, a stem cell could survive and repopulate the region with different types of cells, forming normal tissue. (2002-06-12)

Gene therapy holds promise for treating inherited Lou Gehrig's Disease
Gene therapy with the glial cell line-derived neurotrophic factor gene halts motor neuron destruction and slows progression of familial amyotrophic lateral sclerosis in laboratory mice, Northwestern University Medical School researchers report. (1999-07-19)

Prognostic markers for prostate cancer patients who receive radiation after surgery
Removal of the prostate gland often eradicates early-stage cancer. But patients whose cancer has spread may need to follow up with what is known as salvage radiation therapy. Researchers at Fox Chase have now determined a better way to monitor outcomes after this procedure. (2010-11-02)

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