Disease Therapy Current Events | Page 25

Disease Therapy Current Events, Disease Therapy News Articles.
Sort By: Most Viewed | Most Recent
Page 25 of 25 | 1000 Results
How immune response differs for natural AAV infection compared to AAV vector for gene transfer?
A new, long-term study examined the antibody response to natural infection with adeno-associated virus in chimpanzees for the purpose of characterizing the broad-based immune responses that could reduce the effectiveness of AAV vector-based gene delivery strategies. The study, which demonstrated the production of antibodies able to cross-neutralize multiple AAV serotypes, is published in Human Gene Therapy Clinical Development. (2016-08-10)

Certain breast cancers have a trait that could be attacked by new therapies
The odds of developing breast cancer increase for women taking hormone replacement therapy to avoid the effects of menopause. New research by University of Missouri scientist Salman Hyder may lead to treatments for breast cancers associated with taking these synthetic hormones. Hyder found that hormone-therapy-related breast cancer cells have a physical feature that could be attacked by therapies. (2013-03-27)

New anti-tumor cell therapy strategies are more effective
Targeted T-cells can seek out and destroy tumor cells that carry specific antigen markers. Two novel anti-tumor therapies that take advantage of this T-cell response are described in articles published in Human Gene Therapy. (2012-10-25)

Study reveals healthy outlook for long-term breast cancer survivors
A new study suggests that disease-free breast cancer survivors maintain an excellent quality of life many years after primary treatment. However, the study also found that the use of adjuvant treatments, such as chemotherapy, tamoxifen, or a combination of both, was associated with a decrease in physical functioning over time. These findings appear in the Jan. 2 issue of the Journal of the National Cancer Institute. (2002-01-01)

Should older men be screened for prostate cancer?
Although guidelines suggest men 75 years or older may not benefit from prostate cancer screening, surveys continue to show high rates of screening in this population. A population-based cohort study published in the May issue of The American Journal of Medicine, researchers followed men 75 to 84 who had been diagnosed with clinically localized prostate cancer. Results reinforce concerns that men 75 years and older may not benefit from prostate cancer screening because of adverse outcomes from aggressive treatment. (2006-05-02)

Statin therapy cost-effective for a wider range of individuals
Statin therapy is cost-effective for a wider range of individuals with vascular disease or diabetes than previously recognised, concludes a study published online today (Thursday May 12, 2005) by THE LANCET. (2005-05-11)

Study identifies women with breast cancer most likely to benefit from aromatase inhibitor
While some breast cancer survivors could benefit from adding aromatase inhibitors to the standard five years of tamoxifen, a new study shows the additional therapy should be weighed carefully for each individual. Tthe study's authors say potential improvement in cancer-free survival beyond five years with the added therapy may be less than two percent for most patients. (2006-10-23)

Study shows dietitians are an effective part of weight loss
A new study in the journal Family Practice indicates that intensive behavioral therapy from dietitians may be a very effective ways for older Americans to lose weight. (2020-02-20)

These molecules could trap viruses inside a cell
Viruses are often used as vehicles for delivery in gene therapy because they're engineered not to damage the cell once they get there, but neglecting to consider how the virus will exit the cell could have consequences. (2019-04-08)

Research uncovers life-saving benefits in the battle against viruses
At-risk patients, such as those with HIV or transplant recipients, could benefit from potentially life-saving study carried out by a University of Surrey led group of international researchers. (2017-04-20)

Triple therapy halves exacerbations in moderate-to-severe COPD
Patients with moderate to severe chronic obstructive pulmonary disease (COPD) can benefit from triple therapy that includes a long-acting beta-agonist, an inhaled corticosteroid and an anti-muscarinic agent, according to researchers in Germany. (2009-10-08)

Lung cancer survival improved by maintenance therapy with pemetrexed
Giving pemetrexed maintenance therapy to patients with non-small-cell lung cancer who have not had disease progression after initial platinum-based chemotherapy improves both overall and progression-free survival. The findings are discussed in an article published online first and in an upcoming edition of the Lancet, written by Dr. Chandra Belani, Penn State Hershey Cancer Institute, Hershey, Pa., and colleagues. (2009-09-19)

Combination therapy could provide new treatment option for ovarian cancer
UCLA study identifies a potential test that may help select patients for whom combination therapy could be most effective. (2017-05-01)

Survival differences seen for advanced-stage laryngeal cancer
The five-year survival rate for advanced-stage laryngeal cancer was higher than national levels in a small study at a single academic center performing a high rate of surgical therapy, including a total laryngectomy, or removal of the voice box, to treat the disease, despite a national trend toward organ preservation, according to a report published online by JAMA Otolaryngology-Head & Neck Surgery. (2014-11-27)

Molecular tumor board helps in advanced cancer cases
With accelerating development of personalized cancer treatments matched to a patient's DNA sequencing, proponents say front-line physicians increasingly need help to maneuver through the complex genomic landscape to find the most effective, individualized therapy. (2014-05-05)

Hypnotherapy helps relieve chest pain
Hypnotherapy seems to relieve severe chest pain that is not caused by a heart condition, known as non-cardiac chest pain, suggests a small study published ahead of print in Gut. (2006-04-19)

Massage therapy shown to improve stress response in preterm infants
A study published recently in Early Human Development, conducted by University of Louisville School of Nursing researcher Sandra Smith, Ph.D., and her team at the University of Utah, found massage therapy that involved moderate pressure and stroking of the soft tissues followed by flexing and extending the joints of the arms and legs increased heart rate variability in male, but not in female preterm infants. (2013-05-14)

Parkinson's disease among patients with inflammatory bowel disease
Patients with inflammatory bowel disease appeared more likely than patients without the disorder to develop Parkinson's disease, while anti-tumor necrosis factor therapy for inflammatory bowel disease was associated with reduced incidence of Parkinson's in a new study that analyzed administrative claims data for more than 170 million patients. (2018-04-23)

Clinical Advances towards the simplification if HIV therapy: First once-daily dosing results for the HIV protease inhibitor, Agenerase ™
Embargoed information for the 8th Annual Conference on Retroviruses and Opportunistic Infections:First once-daily dosing results for the HIV protease inhibitor Agenerase™ and phase II clinical results for its pro-drug, VX-175. (2001-02-06)

Gene delivery of drugs directly into arthritic joints is making the leap to patients
Localized gene delivery to diseased joints to achieve sustained drug production at the site of osteoarthritis or rheumatoid arthritis is gaining momentum, with clinical trials underway in the US and the first arthritis gene therapy recently approved in Korea. (2018-01-22)

Off-the-shelf tool for making mouse models of COVID-19
Researchers at the University of Iowa and Medical University, Guangzhou, in China, have created a gene therapy vector that is essentially an off-the-shelf tool that allows labs to create their own COVID-19 mouse model within a matter of days. This simple tool could help overcome a major research hurdle -- the lack of good, widely available animal models for developing and testing new anti-viral therapies and vaccines for COVID-19. (2020-06-16)

Combination hormone therapy raises women's stroke risk
Combined hormone replacement therapy (HRT) increased the risk of stroke for postmenopausal women of all ages, whether or not they had hypertension. (2003-02-14)

Chronic pain remains the same or gets better after stopping opioid treatment
Stopping long-term opioid treatment does not make chronic, non-cancer-related pain worse and, in some cases, makes it better, Washington State University researchers have found. (2018-07-02)

ASTRO president speaks on prostate cancer at MEDCAC meeting
ASTRO President Anthony Zietman, M.D., spoke before the Medicare Evidence Development and Coverage Advisory Committee meeting today on radiation therapy for treatment of localized prostate cancer. MEDCAC provides advice and recommendations to the Centers for Medicare and Medicaid Services for what is covered by Medicare and Medicaid, based on scientific evidence. Today's meeting focused on the risks, benefits and outcomes of radiation therapy treatments for localized prostate cancer as compared with watchful waiting. (2010-04-21)

Mesenchymal stem cells offer novel treatment approach for Crohn's disease fistula
A growing body of clinical evidence shows that transplantation of a patient's own mesenchymal stem cells (MSCs) to achieve a cure and prevent recurrent of Crohn's disease-related fistula can be a safe and effective addition to surgery. (2017-09-14)

What is the role of focal therapy in low-risk prostate cancer?
In the July issue of European Urology, the scientific journal of the European Association of Urology, S. Eggener et al. discussed in a recent study the significance and impact of focal therapy for low-risk cancer patients. (2010-05-18)

Getting SAD is more than having the blues
While many people believe that Seasonal Affective Disorder (SAD) amounts to feeling gloomy in the winter, a University of Rochester research review emphasizes that SAD is actually a subtype of major depression and should be treated as such. (2007-01-24)

OHSU researchers uncover cause, possible treatment for abdominal fat in postmenopausal women
Oregon Health & Science University researchers have unveilled research results that help explain why middle-aged women develop central body fat. The announcement took place during the 2005 Society for Endocrinology annual meeting today in San Diego. The OHSU research team has also conducted initial testing of estrogen replacement therapy as a possible method for counteracting the problem. (2005-06-06)

Use of estrogen plus progestin associated with increased risk for certain type of blood clot
Women who take the hormone therapy estrogen plus progestin have double the risk for venous thrombosis, a type of blood clot, according to an article in the October 6 issue of JAMA. (2004-10-05)

Disease-free, overall survival inferior for black women with HR-positive breast cancer
Results are not explained by lack of access to care or more advanced stage. Chemotherapy, hormonal therapy adherence was similar among groups. (2009-12-11)

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk
Can estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estrogen via a skin patch had reduced beta-amyloid deposits, the sticky plaques found in the brains of people with Alzheimer's disease, a Mayo Clinic study published this month in the Journal of Alzheimer's Disease found. Ultimately, these deposits harm neurons, leading to cognitive problems. (2016-07-12)

Mayo Clinic collaborates to advance Crohn's treatment
A study led by Mayo Clinic has found that infliximab (Remicade) administered alone (monotherapy) or in combination with azathioprine is a more effective treatment for patients with moderate to severe Crohn's disease than azathioprine alone. (2008-10-06)

Advanced prostate cancer has an unexpected weakness that can be targeted by drugs
Kanazawa University researchers reported that the SUCLA2 gene is frequently involved in the deletion of the tumor suppressor gene RB1 in advanced prostate cancer. RB1 deletion makes cells resistant to hormone therapy but SUCLA2 deletion induces a metabolic weakness. The study showed that thymoquinone selectively killed SUCLA2-deficient prostate cancer cells in vitro and in vivo. The findings highlight a vulnerability of advanced prostate cancer cells that can be targeted by drugs. (2020-10-07)

Gene therapy may be effective in treating PAH
Gene therapy has been shown to have positive effects in rat models of pulmonary arterial hypertension (PAH), according to researchers at the University of Adelaide in Australia. (2010-05-19)

New research from Lawson uncovers important molecule in ovarian cancer
Scientists at Lawson Health Research Institute have uncovered an important new target for ovarian cancer therapy. Contrary to current research this new study found that LKB1 is an important molecule in the cancer's promotion and survival. Their research definitively shows that ovarian cancer cells still have LKB1 and that this molecule allows ovarian cancer spheroids to change their metabolism, promote tumor cell survival and make them more resistant to chemotherapy. (2015-07-22)

2-week course of sleep aid increases CPAP adherence in OSA patients at 6 months
New research suggests that patients newly diagnosed with obstructive sleep apnea who use a short-course of the sleep aid, eszopiclone, when beginning continuous positive airway pressure therapy, are more adherent with therapy in six months. (2009-05-17)

Radiation after surgery keeps high-risk prostate cancer at bay
An analysis of data involving more than 2,000 patients from 17 US institutions demonstrates that men with high-risk prostate cancer who receive radiation therapy after a prostatectomy were less likely to have a recurrence of disease. What's more, men whose cancer persists after surgery were less likely to see the cancer spread if they receive radiation. (2007-10-30)

Evidence supports blocking immune response to enhance viral therapy against solid tumors
Following several years of study, investigators have found more evidence that viral therapy to treat solid tumors can be enhanced by blocking the body's natural immune response. (2013-03-13)

Ribociclib plus hormone therapy extends survival for patients with premenopausal advanced hormone receptor-positive breast cancer
Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center. (2019-06-01)

Study supports triple combination therapy for HIV
New evidence in this week's BMJ supports the use of up to three antiviral drugs (triple therapy) to treat people with HIV. (2002-03-28)

Page 25 of 25 | 1000 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.