Drosophila Current Events

Drosophila Current Events, Drosophila News Articles.
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Completion of the Drosophila genome sequence
The DNA sequence of the Drosophila genome will be released and published today. This exciting achievement marks the culmination of a century of rewarding fruit fly research into basic biological mechanisms, and demonstrates the importance of this simple organism to understanding human biology and disease. (2000-03-22)

48th annual Drosophila Research Conference, Philadelphia Marriott, March 7-11, 2007
Members of the press are invited to attend the 48th annual Drosophila Research Converence to be held at the Philadelphia Marriott Hotel from March 7-11, 2007. There will be over 1,300 attendees at the meeting with 1,000 platform and poster presentations. (2007-01-11)

Identifying Piwi's partners
Reported in the August 15th issue of G&D, Dr. Mikiko Siomi and colleagues from the Institute for Genome Rsesearch in Japan have identified the elusive small RNA partners of Piwi proteins -- lending new insight into the gene silencing pathways mediated by small RNAs in Drosophila. (2006-07-31)

microRNA function in neurogenesis
In the October 15 issue of G&D, Dr. Fen-Biao Gao and colleagues at UCSF report that microRNA-9a (mir-9a) regulates neural development in the fruit fly, Drosophila. (2006-10-05)

A fly (genome) like any other fly
Biologists may well know more about the fruit fly Drosophila melanogaster, including its entire genome sequence, than about anything else with legs. Now a new effort will re-sequence the DNA of 50 different strains of Drosophila, addressing questions and developing tools that could eventually be used to look at the genetic differences between individual humans. (2004-04-20)

Can an old gene learn new tricks?
The morphological complexity of mammals, as compared to invertebrates, is thought to have arisen through advantageous genetic changes that occurred during the course of evolution. A new research study suggests that the evolution of higher-order vertebrate organ systems can result from primitive developmental genetic programs that are, in a sense, recycled for entirely new structures. (2004-09-13)

Insects share the same signaling pathway to form their 3-dimensional body
Zoologist shows that beetles, bugs and crickets control their body shape through Fog signalling / publication in 'eLife'. (2019-10-21)

RNAi and telomere length
A team of Russian scientists, led by Dr. Vladimir Gvozdev (Russian Academy of Sciences) reports on a novel link between RNAi and telomere maintenance in the Drosophila germline. (2006-01-31)

Algorithms to locate centrioles in the cell
Investigators from the UEx have developed a methodology with new algorithms to analyse the location of the centriole in a model cell. Thanks to this technology, they have been able to discover how the actin cytoskeleton, is involved in the polarised placement of centrioles in Drosophila, just as happens in vertebrates. However, the planar cell polarity-dependent factors which affect the location of the centriole in humans and in vertebrates are not found in Drosophila (2018-12-11)

Epigenetic regulation by the MMB/dREAM complex
In the March 1 issue of G&D, Dr. Joseph Lipsick and colleagues demonstrate that proteins encoded by the Myb oncogene and the RB tumor suppressor gene function together in the Drosophila MMB/dREAM complex to epigenetically regulate mitotic cell cycle progression. (2008-03-05)

A study on cell migration provides insights into the movement of cancer cells
The migration of groups of cells in order to form tissues is common during the development of an organism. Discovering how these multiple movements are achieved is not only crucial to understand the basic principles of development but provides new information and insights for further research into processes associated with the spread of cancer. (2013-11-21)

Conserved role for Ovo protein in reproductive cell development in mice and fruit flies
University of Tsukuba-led research identified a role for the Ovo protein in the development of both mouse and Drosophila germ cells. Drosophila Ovo was found to activate genes for egg and sperm production, while suppressing expression of genes for development of somatic tissues of the body. The mouse Ovo was also shown to play an important role in germ cell development, revealing a mechanism conserved throughout evolution. (2017-01-23)

Nitric oxide is essential for animal development
By employing the efficiency of Drosophila genetics, researchers have discovered that nitric oxide (NO), a versatile signalling molecule involved in a diversity of clinically important cellular functions, is essential for an organism's development. (2004-10-25)

IU fruit fly scientists capture $20 million grant
Researchers at Indiana University Bloomington, Harvard University, Cambridge University (U.K.) and the University of California at Berkeley have been told by the National Institutes of Health that their request for approximately $20 million in continued funding for FlyBase has been approved. Some $3 million of that money will come directly to IUB, which houses FlyBase, the most comprehensive database of Drosophila (fruit fly) information available to scientists. (2003-11-10)

'Fly' meeting to spotlight research advances in genetics
Genetics Society of America's Drosophila Research Conference, March 26-30, 2014, in San Diego will feature latest research on such topics as cell biology and the cytoskeleton, RNA biology, screening of experimental therapeutics in fly models as well as fly models of such human diseases as cancer, epilepsy, heart disease and diabetes. Meeting also will include an invited keynote presentation by Bruce Alberts, Ph.D., and a preview of the new feature film, 'The Fly Room.' (2014-03-11)

'Breaking bad': Insect pests in the making
Of thousands of known species of Drosophila fruit flies, just one is a known crop pest, depositing eggs inside ripening fruit so its maggots can feed and grow. New research from UC Davis shows the similarities and crucial differences between this pest and its close relatives -- and that one related fly has potential to also become a pest. (2014-03-17)

Driving diversification
In the upcoming issue of G&D, Dr. Yuh-Nung Jan and colleagues at UCSF lend surprising new insight into the regulation of dendrite morphology in the fruit fly, Drosophila. (2006-10-05)

Why all-nighters don't work: How sleep and memory go hand-in-hand
Scientists have long known that sleep, memory and learning are deeply connected but how has remained a mystery. The question is, does the mechanism that promotes sleep also consolidate memory, or do two distinct processes work together? In other words, is memory consolidated during sleep because the brain is quiet or are memory neurons actually putting us to sleep? In a recent paper in the journal eLife, Brandeis researchers make a case for the latter. (2015-01-23)

Opening the O-box
Dr. Maki Asano and colleagues have discovered a novel protein motif that regulates Drosophila cell cycle progression by targeting the origin recognition complex (ORC1) for degradation by the ubiquitin ligase, APC. The ORC destruction box, or the (2005-09-29)

The clustering of Hox genes is not necessary for their proper function
A research group led by Professor Alfredo Ruiz, of the Universitat Autònoma de Barcelona, has found that the Hox gene complex has been rearranged differently in several Drosophila species. The function of Hox genes seems to be conserved despite the rearrangements. Thus Hox gene clustering in the Drosophila genome seems to be the result of evolutionary history more than that of functional necessity. The research will appear in this week's issue of Genome Research. (2005-05-02)

Drosophilists fly into D.C. for 51st Annual Drosophila Research Conference
More than 1,600 genetics researchers who use Drosophila melanogaster (the fruit fly) as the workhorse to study basic aspects of biology ranging from memory to cancer, will be gathering in Washington, D.C., for the 51st Annual Drosophila Research Conference, sponsored by the Genetics Society of America, and beginning this evening at the Marriott Wardman Park. Scientists will present their research at plenary, platform, and poster sessions during this four-day meeting. (2010-04-07)

Using fruit flies to identify new treatment for a colorectal cancer patient
Erdem Bangi and colleagues demonstrate a new approach to developing personalized therapy for a patient with treatment-resistant colorectal cancer: using a fruit fly genetically modified with a patient's own cancer mutations to test candidate treatments. (2019-05-22)

Making sense of antisense microRNAs
Three independent papers in the Jan. 1 issue of G&D report on the discovery of a bidirectionally transcribed microRNA (miRNA) locus in Drosophila. (2007-12-31)

Genital shape key to male flies' sexual success
Having genitals of a certain shape and size gives male flies a major reproductive advantage, new research shows. (2021-01-15)

New way to conquer disease-causing nematodes in flies has implications for human diseases
A Science article published on July 9, 2010, describes the discovery of an alternative form of evolution that helps Drosophila flies conquer nematodes that sterilize them. Nematodes are among the most abundant, diverse and destructive parasites of plants and animals. (2010-07-08)

New lab manual for studying the biology of the nervous system in Drosophila is released
A newly released book, (2010-05-20)

A new system for collaboration in cell communication
Investigators from the Institute of Research in Biomedicine have identified a new signalling mechanism among cells in the fruit fly, Drosophila melanogaster. The researchers found that two independent groups of cells generate the same signal by different pathways and that these cells subsequently act together to send the signal to the target cell. In this manner, the receptor cell receives the signal from two distinct sources. (2007-06-26)

Drosophila innate immunity: Another piece to the puzzle
EPFL scientists have discovered a new receptor in the fruit fly immune system that detects bacterial infections. The finding opens up clues for our own immune responses. (2016-11-15)

Genes activated in metastasis also drive the first stages of tumour growth
Researchers headed by Jordi Casanova at the Institute for Research in Biomedicine (IRB Barcelona) now demonstrate that genes activated during metastasis are also able to initiate primary tumour development, and they explain the molecular mechanism involved. Made using the fly model Drosophila melanogaster, this finding has been published in PloS Genetics this week. (2018-02-20)

Known tumour suppressor gene found essential for development, regeneration&stress-response
- Experiments carried out in the Drosophila fly have led to the identification of the headcase (hdc) gene as pivotal for adult progenitor cells, allowing them to undergo metamorphosis and give rise to adult tissue structures. - The study by IRB Barcelona's Development and Morphogenesis in Drosophila lab has been published in PLOS Genetics. (2021-02-09)

Female fly genomes also populated with de novo genes derived from ancestral sequences
A presentation at Genetics Society of America's Drosophila Research Conference builds the case that de novo genes derived from ancestral non-coding DNA can spread through a species. (2014-03-26)

A balancing act in Parkinson's disease: Phosphorylation of alpha-synuclein
Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease. Previous studies have indicated that phosphorylation of alpha-synuclein at amino acid 129 is a key event in alpha-synuclein-mediated nerve cell toxicity. However, Mel Feany and colleagues, at Brigham and Women's Hospital, Boston, have now identified a counterbalancing role in nerve cell protection for phosphorylation of alpha-synuclein amino acid 125. (2009-10-12)

Picky-eater flies losing smell genes
The specialist fruit fly Drosophila sechellia is losing genes for smell and taste receptors 10 times faster than its generalist relative Drosophila simulans. The findings could help researchers understand how some insect pests adapt to feeding on a particular plant. (2007-04-02)

Flies may reveal evolutionary step to live birth
A species of fruit fly from the Seychelles Islands often lays larvae instead of eggs, UC San Diego biologists have discovered. Clues to how animals switch from laying eggs to live birth may be found in the well-studied species' ecology and genes. (2008-11-24)

Scientists construct a physical map of the Drosophila buzzatii genome
An international team of researchers led by the Universitat Autònoma de Barcelona Professor Alfredo Ruiz, has launched in this month's issue of the journal Genome Research the first detailed physical map of the Drosophila buzzatii chromosomes. This fly species is used worldwide as a model for studies in evolutionary genetics. (2005-06-29)

An invasive Asian fly is taking over European fruit
Coming from the Asian continent, Drosophila suzukii has only been in Spain for a short time. Far away from slipping through into the Iberian Peninsula, it accelerated towards the north of Europe where it has already crossed the Alps. Amongst its preferred target are cherries and red fruits but any type of fruit is suitable for it to lay its eggs. This insect is posing a threat to the fruit of more and more European countries. (2012-03-16)

Study reveals key role of mRNA's 'fifth nucleotide' in determining sex in fruit flies
A team of scientists led by the University of Birmingham has shown how a common mRNA modification, N6-methyladenosine (m6A), regulates gene expression to determine the sex of fruit flies. (2016-11-30)

NYU scientists set stage for understanding how color vision is processed
New York University biologists have mapped the medulla circuitry in fruit flies, setting the stage for subsequent research on how color vision is processed. The work, which appeared in the journal Current Biology, will allow future scholarship to explore how color vision is processed in the optic lobe of the fruit fly Drosophila, providing a paradigm for more complex systems in vertebrates. (2008-03-25)

X chromosome dosage compensation proven in germ cells
X chromosome dosage compensation does occur in germ cells. A study published today in the open access journal Journal of Biology reveals that expression of the genes on the X chromosome is doubled in Drosophila germ cells to compensate for the missing second X chromosome. (2006-02-15)

Dual role of fruit fly protein in connecting chromosome copies
Research at Nagoya University has identified a double function for the Drosophila Dmt protein in both establishing and maintaining cohesion whereby identical chromatids pair during DNA replication. Dmt localizes to regions of tightly packed chromatin through interactions with other proteins to launch cohesion, and protects cohesion at other cell cycle timepoints by binding different proteins. Equivalent processes in vertebrates involve actions of two distinct proteins, suggesting that Dmt represents an intermediate stage of protein evolution. (2017-06-01)

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