Drug Delivery Current Events

Drug Delivery Current Events, Drug Delivery News Articles.
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Advances in nanoparticles as anticancer drug delivery vector: Need of this century
This review article provides a summary of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. (2020-06-04)

Patent Received On Drug Delivery System
Researchers have received a patent for a new drug delivery system that could remove some side effects of chemotherapy. The system, which is being studied in animals, incorporates drugs such as chemotherapy into macrophage cells. The cells are localized in certain parts of the body and return to their original location when given intravenously. (1999-01-06)

A summary of electrospun nanofibers as drug delivery system
Recently, electrospun polymeric nanofibers have proven to be an interesting strategy for drug delivery systems application.This review presents an overview of the reported drugs loaded into polymeric nanofibers, to be used as drug delivery systems. (2018-12-14)

Ethosomes as vesicles for effective transdermal delivery: From bench to clinical implementation
Ethosomes are ethanolic nanovesicles that possess abundant amount of ethanol in its core which provides fluidity to the lipid bilayers and thus by this effect, improves the delivery of molecules into the deep skin layers. These vesicles are capable of enclosing both hydrophilic and lipophilic drugs. (2016-10-07)

Four new us patents granted to Acrux for transdermal drug delivery
Acrux Limited (ASX: ACR), the Australian pharmaceutical company that specialises in products delivering therapeutic drugs through the skin, today announced that it has been granted four more US patents relating to its transdermal drug delivery technology. (2005-09-26)

A new direction in ophthalmic development: Nanoparticle drug delivery systems
Most ophthalmic diseases are usually treated with topically administered drug formulations (e.g. eye drops). Their main disadvantage is the short time of contact with the eye, which leads to a low degree of absorption of the active substance (less than 5 percent of the drug administered). This requires frequent instillation, which usually leads to a high systemic exposure. (2017-01-02)

OptiNose presents data on highly effective migraine treatment
OptiNose AS will present new Phase II data at the American Headache Society meeting in Boston on June 28. The Phase II clinical trial studied the safety and efficacy of sumatriptan, a migraine drug, when delivered to the nose by the OptiNose powder delivery device. The OptiNose and sumatriptan combination produced efficacy results comparable to previously published results on sumatriptan injections, the fastest (and also most painful) migraine treatment currently available. (2008-06-28)

Drug-loaded nanocarriers in tumor targeted drug delivery
Nanoparticulate delivery systems in cancer therapies provide better penetration of therapeutic and diagnostic substances with the cancerous tissue in comparison to conventional cancer therapies. (2016-03-07)

Flexible drug delivery microdevice to advance precision medicine
A KAIST research team has developed a flexible drug delivery device with controlled release for personalized medicine, blazing the path toward theragnosis. They fabricated a device on a rigid substrate and transferred a 50 μm-thick active drug delivery layer to the flexible substrate via inorganic laser lift off. The fabricated device shows mechanical flexibility while maintaining the capability of precise administration of exact dosages at desired times. (2018-08-12)

Partnership to develop subretinal drug delivery technology
Preceyes B.V. and Nightstar have entered into a collaboration for the development of a high-precision drug delivery technology in the eye. Nightstar will use the Preceyes robotic device to further refine the delivery of gene therapy to the subretinal space for a range of inherited retinal diseases. In the course of the collaboration, Nightstar will purchase the PRECEYES Surgical System for use in human gene therapy trials. (2016-02-29)

Women feel unprepared for operative deliveries
Antenatal classes do not adequately prepare women for operative deliveries (caesarean sections, use of ventouse or forceps), according to study in this week's BMJ. (2003-11-13)

UK Faculty Members Find Way To Speed Response Of Viagra
Two University of Kentucky College of Pharmacy faculty members have developed a nasal drug delivery system for Viagra causing the drug to work almost immediately after dosing, which could prevent overdosing. (1999-01-06)

High-precision robotic system from Eindhoven targets ocular surgery
Preceyes' high-precision robotic system targets ocular surgery, with vitreoretinal surgical procedures as the initial target market. The technology promises to improve the delivery of existing ocular surgery as well as enables the development of new treatments such as high-precision drug delivery, assisting eye surgeons in performing the most demanding surgical tasks. Preceyes, a spin-off of Eindhoven University of Technology, has now entered into collaborations with NightstaRx (Nightstar) and the University of Oxford. (2016-02-29)

Ingestible injections made possible by a tortoise-inspired drug delivery device
A new ingestible device, inspired by the self-orienting shape of the leopard tortoise's shell, may soon be used to administer drugs by injecting them through the stomach wall. (2019-02-07)

Optimized inhaler mouthpiece design allows for more effective drug delivery
Redesign of mouthpieces for aerosol inhaler devices allows for drugs to be more effectively delivered to the lungs and may allow for a new class of aerosol administered medications. (2009-10-21)

Stealth particles to target tumors
Stealth nano particles may some day target tumor cells and deliver medication to specific body locations, according to Penn State chemical engineers. (2005-08-31)

WSU researchers develop natural protein cage for improved cancer drug delivery
Washington State University researchers have developed a unique, tiny protein cage to deliver nasty chemotherapy chemicals directly to cancer cells. Direct delivery could improve treatment and lessen what can be horrendous side effects from toxic drugs. (2015-10-26)

Colonic navigation
Nanoparticles could help smuggle drugs into the gut, according to a study published this month in the International Journal of Nanotechnology. (2010-11-04)

Do cesarean delivery's effects on birth hormones impact a newborn's neurodevelopment?
Cesarean section delivery and vaginal delivery lead to different hormonal exposures that may affect a newborn's development, according to an article published in the Journal of Neuroendocrinology. (2020-11-04)

Novel thermal ablation system for transdermal drug delivery
The size of protein-based drug molecules prevents their absorption into the body when taken orally making injection (intramuscularly, subcutaneously, intravenously, etc.) the only effective delivery method. Research into transdermal drug delivery systems to make taking these drugs easier and cheaper has lead Japanese researchers to develop a new transdermal thermal abrasion system. It uses near-infrared light to irradiate gold nanorods in a gel skin patch to increase skin permeability for improved drug delivery. (2017-07-26)

News tips from the Journal of Neuroscience
The current issues contains articles on (2004-07-15)

Novel anti-cancer nanomedicine for efficient chemotherapy
Researchers have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for efficient cancer chemotherapy. (2019-09-17)

Get a load of ZIF! Better delivery of cancer immunotherapy
An antibody loaded onto a porous metal organic framework is released by the acidic environment that surrounds tumors, avoiding the adverse effects of administering the antibody alone. (2021-02-11)

$1.7 million for Rutgers anti-HIV drug research
Rutgers has just received new funds to support the pursuit of new ways to combat the virus. Patrick J. Sinko, Parke-Davis Professor of Pharmaceutics and Drug Delivery has received an NIH MERIT award for more than $1.7 million to support up to 10 years of Sinko's research into nanotechnology-based, targeted drug delivery for the treatment of the HIV infection. (2006-06-06)

Heat-controlled drug implants offer hope for future
Scientists test insulin release from thermally-triggered microgel films. (2004-09-13)

Fluorescent probes offer fuller view of drug delivery in cells
Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside living cells. (2019-11-01)

Proof of sandwiched graphene-membrane superstructure opens up a membrane-specific drug delivery mode
Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Tsinghua University (THU) proved a sandwiched superstructure for graphene oxide (GO) that transport inside cell membranes for the first time. (2019-06-07)

UCSB scientists discover potential drug delivery system
Scientists at UC Santa Barbara have discovered a potential new drug delivery system. The finding is a biological mechanism for delivery of nanoparticles into tissue. The results are published in this week's Proceedings of the National Academy of Sciences. (2009-08-24)

Tiny capsules deliver
A tiny particle syringe composed of polymer layers and nanoparticles may provide drug delivery that targets diseased cells without harming the rest of the body, according to a team of chemical engineers. This delivery system could be robust and flexible enough to deliver a variety of substances. (2009-01-12)

Is caesarean section linked to postnatal depression?
Elective caesarean section does not protect women from postnatal depression, according to a study published on (2005-02-24)

Chemical library aids in developing drug system for nerve damage
Shelly Sakiyama-Elbert, Ph.D., an assistant professor of biomedical engineering at Washington University in St. Louis, has screened a large number of molecules to find which ones have varying affinity, or attraction, to a sugar that binds nerve repair drugs called heparin, as well as a nerve repair protein called nerve growth factor. She is looking for protein sequences that bind to drugs to help a drug delivery vehicle provide timed release of a drug. (2005-04-12)

Promising use of nanodiamonds in delivering cancer drug to kill cancer stem cells
A study led by the National University of Singapore found that attaching chemotherapy drug Epirubicin to nanodiamonds effectively eliminates chemo-resistant cancer stem cells. (2015-01-25)

Nanotechnology helps track and improve drug action in pancreatic cancer
Scientists from Sydney's Garvan Institute of Medical Research, in collaboration with colleagues from the Beatson Institute for Cancer Research in Glasgow UK, have been able to show ways in which we can markedly improve drug targeting of solid tumors, using tiny 'biosensors' along with new advanced imaging techniques. In real time and in three dimensions, these technologies can show us how cancers spread and how active cancer cells respond to a particular drug. (2013-06-12)

Better chemo drug adsorption onto targeted delivery capsules
One of the challenges in cancer research is improving the delivery of chemo drugs to enhance their efficacy while decreasing the risk of side effects. In a new study published in EPJ E, Scientists from Argentina perform a theoretical prediction of adsorption of a well-known chemo drug onto active carbon with aluminium inclusions, to show its potential as an oral chemotherapy delivery capsule. (2018-09-18)

Global experts discuss new approaches and innovations in ocular drug delivery systems
A special issue 'Ocular Drug Delivery' has just been published in the journal Drug Delivery and Translational Research. It is co-edited by Dr. Ilva Rupenthal from the University of Auckland, New Zealand, and Michael O'Rourke, President of Scotia Vision Consultants. The special issue contains articles by recognized global experts in the field, covering a broad spectrum of drug delivery topics including current challenges faced and establishment of suitable models to drive future technology success. (2016-11-07)

More efficient drug delivery within the brain by utilizing LAT1
According to a new study carried out at the University of Eastern Finland, the distribution of drug molecules within the brain can be improved by utilizing LAT1, which is expressed highly in the brain. (2019-09-24)

New method reveals how well cancer drugs hit their targets
Scientists have developed a method to measure how well cancer drugs reach their targets inside the body. It shows individual cancer cells in a tumor in real time, revealing which cells interact with the drug and which cells the drug fails to reach. The findings could help clinicians decide the best course and delivery of treatment for cancer patients in the future. (2018-07-12)

Springer launches Drug Delivery and Translational Research
Starting in February 2011, Springer will publish a new international, peer-reviewed journal Drug Delivery and Translational Research. Focusing exclusively on translational aspects of drug delivery, the bimonthly journal will provide a unique forum for publication of high-quality research. It is an official journal of the Controlled Release Society. (2010-07-12)

Boston University researchers develop novel drug delivery system
A team of researchers led by Boston University biomedical engineer and chemist Mark Grinstaff has developed a unique material and drug delivery mechanism that could pave the way for implants that release a drug at a designated rate for months. (2012-01-31)

Drug-delivering device streamlines tuberculosis treatment in pigs
Scientists have created a retrievable, wire-like device that safely resides in the stomach and releases large dosages of drugs over several weeks. (2019-03-13)

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