Drug Development Current Events

Drug Development Current Events, Drug Development News Articles.
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Teaching old drugs new tricks in the fight against infectious diseases
A new article looks at how currently available drugs for various conditions might be repurposed alone or in combination with other drugs to treat infectious diseases. (2017-07-07)

Greater efforts are needed to encourage patients to report adverse drug reactions
In a review of published studies addressing patients' perceptions and factors influencing their reporting of adverse drug reactions, most patients were not aware of reporting systems and others were confused about reporting. (2016-11-21)

Study estimates R&D spending on bringing new cancer drug to market
Research and development costs are a common justification for high cancer drug prices and a new study published by JAMA Internal Medicine offers an updated estimate of the spending needed to bring a drug to the US market. (2017-09-11)

New pharmaceutical building block could accelerate drug development
Researchers have developed a family of reagents that can add tight, ring-shaped structures that boost a drug's beneficial properties to a wide variety of drug candidates. (2016-01-14)

Is the drug overdose epidemic unique to the United States?
Is the current American drug overdose epidemic an isolated phenomenon? Have other high-income countries experienced similar increases in drug overdose mortality, or are they likely to going forward? A new study published in Population and Development Review addresses these questions. (2019-02-21)

Environment contributes to drug tolerance
The setting in which drugs are taken can be as big a contributor to developing a tolerance as the drugs themselves. For more than a decade, psychologist Antonio Cepeda-Benito has studied how learning and environment facilitate the development of drug tolerances. (2000-10-10)

A new book considers the interaction between public spaces and drug use
Dr. Stephen Parkin, a Research Fellow in Human and Health Sciences at the University of Huddersfield, has published a book focusing on how public spaces affect more harmful episodes of injecting drug use. (2013-08-02)

MCW Research Foundation licenses invention for stroke treatment
A new drug to prevent brain damage in stroke victims was licensed by the Medical College of Wisconsin Research Foundation to Taisho Pharmaceutical Co., Ltd. The new treatment was co-developed in the laboratories of Richard Roman, Ph.D., and David R Harder, professors of physiology at the Medical College, in cooperation with Taisho scientists. The Research Foundation awarded Taisho exclusive, world-wide rights to further develop and commercialize the drug. (2005-09-23)

First and only therapeutic drug for ALK-positive lung cancer approved
FDA approves the drug crizotinib for use with a subset of lung cancer patients known as ALK-positive -- a (2011-08-31)

Elsevier and Bentham Science agree to a co-distribution alliance
Elsevier and Bentham Science are collaborating to make certain eBooks widely available for the researchers and readers. (2015-12-17)

Why are the best malaria drugs not being used in Africa?
Despite changes in policy in many African countries, most cases of malaria are still treated with old drugs that often fail, say researchers in this week's BMJ. (2005-09-29)

How the brain puts the brakes on the negative impact of cocaine
Research published by Cell Press in the Jan. 12 issue of the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine. The study describes protective delayed mechanism that turns off the genes that support the development of addiction-related behaviors. The findings may lead to a better understanding of vulnerability to addiction and as well as new strategies for treatment. (2012-01-11)

Are women really under-represented in clinical trials?
Several studies have reported a lack of gender diversity in clinical trials, with trials including mostly adult males; however, a recent review of publicly available registration data of clinical trials at the US Food and Drug Administration for the most frequently prescribed drug classes found no evidence of any systemic significant under-representation of women. The findings are published in the British Journal of Clinical Pharmacology. (2018-01-11)

New drug SAK3 may offer hope to Alzheimer's disease patients
A new drug could lead to the development of the first disease-modifying drug to prevent Alzheimer's disease. (2017-01-26)

Initially recommended drug dosages often too high, study finds
More than 20% of the drugs approved in the United States are approved at a dosage level that is later discovered to be too high, resulting in the subsequent lowering of the recommended dosage level, according to research conducted at Georgetown University's Center for Drug Development Science (CDDS). Two papers on this subject have been published in the August issue of the British journal Pharmacoepidemiology and Drug Safety. (2002-08-13)

Advancing Neurodegeneration Drug Discovery and Development
Does having cancer decrease your risk of developing neurodegenerative diseases? Why do many cancer drug targets overlap with targets for neurodegenerative diseases? This meeting will address these questions to help advance therapeutic development. (2015-05-14)

New watchdog for adverse drug events needed
In an editorial in the Nov.13 issue of the Canadian Medical Association Journal, Editor John Hoey speculates on whether the current Canadian system of relying on the conscientious participation of drug companies to issue warnings to physicians about potentially serious adverse events is adequate. (2001-11-12)

New hybrid drug plugs the hole in malaria drug resistance
The World Health Organization recommends treating malaria with artemisinin combination therapy (ACT), consisting of artemisinin and another drug. However, malaria resistance to ACT has already started emerging in Southeast Asia. Scientists at the National University of Singapore have now developed a novel hybrid drug that combines a killing factor with an agent that reverses drug resistance. The hybrid drug is very effective against chloroquine- and artemisinin-resistant malaria, presenting a new avenue for treating resistant malaria. (2016-04-11)

Potential new treatment for cocaine addiction
A team of researchers led by Cardiff University has discovered a promising new drug treatment for cocaine addiction. (2016-08-31)

LSTM to lead EU project to coordinate antimalarial drug research
The European Commission is funding a two year, €500,000 project to co-ordinate European and international research into the development of new drugs to treat malaria. The CRIMALDDI project is being led by the Liverpool School of Tropical Medicine and brings together key players in the antimalarial drug discovery fields including the World Health Organization, the Medicines for Malaria Venture and leading research organizations across Europe. (2009-08-20)

BioAnalytix advances the biologic drug development
Two years ago, Northeastern University's College of Science and the Barnett Institute launched BioAnalytix to help fill a critical gap in the area of biologic drug development and launch. Now the company is working with pharmaceutical companies around the world on later-stage drug development. (2014-06-11)

Georgetown University forum to explore scientific approaches for expediting drug development
This workshop, titled (2002-01-06)

Analysis highlights the importance of pharmacology measures in early clinical trials
A new analysis published in the British Journal of Clinical Pharmacology indicates that 'first-in-man' clinical trial protocols in the Netherlands often lack a consistent consideration of pharmacokinetic and pharmacodynamic aspects in establishing drug doses. (2017-10-04)

National conference focuses on drug abuse and addiction in minority communities
On September 24-26, the National Institute on Drug Abuse (NIDA) will host (2001-09-21)

Response to first drug treatment may signal likelihood of future seizures in people with epilepsy
How well people with newly diagnosed epilepsy respond to their first drug treatment, may signal the likelihood that they will continue to have uncontrolled seizures according to University of Melbourne Chair of Neurology Professor Patrick Kwan. (2012-05-09)

Study says drugs could be developed cheaper and faster
Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could revolutionize drug development, and substantially reduce the cost and time drugs need to reach their market. (2017-02-22)

Nanoparticle reduces targeted cancer drug's toxicity
In one of the first efforts to date to apply nanotechnology to targeted cancer therapeutics, researchers have created a nanoparticle formulation of a cancer drug that is both effective and nontoxic -- qualities harder to achieve with the free drug. (2016-02-10)

Chemical Biology & Drug Design. A new face, a new title, a new vision
From 2006, Tomi K Sawyer will take command of Chemical Biology & Drug Design, a significant re-launch of the internationally acclaimed Journal of Peptide Research. The newly entitled journal will have a revised aims and scope reflecting the evolving multidisciplinary fields of chemical biology and drug design, and a significantly expanded editorial team of world class academic and industrial scientists. (2005-10-03)

Lessons from Vioxx case -- New approach needed to restore faith in pharmaceutical industry
The pharmaceutical industry, academia and government agencies need to work together to restore faith in drug development, say doctors in this weeks' BMJ. They argue that the recent litigation over the drug Vioxx, produced by Merck and Co. Inc., has highlighted the failings of the current system, which can be open to abuse. (2007-01-19)

Asia must tackle HIV in injecting drug users
Asian countries must adopt strategies to slow the spread of HIV among injecting drug users, urge researchers in this week's BMJ. (2004-09-23)

Transmission of drug-resistant HIV-1
Drug-resistant forms of HIV can be spread between individuals who have not received anti-retroviral treatment, according to Professor Deenan Pillay from University College, London and the Health Protection Agency, speaking at the Society for General Microbiology meeting at Harrogate Monday, March 30. (2009-03-29)

RUDN biochemists found out how ROS affect cisplatin resistance in ovarian cancer cells
A team of sciences from RUDN Institute of Medicine found out how reactive oxygen species affect the resistance of ovarian cancer cells to chemotherapy on the example of cisplatin -- an antitumor drug used to treat this type of malignant growth. Practical application of the research results would help improve medical treatment schemes for cancer patients. The article of the scientists was published in the materials of FEBS Congress (FEBS Open Bio). (2018-09-13)

Doping, sport and the community
On the eve of the Olympics, Dr. Andrew Pipe asks whether we succeeded in addressing drug doping and its public health ramifications. (2008-08-11)

Novel anti-cancer drug, ONC201, focus of alliance between Oncoceutics and MD Anderson
Oncoceutics Inc. and the University of Texas MD Anderson Cancer Center today announced the initiation of a strategic alliance and research collaboration agreement for the clinical development of ONC201, a novel anti-cancer drug. (2015-01-05)

Finger prick test allows patients taking autoimmune drug to avoid blood draws
A new study shows that patients with rheumatoid arthritis and other autoimmune conditions who take the drug adalimumab can monitor drug levels in their bodies with a finger prick rather than undergoing a full blood draw. (2017-08-09)

Could a diabetes drug be used for Motor Neurone Disease?
A diabetes drug could one day be used to treat neurodegenerative diseases like Motor Neurone Disease (MND), Alzheimer's and Parkinson's. Researchers at Lancaster University are to conduct a clinical trial of the diabetes drug Liraglutide, giving it to patients with MND to see whether they improve or not. (2017-03-10)

Yale research program on women and drug abuse established with $2.5 million NIDA grant
Drug abuse among women will be the focus of a new five-year, $2.5 million grant recently awarded to Yale University researchers in the Department of Psychiatry. The grant, funded by the National Institute on Drug Abuse and the National Institutes of Health Office of Research on Women's Health, will train scholars to conduct interdisciplinary research on the etiology of drug abuse in women, and on the development of new sex-specific treatments and prevention strategies. (2000-11-13)

New hope for malaria treatment as drug resistance found unable to spread for the first time
Resistance to a key anti-malarial drug cannot be passed on by mosquitoes in a breakthrough scientists believe could drastically improve the way we battle the disease. (2016-04-14)

Adverse drug reactions may be under-reported in young children
A new study reveals that adverse drug reactions in newborns and infants may be under-reported. (2016-09-07)

Prescription drug expenses in Canada are a health-care barrier
High drug expenses in Canada are a substantial barrier for people to access prescription drugs outside of hospital, states an analysis in CMAJ. (2013-09-16)

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