Estrogen Current Events

Estrogen Current Events, Estrogen News Articles.
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Battling breast cancer
In an upcoming issue of Genes & Devolpment, Dr. Myles Brown and colleagues lend new insight into the transcriptional network that drives breast cancer cell proliferation in response to estrogen exposure. (2006-09-14)

Menopausal hormone therapy and breast cancer risk
In the past decade, results from large prospective cohort studies and the Women's Health Initiative randomized placebo-controlled hormone therapy trials have substantially changed thoughts about how estrogen alone and estrogen plus progestin influence the risk of breast cancer, according to a review published March 15 in the Journal of The National Cancer Institute. (2012-03-15)

U of MN researchers discover novel way estrogen affects the brain
University of Minnesota researchers have demonstrated how estrogen affects learning and memory. They found that estrogen can activate particular glutamate receptors within the hippocampus, the brain region responsible for many aspects of learning and memory. (2005-05-19)

Some breast cancer patients may benefit from endocrine therapy alone
The estrogen receptor status of breast cancer may help to predict which patients will benefit from chemotherapy treatment, say researchers at The University of Texas M. D. Anderson Cancer Center. (2003-12-04)

Hopkins study shows combined hormone therapy increases muscle, decreases fat in postmenopausal women
A combined hormone therapy of estrogen and androgen may improve body composition in postmenopausal women, according to results of a Johns Hopkins study to be presented at 1 p.m., June 12, at ENDO 99, the 81st annual meeting of The Endocrine Society in San Diego. (1999-06-13)

More research needed to gauge estrogen's effects on Alzheimer's disease, Yale scientists say
In response to a new study showing that estrogen does not slow the effects of Alzheimer's disease, Yale researchers say more studies are needed to answer key questions about estrogen's possible role in preventing or delaying the disease. (2000-02-21)

Estrogen not associated with lung cancer incidence and mortality among postmenopausal women
Use of estrogen alone did not increase lung cancer mortality in postmenopausal women, according to a study published online Aug. 13 in the Journal of the National Cancer Institute. (2010-08-13)

Scientists identify molecular link between estrogen receptors and invasive growth in breast cancer
Emory University and Winship Cancer Institute Scientists have discovered a link between estrogen receptors -- the molecules that bind the estrogen hormone to cells -- and invasive growth of breast cancer. The finding could help explain the mechanisms leading to breast cancer progression and could have important consequences for drugs that are aimed at blocking estrogen receptors. (2003-04-17)

Estrogen curbs appetite in same way as the hormone leptin
Estrogen regulates the brain's energy metabolism in the same way as the hormone leptin, leading the way to a viable approach to tackling obesity in people resistant to leptin, researchers at Yale School of Medicine report in the Dec. 31 online issue of Nature Medicine. (2007-01-03)

Hormone mix could cut breast cancer risk and treat symptoms of menopause
The right combination of estrogen and a selective estrogen receptor modulator, which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk, Yale researchers report in an abstract presented at the American Society for Reproductive Medicine scientific meeting in Atlanta, Ga., Oct. 17-21. (2009-10-19)

Estrogen interferes with immune surveillance in breast cancer
Estrogen is known to enhance the growth and migration of breast cancer cells. Now researchers at the University of Illinois at Urbana-Champaign have found that estrogen also can shield breast cancer cells from immune cells. This is the first study to identify estrogen's role in shielding breast cancer cells from the action of immune cells. (2007-01-24)

UB Researcher To Conduct First Study Of Possible Link Between Prostate Cancer And Estrogen Metabolism
The first investigation of the role of estrogen metabolism in the development of prostate cancer will begin at the University at Buffalo in October, funded by a $450,000 grant from the U.S. Army's Medical Research and Material Command. The study will determine if differences in estrogen metabolism exist between healthy men and men who develop prostate cancer. (1998-05-04)

Mayo Clinic news briefs
A Mayo Clinic study analyzing coronary calcium and plaque found that estrogen may slow the progression of atherosclerosis in women. (2002-03-13)

Women's natural estrogen levels help protect against cognitive decline, UCSF/VA study says
Older women with high estrogen levels are less likely to suffer cognitive decline, says a new study from researchers at the University of California, San Francisco and the San Francisco Veterans Affairs Medical Center. (2000-08-23)

Continuous joint use of estrogen and progestin lowers risk of EC in postmenopausal women
Adding continuous progestin to estrogen has been shown to lower the risk of endometrial cancer in postmenopausal women according to a study published Dec. 14 in the JNCI: Journal of the National Cancer Institute. (2015-12-14)

UK researchers find critical link for estrogen's neuroprotective effects
University of Kentucky College of Medicine researchers have determined that one specific estrogen receptor, called ERa, is a critical link in mediating the protective effects of estradiol in brain injury. (2001-02-11)

Estrogren plus progestin decreases colorectal cancer in postmenopausal woman
Estrogren plus progestin decreases colorectal cancer in postmenopausal woman, according to an article by Rowan Chlebowski, MD, PhD, a principal investigator at the Research and Education Institute at Harbor-UCLA Medical Center. (2004-03-03)

Drs. Brann and Mahesh co-edit journal issue on estrogen action in the brain
Estrogen's action in the brain is the focus of a special August issue of Molecular and Cellular Endocrinology co-edited by Dr. Darrell W. Brann, Regents Professor of Neurology and associate director of the Institute of Neuroscience at the Medical College of Georgia. (2008-08-06)

Estrogen Use May Reduce Risk Of Alzheimer's Disease
A study from Johns Hopkins and the National Institute on Aging (NIA) adds more eidence that women who use estrogen appear to have less risk of developing Alzheimer's disease (AD). (1997-06-18)

Estrogen may play role in prevention of cataracts
Indiana University School of Medicine researchers have shown that optic lens cells may be added to the growing list of parts of the body found to be sensitive to the hormone estrogen. Lens cells have receptors for estrogen, adding further evidence to epidemiological research showing that estrogen may play a role in preventing cataracts in aging woman. (1999-10-06)

When a KISS (1) goes bad
KISS 1 is a metastasis-suppressor gene which helps to prevent the spread of cancers, including melanoma, pancreatic and ovarian cancers to name a few. But new research from Western University's Schulich School of Medicine & Dentistry shows that kisspeptins -- peptide products of KISS1, actually make some breast cancers worse, with a higher tumor grade and metastatic potential. The research is published online in the journal Endocrinology. (2013-04-16)

Estrogen Benefits The Eyes, Study Shows
While estrogen's ability to prevent bone loss and heart disease in postmenopausal women is established, here's something new: estrogen may benefit the eyes. A study in the June issue of Ophthalmology found a reduced incidence of lens opacities, precursors of age-related cataract, in postmenopausal women taking estrogen (1997-06-11)

Celecoxib shows surprising activity against estrogen receptors
Six months of treatment with celecoxib (Celebrex) in women at risk of developing breast cancer results in the reduction of estrogen receptor expression in breast cells, a research team at The University of Texas M. D. Anderson Cancer Center has found. (2004-12-10)

UW study to clarify safety, effectiveness of hormone therapy during menopause
When is the best time in a woman's reproductive history to start hormone therapy? How does estrogen therapy affect a woman's cognition and mood? What is the most beneficial form of estrogen? (2007-05-22)

UF Health researchers use gene therapy to extend estrogen's protective effects on memory
The hormone estrogen helps protect memory and promote a healthy brain, but this effect wanes as women age, and even estrogen replacement therapy stops working in humans after age 65. Now researchers at University of Florida Health have used gene therapy in a rat model to show that the expression of a particular receptor can reinstate lost memory function. (2015-12-08)

Progestin in oral contraceptives associated with lower risk of ovarian cancer
Oral contraceptives -- better known as birth control pills -- that contain high levels of progestin are associated with a lower risk of ovarian cancer than oral contraceptives with low progestin content, concludes a study in the Jan. 2 issue of the Journal of the National Cancer Institute. (2002-01-01)

AACR news: Studies show increasing evidence that androgen drives breast cancer
Estrogen and progesterone receptors, and the gene HER2 -- these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: Androgen receptors. (2013-04-10)

Scott & White Healthcare pathologist is co-investigator on breast cancer study
In a laboratory study published in the journal Cancer Research, Scott & White Healthcare anatomic pathologist Arundhati Rao, M.D., is a co-investigator looking at the ways in which estrogen can interfere with how chemotherapy does its job in destroying breast cancer cells. (2010-02-23)

Estrogen plus progestin use linked with increased breast cancer incidence and mortality
Estrogen plus progestin use is linked with increased breast cancer incidence. In addition, prognosis is similar for both users and nonusers of combined hormone therapy, suggesting that mortality from breast cancer may be higher for hormone therapy users as well, according to a study published Mar. 29 in the Journal of the National Cancer Institute. (2013-03-29)

The sneaky way estrogen drives brain metastasis in non-estrogen-dependent breast cancers
University of Colorado Cancer Center study shows that while estrogen doesn't directly affect triple-negative breast cancer cells, it can affect surrounding brain cells in ways that promote cancer cell migration and invasiveness (2019-03-01)

Survey Shows Women Need To Know More About Estrogen Therapy
Many menopausal and post-menopausal women are not getting all the information they need or want on estrogen-replacement therapy, according to a new study. As a result, they may be missing out on potential benefits from taking estrogen, like a lower risk of heart disease and osteoporosis. (1998-11-02)

Estrogen or stimulating environment boost memory
Estrogen treatment had less beneficial effect on memory in female mice that raced on running wheels and played with other toys than in mice raised in non-stimulating environments. (2004-10-22)

Dr. Rowan Chlebowski: Effects of estrogen alone vs. estrogen plus progestin on breast cancer risk
In the past decade, results from large prospective cohort studies and the Women's Health Initiative (WHI) randomized placebo-controlled hormone therapy trials have substantially changed thoughts about how estrogen alone and estrogen plus progestin influence the risk of breast cancer. To compare, LA BioMed investigator Rowan T. Chlebowski, M.D., Ph.D., and Garnet Anderson, Ph.D., at Fred Hutchinson Cancer Research Center, looked at data from two randomized, placebo-controlled full scale clinical trials conducted in the WHI. (2012-03-15)

Estrogen improves short term memory and oral reading in midlife postmenopausal women
Midlife postmenopausal women who received daily treatment with estrogen showed improved oral reading and verbal memory performance, Yale School of Medicine researchers report in the September issue of the journal Menopause. (2003-09-23)

How estrogen feeds breast tumors
A new study is providing insight into how estrogen fuels many breast cancers, and researchers say the findings could lead to new cancer-fighting drugs. (2010-03-02)

Estrogen helps keep joint pain at bay after hysterectomy
Estrogen therapy can help keep joint pain at bay after menopause for women who have had a hysterectomy. Joint pain was modestly, but significantly, lower in women who took estrogen alone than in women who took placebo in the Women's Health Initiative trial. The findings were published online today in Menopause, the journal of The North American Menopause Society. (2013-03-20)

Mayo Clinic study finds definitive evidence relating to the role of estrogen in elderly males
A Mayo Clinic study, published in the December edition of the Journal of Clinical Investigation, provides new evidence that estrogen is dominant in the regulation of bone resorption in elderly men. Based on the study conclusions, men also need to be concerned about the long-term effects of bone loss, or osteoporosis. (2000-12-12)

DACH1 a key protein for tumor suppression in ER+ breast cancer
Researchers from the Kimmel Cancer Center at Jefferson have identified a protein relationship that may be an ideal treatment target for ER+ breast cancer. The study was reported in the July 15 issue of Cancer Research. (2009-07-15)

Team discovers new inhibitors of estrogen-dependent breast cancer cells
Researchers have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. The finding, described today at a meeting of the Endocrine Society, has opened an avenue of research into new drugs to combat estrogen-dependent breast cancers. (2008-06-16)

Estrogen fluctuation affects epileptic seizures
A Northwestern University scientist reports that understanding how estrogen contributes to seizure activity could lead to novel and needed therapeutic targets for anti-epileptic drugs. (2007-04-30)

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