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Fibroblasts Current Events, Fibroblasts News Articles.
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Rejuvenated fibroblasts can recover the ability to contract
A recent study from the Mechanobiology Institute at the National University of Singapore has shown that rejuvenated fibroblasts can recover their ability to self-contract. (2020-05-26)
Study reveals disparity between fibroblasts of different pancreatic diseases
Fibroblasts present in different pancreatic diseases are genetically distinct and their functions are 'programmed' by the unique environment of each disease, according to new research from the University of Liverpool (UK). (2020-05-18)
New technique may help regenerate heart cells to treat heart disease
Researchers have developed a new technique that might one day be used to convert cells from heart disease patients into heart muscle cells that could act as a personalized treatment for their condition. (2013-08-22)
Muscle-derived stem cell culture doesn't need to be pure for incontinence treatment
A pure culture of muscle-derived stem cells (MDC) may not be needed to cure stress urinary incontinence, according to a University of Pittsburgh study. (2005-05-23)
Boring cells could hold the key to heart disease
Fibroblasts, cells long thought to be boring and irrelevant, could offer an alternative to heart transplants for patients with heart disease. (2014-04-24)
Breast cancer recruits bone marrow cells to increase cancer cell proliferation
Tel Aviv University researchers have discovered that breast cancer tumors boost their growth by recruiting stromal cells that originate in bone marrow. (2018-12-10)
Fibroblasts hold clues to fat, scars and inflammation
Scientists used to think that fibroblasts - the cells that form basic tissue structures - were little more than scaffolding on which more important cells would climb. (2003-09-25)
Leukemia drug reverses tamoxifen-resistance in breast cancer cells
Taking a leukemia chemotherapy drug may help breast cancer patients who don't respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests. (2011-08-01)
Breast cancers enhance their growth by recruiting cells from bone marrow
Researchers in Israel have discovered that breast tumors can boost their growth by recruiting stromal cells originally formed in the bone marrow. (2018-11-23)
Syndecan-4 regulates wound repair in vivo
Cell surface heparan sulfate proteoglycans (HSPG) can be divided generally into two gene families: syndecans and glypicans. (2001-01-09)
Anti-inflammatory drug is the key to boosting cardiac reprogramming
University of Tsukuba researchers and colleagues developed a high-throughput screening system to identify the NSAID diclofenac as a factor responsible for enhancing cardiac reprogramming in postnatal and adult fibroblasts. (2019-03-06)
When healthy cells stimulate the migration of tumor cells
Estrogens act as a driving force of both healthy and cancerous mammary cell growth by binding to receptors that include GPER, which is generally located in cell membranes. (2017-06-15)
Scientists have identified the presence of cancer-suppressing cells in pancreatic cancer
Researchers have identified cells containing a protein called Meflin that has a role in restraining the progression of pancreatic cancer. (2019-10-07)
Fibroblasts contribute to melanoma tumor growth, say Moffitt Cancer Center researchers
Fibroblasts, cells that play a role in the structural framework of tissues, play an apparent role in melanoma tumor growth. (2012-01-05)
Fibroblasts invade at a snail's pace
A transcription factor known to drive the formation of fibroblasts during development also promotes their ability to invade and remodel surrounding tissues, report Rowe et al. (2009-02-02)
Blocking the molecular source of idiopathic pulmonary fibrosis
Successfully tested in mice, targeted drug and gene therapies might one day benefit patients with a deadly lung disease, new U-M research finds. (2018-05-08)
Fibroblasts involved in healing spur tumor growth in cancer
The connective tissue cells known as fibroblasts are vitally important for our recovery from injury. (2019-12-19)
Study first to link mitochondrial dysfunction and alpha-Synuclein multiplication in human fibroblasts
A new study in the Journal of Parkinson's Disease shows for the first time the effects of alpha-Synuclein gene multiplication on mitochondrial function and susceptibility to oxidative stress in human tissue. (2011-10-06)
A built-in source for new heart cells
In heart disease, cardiac muscle gradually dies off and, with little or no way to regenerate those cells, that can ultimately lead the heart to fail. (2010-08-05)
Rensselaer researcher wins prestigious American Cancer Society award for work on cancer
A recent Research Scholar Grant from the American Cancer Society acknowledges the potential of Rensselaer researcher Lee Ligon's work on breast cancer. (2010-10-14)
IDIBELL -- ICO researchers set new bases to develop therapies against colorectal cancer
IDIBELL -- ICO researchers in Barcelona have found that inactivation of two proteins make tumoral cells more sensitive to chemotherapy. (2019-04-17)
Novel mechanism through which normal stromal cells become cancer-promoting cells identified
Change in three microRNAs' expression converted normal fibroblasts to cancer-associated fibroblasts. (2012-11-21)
Protein associated with allergic response causes airway changes in asthma patients
Changes that occur in the airways of asthma patients are in part caused by the naturally occurring protein interleukin-13 (IL-13) which stimulates invasion of airway cells called fibroblasts, according to a study conducted by researchers at Duke University. (2011-03-22)
Missing molecule hobbles cell movement
Cells are the body's workers, and they often need to move around to do their jobs. (2019-05-03)
Mechanism for esophageal cancer uncovered
A gene thought to be associated with cancer development can be a tumor suppressor gene in mice, researchers have discovered. (2011-04-11)
Process for expansion and division of heart cells identified
Researchers at the Gladstone Institute of Cardiovascular Disease and the University of California, San Francisco have unraveled a complex signaling process that reveals how different types of cells interact to create a heart. (2009-02-17)
Skin ages when the main cells in the dermis lose their identity and function
A study in mice done at IRB Barcelona and CNAG-CRG explains that dermal fibroblasts lose their cell identify over time and with it their capacity to produce and secrete collagen and other proteins. (2018-11-08)
Establishment of induced pluripotent stem cells from Werner syndrome fibroblasts
Induced pluripotent stem (iPS) cells from Werner Syndrome fibroblasts have been established. (2014-11-18)
New understanding of how cells form tunnels may help in treating wounds, tumors
'A major aspect of our research is that it just really illustrates how complex all these different components are going on inside a person's body,' said Andrew Ford. (2019-05-23)
An unholy alliance -- Colon cancer cells in situ co-opt fibroblasts in surrounding tissue to break out
In work to be presented at the ASCB/IFCB meeting in Philadelphia, researchers from the Institut Curie in Paris report that they have evidence of a coordinated attack on the basement membrane of human colon cells by cancer cells in situ and CAF cells in the extracellular matrix that begins long before the actual translocation of cancer cells. (2014-12-05)
Biologists uncover surprising connection between breast cancer cells and surrounding tissue
Rensselaer Polytechnic Institute Biologist Lee Ligon has found a previously unknown connection between breast cancer tumor cells and the surrounding healthy tissue. (2012-03-14)
MicroRNAs can convert normal cells into cancer promoters
Ovarian cancer cells use three microRNAs to convert normal, healthy cells into cancer-associated fibroblasts. (2012-11-21)
UC San Diego researchers identify how skin ages, loses fat and immunity
Some dermal fibroblasts can convert into fat cells that reside under the dermis, giving skin a youthful look and producing peptides that fight infections. (2018-12-26)
Immune cells help reverse chemotherapy resistance in ovarian cancer
New research explains why ovarian cancer becomes resistant to chemotherapy. (2016-05-20)
Cigarette smoke a culprit in poor healing and increased scarring
Cigarette smoke, whether first- or second-hand, complicates the careful cellular choreography of wound healing, according to a paper by University of California, Riverside researchers that was included in the 2004 Press Book of the 44th Annual Meeting of the American Society For Cell Biology (ASCB). (2004-12-06)
New mechanical insights into wound healing and scar tissue formation
New research published today in the Journal of Cell Biology illuminates the mechanical factors that play a critical role in the differentiation and function of fibroblasts, connective tissue cells that play a role in wound healing and scar tissue formation. (2007-12-17)
Cells' steering wheel
A new mechanism clarifies how cells migrate. (2016-08-22)
Turning cells against pancreatic cancer
Pancreatic cancer is infamously resistant to treatment options because the tumor is often surrounded by cells which are ''tricked'' into protecting it. (2018-10-26)
Recapitulation of the entire hepatitis C virus life in engineered mouse cell lines
A US study presented today at the International Liver Congress 2012 demonstrates that the entire HCV lifecycle can be recapitulated in murine cells, implying that HCV permissive mouse models could soon be developed. (2012-04-19)
UNC researchers boost the heart's natural ability to recover after heart attack
UNC researchers discovered that fibroblasts, which normally give rise to scar tissue after a heart attack, can be turned into endothelial cells, which generate blood vessels to supply oxygen and nutrients to the injured regions of the heart, greatly reducing the damage done following heart attack. (2014-10-15)
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