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Gene Expression Current Events, Gene Expression News Articles.
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Novel technique reveals both gene number and protein expression simultaneously
Researchers have discovered a method to simultaneously measure gene number and protein expression in individual cells. (2011-09-22)
Researchers get a closer look at how the Huntington's gene works
A closer look at the DNA around the Huntington's disease gene offers researchers a new understanding of how the gene is controlled and how this affects the disease. (2015-05-04)
Persistent gene therapy in muscle may not require immunosuppression
In this issue of the Journal of Clinical Investigation, Christian Mueller and colleagues at the University of Massachusetts Medical School evaluated the persistence of rAAV-mediated expression the gene encoding M-type α-1 antitrypsin in patients that were AAT deficient (2013-11-15)
Can male prairie voles blame promiscuity on poor memory?
Male prairie voles that roam widely looking for mates have poorer spatial memory than their faithful male counterparts, who better recall locations of rough encounters with other males and thus stay closer to home, a new study shows. (2015-12-10)
Roles of S100A2 and p63 in the carcinogenesis of esophageal squamous cell carcinoma
S100A2 is considered a candidate tumor-suppressor gene. Recently, p63 gene, a new member of the p53 gene family, has been studied in the fields of tumorigenesis, cell apoptosis and tissue growth. (2009-09-16)
New nanotechnology able to examine single molecules, aiding in determining gene expression
A new nanotechnology that can examine single molecules in order to determine gene expression, paving the way for scientists to more accurately examine single cancer cells, has been developed by an interdisciplinary team of researchers at UCLA's California Nanosystems Institute, New York University's Courant Institute of Mathematical Sciences, and Veeco Instruments, a nanotechnology company. (2007-01-24)
Consistency is the key to success in bread baking and biology
Whether you're baking bread or building an organism, the key to success is consistently adding ingredients in the correct order and in the right amounts, according to a new genetic study by University of Michigan researchers. (2015-03-16)
City of Hope links specific gene to adult growth of brain cells, learning and memory
Learning and memory are regulated by a region of the brain known as the hippocampus. (2014-06-09)
Function follows form in developing myocytes
Cells undergo complex changes in morphology and gene expression as they differentiate, but the relationship between these changes has long been obscure, with hints that cell shape per se can control cellular patterns of gene expression in some cases. (2000-11-28)
BGRF announces OncoFinder algorithm for reducing errors in transcriptome analysis
The BGRF proposes a new concept for signalome-wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data. (2014-08-17)
UofL researchers replicate human kidney gene changes in mouse model
University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according to an article published today in the journal Experimental Nephrology. (2011-05-23)
Researchers find an evolutionarily preserved signature in the primate brain
Researchers have determined that there are hundreds of biological differences between the sexes when it comes to gene expression in the cerebral cortex of humans and other primates. (2008-06-19)
Chronic fatigue -- clues in the blood
Researchers at the University of New South Wales believe that blood may hold vital insights into what is happening in the brain of patients with chronic fatigue syndrome (CFS). (2007-07-06)
Collisions during DNA replication and transcription contribute to mutagenesis
Replication-transcription head-on collisions contribute to mutagenesis. (2016-06-29)
Helping cancer researchers make sense of the deluge of genetic data
A web tool helps cancer researchers and physicians make sense out of a deluge of genetic data from nearly 100,000 patients and more than 50,000 mice. (2013-12-12)
Individuals and populations differ in gene activity levels, not just genes
Much like how a person's genetic code differs from other individuals, the level at which those genes are activated in the body differs from one person to another, scientists have learned. (2007-03-01)
CNIO scientists link aggressiveness of chronic lymphocytic leukemia to genetic variability
The two subtypes of this kind of leukemia, mutated and non-mutated, show different levels of aggressiveness and are closely related to the genetic variability amongst individuals. (2015-02-05)
Mobile DNA elements can disrupt gene expression and cause biological variation, study shows
The many short pieces of mobile DNA that exist in the genome can contribute to important biological differences between strains of mice, according to a new study. (2012-02-23)
UTMB scientist awarded $150,000 by March of Dimes
The March of Dimes Foundation has chosen University of Texas Medical Branch at Galveston assistant professor Muge Kuyumcu-Martinez to receive a two-year, $150,000 Basil O'Connor Starter Scholar Award. (2012-04-20)
Clocking salt levels in the blood: A link between the circadian rhythm and salt balance
New research, to be published in the Journal of Clinical Investigation, suggests a link between the circadian rhythm and control of sodium (salt) levels in the blood of mice. (2009-07-01)
Biologists uncover regulatory mechanism for gene expression in the visual system
Biologists have uncovered a key regulatory mechanism used for gene expression in the visual system. (2011-06-09)
Researchers identify a new gene with a key role in obesity and diabetes
An international team of scientists this week announced in Nature Medicine that they have identified a gene which regulates fat metabolism and is involved in the onset of obesity and related metabolic disorders like type 2 diabetes. (2013-01-10)
A genetic polymorphism associated with lung cancer progression
Researchers at the Hiroshima University and Saitama Medical University found that in patients with lung cancer, a single nucleotide polymorphism may regulate gene and protein expression and be associated with poor prognosis. (2015-10-05)
'Smart' bacteria remodel their genes to infect our intestines
How pathogens establish themselves in our gut is poorly understood. (2017-02-22)
Other highlights in the April 3 issue of JNCI
Other highlights include studies that identify a tumor suppressor gene for prostate cancer and a marker of progression of colon cancer, a study that looks at the effects of depsipeptide in lung cancer cells, and a study that looks at the cancer-specific expression of the survivin promoter. (2002-04-02)
Diagnostic breakthrough for Burkitt lymphoma reported in NEJM
An international research study involving numerous institutions has successfully identified the gene expression signature for Burkitt lymphoma. (2006-06-09)
Medication improves obesity-associated gene expression in mice
This week in the JCI, research led by Mitch Lazar at the Perelman School of Medicine at University of Pennsylvania shows that rosiglitazone, an a diabetes medication, corrects alterations in gene expression in the fat cells of obese mice. (2017-02-27)
A small cut with a big impact
During inflammation, controlled gene expression is necessary in order to allow the organism to mount an effective defense response. (2012-05-02)
Manipulating gene expression precisely using light
A scientist has developed a new method to accurately manipulate gene expression by light illumination and demonstrated its usability by creating double-headed zebrafish. (2017-01-23)
Science researchers report 'extremely unstable' gene expression in cloned mice
Extremely unstable gene expression in mice cloned from embryonic stem cells may shed light on why cloning is such an inefficient process. (2001-07-05)
Steps that lead to genes being switched on revealed in atomic simulation
Researchers have modelled every atom in a key part of the process for switching on genes, revealing a whole new area for potential drug targets. (2016-05-13)
Researchers achieve germline transmission of 'gene knockdown' in mice
RNA interference (RNAi) has emerged as a powerful tool in biomedical research. (2003-01-19)
Linking gene expression and DNA methylation in single cells
A new single-cell genomics protocol allows researchers to study links between DNA modifications (methylation) and the activity of a gene. (2016-01-11)
Mechanism sheds light on how the brain adapts to stress
Scientists now have a better understanding of the way that stress impacts the brain. (2012-01-25)
Clustering gene expression changes reveals pathways toward glaucoma prevention
Using a method that involved the clustering of samples that showed similarity in expression profiles, Jackson Laboratory researchers were able to identify molecular signatures of early events in glaucoma progression -- events that were detectable before there was morphological evidence of damage. (2011-03-07)
Jefferson scientists find gene expression pattern may predict behavior of leukemia
The expression pattern of certain genes may someday help doctors to diagnose and predict whether or not an individual has an aggressive form of B-cell chronic lymphocytic leukemia (CLL), Jefferson cancer researchers have found. (2004-08-10)
Nine-gene MPI can provide accurate survival stratification in patients with NSCLC
A nine-gene molecular prognostic index for patients with early-stage non-small cell lung cancer was able to provide accurate survival stratification and could potentially inform the use of adjuvant therapy in patients struggling with the disease, according to a study published Aug. (2015-08-18)
Tolerance to inhalants may be caused by changes in gene expression
Changes in the expression of genes may be the reason why people who abuse inhalants, such as spray paint or glue, quickly develop a tolerance, biologists at The University of Texas at Austin have discovered. (2007-10-17)
FASEB Science Research Conference: Mechanism and Regulation of Prokaryotic Transcription
This SRC will focus on the process of transcription in prokaryotes, from structure/function investigations to transcription networks and system level regulation. (2017-02-28)
Silence of the amoebae
Three years ago, scientists at the Weizmann Institute accidentally discovered a way to silence the expression of a key amoebic gene, one which codes for a toxic protein that kills human intestinal cells infected with this devastating illness. (2006-08-30)
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