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Gene Expression Current Events, Gene Expression News Articles.
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Compound regulates genetic risk factor in Parkinson's disease
Suchi Mittal and colleagues have identified beta-2 adrenergic receptor (β2AR) agonists as compounds that can reduce levels of the alpha-synuclein gene, which has been implicated in increased risk for Parkinson's disease. (2017-08-31)
First step towards detecting exposure to biowarfare agents
Army researchers are laying the groundwork for what one day could be a test to identify individuals who have been exposed to biological agents. (2003-03-11)
BUSM study investigates genetic variants' role in increasing Parkinson's disease risk
Boston University School of Medicine investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). (2012-10-05)
How a fish can fry: Scientists uncover evolutionary clues behind electric fish
Take a muscle cell, modify it over millions of years, and you end up with an exciting and literally shocking evolutionary result: the electric fish.The authors speculate that the down-regulation of the Scn4aa gene leads to quicker evolution and adaptation. (2014-04-29)
Consortium seeks comment on gene expression roadmap
The External RNA Controls Consortium (ERCC) has issued for comment a draft plan for the selection and qualification of candidate RNA sequences, to be used as controls for assessing the performance of gene expression experiments. (2005-08-30)
Scientists identify genetic link between cancer and aging
A collaboration of scientists mainly from the Fred Hutchinson Cancer Center and at the University of Washington (Seattle) has made an important discovery linking the powerful cancer-causing oncogene, myc, with the gene behind the premature aging disease, Werner syndrome. (2003-06-23)
Gene expression patterns may help predict risk and progression of prostate cancer
According to a study published in the July 15 issue of the Journal of Clinical Oncology, genes expressed in benign tissue adjacent to prostate cancer tissue are much more similar to prostate cancer tissue than previously thought. (2004-07-15)
Inherited DNA change explains overactive leukemia gene
A small inherited change in DNA overactivates a gene linked to poor treatment response in people with acute leukemia. (2012-05-25)
UI findings indicate DNA methylation process may lead to oral cancer
Just like a light switch, a process known as cytosine methylation can turn off expression of tumor suppressor genes and lead to oral cancer, according to University of Iowa Health Care research findings. (1999-10-04)
Study sheds new light on relationship between personality and health
Researchers have found new evidence that explains how some aspects of our personality may affect our health and wellbeing, supporting long-observed associations between aspects of human character, physical health and longevity. (2014-12-11)
Fox Chase researchers uncover one force behind the MYC oncogene in many cancers
DLX5, a gene crucial for embryonic development, promotes cancer by activating the expression of the known oncogene, MYC, according to researchers from Fox Chase Cancer Center. (2009-07-28)
Simultaneous live imaging of a specific gene's transcription and dynamics
A Japanese research group has developed a live-imaging method for simultaneous measurements of the transcriptional activity and nuclear position of endogenous genes. (2015-06-18)
News tips from The Journal Of Neuroscience
In this issue, Gabel et al. report that FMRP expression is dynamically regulated in vivo in dark-reared, light-exposed rats. (2004-11-23)
Study finds key mechanism important for sex determination in vertebrates
In various vertebrate species, including fish, amphibians, reptiles, birds and mammals, the DMRT1 gene is a master sex regulator. (2016-12-06)
Researchers discover new approach for identifying smokers at highest risk for developing lung cancer
Researchers from Boston University School of Medicine in collaboration with investigators at the University of Utah, have discovered a new approach for identifying smokers at the highest risk for developing lung cancer. (2010-04-07)
Mapping a model: International research on plant species appears in journal Nature
Two Kansas State University researchers have been collaborating on an international project involving genomes of Arabidopsis thaliana, a model plant species that can offer insights into other plants. (2011-09-01)
Researchers distinguish new type of leukemia
HHMI researchers who have studied the activity of thousands of genes in a drug-resistant form of childhood leukemia are now proposing that the disease be called mixed-lineage leukemia because it is a distinct disease, and not a subtype of the more prevalent acute lymphoblastic leukemia. (2001-12-03)
After almost a century, a question answered; genes protect themselves against being silenced
Harvard Stem Cell Institute researchers have settled a century-old debate over whether occurrence of DNA methylation acts to silence gene expression, or if genes are turned off by other means before they are methylated. (2013-10-10)
Why does anxiety target women more? FSU researcher awarded $1.8 million grant to find out
Anxiety disorders afflict women twice as often as men, but estrogen might not be the reason. (2010-09-01)
Gene expression in the aging brain
In a paper published in the open access journal PLoS Biology, transcriptional profiles in human and chimpanzee reveal a diversity of aging patterns present within the human brain, as well as how rapidly genome-wide patterns of aging can evolve between species. (2005-08-01)
Study challenges long-held assumption of gene expression in embryonic stem cells
Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in maintaining the self-renewal of embryonic stem cells, is expressed in a manner similar to other pluripotency markers. (2013-07-03)
Clue to unusual drug-resistant breast cancers found
Researchers at the University of Illinois at Chicago College of Medicine have found how gene expression that may contribute to drug resistance is ramped up in unusual types of breast cancer tumors. (2010-10-08)
Genetics of muscular dystophy
Various forms of human muscular dystrophy result from mutations in genes encoding proteins of the nuclear envelope. (2006-02-14)
A new application allows online statistical analysis of gene-expression data
The journal Computers in Biology and Medicine has published an article on the new IT application BootstRatio, created by IDIBELL researchers. (2012-04-03)
Jefferson researchers develop microchip to track genetic signature of cancer and normal tissue
MicroRNAs (miRNAs), tiny pieces of genetic material that can serve as stop signs for gene expression and protein synthesis, are thought to be important in the development of cancer. (2004-06-22)
New tool probes function of rice genes
A new tool for investigating the rice genome has been developed by researchers at UC Davis led by Pamela Ronald, professor of plant pathology. (2008-10-08)
American Society for Microbiology honors Marvin Whiteley
A 2008 American Society for Microbiology Merck Irving S. Sigal Memorial Award is being presented to Marvin Whiteley, Assistant Professor, Molecular Genetics and Microbiology, University of Texas at Austin. (2008-07-16)
Search tool for gene expression databases could uncover therapeutic targets, biological processes
A new computational tool developed by US and Israeli scientists will help scientists exploit the massive databases of gene expression experimental results that have been created over the past decade. (2013-10-01)
Expression of a 'Ouija Board' protein that can summon 'monster' genes
A research group led by University of Tsukuba Faculty of Life and Environmental Sciences Associate Professor Ryusuke Niwa, in a joint study with the National Institute of Agrobiological Sciences, has studied Drosophila melanogaster flies to discover a new protein dubbed 'Ouija Board,' which plays an important role in the biosynthesis of the steroid hormones necessary for insect development. (2016-02-08)
Day/night cycle even more important to life than previously suspected
Rhythmic gene expression in intertidal mussels turns out to be driven more by the circadian cycle than the tidal cycle. (2011-09-12)
When butterfly male sex-bias flaps its wings
In butterflies, sex is determined by chromosome differences. But unlike in humans with the familiar X and Y, in butterflies, it is the females that determine the sex of offspring. (2017-07-06)
Researchers find 2 new methods to determine ALK status
Now research published in the August issue of the Journal of Thoracic Oncology, describes the development and evaluation of two new methodologies. (2013-07-01)
NIH completes atlas of human DNA differences that influence gene expression
Researchers from the Genotype-Tissue Expression (GTEx) Consortium, funded by the National Institutes of Health, have completed a detailed atlas documenting the stretches of human DNA that influence gene expression - a key way in which a person's genome gives rise to an observable trait, like hair color or disease risk. (2017-10-11)
RNA measurements may yield less insight about gene expression than assumed
The majority of RNA expression differences between individuals have no connection to the abundance of a corresponding protein, report scientists from the University of Chicago and Stanford University in Science on Dec. (2014-12-18)
Tracking down genetic influences on brain disorders
New findings will help to identify the genetic causes of brain disorders: researchers at the Universities of Basel, Bonn and Cologne have presented a systematic catalog of specific variable locations in the genome that influence gene activity in the human hippocampus, as they report in the journal Nature Communications. (2017-11-27)
New areas of the brain identified where ALS gene is active
For the first time novel expression sites in the brain have been identified for a gene which is associated with motor neuron disease and frontotemporal dementia. (2016-08-01)
Peripheral timekeeping: Mammalian cells outside the brain have their own circadian clocks
Researchers have discovered that individual fibroblast cells contain independent, self-sustaining circadian (ca. (2004-11-23)
Protein protects anti-cancer gene from chemical shutdown
A protein that is largely absent in one type of skin cancer protects an important gene in a cell's defense against harmful mutations from being silenced, researchers at the University of Texas M. (2007-07-19)
Study of bees links gene regulatory networks in the brain to behavior
A new study reveals that distinct networks of genes in the honey bee brain contribute to specific behaviors, such as foraging or aggression, researchers report. (2011-09-26)
'Noisy' genes can have big impact
Experiments by Howard Hughes Medical Institute (HHMI) investigators have revealed how randomness in gene expression can have profound biological effects, both good and bad. (2004-05-27)
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