Genes Current Events

Genes Current Events, Genes News Articles.
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Gag order: how DNA silencing can promote cancer
Methylation of genes effectively silences them, and excess DNA methylation, particularly of cell cycle genes, promotes cancer formation. Here, Rudolf Jaenisch and colleagues investigated DNA methylation in a mouse model of colon cancer. They found that a DNA methylating enzyme, Dnmt3b, targeted specific genes for silencing, and that these genes were similar to those silenced in human tumors. They believe that aberrant DNA methylation may be an initiating event in the development of cancer. (2011-04-01)

Resistance genes discovered in ancestral tomato species
Dutch researcher Marco Kruijt has discovered two resistance genes that were probably present in an ancestral tomato species, prior to the evolution of modern tomato species. The phytopathologist found these same two genes, which provide resistance against a certain fungus, in several wild tomato species. (2004-10-11)

Keeping the cold out
As published in Genes & Development, scientists have cloned and characterized one of the key factors regulating a plant's response to cold temperatures. This factor, HOS-1, is the first protein of its type to be identified in cold signal transduction in any organism. (2001-03-31)

Trapping individual cell types in the mouse brain
A new approach for genetically identifying and manipulating mouse brain cell types. (2016-05-19)

Crime scene schizophrenia -- 30 genes under suspicion
The research group led by Prof. Alex Schier, Director of the University of Basel's Biozentrum, has identified 30 genes associated with schizophrenia. The team was able to show which pathological changes in the brain and behavioral abnormalities are triggered by these genes. The results of the study have now been published in Cell. (2019-03-28)

Rearrangements of multifunctional genes cause cancer in children and young people
A doctoral thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden, shows that three genes that lie behind a number of malignant tumor diseases are normally involved in several fundamental processes in the cell. This may be the reason that the tumors arise early in life and principally affect children and young people. (2009-03-10)

New targets for rabies prevention and treatment
Researchers have identified genes that may be involved in determining whether an individual is sensitive or resistant to rabies virus infection. (2015-03-16)

Study finds new links between number of duplicated genes and adaptation
Liken it to a case of where two genes are better than one. Scientists have found a class of genes, called small-scale duplication genes, or SSDs, that are important for adapting to novel environments and surviving environmental changes. (2014-04-15)

New research: Coffee not associated with lifestyle diseases
Danish researchers are the first in the world to have used our genes to investigate the impact of coffee on the body. The new study shows that coffee neither increases nor decreases the risk of lifestyle diseases. (2015-07-09)

New genetic tool helps researchers to analyze cells' most important functions
Although it has been many years since the human genome was first mapped, there are still many genes whose function we do not understand. Researchers from the University of Gothenburg, Sweden, and the University of Toronto, Canada, have teamed up to produce and characterize a collection of nearly 800 strains of yeast cells that make it possible to study even the most complicated of genes. (2011-04-11)

New developments in mouse genome biology
From fertilized egg to newborn, thousands of genes twinkle on and off in the delicate dance of creation. But developmental genes are difficult to study because of the short time they are active. Now, Minoru Ko (NIH) and colleagues present the sequence of a large segment of the mysterious mouse t- complex, a genome region packed with genes involved in embryonic development. (2000-07-13)

Unravelling the genetics of fungal fratricide
Selfish genes are genes that are passed on to the next generation but confer no advantage on the individual as a whole, and may sometimes be harmful. Researchers at Uppsala University have, for the first time, sequenced (or charted) two selfish genes in the fungus Neurospora intermedia that cause fungal spores to kill their siblings. Unexpectedly, the genes were not related to each other, perhaps indicating that selfish genes are more common than previously thought. (2018-10-15)

K-State researchers study gene regulation in insects
Researchers first identified the genes associated with segmentation and discovered other insects, as well as humans, possessed the genes. But they wondered if the genes functioned the same in every organism. (2006-04-27)

New assay screens human brain organoids, doubles known candidate genes for microcephaly
A new tissue screening assay for human cerebral organoids identified 25 additional candidate genes for microcephaly, nearly doubling the number of currently known genes linked to the rare neurological condition. (2020-10-29)

Taking a SNP in the gene pool: Scientists harvest human gene differences
Scientists are eagerly cataloging human gene variations known as single nucleotide polymorphisms, or SNPs, in the hopes of understanding how differences in our genes lead to differences in us. In the November issue of Genome Research, Kavita Garg, Philip Green, and Deborah Nickerson (University of Washington) report a method to identify common human SNPs located in active genes (1999-11-14)

Search for cancer genes unlikely to succeed, say experts
The hunt to find common genes that are associated with cancer is unlikely to be successful, say experts in this week's BMJ. (2006-05-11)

Suggesting genes' friends, Facebook-style
Scientists at EMBL Heidelberg and the DKFZ have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes can amplify, cancel out or mask each others' effects, and enables scientists to suggest genes that interfere with each other in much the same manner that Facebook suggests friends. (2011-03-07)

Grasses can acquire genes from neighboring plants
Published in the Feb. 18, 2019, edition of Proceedings of the National Academy of Sciences, a study led by an international team including Guillaume Besnard, CNRS researcher at the 'Evolution et diversité biologique' laboratory (CNRS/IRD/Université Toulouse III -- Paul Sabatier), reveals that the genome of Alloteropsis semialata, a grass found in Australia, contains nearly 60 genes acquired from at least nine donor grasses species. (2019-02-18)

Mathematical model identifies genes which battle hepatitis C
A cooperative research project between the University of Haifa and Indiana University yielded the discovery of a mathematical model which identifies genes which battle viruses. Using the method, researchers successfully identified 37 out of 22,000 genes which are active in the battle against the virus hepatitis C, which attacks the liver. (2007-07-19)

Researchers find new genes necessary to make embryo
Researchers at New York University and the medical schools at Harvard and Yale universities have identified new genes necessary for embryonic development, according to findings published in the latest issue of Genome Research. This discovery is an important step toward a complete mapping of which parts of the genome are required for embryonic development. The new findings also probe into how genetic networks are built and how they could evolve. (2005-01-31)

Estimating Alzheimer's disease causative genes by an evolutionary medicine approach
A new approach to finding Alzheimer's disease (AD) causative genes was estimated by paying attention to special duplicated genes called 'ohnologs' included in the genomic region specific to AD patients.Human ohnologs, which are vulnerable to change in number, were generated by whole genome duplications 500 million years ago. (2017-06-27)

Good-looking birds: Sexual attractiveness in the wild turkey
Why are some individuals more attractive to the opposite sex than others? New research by a team from University College London and Oxford University, published in PLOS Genetics, has shown that in wild turkeys, the essence of male beauty is mainly dependent on the way that males use their genes, rather than differences in the genes themselves. (2013-08-15)

Scientists close in on genes responsible for Parkinson's disease
Scientists have identified 570 genes that act abnormally during the development of Parkinson's disease, a finding which could help doctors predict the likelihood of it developing, and provide targets for new treatments. (2005-12-19)

'Sloppy genes' behave like their neighbours
Groundbreaking research in Journal of Biology challenges the traditional view of how genes are controlled. Our current understanding of gene expression, the process by which proteins are made from the instructions encoded in DNA, is that it is tightly controlled so that the correct amount of each protein is produced in the right place at the right time. This new research indicates that some groups of genes that are located next to each other on chromosomes are routinely expressed together. (2002-06-18)

Helping medical researchers classify genes
Medical researchers may soon be getting a helping hand when it comes to identifying genes that are linked to illnesses, thanks to a new micro-array software program developed by a University of Toronto scientist. (2000-11-16)

New antibiotic resistance genes found
Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. The genes were found by searching large volumes of bacterial DNA and the results are published in the scientific journal Microbiome. (2017-10-16)

Scientists ID genes that could lead to tough, disease-resistant varieties of rice
A meta-data analysis has uncovered more than 1,000 genes in rice that appear to play key roles in managing its response to a variety of stress factors, which could make them key to the development of tough new strains of rice. (2014-04-01)

U of MN researchers find novel genes critical in organ development
Researchers at the University of Minnesota have identified a group of novel genes that are critical in organ development. (2006-12-20)

Discovery of a new fusion gene class may affect the development of cancer
Cancer researchers at Lund University in Sweden have discovered a new class of fusion genes with properties that affect and may drive the development of cancer. (2017-10-05)

New species may arise from rapid mitochondrial evolution
Genetic research at has shed new light on how isolated populations of the same species evolve toward reproductive incompatibility and thus become separate species. (2018-07-12)

Technique rapidly reveals individual gene function
A team of researchers led by Leonid Kruglyak have developed a technique using the gene editing system CRISPR to rapidly identify gene variants. (2016-05-05)

Researchers look to imprinted genes for clues to fetal growth restriction in cloned swine
Researchers at North Carolina State University have found that intrauterine growth restriction (IUGR), which results in low birth weight and long-term deleterious health effects in cloned swine, is linked to a type of gene -- known as an imprinted gene -- found only in placental mammals. (2009-07-20)

Genes underscore five psychiatric disorders
A group of international doctors has uncovered the genes that contribute to the development of ADHD, autism spectrum disorder, bipolar disorder, major depression and schizophrenia. (2019-07-24)

Genetic basis for gender differences in the liver
Scientists at the University of Michigan Medical School have identified two genes responsible for an important, yet often overlooked difference between the sexes -- the liver. The report is published in the November 1 issue of Genes & Development. (2003-10-16)

The clustering of Hox genes is not necessary for their proper function
A research group led by Professor Alfredo Ruiz, of the Universitat Autònoma de Barcelona, has found that the Hox gene complex has been rearranged differently in several Drosophila species. The function of Hox genes seems to be conserved despite the rearrangements. Thus Hox gene clustering in the Drosophila genome seems to be the result of evolutionary history more than that of functional necessity. The research will appear in this week's issue of Genome Research. (2005-05-02)

2 genes found to play crucial role in cell survival
New research suggests that two recently discovered genes are critically important for controlling cell survival during embryonic development. The genes, called E2F7 and E2F8, are members of a family of genes that play a fundamental role in development. Members of this family are also involved in cancers of the breast, bladder, stomach and colon. This animal study showed that complete loss of the two genes causes massive cell death and is lethal in developing embryos. (2008-02-04)

Colourful male fish have genes to thank for their enduring looks
Striking colours that are seen only in the males of some species are partly explained by gene behaviour, research into guppy fish suggests. (2019-03-22)

Study identifies genes that protect against aging
Scientists at the University of Liverpool have developed a new method to help researchers identify genes that can help protect the body during the aging process. (2009-04-20)

Stressed-out dust is sharing antibiotic resistance genes
A new Northwestern University study is the first to find that bacteria living in household dust can spread antibiotic resistance genes. Although most bacteria are harmless, the researchers believe these genes could potentially spread to pathogens, making infections more difficult to treat. (2020-01-23)

Yale yeast genome study could lead to further understanding of diseases like cancer
In the largest genome project of its kind to date, Yale scientists have succeeded in fully characterizing the function of the yeast gene, furthering understanding of how human cells work. (1999-11-28)

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