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American Society for Microbiology honors Catherine A. Blish
Catherine A. Blish, M.D., Ph.D., acting instructor in medicine, University of Washington, and associate, Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, has been chosen by the American Society for Microbiology to receive a 2010 ICAAC Young Investigator Award for her outstanding work elucidating the role of neutralizing antibodies in HIV transmission. Sponsored by Merck, US Human Health Division, this award recognizes an early career scientist for research excellence in microbiology and infectious diseases. (2010-08-11)

U of M study shows why treatment isn't effective for HIV
University of Minnesota researchers have answered a key question as to why antiretroviral therapy isn't effective in restoring immunity in HIV-infected patients. Once a person is infected with the virus, fibrosis, or scarring, occurs in the lymph nodes -- the home of T cells that fight infection. And once fibrosis occurs, T cells can't repopulate the lymph nodes when HIV therapy begins, said Timothy Schacker, M.D., professor of medicine and principal investigator on the study. (2008-08-05)

HPV infection high in minority men who have sex with men despite available vaccine
The rate of human papillomavirus (HPV) infection is high among young minority gay, bisexual, and other men who have sex with men despite the availability of a vaccine that can prevent the infection, a Rutgers School of Public Health study found. (2019-04-03)

Hepatitis C negatively impacts HIV
Researchers at Boston Medical Center and Boston University School of Public Health have found that persons infected with the human immunodeficiency virus, who also have alcohol problems, were negatively affected by co-infection with the hepatitis C virus. These findings appear in the June issue of Alcoholism: Clinical Experimental Research. (2007-05-24)

Untreated genital warts may increase risk of HIV transmission
A new study has shown that genital warts may promote HIV sexual transmission and, in turn, their treatment and prevention could help decrease the spread of the disease. (2018-08-21)

Study provides new clues for designing an effective HIV vaccine
New insights into how a promising HIV vaccine works are provided in a study published by Cell Press January 10th in the journal Immunity. By analyzing the structure of antibody-virus complexes produced in vaccine recipients, the researchers have revealed how the vaccine triggers immune responses that could fight HIV-1 infection. The study could help guide efforts to increase the vaccine's production, which currently is not high enough for clinical use. (2013-01-10)

Living, and giving life, with HIV
David Burdge and colleagues present the latest Canadian consensus guidelines that provide evidence-based recommendations to practitioners involved in all stages of pregnancy management of HIV patients, including the proper care for their infants. (2003-06-23)

Genetic amplification (NAAT) test detects HIV more effectively than standard tests in urban study
Adding a new HIV screening method, called nucleic acid amplification testing (NAAT), to standard HIV testing, researchers were able to uncover six percent more cases of HIV infection in urban STD and drug treatment clinics and HIV testing sites in Atlanta than with standard HIV antibody tests alone. (2005-02-25)

Increased prevalence of HIV: Not a casualty of war
Conflict, forced displacement and wide-scale rape have not increased the prevalence of HIV in sub-Saharan Africa, conclude the authors of an article in this week's issue of the Lancet. Furthermore, there are no data to show that refugees fleeing conflict spread HIV infection in host communities; the reverse may be the case. (2007-06-28)

Smoking increases papillomavirus risk in HIV-infected women
Women with HIV infection who smoke are more likely than women not infected with HIV to acquire and have prevalent human papillomavirus (HPV) infection, according to a study published in the May 1 issue of The Journal of Infectious Diseases, now available online. (2004-04-29)

A bad buzz: Men with HIV need fewer drinks to feel effects
Researchers at Yale and the VA Pittsburgh Healthcare System compared the number of drinks that men with HIV infection, versus those without it, needed to get a buzz. They found that HIV-infected men were more sensitive to the effects of alcohol than uninfected men. (2015-04-20)

One step closer to rotavirus vaccination for children with HIV
Results of a hospital-based study in Malawi published in this week's issue of THE LANCET suggest that children with HIV infection could potentially benefit from vaccination against rotaviruses, the main cause of severe, dehydrating diarrhoea in infants and young children throughout the world. (2001-08-16)

A dangerous precedent in HIV
Infection with HIV could quadruple in certain populations if people with HIV follow potentially misleading advice contained in a statement from the Swiss Federal Commission for HIV/AIDS, University of New South Wales research warns. (2008-07-28)

Mathematical modeling uncovers mysteries of HIV infection in the brain
After uncovering the progression of HIV infection in the brain thanks to a new mathematical model developed by a UAlberta research team, clinicians and researchers are developing a nasal spray to administer drugs more effectively. (2017-06-19)

Herpes drug inhibits HIV in patients infected with both viruses
Researchers at the US National Institutes of Health, McGill University and other institutions have discovered how a simple antiviral drug developed decades ago suppresses HIV in patients who are also infected with herpes. Their study was published in the Sept. 11 issue of the journal Cell Host and Microbe. (2008-09-15)

NIH-funded study shows early brain effects of HIV in mouse model
A new mouse model closely resembles how the human body reacts to early HIV infection and is shedding light on nerve cell damage related to the disease, according to researchers funded by the National Institutes of Health. (2011-03-02)

Immediate HIV treatment initiation: Increased but not yet universal in NYC
A new study published in the Journal of Infectious Diseases found that immediate treatment initiation for HIV infection has improved since local and federal guidelines began to recommend universal treatment for all persons diagnosed with HIV, regardless of their disease stage. (2019-05-06)

Individual genotype influences effectiveness of HIV vaccine
A new study in the Journal of Clinical Investigation reveals that an individual's genotype correlates with their ability to develop immunity to HIV in response to vaccination. (2014-08-08)

Early temporary treatment for HIV can delay the time to long-term treatment
A study in this week's PLoS Medicine suggests that when people are first infected with HIV, temporary treatment with antiretroviral drugs for 24 weeks can delay the need to restart treatment during chronic HIV infection. (2012-03-27)

Tracking down T cell targets to tamp down HIV infection
Scientists have narrowed in on a group of gut-residing immune cells that might predispose women to increased HIV infection risk and more severe disease. (2018-01-24)

An HIV vaccine is within reach
An effective, affordable, and accessible HIV vaccine is 7-10 years away, according to scientists at the Medical Research Council of South Africa, in this week's BMJ. However, its success depends on a complex interplay of politics, science, and public-private partnerships. (2002-01-24)

Transplant drugs may help wipe out persistent HIV infections
New research suggests that drugs commonly used to prevent organ rejection after transplantation may also be helpful for combating HIV. The findings, which are published in the American Journal of Transplantation, suggest a new strategy in the fight against HIV and AIDS. (2014-04-03)

HIV testing should no longer be accorded any special status
HIV testing should no longer be accorded any special status, argue two senior doctors in this week's BMJ. (2005-03-03)

MS drug may be used to inhibit hiv infection and reduce latent reservoir
A multiple sclerosis drug may be used to block HIV infection and reduce the latent reservoir, according to research published in PLOS Pathogens by a team at the RGeorge Washington University. (2020-08-13)

Researchers find alcohol plays no role in disclosing HIV status among Russians
Disclosure of HIV positive serostatus to sexual partners is considered an important public health goal to prevent new infections. Disclosure can motivate sex partners to make informed choices and change behavior through negotiation of safer sex practices. It might also prompt partner testing and counseling. (2012-06-11)

HIV exhausts the immune system through chronic non-specific activation
HIV infects the very cells that coordinate the immune response, which compromises the immune system and leaves the body susceptible to normally harmless microorganisms. Victor Appay and colleagues now show that one consequence of persistent HIV infection is generally elevated immune activation. Rather than being beneficial to the host, this causes non-specific premature maturation of many of the remaining functional T-cells. The resulting exhaustion of the immune system increase the likelihood of opportunistic infection. (2004-02-17)

Contaminated needles not contributing to spread of HIV in Africa
Injections with dirty or contaminated needles are not contributing to the spread of HIV in sub-Saharan Africa. (2005-02-22)

UW scientists discover why human body cannot fight HIV infection
University of Washington researchers have made a discovery that sheds light on why the human body is unable to adequately fight off HIV infection. The researchers in the Gale Lab discovered that the viral protein vpu, which is created by HIV during infection, directly interferes with the immune response protein IRF3 to dampen the ability of the immune system to protect against virus infection. (2012-07-11)

Treatment difficult for HIV-infected street youth
Toronto street youth are especially vulnerable to HIV infection and their lifestyles hinder efforts to prevent the spread of the disease, says a study in the Journal of Adolescent Health. (1999-12-12)

Sugar-binding protein may play a role in HIV infection
Researchers report that a sugar-binding protein called galectin-9 traps PDI on T-cells' surface, making them more susceptible to HIV infection. (2011-06-14)

HIV group N case detected outside Cameroon for the first time
A rare type of HIV-infection -- group N -- has been diagnosed in a man in France who recently traveled to Togo, meaning that it has been detected outside Cameroon for the first time. This type of HIV infection is much more similar to the virus type found in chimpanzees than it is to other types circulating in humans. (2011-11-24)

Keeping young South Africans in school: A 'social vaccine' against AIDS
A study published today in the Journal of Epidemiology and Community Health suggests that secondary school attendance is linked to lower risk of HIV infection among young people in rural South Africa. (2008-01-16)

U of T study shows barriers to HIV vaccine acceptance
Public health officials must be sensitive to concerns about stigma and fear of vaccine-induced infection if they want women to take advantage of HIV vaccines now under development, says a University of Toronto researcher. (2005-07-18)

Harvard scientists solve mystery about why HIV patients are more susceptible to TB infection
Harvard scientists took an important first-step toward the development of new treatments to help people with HIV battle Mycobacterium tuberculosis infection. In a report appearing in the July 2009 print issue of the Journal of Leukocyte Biology they describe how HIV interferes with the cellular and molecular mechanisms used by the lungs to fight TB infection. This information is crucial for researchers developing new treatments. (2009-06-30)

Men, women and HIV
Injection drug use has been recognized as one of the major routes of HIV transmission. However, in a cohort of injection drug users in Montreal, Julie Bruneau and colleagues determined sex-related differences in risk behaviour could have implications for the development of preventive and clinical interventions. (2001-03-19)

Scientists took another step towards creating an HIV vaccine
Scientific group of Peter the Great St. Petersburg Polytechnic University headed by Professor Andrei Kozlov published the results of a study devoted to the search of solutions for creating the HIV vaccine. During two years, with the support of the Russian Science Foundation's grant, researchers studied features of transmitted variants of HIV-1 virus. This type of HIV transmission is most typical for Russian Federation. (2018-07-30)

Molecule on immune cells linked to sexual transmission of HIV
Scientists have long suspected that HIV hijacks immune cells called dendritic cells to infiltrate the immune system. Now UCLA AIDS Institute researchers have shown that blocking HIV's access to a naturally occurring molecule on dendritic cells may cut their ability to smuggle the virus into other immune cells. Published in the May edition of the Journal of Virology, the discovery may lead to new drugs to prevent sexually transmitted HIV infection. (2005-04-21)

Antiviral From Advanced Viral Research Corp. Inhibits CCR5 Cell Receptor For HIV
Yonkers, NY, February 25, 1999 - Advanced Viral Research Corp. (OTC BB:ADVR) announced today that its scientists have discovered that its lead antiviral drug, Reticulose, inhibited the production of a key cellular receptor for HIV. (1999-02-25)

How TRIM5 fights HIV
Thanks to a certain protein, rhesus monkeys are resistant to HIV. Known as TRIM5, the protein prevents the HI virus from multiplying once it has entered the cell. Researchers from the universities of Geneva and Zurich have now discovered the protein's mechanism, as they report in Nature. This also opens up new prospects for fighting HIV in humans. (2011-04-20)

Younger people, men and those without children more likely to drop out of HIV care in South Africa
Analysis carried out by an academic at Royal Holloway, University of London has revealed that younger people, men and those without children are more likely to stop attending clinics for HIV treatment in South Africa. (2014-02-20)

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