Heart Muscle Current Events

Heart Muscle Current Events, Heart Muscle News Articles.
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Heart derived stem cells develop into heart muscle
Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells. A breakthrough in stem cell research. Until now, it was necessary to use embryonic stem cells to make this happen. The findings are published in the latest issue of the journal Stem Cell Research. (2008-04-23)

Key finding in rare muscle disease
A group of researchers has discovered a number of children suffering from rare muscle diseases whose bodies have (2007-01-17)

Heart gene discovery strengthens skeletal disease link
Researchers at Baylor College of Medicine have discovered a fourth gene associated with heart muscle disease that also has a link to skeletal and muscle disorders. This discovery strenghens the connection between conditions such as muscular dystrophy and heart failure. (2001-03-04)

Could a noncoding RNA be a new drug target for heart disease?
A new study uncovers a type of noncoding RNA that drives heart failure in mice as a potential therapeutic target for heart disease. (2016-02-17)

New technique may help regenerate heart cells to treat heart disease
Researchers have developed a new technique that might one day be used to convert cells from heart disease patients into heart muscle cells that could act as a personalized treatment for their condition. The research is published online on Aug. 22 in the journal of the International Society of Stem Cell Research, Stem Cell Reports, published by Cell Press. (2013-08-22)

Mayo Clinic proves new heart muscle cells can come from bone marrow
Mayo Clinic researchers have proven for the first time that cells produced by the bone marrow can form new heart-muscle cells in adults, providing an important boost to research that could enable the body to replace heart muscle damaged by heart attack. The findings are now available online and will be published tomorrow in Circulation: Journal of the American Heart Association. (2003-03-10)

Bleeding hearts revealed with new scan
Images that for the first time show bleeding inside the heart after people have suffered a heart attack have been captured by scientists, in a new study published today in the journal Radiology. The research shows that the amount of bleeding can indicate how damaged a person's heart is after a heart attack. (2009-01-19)

New mechanism controlling proper organization of the muscle contractile units indentified
Muscle-specific protein cofilin-2 controls the length of actin filaments in muscle cells. (2014-11-07)

A coordinated response to cardiac stress
In this issue of the Journal of Clinical Investigation, Daniela Tirziu and researchers at Yale University identified a molecular mechanism by which the growth of new blood vessels (angiogenesis) and heart muscle growth are coordinated. (2013-03-01)

Researchers identify key step in cocaine-induced heart enlargement, sudden death
Cocaine, in concentrations commonly sold on the street, causes the abnormal buildup of primitive proteins in heart muscle -- a process that can ultimately lead to sudden death, a new study reports. (2006-09-07)

Muscular heart failure patients may have a better chance at survival: U of A study
University of Alberta researcher Antigone Oreopoulos found that heart failure patients with more muscle have the potential to increase their length of life. (2010-07-21)

Metabolic syndrome significantly boosts risk of heart failure in middle age
Metabolic syndrome significantly boosts the chances of heart failure in middle age, suggests research published ahead of print in Heart. (2006-05-21)

No new heart muscle cells in mice after the newborn period
A new study from Sweden's Karolinska Institutet shows that new heart muscle cells in mice are mainly formed directly after birth. After the neonatal period the number of heart muscle cells does not change, and heart growth occurs only by cell size increase, similar to the human heart. The results are presented in the journal Cell. (2015-11-05)

Body builders aren't necessarily the strongest athletes
An increase in muscle size with exercise may not be directly related to an increase in muscle strength, according to a recent analysis of the literature. (2016-11-03)

Adult stem cell therapy for heart failure proves promising
A new stem cell technique holds exciting potential for treating life-threatening heart failure, Canadian researchers reported today at the American Heart Association's Scientific Sessions 2000. (2000-11-11)

Bioengineered miniature structures could prevent heart failure
The delivery of tiny biodegradable microstructures to heart tissue damaged by heart attack may help repair the tissue and prevent future heart failure. (2015-02-04)

Stem cells train heart following heart attack
Injecting adult stem cells into a heart following a heart attack (infarction) improves the heart function and strengthens the heart wall. The use of such cells may eventually reduce the chance of heart failure following a heart attack. Researchers from Leiden University discovered this in a project forming part of the Dutch Program for Tissue Engineering, funded by Technology Foundation STW and the Netherlands Organization for Health Research and Development. (2007-11-27)

From fruit fly wings to heart failure -- why Not(ch)?
Scientists at the European Molecular Biology Laboratory in Monterotondo, Italy, are the first to prove that the Notch signaling pathway targets heart muscle cells and thus reveal its crucial role in heart development and repair. (2009-12-10)

How do you mend a broken heart?
Scientists are closing in on signals that may be able to coax the heart into producing replacement cardiac muscle cells. Using a zebrafish model system, researchers have identified a family of molecules that can stimulate stem cells to develop into beating heart muscle cells. The research, published by Cell Press in the Dec. 21 issue of the journal Chemistry & Biology, may pave the way towards new therapeutic approaches for cardiac regeneration and repair. (2011-12-22)

ESC Congress: Converting cells into heart muscle
Transdifferentiation means converting one sort of cell, e.g. fibroblast, into another, e.g. muscle cell. There is real hope that we may be able to control this unique phenomenon to produce many heart cells to create a new heart muscle based on cells harvested from the patient himself. (2004-08-31)

Discovery that heart cells replicate during adolescence opens new avenue for heart repair
It is widely accepted that heart muscle cells in mammals stop replicating shortly after birth, limiting the ability of the heart to repair itself after injury. A new study shows that heart muscle cells in mice undergo a burst prior to adolescence to allow for a period of rapid growth. The findings suggest that thyroid hormone therapy could stimulate this process and enhance the heart's ability to regenerate in patients with heart disease. (2014-05-08)

Heart failure therapy hope as drug blocks deadly muscle scarring
A potential treatment to prevent deadly muscle scarring that contributes to chronic heart failure has been uncovered by scientists at the University of Edinburgh. (2017-10-24)

The heart's own stem cells play their part in regeneration
Sca1 stem cells replace steadily aging heart muscle cells. (2013-11-28)

A built-in source for new heart cells
In heart disease, cardiac muscle gradually dies off and, with little or no way to regenerate those cells, that can ultimately lead the heart to fail. But scientists reporting in the Aug. 6 issue of Cell, a Cell Press publication, might have found a way to fix those losses. They've devised a three-ingredient molecular cocktail that transforms fibroblasts -- structural cells that the heart is chock full of -- directly into beating heart cells. (2010-08-05)

Enzyme increases number, size of heart muscle cells in mice
Mice that were genetically engineered to produce a protein found in embryos and stem cells produce more as well as bigger heart cells, which live longer than those in normal mice, according to scientists at Baylor College of Medicine. (2001-08-20)

Pitt and University of Chicago researchers uncover process behind heart muscle contraction
Researchers from the University of Pittsburgh and the University of Chicago were able to control heart muscle function in a new way after discovering the previously unknown role of two enzymes in heart muscle contraction, as detailed in the April 11 cover story of the Journal of Biological Chemistry. (2008-04-09)

Heart attack treatment might be in your face
Researchers at the University of Cincinnati have received $2.4 million in federal funding to pursue research on a novel cell therapy that would repair heart damage using modified cells taken from the patient's own facial muscle. (2017-02-07)

Heart attack in a laboratory dish
NWO researchers at Utrecht University have given heart muscle cells a heart attack in the laboratory. This allowed them to observe clearly the change that takes place in the cell membrane during an attack and how the change sometimes leads to the death of the cell. (2001-05-07)

Attacking heart failure in the young
The inaugural Riley Heart Center Symposium on Cardiac Development will be held Sept. 8-9 at Riley Hospital for Children in Indianapolis. (2008-08-19)

Hearts or tails?
A new paper in the October 1 issue of G&D elucidates the genetics of heart formation in the sea squirt, and lends surprising new insight into the genetic changes that may have driven the evolution of the multi-chambered vertebrate heart. (2006-09-30)

Discovery and gene therapy treatment of a novel heart failure mechanism
A key protein that causes heart failure has been revealed through new research from a collaboration based in Kumamoto University, Japan. The protein is secreted by cardiac muscle cells and reduces heart function. Using gene therapy, researchers were able to inhibit the protein production in mice and human iPS cell models. (2016-10-11)

New NIH grant helps MU scientist get to the heart of muscular dystrophy
A new $2.1 million grant from the National Institutes of Health will help develop a treatment that prevents heart muscles from weakening as a result of Duchenne muscular dystrophy. Dongsheng Duan, Ph.D., a Margaret Proctor Mulligan Distinguished Professor in Medical Research at the MU School of Medicine, has demonstrated that cardiac muscle requires different treatment than skeletal muscle. (2010-12-06)

Annals of Internal Medicine, tip sheet, October 1, 2002
A study of Medicare and other government records of 130,099 elderly heart attack patients found that those with kidney disease were at much higher risk for death than other elderly heart attack patients during the month following hospitalization. (2002-09-30)

CNIC researchers discover the molecular mechanisms that produce the heart's contractile structure
The study opens new horizons for the study of striated muscle physiology by unveiling the molecular mechanisms that control the structural identity of the cardiac and skeletal tissues. (2016-05-10)

Sox17 required for steps from embryonic to heart muscle cell
The gene Sox17 is discovered to play a central role in the complicated dance of signals, enzymes and proteins that transform embryonic stem cells into a beating heart muscle cell. (2007-02-26)

Stem cells appear not to turn into heart cells
Two studies published in the online issue of Nature report no evidence to suggest that hematopoietic stem cells, which usually produce blood cells, can turn into heart cells after injection into the heart. These studies raise a cautionary note for interpreting the results of ongoing clinical studies in which hematopoietic stem cells are injected into the heart after a heart attack. (2004-03-21)

Improving clinical use of stem cells to repair heart damage
Presenting at the UK National Stem Cell Network annual science conference July 13, Professor Michael Schneider describes a new approach to treating heart attack and cardiomyopathy using stem cells. (2010-07-13)

Shutting off blood supply to an extremity to protect the heart
Shutting off the blood supply to an arm or a leg before cardiac surgery protects the heart during the operation. Researchers have looked into heart muscle cells of the left chamber of the heart to understand how activation of the body's very own defense mechanisms may protect the heart in times of reduced oxygen supply. (2014-10-24)

Adult stem cell research
The adult mammalian heart has long been viewed as an organ incapable of repairing itself. Now, a study published in the September 19th issue of Cell provides evidence that the adult heart contains stem cells capable of participating in the formation of viable heart tissue. This discovery may lead to the development of a future treatment for millions of heart-attack survivors who suffer heart damage that later leads to cardiac failure. (2003-09-18)

Scientists in Japan design first optical pacemaker for laboratory research
The world's first optical pacemaker is described in an article published today in Optics Express, the Optical Society's open-access journal. A team of scientists at Osaka University in Japan show that powerful, but very short, laser pulses can help control the beating of heart muscle cells. (2008-05-28)

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