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Heart Muscle Current Events, Heart Muscle News Articles.
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New role found for a cardiac progenitor population
In a discovery that could one day lead to an understanding of how to regenerate damaged heart tissue, researchers at the University of California, San Diego have found that parent cells involved in embryonic development of the epicardium -- the cell layer surrounding the outside of the heart -- give rise to three important types of cells with potential for cardiac repair. (2008-05-14)

Mouse model of type 2 diabetes
Scientists from the NIH have developed a mouse model of type 2 diabetes. Type 2 diabetes is a common endocrinological disorder that affects between six and ten percent of the Western world. As published in Genes & Development, scientists have developed an extremely useful model with which to study the pathogenesis of type 2 diabetes, and test potential therapeutic strategies. (2001-07-31)

UA scientist identifies cellular gene signatures for heart muscle regeneration
A research team led by Jared Churko, PhD, director of the University of Arizona iPSC Core in the UA Sarver Heart Center, used a transcriptomic approach -- studying what genes are expressed -- to identify gene signatures of cell subpopulations identified as atrial-like or ventricular-like. This understanding could lead to regenerative therapy discoveries for the millions of people living with damaged heart muscle caused by heart attacks or other chronic heart conditions. (2018-11-30)

Study shows short-term kidney failure in heart patients may not be as detrimental
New research led by UC Health cardiologists shows that while short-term worsening kidney function is frequent among patients with heart failure, these patients also have better outcomes than those who have persistent kidney failure. (2010-07-01)

How the heart sends an SOS signal to bone marrow cells after a heart attack
Exosomes are key to the SOS signal that the heart muscle sends out after a heart attack. Exosomes in the bloodstream carry greatly increased amounts of heart-specific microRNAs -- as seen in both mice and humans. These exosomes preferentially go to progenitor cells in the bone marrow. Inside those cells, the microRNAs turn off a specific gene that allows the progenitor cells to leave the bone marrow and travel to the heart to attempt repairs. (2019-03-13)

Heart failure patients with worst heart function are good candidates for pacemakers
The pacemaker has taken on an increasingly important role in recent years. Originally used to fix electrical abnormalities in people with irregular heart rhythms, it is now in favor for heart failure patients as a way to (2000-07-13)

Researchers find link between common dietary fat, intestinal microbes and heart disease
A new pathway has been discovered that links a common dietary lipid and intestinal microflora with an increased risk of heart disease, according to a Cleveland Clinic study published in the latest issue of Nature. (2011-04-06)

Using a patient's own bone marrow cells can help an ailing heart
In the first study of its kind, researchers have used a person's own bone marrow cells to improve blood flow in otherwise untreatable coronary arteries. (2001-11-13)

Preliminary study finds stem cells in blood restore damaged heart muscle
Based on promising animal data, researchers at the University of Texas M. D. Anderson Cancer Center say that cells taken from a patient's own blood may one day be able to repair heart tissue that has been damaged. (2003-10-20)

Researchers find protein that suppresses muscle repair in mice
Researchers report that a protein known to be important to protein synthesis also influences muscle regeneration and regrowth in an unexpected manner. The discovery, along with the identification of an inhibitor that blocks its effects, could one day lead to new methods for treating disorders that result in muscle weakness and loss of muscle mass, the researchers said. (2019-05-06)

First biologic pacemaker created by gene therapy in guinea pigs
Working with guinea pigs, Johns Hopkins scientists have created what is believed to be the first biologic pacemaker for the heart, paving the way for a genetically engineered alternative to implanted electronic pacemakers. The advance, reported in the Sept. 12 issue of Nature, uses gene therapy to convert a small fraction of guinea pigs' heart muscle cells into specialized (2002-09-11)

Stem cell study seeks to prevent heart failure
University of Rochester Medical Center researchers today announced the launch of a study that will examine whether transplanted stem cells can be safely used to treat damaged heart muscle in patients just after their first heart attack. As part of the fast emerging science of regenerative medicine, labs worldwide are attempting to replace damaged tissue with new cells, much in the same way as salamanders re-grow limbs. (2006-01-23)

New study uncovers mechanisms underlying how diabetes damages the heart
Cardiac complications are the number one cause of death among diabetics. Now a team of scientists has uncovered a molecular mechanism involved in a common form of heart damage found in people with diabetes. (2016-05-26)

Development of more muscular trout could boost commercial aquaculture
A 10-year effort by a URI scientist to develop transgenic rainbow trout with enhanced muscle growth has yielded fish with what have been described as six-pack abs and muscular shoulders that could provide a boost to the commercial aquaculture industry. (2010-03-10)

Researchers use stem cells to regenerate the external layer of a human heart
A process using human stem cells can generate the cells that cover the external surface of a human heart -- epicardium cells -- according to a multidisciplinary team of researchers. (2017-01-11)

UTMB researchers learned how to better combat muscle loss during space flights
A new study from The University of Texas Medical Branch at Galveston has further documented how muscles are affected by reduced gravity conditions during space flight missions and uncovered how exercise and hormone treatments can be tailored to minimize muscle loss for individual space travelers. (2019-06-13)

One Year Follow-Up Of Non-Invasive Angina Treatment Suggests A Lasting Benefit
A new non-surgical treatment for heart patients who experience the crushing chest pain of angina appears to confer lasting pain relief for a year or longer for many who undergo one-hour treatment sessions for several weeks, according to a study presented at the recent American College of Cardiology meeting in Atlanta. (1998-03-31)

Discovery of differences in heart's precursor cells may advance treatment options
Scientists have long thought that the cells that ultimately give rise to the heart all respond to the same cue before turning into the muscle tissue of this vital organ. (2008-04-14)

Another reason for wine lovers to toast resveratrol
Red wine lovers have a new reason to celebrate. Researchers have found a new health benefit of resveratrol, which occurs naturally in blueberries, raspberries, mulberries, grape skins and consequently in red wine. (2016-05-13)

Quorn protein builds muscle better than milk protein
A study from the University of Exeter has found that mycoprotein, the protein-rich food source that is unique to Quorn products, stimulates post-exercise muscle building to a greater extent than milk protein. (2019-07-03)

Zebrafish study with human heart implications
Bony fish like the tiny zebrafish have a remarkable ability that mammals can only dream of: if you lop off a chunk of their heart they swim sluggishly for a few days but within a month appear perfectly normal. How they accomplish this -- or, more importantly, why we can't -- is one of the significant questions in regenerative medicine today. (2010-03-24)

Shivering in the cold? Exercise may protect against muscle fatigue
New research published in The Journal of Physiology highlights how exercise could help people exposed to extreme temperatures protect themselves from the cold. This could be useful for people who live and work in very cold conditions. (2018-08-14)

The secrets behind hummingbirds' flight agility revealed
Which traits best allow hummingbirds to turn on a dime, in midair, at fast speeds? A new study reveals that the most agile hummingbirds owe their nimbleness to muscle capacity and wing morphology. (2018-02-08)

MSU researcher studies ties between cholesterol drugs, muscle problems
A Michigan State University researcher is studying whether the most popular class of cholesterol-lowering drugs may cause muscle problems in users. There is accumulating evidence that the effect statins can have on skeletal muscle -- including muscle weakness, fatigue and deterioration -- is underestimated, said Jill Slade, assistant professor of radiology and osteopathic manipulative medicine at MSU. (2008-11-11)

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue
University at Buffalo researchers have demonstrated for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart failure. (2009-05-28)

Strong communication between brain and muscle requires both having the protein LRP4
Communication between the brain and muscle must be strong for us to eat, breathe or walk. Now scientists have found that a protein known to be on the surface of muscle cells must be present in both tissues to ensure the conversation is robust. (2012-07-11)

Diabetes treatment may lie in helping muscles to burn fat better
Scientists in Sydney and Melbourne have produced results that could silence the current debate about exactly how fat molecules clog up muscle cells, making them less responsive to insulin. The finding is an important milestone in understanding the mechanisms of obesity related insulin resistance, a precursor of Type 2 diabetes. (2009-01-27)

UMass Amherst team makes artificial energy source for muscle
Muscle physiologist Ned Debold and colleagues at UMass Amherst sought an alternative energy source to replace the body's usual one, adenosine triphosphate (ATP). Such a source could control muscle activity, and might lead to new muscle spasm-calming treatments in cerebral palsy, for example, or activate or enhance skeletal muscle function in MS, ALS and chronic heart failure. They report this month that they have made a series of synthetic compounds to serve as alternative energy sources for the muscle protein myosin. (2020-07-13)

New information about heart enzymes could lead to better treatments
New evidence in animals about hormones that regulate blood pressure and heart function could lead to better treatments for humans after heart attacks, say researchers from Wake Forest University Baptist Medical Center. (2004-04-02)

Molecular 'cocktail' transforms skin cells into beating heart cells
scientists at the Gladstone Institutes have devised a new method that allows for the more efficient -- and, importantly, more complete -- reprogramming of skin cells into cells that are virtually indistinguishable from heart muscle cells. These findings, based on animal models and described in the latest issue of Cell Reports, offer newfound optimism in the hunt for a way to regenerate muscle lost in a heart attack. (2014-02-20)

One step closer to an 'exercise pill'
Studies show obese people produce elevated levels of a protein called myostatin. A new study shows suppressing myostatin enhanced muscle mass and dramatically improved markers of heart and kidney health in mice, suggesting a promising avenue for new drugs to counter obesity. (2017-04-25)

Time to take notice and tackle heart failure
Experts have sounded a call to action for policy makers at local, national, and international levels to promote heart failure prevention, improve heart failure awareness among healthcare professionals, ensure equity of care for all patients with heart failure, support and empower patients and their caregivers, and promote heart failure research. (2014-09-02)

Research Sheds New Light On How "Abs" Function
Researchers at the University at Buffalo have shown for the first time that abdominal-muscle fibers have a specific division of labor, with different fibers answering the call to action, depending on the task. The findings shed new light on how the abdominal muscles function during breathing and other tasks. (1996-05-30)

Exercise combats metabolic syndrome in older adults
Researchers at Johns Hopkins have determined that in people age 55 to 75, a moderate program of physical exercise can significantly offset the potentially deadly mix of risk factors for heart disease and diabetes known as the metabolic syndrome. More specifically, the researchers found that exercise improved overall fitness, but the 23 percent fewer cases were more strongly linked to reductions in total and abdominal body fat and increases in muscle leanness, rather than improved fitness. (2004-12-29)

Biceps bulge, calves curve, 50-year-old assumptions muscled aside
The basics of how a muscle generates power remain the same: Filaments of myosin tugging on filaments of actin shorten, or contract, the muscle -- but the power doesn't just come from what's happening straight up and down the length of the muscle, as has been assumed for 50 years. (2013-07-09)

Injection reverses heart-attack damage
Injured heart tissue normally can't regrow, but researchers at Children's Hospital Boston now offer a groundwork for regenerating heart tissue after a heart attack, in patients with heart failure, or in children with congenital heart defects. In this week's Cell, they show that a growth factor involved in the development of the heart and nervous system can spur heart-muscle growth and recovery of cardiac function when injected systemically into animals after a heart attack. (2009-07-23)

Mass. General researchers identify master cardiac stem cell
Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells. (2006-11-22)

Link Between Chlamydia Infections And Heart Disease Reported In Science
A new study shows how Chlamydia infections may be linked to heart disease. The evidence suggests that Chlamydia employs a sneaky tactic known as (1999-02-26)

MRI can predict risk of heart attacks
For the first time, researchers have shown that magnetic resonance imaging (MRI) can predict the risk of heart attacks or cardiac deaths in coronary heart disease patients, according to a report in today's rapid access issue of Circulation: Journal of the American Heart Association. (2002-10-14)

New research links obesity with heart rhythm disorder
University of Adelaide research has shown for the first time that obesity directly causes electrical abnormalities of the heart. (2011-08-15)

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