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Heterochromatin Current Events

Heterochromatin Current Events, Heterochromatin News Articles.
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Heterochromatin assembly in S. pombe
Dr. Craig Peterson and colleagues have identified an S. pombe ubiquitin ligase that is required for heterochromatin formation and gene silencing. (2005-07-14)
The protein that gives identical cells individuality
New insight into a protein's role in regulating tight DNA packing could have implications for combating tumor cell resistance to anti-cancer treatments. (2019-07-16)
Stem cells know how to open up and unwind
Research has revealed a new understanding of how an open genome structure supports the long-term and unrestricted developmental potential in embryonic stem cells. (2016-04-28)
The nanoscopic structure that locks up our genes
For decades, scientists could only speculate about the shape of heterochromatin. (2018-01-11)
Potential new way to suppress tumor growth discovered
Researchers at the University of California, San Diego School of Medicine, with colleagues at the University of Rochester Medical Center, have identified a new mechanism that appears to suppress tumor growth, opening the possibility of developing a new class of anti-cancer drugs. (2013-06-03)
Renegade genes caught red handed
Potentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. (2019-09-16)
Effects of stress can be inherited, and here's how
None of us are strangers to stress of various kinds. (2011-06-23)
Nuclear architecture: What organizes the genome in the nucleus?
Spatial separation of active from inactive fractions of the genome in the cell nucleus is crucial for gene expression control. (2019-06-06)
Dual systems key to keeping chromosomes intact
USC scientists have discovered how two different structural apparatuses collaborate to protect repetitive DNA when it is at its most vulnerable -- while it is being unzipped for replication. (2013-03-07)
The isoforms of the HP1 protein regulate the organization and structure of heterochromatin
Researchers from the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute (IDIBELL), led by Dr. (2017-11-21)
Mechanism for stress-induced epigenetic inheritance uncovered in new study
Researchers at RIKEN have uncovered a mechanism by which the effects of stress in the fly species Drosophila are inherited epigenetically over many generations through changes to the structure of chromatin, the material that makes up the cell nucleus. (2011-06-23)
Making and breaking heterochromatin
Scientists discover two further mechanisms necessary for the formation of heterochromatin. (2012-09-25)
Active deformations of cell nuclei contribute to intra-nuclear architecture formations
A Japanese researcher has investigated the contributions of active deformation dynamics of cell nuclei using the Brownian motion theory. (2015-10-18)
Discovery of a novel chromosome segregation mechanism during cell division
When cells divide, chromosomes need to be evenly segregated. This equal distribution is important to accurately pass genetic information to the next generation. (2017-03-22)
A molecular garbage disposal complex has a role in packing the genome
New research from the Korea Institute of Science and Technology, to be published in the Journal of Biological Chemistry on Oct. (2017-10-10)
TERRAs, the non-coding RNAs that protect telomeres, are important epigenetic regulators
Researchers at the Spanish National Cancer Research Centre (CNIO) have taken an important step forward by discovering that TERRAs play a decisive role in the assembly of telomeric heterochromatin by interacting with components of the Polycomb complex 2 (PRC), an important epigenetic regulator of gene expression. (2018-04-25)
Nuclear membrane repairs the 'dark matter' of DNA
The nuclear membrane isn't just a protective case around the nucleus -- it actually repairs catastrophically broken DNA strands. (2015-10-29)
Cryo-electron microscopy reveals shape of heterochromatin
Scientists from Waseda University, Okinawa Institute of Science and Technology and the National Institute for Basic Biology became the first to successfully visualize the structure of heterochromatin, thanks to high-contrast imaging in cryo-electron microscopy. (2018-01-16)
Researchers discover mechanism that prevents 2 species from reproducing
Cornell researchers have discovered a genetic mechanism in fruit flies that prevents two closely related species from reproducing, a finding that offers clues to how species evolve. (2009-10-26)
Impaired DNA replication can cause epigenetic changes inherited for several generations
Scientists reveal that a fault in the process that copies DNA during cell division can cause epigenetic changes that may be inherited for up-to five generations. (2017-08-16)
St. Jude study yields secrets of chromosome movement
Investigators at St. Jude Children's Research Hospital have used the lowly yeast to gain insights into how a dividing human cell ensures that an identical set of chromosomes gets passed on to each new daughter cell. (2007-06-14)
Keeping chromosomes in check: a new role for heterochromatin
Large changes in the structure of chromosomes are usually fatal for the cell or can lead to genetic diseases such as cancer. (2019-01-24)
Kinetochores prefer the 'silent' DNA sections of the chromosome
The protein complex responsible for the distribution of chromosomes during cell division is assembled in the transition regions between heterochromatin and euchromatin. (2011-07-05)
The world's tiniest first responders
Amid the rise of CRISPR and genome editing, scientists are still learning more about DNA repair and its significance in aging and diseases such as cancer. (2018-06-20)
New study bolsters beliefs about DNA repair
Aucott et al. report the first in vivo experiments on the heterochromatin protein 1 family, which sidles up to silent DNA. (2008-11-17)
'Silent' DNA speaks up for the first time
By moderately raising the temperature of cells, biologists have broken through what was considered an impermeable barrier that kept half the genes in some cells (2001-05-15)
Researchers discover that DNA packaging in living cells is dynamic
Scientists from Imperial College London, the Medical Research Council, Cancer Research UK and the Hammersmith Hospital have discovered an important aspect of how heterochromatin, the wrapping around DNA, works. (2003-01-30)
Aging erodes genetic control, but that's flexible
In yeast at least, the aging process appears to reduce an organism's ability to silence certain genes that need to be silenced. (2013-11-20)
Tight DNA packaging protects against 'jumping genes,' potential cellular destruction
Scientists discovered that the major developmental function of heterochromatin -- a form of tight DNA packaging found in chromosomes -- is likely the suppression of virus-like DNA elements known as transposons or 'jumping genes,' which can otherwise copy and paste themselves throughout the genome, potentially destroying important genes, and causing cancers and other diseases. (2016-09-01)
How yeast chromosomes avoid the bad breaks
Whitehead Institute researchers have discovered how yeast cells protect themselves against a novel type of chromosome fragility that occurs in repeated DNA during meiosis -- the cell division that produces spores in fungi or eggs and sperm in plants and animals. (2011-08-07)
CSHL team solves a protein complex's molecular structure to explain its role in gene silencing
CSHL scientists and their collaborators at St. Jude's Research Hospital have discovered new details of how the various domains of the RNA-Induced Initiation of Transcriptional gene Silencing complex contribute to heterochromatin assembly and gene silencing. (2011-11-13)
CSHL researchers explain process by which cells 'hide' potentially dangerous DNA segments
Heterochromatin is the super-condensed portion of the cell's genetic material that hides unneeded genes and potentially dangerous DNA sequences such as transposons from the cell's DNA-activating machinery. (2009-04-09)
Scientists discover key driver of human aging
Salk Institute findings on premature aging syndrome could lead to way of slowing or reversing the aging process. (2015-04-30)
Live from the scene: Biochemistry in action
Researchers can now watch molecules move in living cells, literally millisecond by millisecond, thanks to a new microscope developed by scientists at EMBL Heidelberg. (2011-08-08)
TET proteins: double agents in DNA methylation prevent catastrophic cancer
In their latest study, published in this week's online issue of Proceedings of the National Academy of Sciences, researchers at La Jolla Institute for Immunology (LJI), reveal how the finely tuned balance between DNA methylation and demethylation prevents genomic instability and cancer. (2019-07-29)
Microscope invented at marine biological laboratory illuminates chromosomal 'dark matter'
Using a microscope invented at the Marine Biological Laboratory (MBL), a collaborative team of biologists, instrument developers, and computational scientists has for the first time measured the density of a relatively inscrutable, highly condensed form of chromosomal material (heterochromatin) that appears in the cells of human beings and other eukaryotes. (2017-09-12)
Hebrew University, American researchers show 'trigger' to stem cell differentiation
A gene which is essential for stem cells' capabilities to become any cell type has been identified by researchers at the Hebrew University of Jerusalem and the University of California, San Francisco. (2009-12-10)
Histone 1, the guardian of genome stability
Genomic instability is the main risk factor for tumor development in humans. (2017-08-18)
Study reveals new role for RNA interference during chromosomal replication
In a new study that appears online in Nature on Oct. (2011-10-16)
Researchers find new mechanism for genome regulation
The mechanisms that separate mixtures of oil and water may also help the organization of a part of our DNA called heterochromatin, according to a new Berkeley Lab study. (2017-06-21)
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